Title: Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS
Abstract: (Neuron 83, 1043–1050; September 3, 2014) In the original online publication of this paper, four authors were mistakenly omitted from the author list: Seok-Yoon Oh, Peter K. Todd, James D. Berry, and Merit E. Cudkowicz. The author list and the Acknowledgments section have been corrected both in the print issue and online. In addition, the print issue indicates one incorrect affiliation for Vincenzo Silani. Instead of affiliations 10 and 11, he is associated with affiliations 9 and 10. This has been corrected in the article online. Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALSSu et al.NeuronAugust 14, 2014In BriefA repeat expansion in C9ORF72 causes frontotemporal dementia and amyotrophic lateral sclerosis, presumably via the expression of repeat-containing RNA (r(GGGGCC)exp). Su et al. find that small molecules targeting r(GGGGCC)exp can block c9FTD/ALS-associated defects and reveal a potential biomarker for c9FTD/ALS. Full-Text PDF Open Archive