Title: Surgical Management of Medullary Thyroid Carcinoma in Pediatric Age
Abstract: Medullary thyroid carcinoma (MTC) is a rare, accounting for 5% of thyroid malignancies. It is a neuroendocrine tumor wich origins from thyroid parafollicular cells. It may be sporadic, mostly in adult patients, or inherited as autosomal dominant pattern, mostly in pediatric patients. As familial cancer, MTC may presented isolated as familial medullary thyroid carcinoma (FMTC) – 10% of cases - or, most often, as part of multiple endocrine neoplasm type 2 (MEN 2A or MEN 2B) syndromes – 90% of cases. Keywords: Adolescent surgery, children surgery, medullary thyroid carcinoma, MEN2A, MEN2B, RET proto-oncogene.
Publication Year: 2016
Publication Date: 2016-12-02
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 9
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