Title: PRESERVATION OF THE CELL-BIOMATERIAL INTERFACE AT THE ULTRASTRUCTURAL LEVEL
Abstract:Studying the tissue-biomaterial interface at the ultrastructural level is not without problems. Dissolution of the biomaterial in one of the dehydration or embedding media causes holes and shatter dur...Studying the tissue-biomaterial interface at the ultrastructural level is not without problems. Dissolution of the biomaterial in one of the dehydration or embedding media causes holes and shatter during sectioning or dislodgement of the biomaterial. The fine tuning of the hardness of both biomaterial and embedding medium, as well as the introduction of butyl-2,3-epoxypropylether as an intermediate between the dehydration series and the Epon resin, improving the impregnation, will solve many of the problems mentioned. With this improved technique good results were obtained with materials ranging from teflon, poly(Lactic acid) and polyurethanes to tissue culture polystyrene. No holes, shatter or dislodgement of the biomaterial was observed.Read More
Publication Year: 1991
Publication Date: 1991-01-01
Language: en
Type: article
Access and Citation
Cited By Count: 3
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot