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'they': [20], 'provide': [21], 'sequence': [22], 'specific': [23], 'immunity': [24], 'against': [25], 'foreign': [26], 'nucleic': [27], 'acids.': [28], 'are': [31, 44, 79], 'activated': [32, 45], 'by': [33], 'viral': [34, 49, 61, 117, 157], 'infection.': [35, 62, 158], 'However,': [36], 'little': [37], 'is': [38, 55], 'known': [39], 'about': [40], 'how': [41, 52], 'response': [47, 155], 'to': [48, 81, 94, 112, 127, 143, 156], 'infection': [50], 'or': [51], 'their': [53], 'expression': [54], 'controlled': [56], 'absence': [59], 'of': [60, 103, 109, 120, 129, 141, 146], 'Here,': [63], 'we': [64], 'demonstrate': [65, 135], 'that': [66], 'both': [67], 'transcriptional': [69, 131, 144], 'regulator': [70], 'Csa3b,': [71], 'type': [74], 'I-A': [75], 'interference': [76, 85, 148], 'complex': [77], 'Cascade,': [78], 'required': [80], 'transcriptionally': [82], 'repress': [83], 'gene': [86, 149], 'cassette': [87, 105, 150], 'archaeon': [90], 'Sulfolobus.': [91], 'Csa3b': [92], 'binds': [93], 'two': [95], 'repeat': [97], 'sites': [98], 'promoter': [101, 114], 'region': [102], 'facilitates': [107], 'binding': [108], 'Cascade': [111, 121], 'region.': [115], 'Upon': [116], 'infection,': [118], 'loading': [119], 'complexes': [122], 'onto': [123], 'crRNA-matching': [124], 'protospacers': [125, 142], 'leads': [126], 'relief': [128], 'repression.': [132], 'Our': [133], 'data': [134], 'a': [136, 153], 'mechanism': [137], 'coupling': [138], 'surveillance': [140], 'regulation': [145], 'thereby': [151], 'allowing': [152], 'fast': [154]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2567387264', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 13}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 4}], 'updated_date': '2024-09-13T12:59:15.228440', 'created_date': '2017-01-06'}