Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2568992328', 'doi': 'https://doi.org/10.18632/oncotarget.14538', 'title': 'Biological functions of CDK5 and potential CDK5 targeted clinical treatments', 'display_name': 'Biological functions of CDK5 and potential CDK5 targeted clinical treatments', 'publication_year': 2017, 'publication_date': '2017-01-06', 'ids': {'openalex': 'https://openalex.org/W2568992328', 'doi': 'https://doi.org/10.18632/oncotarget.14538', 'mag': '2568992328', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28077789', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5370047'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.14538', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=14538&path%5B%5D=46391', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=14538&path%5B%5D=46391', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5029045657', 'display_name': 'Alison B. Shupp', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210106595', 'display_name': 'Sidney Kimmel Cancer Center', 'ror': 'https://ror.org/010h6g454', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210106595']}, {'id': 'https://openalex.org/I149251103', 'display_name': 'Thomas Jefferson University', 'ror': 'https://ror.org/00ysqcn41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I149251103']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alison Shupp', 'raw_affiliation_strings': ['Departments of Cancer Biology, Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA'], 'affiliations': [{'raw_affiliation_string': 'Departments of Cancer Biology, Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA', 'institution_ids': ['https://openalex.org/I4210106595', 'https://openalex.org/I149251103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029197376', 'display_name': 'Mathew C. Casimiro', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210157427', 'display_name': 'Baruch S. Blumberg Institute', 'ror': 'https://ror.org/05evayb02', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210157427']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mathew C. Casimiro', 'raw_affiliation_strings': ['Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S Blumberg Institute, Doylestown, PA, USA'], 'affiliations': [{'raw_affiliation_string': 'Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S Blumberg Institute, Doylestown, PA, USA', 'institution_ids': ['https://openalex.org/I4210157427']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5016235708', 'display_name': 'Richard G. Pestell', 'orcid': 'https://orcid.org/0000-0003-3244-8777'}, 'institutions': [{'id': 'https://openalex.org/I4210157427', 'display_name': 'Baruch S. Blumberg Institute', 'ror': 'https://ror.org/05evayb02', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210157427']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Richard G. Pestell', 'raw_affiliation_strings': ['Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S Blumberg Institute, Doylestown, PA, USA'], 'affiliations': [{'raw_affiliation_string': 'Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S Blumberg Institute, Doylestown, PA, USA', 'institution_ids': ['https://openalex.org/I4210157427']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5016235708'], 'corresponding_institution_ids': ['https://openalex.org/I4210157427'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.529, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 87, 'citation_normalized_percentile': {'value': 0.999387, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '8', 'issue': '10', 'first_page': '17373', 'last_page': '17382'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12829', 'display_name': 'Cyclin-Dependent Kinase 4/6 Inhibitors in Breast Cancer', 'score': 0.9944, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10492', 'display_name': 'Regulation and Function of Microtubules in Cell Division', 'score': 0.9939, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cyclin-dependent-kinase-5', 'display_name': 'Cyclin-dependent kinase 5', 'score': 0.8099821}, {'id': 'https://openalex.org/keywords/kinesin-proteins', 'display_name': 'Kinesin Proteins', 'score': 0.48651}], 'concepts': [{'id': 'https://openalex.org/C121738310', 'wikidata': 'https://www.wikidata.org/wiki/Q18248262', 'display_name': 'Cyclin-dependent kinase 5', 'level': 5, 'score': 0.8099821}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5597228}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.353316}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.23891607}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.18274921}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.13867432}, {'id': 'https://openalex.org/C82495950', 'wikidata': 'https://www.wikidata.org/wiki/Q14911732', 'display_name': 'Cyclin-dependent kinase 2', 'level': 4, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D051360', 'descriptor_name': 'Cyclin-Dependent Kinase 5', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016213', 'descriptor_name': 'Cyclins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055162', 'descriptor_name': 'Biocatalysis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D055162', 'descriptor_name': 'Biocatalysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051360', 'descriptor_name': 'Cyclin-Dependent Kinase 5', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D051360', 'descriptor_name': 'Cyclin-Dependent Kinase 5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016213', 'descriptor_name': 'Cyclins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004789', 'descriptor_name': 'Enzyme Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004789', 'descriptor_name': 'Enzyme Activation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D047428', 'descriptor_name': 'Protein Kinase Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D047428', 'descriptor_name': 'Protein Kinase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.14538', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=14538&path%5B%5D=46391', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5370047', 'pdf_url': 'https://europepmc.org/articles/pmc5370047?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370047', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://jdc.jefferson.edu/cgi/viewcontent.cgi?article=1118&context=cbfp', 'pdf_url': 'https://jdc.jefferson.edu/cgi/viewcontent.cgi?article=1118&context=cbfp', 'source': {'id': 'https://openalex.org/S4306401450', 'display_name': 'Jefferson Digital Commons (Thomas Jefferson University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I149251103', 'host_organization_name': 'Thomas Jefferson University', 'host_organization_lineage': ['https://openalex.org/I149251103'], 'host_organization_lineage_names': ['Thomas Jefferson University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28077789', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.14538', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=14538&path%5B%5D=46391', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.8, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 67, 'referenced_works': ['https://openalex.org/W14542710', 'https://openalex.org/W1517027332', 'https://openalex.org/W1548138662', 'https://openalex.org/W1562206355', 'https://openalex.org/W1563116834', 'https://openalex.org/W1791472493', 'https://openalex.org/W1833170350', 'https://openalex.org/W1858610402', 'https://openalex.org/W1868464733', 'https://openalex.org/W1909535318', 'https://openalex.org/W1914313496', 'https://openalex.org/W1932858082', 'https://openalex.org/W1947780601', 'https://openalex.org/W1955181723', 'https://openalex.org/W1969417329', 'https://openalex.org/W1971590501', 'https://openalex.org/W1978182614', 'https://openalex.org/W1984771785', 'https://openalex.org/W1984886327', 'https://openalex.org/W1987630530', 'https://openalex.org/W2002722486', 'https://openalex.org/W2004176156', 'https://openalex.org/W2005592859', 'https://openalex.org/W2009204794', 'https://openalex.org/W2016207732', 'https://openalex.org/W2020826873', 'https://openalex.org/W2021958350', 'https://openalex.org/W2027754216', 'https://openalex.org/W2038901745', 'https://openalex.org/W2039978805', 'https://openalex.org/W2042022467', 'https://openalex.org/W2042268502', 'https://openalex.org/W2045374982', 'https://openalex.org/W2047285619', 'https://openalex.org/W2067205837', 'https://openalex.org/W2070278756', 'https://openalex.org/W2077642972', 'https://openalex.org/W2085648789', 'https://openalex.org/W2089353165', 'https://openalex.org/W2089465156', 'https://openalex.org/W2092971609', 'https://openalex.org/W2103580937', 'https://openalex.org/W2103650256', 'https://openalex.org/W2107561896', 'https://openalex.org/W2109910647', 'https://openalex.org/W2110317837', 'https://openalex.org/W2118334269', 'https://openalex.org/W2118504945', 'https://openalex.org/W2119582763', 'https://openalex.org/W2124159333', 'https://openalex.org/W2125372689', 'https://openalex.org/W2131491901', 'https://openalex.org/W2149001281', 'https://openalex.org/W2149098886', 'https://openalex.org/W2151348737', 'https://openalex.org/W2160227323', 'https://openalex.org/W2162583663', 'https://openalex.org/W2163489834', 'https://openalex.org/W2171367003', 'https://openalex.org/W2187341842', 'https://openalex.org/W2313997748', 'https://openalex.org/W2319990402', 'https://openalex.org/W2468771388', 'https://openalex.org/W2502908858', 'https://openalex.org/W254715052', 'https://openalex.org/W4322703188', 'https://openalex.org/W91182734'], 'related_works': ['https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2748952813', 'https://openalex.org/W2586801360', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166', 'https://openalex.org/W1489783725'], 'abstract_inverted_index': {'//': [0, 52], 'Alison': [1], 'Shupp': [2], '1': [3, 14], ',': [4], 'Mathew': [5], 'C.': [6], 'Casimiro': [7], '2': [8, 13, 31], 'and': [9, 34, 101, 121, 154, 188, 214], 'Richard': [10, 48], 'G.': [11, 49], 'Pestell': [12], 'Departments': [15], 'of': [16, 103, 181, 205, 216], 'Cancer': [17, 23, 33], 'Biology,': [18], 'Medical': [19], 'Oncology,': [20], 'Sidney': [21], 'Kimmel': [22], 'Center,': [24, 38], 'Thomas': [25], 'Jefferson': [26], 'University,': [27], 'Philadelphia,': [28], 'PA,': [29, 44], 'USA': [30, 45], 'Pennsylvania': [32], 'Regenerative': [35], 'Medicine': [36], 'Research': [37], 'Baruch': [39], 'S': [40], 'Blumberg': [41], 'Institute,': [42], 'Doylestown,': [43], 'Correspondence': [46], 'to:': [47], 'Pestell,': [50], 'email:': [51], 'Keywords': [53], ':': [54, 58, 63, 68], 'CDK5,': [55], 'cancer': [56], 'Received': [57], 'October': [59], '22,': [60], '2016': [61, 66], 'Accepted': [62], 'December': [64], '17,': [65], 'Published': [67], 'January': [69], '06,': [70], '2017': [71], 'Abstract': [72], 'Cyclin': [73], 'dependent': [74], 'kinases': [75, 80], 'are': [76, 82, 193], 'proline-directed': [77], 'serine/threonine': [78], 'protein': [79], 'that': [81, 146, 161, 184, 192], 'traditionally': [83], 'activated': [84, 115], 'upon': [85, 116], 'association': [86, 100], 'with': [87, 118, 138, 150, 165], 'a': [88, 96, 119], 'regulatory': [89], 'subunit.': [90], 'For': [91], 'most': [92], 'CDKs,': [93], 'activation': [94], 'by': [95], 'cyclin': [97, 120], 'occurs': [98], 'through': [99], 'phosphorylation': [102, 126], 'the': [104, 202, 212], 'CDK’s': [105], 'T-loop.': [106], 'CDK5': [107, 147, 162, 173, 186, 189, 208], 'is': [108, 112, 201], 'unusual': [109], 'because': [110], 'it': [111, 131, 142], 'not': [113, 123], 'typically': [114], 'binding': [117], 'does': [122], 'require': [124], 'T-loop': [125], 'for': [127, 207], 'activation,': [128], 'even': [129], 'though': [130], 'has': [132], 'high': [133], 'amino': [134], 'acid': [135], 'sequence': [136], 'homology': [137], 'other': [139, 169], 'CDKs.': [140], 'While': [141], 'was': [143], 'previously': [144], 'thought': [145], 'only': [148], 'interacted': [149], 'p35': [151], 'or': [152], 'p39': [153], 'their': [155], 'cleaved': [156], 'counterparts,': [157], 'Recent': [158], 'evidence': [159, 206], 'suggests': [160], 'can': [163], 'interact': [164], 'certain': [166], 'cylins,': [167], 'amongst': [168], 'proteins,': [170], 'which': [171], 'modulate': [172], 'activity': [174, 187], 'levels.': [175], 'This': [176], 'review': [177], 'discusses': [178], 'recent': [179], 'findings': [180], 'molecular': [182], 'interactions': [183], 'regulate': [185], 'associated': [190], 'pathways': [191], 'implicated': [194], 'in': [195, 209], 'various': [196], 'diseases.': [197], 'Also': [198], 'covered': [199], 'herein': [200], 'growing': [203], 'body': [204], 'contributing': [210], 'to': [211], 'onset': [213], 'progression': [215], 'tumorigenesis.': [217]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2568992328', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 16}, {'year': 2020, 'cited_by_count': 13}, {'year': 2019, 'cited_by_count': 13}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 5}], 'updated_date': '2024-09-13T12:59:35.467036', 'created_date': '2017-01-13'}