Title: Hydrophobic Interaction Chromatography Media
Abstract:Cellufine MAX Phenyl is useful for the chromatography of hydrophobic proteins. Many proteins have hydrophobic amino acid residues which will interact with the phenyl functional groups. Factors that in...Cellufine MAX Phenyl is useful for the chromatography of hydrophobic proteins. Many proteins have hydrophobic amino acid residues which will interact with the phenyl functional groups. Factors that influence this hydrophobic interaction include salt concentration, temperature, pH, organic solvents and surfactants. Protein adsorption usually occurs at high ionic strength, while elution occurs at lower salt concentrations. This is the opposite and complementary to ion exchange chromatography. This is the opposite of ion exchange chromatography and offers complementary separation benefits.Read More
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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