Title: Methamphetamine behavioural senistization in rodents: interactions with selected drugs and gender.
Abstract: Different behavioural rodent models (rat i.v. drug self-administration, mouse agonistic behaviour, open field test,) were used. Behavioural sensitization to metamphetamine was ocnfirmed after repeated pretreatment with methpahetmaine itself but also after MDMA, morphine and cannabinoid CB1 receptor agonist. A higher rewarding effect of methamphetamine was noted in the sensitized animals with estrus-like conditions and attenuated by estrogen deprivation.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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