Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2549221255', 'doi': 'https://doi.org/10.1128/msphere.00257-16', 'title': 'Sfr1, a Tetrahymena thermophila Sfi1 Repeat Protein, Modulates the Production of Cortical Row Basal Bodies', 'display_name': 'Sfr1, a Tetrahymena thermophila Sfi1 Repeat Protein, Modulates the Production of Cortical Row Basal Bodies', 'publication_year': 2016, 'publication_date': '2016-11-17', 'ids': {'openalex': 'https://openalex.org/W2549221255', 'doi': 'https://doi.org/10.1128/msphere.00257-16', 'mag': '2549221255', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27904881', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5112337'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/msphere.00257-16', 'pdf_url': 'https://msphere.asm.org/content/msph/1/6/e00257-16.full.pdf', 'source': {'id': 'https://openalex.org/S4210207018', 'display_name': 'mSphere', 'issn_l': '2379-5042', 'issn': ['2379-5042'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://msphere.asm.org/content/msph/1/6/e00257-16.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5021138800', 'display_name': 'Westley Heydeck', 'orcid': 'https://orcid.org/0000-0002-8706-9865'}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Westley Heydeck', 'raw_affiliation_strings': ['Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA', 'institution_ids': ['https://openalex.org/I188538660']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080377424', 'display_name': 'Alexander J. Stemm-Wolf', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alexander J. Stemm-Wolf', 'raw_affiliation_strings': ['Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA', 'institution_ids': ['https://openalex.org/I188538660']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049260924', 'display_name': 'Janin Knop', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Janin Knop', 'raw_affiliation_strings': ['Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA', 'institution_ids': ['https://openalex.org/I188538660']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049252687', 'display_name': 'Christina C. Poh', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Christina C. Poh', 'raw_affiliation_strings': ['Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA', 'institution_ids': ['https://openalex.org/I188538660']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013146533', 'display_name': 'Mark Winey', 'orcid': 'https://orcid.org/0000-0002-9028-9033'}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mark Winey', 'raw_affiliation_strings': ['Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA', 'institution_ids': ['https://openalex.org/I188538660']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'apc_paid': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'fwci': 0.249, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.575365, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': '1', 'issue': '6', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11879', 'display_name': 'Global Diversity of Microbial Eukaryotes and Their Evolution', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11879', 'display_name': 'Global Diversity of Microbial Eukaryotes and Their Evolution', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11412', 'display_name': 'Ciliopathies: Genetic Disorders Involving Primary Cilia', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10492', 'display_name': 'Regulation and Function of Microtubules in Cell Division', 'score': 0.993, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/basal-body', 'display_name': 'Basal body', 'score': 0.95030195}, {'id': 'https://openalex.org/keywords/centriole', 'display_name': 'Centriole', 'score': 0.77603734}, {'id': 'https://openalex.org/keywords/basal', 'display_name': 'Basal (medicine)', 'score': 0.7333439}], 'concepts': [{'id': 'https://openalex.org/C2777166614', 'wikidata': 'https://www.wikidata.org/wiki/Q1198419', 'display_name': 'Tetrahymena', 'level': 2, 'score': 0.96585125}, {'id': 'https://openalex.org/C131151476', 'wikidata': 'https://www.wikidata.org/wiki/Q809753', 'display_name': 'Basal body', 'level': 4, 'score': 0.95030195}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7854998}, {'id': 'https://openalex.org/C48342290', 'wikidata': 'https://www.wikidata.org/wiki/Q178355', 'display_name': 'Centriole', 'level': 3, 'score': 0.77603734}, {'id': 'https://openalex.org/C2778024521', 'wikidata': 'https://www.wikidata.org/wiki/Q55639806', 'display_name': 'Basal (medicine)', 'level': 3, 'score': 0.7333439}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6318772}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.30890155}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2335059}, {'id': 'https://openalex.org/C20418707', 'wikidata': 'https://www.wikidata.org/wiki/Q189933', 'display_name': 'Microtubule', 'level': 2, 'score': 0.19991562}, {'id': 'https://openalex.org/C115811362', 'wikidata': 'https://www.wikidata.org/wiki/Q189998', 'display_name': 'Flagellum', 'level': 3, 'score': 0.08677164}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.053616136}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/msphere.00257-16', 'pdf_url': 'https://msphere.asm.org/content/msph/1/6/e00257-16.full.pdf', 'source': {'id': 'https://openalex.org/S4210207018', 'display_name': 'mSphere', 'issn_l': '2379-5042', 'issn': ['2379-5042'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/8bc5984034164c4f82ea927b3a321722', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5112337', 'pdf_url': 'https://europepmc.org/articles/pmc5112337?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://escholarship.org/uc/item/8m83870w', 'pdf_url': 'https://escholarship.org/content/qt8m83870w/qt8m83870w.pdf?t=rwc844', 'source': {'id': 'https://openalex.org/S4306400115', 'display_name': 'eScholarship (California Digital Library)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2801248553', 'host_organization_name': 'California Digital Library', 'host_organization_lineage': ['https://openalex.org/I2801248553'], 'host_organization_lineage_names': ['California Digital Library'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112337', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27904881', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/msphere.00257-16', 'pdf_url': 'https://msphere.asm.org/content/msph/1/6/e00257-16.full.pdf', 'source': {'id': 'https://openalex.org/S4210207018', 'display_name': 'mSphere', 'issn_l': '2379-5042', 'issn': ['2379-5042'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'GM 074746'}], 'datasets': [], 'versions': [], 'referenced_works_count': 70, 'referenced_works': ['https://openalex.org/W1481542900', 'https://openalex.org/W1504048311', 'https://openalex.org/W1518355667', 'https://openalex.org/W1523601657', 'https://openalex.org/W1558790570', 'https://openalex.org/W1589408448', 'https://openalex.org/W1616128910', 'https://openalex.org/W1985117787', 'https://openalex.org/W1990100250', 'https://openalex.org/W1993690386', 'https://openalex.org/W1995891092', 'https://openalex.org/W2005616074', 'https://openalex.org/W2008239810', 'https://openalex.org/W2008541773', 'https://openalex.org/W2012283381', 'https://openalex.org/W2012578884', 'https://openalex.org/W2012931395', 'https://openalex.org/W2013362207', 'https://openalex.org/W2018075425', 'https://openalex.org/W2031986088', 'https://openalex.org/W2034091349', 'https://openalex.org/W2034593148', 'https://openalex.org/W2036747263', 'https://openalex.org/W2042378344', 'https://openalex.org/W2047341499', 'https://openalex.org/W2049633713', 'https://openalex.org/W2051198400', 'https://openalex.org/W2055491482', 'https://openalex.org/W206070210', 'https://openalex.org/W2064560920', 'https://openalex.org/W2064963601', 'https://openalex.org/W2072460025', 'https://openalex.org/W2073403450', 'https://openalex.org/W2076140008', 'https://openalex.org/W2077712321', 'https://openalex.org/W2083367733', 'https://openalex.org/W2084366928', 'https://openalex.org/W2095646707', 'https://openalex.org/W2103796418', 'https://openalex.org/W2106802201', 'https://openalex.org/W2111952755', 'https://openalex.org/W2119837695', 'https://openalex.org/W2120973691', 'https://openalex.org/W2123636562', 'https://openalex.org/W2124589223', 'https://openalex.org/W2124831548', 'https://openalex.org/W2133711457', 'https://openalex.org/W2134084617', 'https://openalex.org/W2134805280', 'https://openalex.org/W2135979384', 'https://openalex.org/W2136336124', 'https://openalex.org/W2138310216', 'https://openalex.org/W2139165826', 'https://openalex.org/W2146925389', 'https://openalex.org/W2149643133', 'https://openalex.org/W2152298405', 'https://openalex.org/W2155692695', 'https://openalex.org/W2160807390', 'https://openalex.org/W2161470995', 'https://openalex.org/W2162681116', 'https://openalex.org/W2165822900', 'https://openalex.org/W2166378119', 'https://openalex.org/W2167075028', 'https://openalex.org/W2167859555', 'https://openalex.org/W2182948616', 'https://openalex.org/W2183254714', 'https://openalex.org/W2284168003', 'https://openalex.org/W2321097360', 'https://openalex.org/W2416635751', 'https://openalex.org/W412261021'], 'related_works': ['https://openalex.org/W4212812951', 'https://openalex.org/W2473239821', 'https://openalex.org/W2319616636', 'https://openalex.org/W2318771776', 'https://openalex.org/W2152298405', 'https://openalex.org/W2063581793', 'https://openalex.org/W206070210', 'https://openalex.org/W2051659995', 'https://openalex.org/W2049477499', 'https://openalex.org/W1827733533'], 'abstract_inverted_index': {'Basal': [0], 'bodies': [1, 107], 'and': [2, 27, 36, 68, 90, 108, 145], 'centrioles': [3], 'are': [4, 19, 25], 'structurally': [5], 'similar': [6], 'and,': [7], 'when': [8], 'rendered': [9], 'dysfunctional': [10], 'as': [11, 134, 136], 'a': [12, 83], 'result': [13], 'of': [14, 30, 46, 74, 92, 112, 117, 124], 'improper': [15], 'assembly': [16], 'or': [17], 'maintenance,': [18], 'associated': [20], 'with': [21], 'human': [22], 'diseases.': [23], 'Centrins': [24], 'conserved': [26], 'abundant': [28], 'components': [29], 'both': [31, 143], 'structures': [32], 'whose': [33], 'basal': [34, 64, 93, 106, 118, 127, 140], 'body': [35, 65, 128, 141], 'centriolar': [37], 'functions': [38], 'remain': [39], 'incompletely': [40], 'understood.': [41], 'Despite': [42], 'the': [43, 75, 88], 'extensive': [44], 'study': [45, 73], 'centrins': [47], 'in': [48, 63, 80, 87, 126], 'Tetrahymena': [49, 81, 105], 'thermophila': [50], ',': [51], 'little': [52], 'is': [53], 'known': [54], 'about': [55], 'how': [56], 'centrin-binding': [57, 77, 132], 'proteins': [58], 'contribute': [59], 'to': [60, 103, 115], 'centrin’s': [61], 'roles': [62], 'assembly,': [66], 'stability,': [67], 'orientation.': [69], 'The': [70, 120], 'sole': [71], 'previous': [72], 'large': [76], 'protein': [78], 'family': [79], 'revealed': [82], 'role': [84, 123], 'for': [85], 'Sfr13': [86], 'stabilization': [89], 'separation': [91], 'bodies.': [94, 119], 'In': [95], 'this': [96], 'study,': [97], 'we': [98], 'found': [99], 'that': [100, 131], 'Sfr1': [101, 125], 'localizes': [102], 'all': [104], 'complete': [109], 'genetic': [110], 'deletion': [111], 'SFR1': [113], 'leads': [114], 'overproduction': [116], 'uncovered': [121], 'inhibitory': [122], 'production': [129], 'suggests': [130], 'proteins,': [133], 'well': [135], 'centrins,': [137], 'may': [138], 'influence': [139], 'number': [142], 'positively': [144], 'negatively.': [146]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2549221255', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-09-17T18:46:54.832268', 'created_date': '2016-11-30'}