Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2552756519', 'doi': 'https://doi.org/10.1182/blood.v126.23.4803.4803', 'title': 'Patterns of DNA Methylation and Gene Expression in Higher-Risk Myelodysplastic Syndromes: Predictors of Demethylating Therapy Response', 'display_name': 'Patterns of DNA Methylation and Gene Expression in Higher-Risk Myelodysplastic Syndromes: Predictors of Demethylating Therapy Response', 'publication_year': 2015, 'publication_date': '2015-12-03', 'ids': {'openalex': 'https://openalex.org/W2552756519', 'doi': 'https://doi.org/10.1182/blood.v126.23.4803.4803', 'mag': '2552756519'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/blood.v126.23.4803.4803', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S200071133', 'display_name': 'Blood', 'issn_l': '0006-4971', 'issn': ['0006-4971', '1528-0020'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1182/blood.v126.23.4803.4803', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5058574596', 'display_name': 'Monika Beličková', 'orcid': 'https://orcid.org/0000-0002-9158-881X'}, 'institutions': [{'id': 'https://openalex.org/I4210096318', 'display_name': 'Institute of Haematology and Blood Transfusion', 'ror': 'https://ror.org/00n6rde07', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I4210096318']}], 'countries': ['CZ'], 'is_corresponding': True, 'raw_author_name': 'Monika Belickova', 'raw_affiliation_strings': ['Institute of Hematology and Blood Transfusion, Prague, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Institute of Hematology and Blood Transfusion, Prague, Czech Republic', 'institution_ids': ['https://openalex.org/I4210096318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044809473', 'display_name': 'Anna Jonášová', 'orcid': 'https://orcid.org/0000-0003-0246-1524'}, 'institutions': [{'id': 'https://openalex.org/I4210162037', 'display_name': 'General University Hospital in Prague', 'ror': 'https://ror.org/04yg23125', 'country_code': 'CZ', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210162037']}], 'countries': ['CZ'], 'is_corresponding': True, 'raw_author_name': 'Anna Jonasova', 'raw_affiliation_strings': ['1st Department of Medicine, General University Hospital, Prague, Czech Republic'], 'affiliations': [{'raw_affiliation_string': '1st Department of Medicine, General University Hospital, Prague, Czech Republic', 'institution_ids': ['https://openalex.org/I4210162037']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035060999', 'display_name': 'Jitka Veselá', 'orcid': 'https://orcid.org/0000-0002-1585-6763'}, 'institutions': [{'id': 'https://openalex.org/I4210096318', 'display_name': 'Institute of Haematology and Blood Transfusion', 'ror': 'https://ror.org/00n6rde07', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I4210096318']}], 'countries': ['CZ'], 'is_corresponding': True, 'raw_author_name': 'Jitka Vesela', 'raw_affiliation_strings': ['Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic', 'institution_ids': ['https://openalex.org/I4210096318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081728138', 'display_name': 'Barbora Pejsova', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210096318', 'display_name': 'Institute of Haematology and Blood Transfusion', 'ror': 'https://ror.org/00n6rde07', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I4210096318']}], 'countries': ['CZ'], 'is_corresponding': True, 'raw_author_name': 'Barbora Pejsova', 'raw_affiliation_strings': ['Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic', 'institution_ids': ['https://openalex.org/I4210096318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080019407', 'display_name': 'Jǐŕı Kléma', 'orcid': 'https://orcid.org/0000-0003-1753-9435'}, 'institutions': [{'id': 'https://openalex.org/I44504214', 'display_name': 'Czech Technical University in Prague', 'ror': 'https://ror.org/03kqpb082', 'country_code': 'CZ', 'type': 'education', 'lineage': ['https://openalex.org/I44504214']}], 'countries': ['CZ'], 'is_corresponding': True, 'raw_author_name': 'Jiri Klema', 'raw_affiliation_strings': ['Faculty of Electrical Engineering, Czech Technical University, Prague 2, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Faculty of Electrical Engineering, Czech Technical University, Prague 2, Czech Republic', 'institution_ids': ['https://openalex.org/I44504214']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5086626929', 'display_name': 'Jaroslav Čermák', 'orcid': 'https://orcid.org/0000-0003-0524-9617'}, 'institutions': [{'id': 'https://openalex.org/I4210096318', 'display_name': 'Institute of Haematology and Blood Transfusion', 'ror': 'https://ror.org/00n6rde07', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I4210096318']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'Jaroslav Cermak', 'raw_affiliation_strings': ['Institute of Hematology and Blood Transfusion, Prague, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Institute of Hematology and Blood Transfusion, Prague, Czech Republic', 'institution_ids': ['https://openalex.org/I4210096318']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5058574596', 'https://openalex.org/A5044809473', 'https://openalex.org/A5035060999', 'https://openalex.org/A5081728138', 'https://openalex.org/A5080019407'], 'corresponding_institution_ids': ['https://openalex.org/I4210096318', 'https://openalex.org/I4210162037', 'https://openalex.org/I4210096318', 'https://openalex.org/I4210096318', 'https://openalex.org/I44504214'], 'apc_list': {'value': 5000, 'currency': 'USD', 'value_usd': 5000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': '126', 'issue': '23', 'first_page': '4803', 'last_page': '4803'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11736', 'display_name': 'Histone Deacetylase Inhibitors Research', 'score': 0.9879, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9765, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/decitabine', 'display_name': 'Decitabine', 'score': 0.90027535}, {'id': 'https://openalex.org/keywords/azacitidine', 'display_name': 'Azacitidine', 'score': 0.8321361}, {'id': 'https://openalex.org/keywords/demethylating-agent', 'display_name': 'Demethylating agent', 'score': 0.7813456}, {'id': 'https://openalex.org/keywords/hypomethylating-agent', 'display_name': 'Hypomethylating agent', 'score': 0.5203204}], 'concepts': [{'id': 'https://openalex.org/C2780235182', 'wikidata': 'https://www.wikidata.org/wiki/Q1181878', 'display_name': 'Decitabine', 'level': 5, 'score': 0.90027535}, {'id': 'https://openalex.org/C2776239401', 'wikidata': 'https://www.wikidata.org/wiki/Q416451', 'display_name': 'Azacitidine', 'level': 5, 'score': 0.8321361}, {'id': 'https://openalex.org/C2779277951', 'wikidata': 'https://www.wikidata.org/wiki/Q5255196', 'display_name': 'Demethylating agent', 'level': 5, 'score': 0.7813456}, {'id': 'https://openalex.org/C2780817109', 'wikidata': 'https://www.wikidata.org/wiki/Q954625', 'display_name': 'Myelodysplastic syndromes', 'level': 3, 'score': 0.7450206}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.72476643}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.63559294}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.63061804}, {'id': 'https://openalex.org/C33288867', 'wikidata': 'https://www.wikidata.org/wiki/Q518328', 'display_name': 'Methylation', 'level': 3, 'score': 0.54640585}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5440816}, {'id': 'https://openalex.org/C2776012956', 'wikidata': 'https://www.wikidata.org/wiki/Q17125294', 'display_name': 'Hypomethylating agent', 'level': 5, 'score': 0.5203204}, {'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.4491692}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.37532339}, {'id': 'https://openalex.org/C2780007613', 'wikidata': 'https://www.wikidata.org/wiki/Q546523', 'display_name': 'Bone marrow', 'level': 2, 'score': 0.31565934}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.3146882}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2636296}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.12426984}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.11901462}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/blood.v126.23.4803.4803', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S200071133', 'display_name': 'Blood', 'issn_l': '0006-4971', 'issn': ['0006-4971', '1528-0020'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/blood.v126.23.4803.4803', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S200071133', 'display_name': 'Blood', 'issn_l': '0006-4971', 'issn': ['0006-4971', '1528-0020'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.77, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4286817035', 'https://openalex.org/W2348621912', 'https://openalex.org/W2319910057', 'https://openalex.org/W2316427340', 'https://openalex.org/W2189342016', 'https://openalex.org/W2167485228', 'https://openalex.org/W2065576507', 'https://openalex.org/W2054507167', 'https://openalex.org/W2013806387', 'https://openalex.org/W1974512900'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2552756519', 'counts_by_year': [], 'updated_date': '2024-12-09T17:24:55.882855', 'created_date': '2016-11-30'}