Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2587991145', 'doi': 'https://doi.org/10.1186/s12859-017-1519-x', 'title': 'ECDomainMiner: discovering hidden associations between enzyme commission numbers and Pfam domains', 'display_name': 'ECDomainMiner: discovering hidden associations between enzyme commission numbers and Pfam domains', 'publication_year': 2017, 'publication_date': '2017-02-13', 'ids': {'openalex': 'https://openalex.org/W2587991145', 'doi': 'https://doi.org/10.1186/s12859-017-1519-x', 'mag': '2587991145', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28193156', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5307852'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-017-1519-x', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-017-1519-x', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-017-1519-x', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5065087757', 'display_name': 'Seyed Ziaeddin Alborzi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90183372', 'display_name': 'Université de Lorraine', 'ror': 'https://ror.org/04vfs2w97', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I90183372']}, {'id': 'https://openalex.org/I4210121838', 'display_name': 'Laboratoire Lorrain de Recherche en Informatique et ses Applications', 'ror': 'https://ror.org/02vnf0c38', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I1326498283', 'https://openalex.org/I4210121838', 'https://openalex.org/I4210159245', 'https://openalex.org/I90183372']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Seyed Ziaeddin Alborzi', 'raw_affiliation_strings': ['Université de Lorraine, LORIA, UMR, Vandœuvre-lès-Nancy, 7503, 54506, France'], 'affiliations': [{'raw_affiliation_string': 'Université de Lorraine, LORIA, UMR, Vandœuvre-lès-Nancy, 7503, 54506, France', 'institution_ids': ['https://openalex.org/I90183372', 'https://openalex.org/I4210121838']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015598896', 'display_name': 'Marie‐Dominique Devignes', 'orcid': 'https://orcid.org/0000-0002-0399-8713'}, 'institutions': [{'id': 'https://openalex.org/I90183372', 'display_name': 'Université de Lorraine', 'ror': 'https://ror.org/04vfs2w97', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I90183372']}, {'id': 'https://openalex.org/I4210121838', 'display_name': 'Laboratoire Lorrain de Recherche en Informatique et ses Applications', 'ror': 'https://ror.org/02vnf0c38', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I1326498283', 'https://openalex.org/I4210121838', 'https://openalex.org/I4210159245', 'https://openalex.org/I90183372']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Marie-Dominique Devignes', 'raw_affiliation_strings': ['Université de Lorraine, LORIA, UMR, Vandœuvre-lès-Nancy, 7503, 54506, France'], 'affiliations': [{'raw_affiliation_string': 'Université de Lorraine, LORIA, UMR, Vandœuvre-lès-Nancy, 7503, 54506, France', 'institution_ids': ['https://openalex.org/I90183372', 'https://openalex.org/I4210121838']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5050082458', 'display_name': 'David W. Ritchie', 'orcid': 'https://orcid.org/0000-0002-0906-7354'}, 'institutions': [{'id': 'https://openalex.org/I4210127166', 'display_name': "Centre Inria de l'Université de Lorraine", 'ror': 'https://ror.org/03fcjvn64', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1326498283', 'https://openalex.org/I4210127166']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'David W. Ritchie', 'raw_affiliation_strings': ['Inria Nancy Grand-Es, Villers-lès-Nancy, 54600, France'], 'affiliations': [{'raw_affiliation_string': 'Inria Nancy Grand-Es, Villers-lès-Nancy, 54600, France', 'institution_ids': ['https://openalex.org/I4210127166']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1690, 'currency': 'GBP', 'value_usd': 2072, 'provenance': 'doaj'}, 'apc_paid': {'value': 1538, 'currency': 'EUR', 'value_usd': 1658, 'provenance': 'openapc'}, 'fwci': 1.072, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.999984, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '18', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12254', 'display_name': 'Prediction of Protein Subcellular Localization', 'score': 0.9947, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12254', 'display_name': 'Prediction of Protein Subcellular Localization', 'score': 0.9947, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10519', 'display_name': 'Mass Spectrometry Techniques with Proteins', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10887', 'display_name': 'Analysis of Gene Interaction Networks', 'score': 0.9913, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/protein-data-bank', 'display_name': 'Protein Data Bank', 'score': 0.62158173}, {'id': 'https://openalex.org/keywords/proteins', 'display_name': 'Proteins', 'score': 0.52072}, {'id': 'https://openalex.org/keywords/protein-identification', 'display_name': 'Protein Identification', 'score': 0.517222}, {'id': 'https://openalex.org/keywords/biomarker-discovery', 'display_name': 'Biomarker Discovery', 'score': 0.508709}, {'id': 'https://openalex.org/keywords/functional-annotations', 'display_name': 'Functional Annotations', 'score': 0.502417}, {'id': 'https://openalex.org/keywords/protein-function-prediction', 'display_name': 'Protein function prediction', 'score': 0.4368766}, {'id': 'https://openalex.org/keywords/refseq', 'display_name': 'RefSeq', 'score': 0.43561476}], 'concepts': [{'id': 'https://openalex.org/C65556437', 'wikidata': 'https://www.wikidata.org/wiki/Q766195', 'display_name': 'Protein Data Bank (RCSB PDB)', 'level': 2, 'score': 0.8546032}, {'id': 'https://openalex.org/C2776321320', 'wikidata': 'https://www.wikidata.org/wiki/Q857525', 'display_name': 'Annotation', 'level': 2, 'score': 0.6790945}, {'id': 'https://openalex.org/C119145174', 'wikidata': 'https://www.wikidata.org/wiki/Q7251429', 'display_name': 'Protein Data Bank', 'level': 3, 'score': 0.62158173}, {'id': 'https://openalex.org/C144292202', 'wikidata': 'https://www.wikidata.org/wiki/Q898273', 'display_name': 'Protein domain', 'level': 3, 'score': 0.57091784}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.52719074}, {'id': 'https://openalex.org/C36503486', 'wikidata': 'https://www.wikidata.org/wiki/Q11235244', 'display_name': 'Domain (mathematical analysis)', 'level': 2, 'score': 0.47007376}, {'id': 'https://openalex.org/C14036430', 'wikidata': 'https://www.wikidata.org/wiki/Q3736076', 'display_name': 'Function (biology)', 'level': 2, 'score': 0.46338022}, {'id': 'https://openalex.org/C207060522', 'wikidata': 'https://www.wikidata.org/wiki/Q7251473', 'display_name': 'Protein function prediction', 'level': 4, 'score': 0.4368766}, {'id': 'https://openalex.org/C151810110', 'wikidata': 'https://www.wikidata.org/wiki/Q7307074', 'display_name': 'RefSeq', 'level': 4, 'score': 0.43561476}, {'id': 'https://openalex.org/C77088390', 'wikidata': 'https://www.wikidata.org/wiki/Q8513', 'display_name': 'Database', 'level': 1, 'score': 0.3889913}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.37124595}, {'id': 'https://openalex.org/C124101348', 'wikidata': 'https://www.wikidata.org/wiki/Q172491', 'display_name': 'Data mining', 'level': 1, 'score': 0.34922254}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.33708507}, {'id': 'https://openalex.org/C47701112', 'wikidata': 'https://www.wikidata.org/wiki/Q735188', 'display_name': 'Protein structure', 'level': 2, 'score': 0.3350376}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.328492}, {'id': 'https://openalex.org/C2986374874', 'wikidata': 'https://www.wikidata.org/wiki/Q8054', 'display_name': 'Protein function', 'level': 3, 'score': 0.26034576}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2055057}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.12556842}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.111053705}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.10831213}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.07881984}, {'id': 'https://openalex.org/C134306372', 'wikidata': 'https://www.wikidata.org/wiki/Q7754', 'display_name': 'Mathematical analysis', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019295', 'descriptor_name': 'Computational Biology', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D057225', 'descriptor_name': 'Data Mining', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D030562', 'descriptor_name': 'Databases, Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004798', 'descriptor_name': 'Enzymes', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}], 'locations_count': 8, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-017-1519-x', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-017-1519-x', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.inria.fr/hal-01466842', 'pdf_url': 'https://inria.hal.science/hal-01466842/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://inria.hal.science/hal-01466842', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5307852', 'pdf_url': 'https://europepmc.org/articles/pmc5307852?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.inria.fr/hal-01466842/file/12859_2017_Article_1519.pdf', 'pdf_url': 'https://hal.inria.fr/hal-01466842/file/12859_2017_Article_1519.pdf', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.inria.fr/hal-01466842/document', 'pdf_url': 'https://hal.inria.fr/hal-01466842/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307852', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28193156', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-017-1519-x', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-017-1519-x', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.41, 'id': 'https://metadata.un.org/sdg/17', 'display_name': 'Partnerships for the goals'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 37, 'referenced_works': ['https://openalex.org/W1486317198', 'https://openalex.org/W1508885706', 'https://openalex.org/W1516459493', 'https://openalex.org/W1593196131', 'https://openalex.org/W1604281503', 'https://openalex.org/W1690919088', 'https://openalex.org/W2051352017', 'https://openalex.org/W2076048958', 'https://openalex.org/W2085277871', 'https://openalex.org/W2090146405', 'https://openalex.org/W2102027645', 'https://openalex.org/W2103310202', 'https://openalex.org/W2104295259', 'https://openalex.org/W2110120447', 'https://openalex.org/W2110325612', 'https://openalex.org/W2116258825', 'https://openalex.org/W2124029832', 'https://openalex.org/W2130479394', 'https://openalex.org/W2132115288', 'https://openalex.org/W2133210805', 'https://openalex.org/W2136134567', 'https://openalex.org/W2146416540', 'https://openalex.org/W2147526198', 'https://openalex.org/W2158698691', 'https://openalex.org/W2158945625', 'https://openalex.org/W2164461702', 'https://openalex.org/W2170463736', 'https://openalex.org/W2171681733', 'https://openalex.org/W2270973704', 'https://openalex.org/W2334960614', 'https://openalex.org/W2471203817', 'https://openalex.org/W2772934464', 'https://openalex.org/W3101903050', 'https://openalex.org/W4211208250', 'https://openalex.org/W4234914623', 'https://openalex.org/W4240895940', 'https://openalex.org/W4249267926'], 'related_works': ['https://openalex.org/W4387804157', 'https://openalex.org/W3181892255', 'https://openalex.org/W2589205199', 'https://openalex.org/W2518314460', 'https://openalex.org/W2152299045', 'https://openalex.org/W2152181687', 'https://openalex.org/W2106612397', 'https://openalex.org/W2090630809', 'https://openalex.org/W2088162897', 'https://openalex.org/W1955025754'], 'abstract_inverted_index': {'Many': [0], 'entries': [1], 'in': [2, 164, 171, 189], 'the': [3, 18, 28, 36, 39, 66, 70, 109, 158, 172, 190], 'protein': [4, 14, 79, 83, 187], 'data': [5], 'bank': [6], '(PDB)': [7], 'are': [8], 'annotated': [9], 'to': [10, 17, 63, 99, 121, 147, 157, 183], 'show': [11], 'their': [12, 24], 'component': [13], 'domains': [15], 'according': [16], 'Pfam': [19, 129], 'classification,': [20], 'as': [21, 23], 'well': [22], 'biological': [25, 40], 'function': [26, 64], 'through': [27], 'enzyme': [29], 'commission': [30], '(EC)': [31], 'numbering': [32], 'scheme.': [33], 'However,': [34], 'despite': [35], 'fact': [37], 'that': [38], 'activity': [41], 'of': [42, 76, 78, 92, 135, 143, 174], 'many': [43, 74], 'proteins': [44], 'often': [45], 'arises': [46], 'from': [47, 61, 154], 'specific': [48], 'domain-domain': [49], 'and': [50, 81, 128], 'domain-ligand': [51], 'interactions,': [52], 'current': [53], 'on-line': [54], 'resources': [55], 'rarely': [56], 'provide': [57], 'a': [58, 96, 116, 133, 141, 148, 168], 'direct': [59], 'mapping': [60], 'structure': [62], 'at': [65, 108, 204], 'domain': [67, 110], 'level.': [68, 111], 'Since': [69], 'PDB': [71, 191], 'now': [72], 'contains': [73], 'tens': [75], 'thousands': [77], 'chains,': [80], 'since': [82], 'sequence': [84], 'databases': [85], 'can': [86, 106], 'dwarf': [87], 'such': [88], 'numbers': [89, 127], 'by': [90], 'orders': [91], 'magnitude,': [93], 'there': [94], 'is': [95, 201], 'pressing': [97], 'need': [98], 'develop': [100], 'automatic': [101], 'structure-function': [102], 'annotation': [103], 'tools': [104], 'which': [105, 192], 'operate': [107], 'This': [112], 'article': [113], 'presents': [114], 'ECDomainMiner,': [115], 'novel': [117], 'content-based': [118], 'filtering': [119], 'approach': [120], 'automatically': [122], 'infer': [123], 'associations': [124, 139, 163, 179], 'between': [125], 'EC': [126, 196], 'domains.': [130], 'ECDomainMiner': [131, 166, 199], 'finds': [132], 'total': [134], '20,728': [136], 'non-redundant': [137], 'EC-Pfam': [138, 162, 175, 178], 'with': [140, 145], 'F-measure': [142], '0.95': [144], 'respect': [146], '"Gold': [149], 'Standard"': [150], 'test': [151], 'set': [152], 'extracted': [153], 'InterPro.': [155], 'Compared': [156], '1515': [159], 'manually': [160], 'curated': [161], 'InterPro,': [165], 'infers': [167], '13-fold': [169], 'increase': [170], 'number': [173], 'associations.': [176], 'These': [177], 'could': [180], 'be': [181], 'used': [182], 'annotate': [184], 'some': [185], '58,722': [186], 'chains': [188], 'currently': [193], 'lack': [194], 'any': [195], 'annotation.': [197], 'The': [198], 'database': [200], 'publicly': [202], 'available': [203], 'http://ecdm.loria.fr/': [205], '.': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2587991145', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}], 'updated_date': '2024-09-17T18:57:48.601524', 'created_date': '2017-02-24'}