Publication Information

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'https://openalex.org/W1831586476', 'https://openalex.org/W1967205715', 'https://openalex.org/W1967900480', 'https://openalex.org/W2039945582', 'https://openalex.org/W2042887247', 'https://openalex.org/W2078434121', 'https://openalex.org/W2140380015', 'https://openalex.org/W2194688567', 'https://openalex.org/W2274360660'], 'related_works': ['https://openalex.org/W51950025', 'https://openalex.org/W4237361002', 'https://openalex.org/W3167506058', 'https://openalex.org/W3022438083', 'https://openalex.org/W2895466941', 'https://openalex.org/W2559372680', 'https://openalex.org/W2101490855', 'https://openalex.org/W2082287210', 'https://openalex.org/W2013157572', 'https://openalex.org/W111397060'], 'abstract_inverted_index': {'Malignant': [0, 407], 'pleural': [1, 34, 55, 66, 103, 208, 226, 234, 242, 263, 279, 300, 343, 356, 370, 404, 465, 510, 538, 546, 615, 633, 711, 818, 920, 953, 964, 996], 'effusions': [2, 35, 56, 235, 357, 405, 659, 921, 954], 'are': [3, 69, 107], 'a': [4, 16, 30, 183, 224, 288, 384, 424, 451, 544, 595, 606, 620, 632, 637, 650, 686, 704, 725, 749, 805, 816, 902, 961], 'rare': [5, 184], 'extramedullary': [6, 842, 864, 905], 'manifestation': [7], 'of': [8, 72, 84, 95, 119, 137, 158, 166, 180, 186, 204, 215, 223, 274, 386, 427, 439, 468, 494, 518, 534, 543, 598, 614, 628, 649, 674, 678, 706, 724, 752, 756, 777, 798, 815, 824, 836, 847, 863, 901, 919, 987, 994], 'Waldenström': [9], 'macroglobulinaemia': [10], '(WM)': [11], '(Banwait': [12, 892], 'et': [13, 58, 62, 77, 131, 161, 195, 269, 328, 696, 700, 737, 741, 769, 872, 893], 'al,': [14, 59, 63, 78, 132, 162, 196, 270, 329, 697, 701, 738, 742, 770, 873, 894], '2015),': [15, 895], 'B-cell': [17, 688], 'malignancy': [18], 'characterized': [19], 'by': [20, 105, 191, 412, 524, 728, 980], 'bone': [21], 'marrow': [22], '(BM)': [23], 'infiltration': [24, 104], 'with': [25, 42, 233, 310, 324, 579, 592, 657, 833, 904, 960], 'IgM-secreting': [26], 'lymphoplasmacytic': [27, 408], 'lymphoma.': [28], 'Establishing': [29], 'malignant': [31, 52, 216, 225, 248, 545, 817, 952, 963], 'aetiology': [32, 993], 'for': [33, 252, 257, 283, 319, 354, 392, 499, 514, 522, 800, 811, 859, 969, 982], 'in': [36, 117, 140, 169, 207, 249, 297, 322, 360, 415, 429, 437, 446, 454, 463, 484, 488, 501, 537, 559, 631, 646, 717, 779, 820, 828, 851, 888, 907, 955], 'WM': [37, 106, 120, 159, 192, 217, 231, 367, 629, 837, 849, 884, 937, 956, 958], 'patients': [38, 232, 323, 381, 395, 418, 433, 456, 496, 516, 555, 567, 571, 604, 618, 827, 838, 870, 885, 959], 'is': [39, 143, 358, 831], 'often': [40], 'inconclusive': [41], 'standard': [43], 'diagnostic': [44, 352, 638, 693], 'tests.': [45], 'Cytology': [46], 'generally': [47], 'cannot': [48], 'distinguish': [49], 'between': [50], 'lymphocyte-rich': [51, 658], 'and': [53, 87, 219, 265, 305, 317, 334, 351, 379, 449, 527, 548, 587, 610, 640, 668, 772, 854, 930, 975, 1025], 'non-malignant': [54], '(Kavuru': [57, 695], '1992;': [60, 698], 'Mansoor': [61, 699], '2000).': [64, 702], 'Additionally,': [65], 'fluid': [67, 171, 209, 243, 264, 280, 301, 344, 466, 539], 'specimens': [68], 'typically': [70, 840], 'devoid': [71], 'extensive': [73], 'tumour': [74, 707], 'involvement': [75, 190, 876], '(Alexandrakis': [76], '2004),': [79], 'adversely': [80], 'impacting': [81], 'the': [82, 113, 141, 156, 178, 202, 213, 221, 299, 355, 402, 430, 440, 464, 502, 509, 529, 541, 549, 647, 672, 718, 722, 760, 775, 796, 813, 834, 848, 852, 860, 899, 917, 935, 992, 1002, 1018, 1022, 1027], 'sensitivity': [83], 'flow': [85, 332, 679, 730], 'cytometric': [86], 'gene': [88, 338], 'rearrangement': [89, 340, 443, 683, 734, 746], 'studies.': [90], 'To': [91], 'ensure': [92], 'timely': [93], 'initiation': [94], 'appropriate': [96], 'antineoplastic': [97, 562], 'therapy,': [98], 'methods': [99], 'to': [100, 154, 176, 246, 369, 551, 561, 624, 684, 710, 764, 909, 950, 990], 'reliably': [101], 'detect': [102, 685, 765], 'needed.': [108], 'Recent': [109], 'studies': [110, 341, 942], 'have': [111, 789], 'identified': [112, 229, 411, 423, 483], 'MYD88': [114, 138, 167, 205, 238, 253, 290, 460, 474, 476, 479, 536, 766, 785, 802, 946, 970, 983, 1008], 'L265P': [115, 139, 168, 206, 254, 767, 974], 'mutation': [116, 971, 1009], '>90%': [118], 'patients,': [121, 448], 'though': [122], 'more': [123, 806, 879], 'rarely': [124], 'non-L265P': [125], 'mutations': [126, 294], 'can': [127, 635, 660, 690, 720, 947], 'be': [128, 247, 636, 948, 967], 'present': [129], '(Treon': [130, 871], '2012,': [133], '2015).': [134, 330], 'Clinical': [135], 'detection': [136, 533, 627, 753, 778], 'BM': [142, 266, 306, 485, 504, 525], 'routinely': [144], 'performed': [145, 240, 256, 282, 445, 1007], 'using': [146, 314], 'highly': [147], 'sensitive': [148, 807], 'allele-specific': [149], 'polymerase': [150], 'chain': [151, 337], 'reaction': [152], '(AS-PCR)': [153], 'support': [155, 177], 'diagnosis': [157, 179, 222, 368, 542, 656, 814], '(Xu': [160, 268, 327, 768], '2013).': [163, 271], 'The': [164, 348, 363, 532, 626, 654, 744, 822], 'presence': [165, 214], 'cerebrospinal': [170], 'has': [172, 748], 'also': [173, 346, 482, 877], 'been': [174], 'shown': [175], 'Bing-Neel': [181], 'syndrome,': [182], 'complication': [185], 'central': [187], 'nervous': [188], 'system': [189], 'cells': [193, 409, 630, 708, 850], '(Poulain': [194], '2014).': [197, 874], 'Consequentially,': [198], 'we': [199], 'hypothesized': [200], 'that': [201, 944], 'identification': [203, 723], 'could': [210], 'similarly': [211], 'identify': [212, 951], 'cells,': [218], 'establish': [220, 991], 'effusion.': [227, 997], 'We': [228], '9': [230, 374, 470, 554], 'who': [236, 286, 782, 839], 'had': [237, 287, 382, 612, 783], 'testing': [239, 972], 'on': [241, 260, 342, 397], 'samples': [244, 267, 326, 486], 'suspected': [245, 962], 'nature.': [250], 'AS-PCR': [251, 318, 761, 799, 981], 'was': [255, 281, 373, 444, 461, 481, 512], 'Patients': [258], '1-8': [259], 'both': [261, 298], 'unselected': [262], 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'therapies': [391, 929], 'WM.': [393, 821], 'Three': [394], 'active': [398], 'ibrutinib': [399], 'therapy': [400, 563], 'at': [401], 'developed.': [406], 'cytological': [413, 675], 'evaluation': [414], 'only': [416], 'two': [417, 432], '(2/9,': [419, 434], '22%).': [420], 'Flow': [421], 'cytometry': [422, 680, 731], 'clonal': [425, 452, 687, 726, 913], 'population': [426, 689, 727], 'same': [431, 503, 530], '22%),': [435], 'but': [436, 492, 786], 'none': [438], 'others.': [441], 'IGH': [442, 682, 733, 745, 792], '7': [447], 'revealed': [450, 528], 'pattern': [453], '6': [455], '(6/7,': [457], '86%).': [458], 'Mutated': [459, 473], 'detected': [462], 'sample': [467, 719], '(100%)': [471], 'patients.': [472, 490, 957], '(8': [475], 'L265P,': [477, 977], '1': [478], 'S243N)': [480], 'obtained': [487], 'All': [491, 553, 617, 1021], 'one': [493, 588, 611, 780], 'these': [495], 'wild-type': [498, 521, 825, 868, 979], 'samples.': [505], 'Selected': [506], 'available': [513], 'three': [515, 570], '(all': [517], 'whom': [519], 'examination),': [526], 'genotype.': [531], 'mutated': [535, 784, 801, 945], 'supported': [540], 'effusion,': [547], 'decision': [550], 'treat.': [552], 'experienced': [556], 'improvement': [558], 'response': [560, 623, 908], '(Table': [564], '2).': [565], 'Four': [566], 'ibrutinib,': [569], 'bendamustine': [573], 'alone': [574], '(N': [575, 584], '1)': [577], 'or': [578, 642, 681, 713, 732], 'an': [580, 790], 'anti-CD20': [581], 'monoclonal': [582], 'antibody': [583], 'patient': [589, 781], 'bortezomib': [591], 'dexamethasone.': [593], 'With': [594], 'follow-up': [597], '12·2': [599], 'months': [600], '4·8–36·1),': [602], '8': [603], 'achieved': [605, 619], 'complete': [607], 'resolution': [608], '(89%),': [609], 'stabilization': [613], 'effusions.': [616], 'major': [621], 'systemic': [622], 'therapy.': [625], 'challenge,': [639], 'hinder': [641], 'delay': [643], 'chemotherapy': [644], 'administration': [645], 'absence': [648, 856], 'supportive': [651], 'pathological': [652], 'diagnosis.': [653, 938], 'differential': [655], 'include': [661], 'chylothorax,': [662], 'tuberculosis,': [663], 'chronic': [664], 'congestive': [665], 'heart': [666], 'failure': [667], 'rheumatoid': [669], 'disease,': [670], 'limiting': [671], 'value': [673], 'examination.': [676], 'Use': [677], 'help': [691], 'improve': [692], 'certainty': [694], 'However,': [703], 'paucity': [705], 'due': [709], 'adherence': [712], 'excess': [714], 'normal': [715], 'impede': [721], 'either': [729], 'assay': [735, 747, 762], '(Mansoor': [736], '2000;': [739], 'Alexandrakis': [740], '2004).': [743], 'lower': [750], 'limit': [751], 'orders': [755], 'magnitude': [757], 'less': [758], 'than': [759], 'used': [763, 949], '2013),': [771], 'may': [773, 803, 857, 897, 915], 'explain': [774, 916], 'lack': [776], 'did': [787], 'not': [788], 'identifiable': [791], 'rearrangement.': [793], 'As': [794], 'such,': [795], 'use': [797], 'represent': [804], 'tumour-directed': [808], 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