Studies of Ischemic Preconditioning Mechanisms in Langendorff Rat Heart Model the Impact of Phosphocreatin Kinase and ATP Sensitive Potasium Channels Pharmachological Openers and Blockers on Cardioprotection

Name: Work Video:
Duration: 3 min 30 s
C. Revnic; Carmen Ginghină; Adriana Sarah Nica; Silviu Cristian Voinea; Alexandru Şonea; Cosmin Șonea; Catalina Peña; B. Paltineanu; F. Revnic
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245, 308], '45': [47], 'minutes': [48], 'ischemia': [49], 'followed': [50], '120': [52], 'minute': [53], 'reperfusion': [54], 'we': [55], 'aimed': [56], 'to': [57], 'evaluate': [58], 'role': [60, 95, 294], 'Phosphocreatin': [62], 'Kinase-C': [63], '(PCK)': [64], 'in': [65, 74, 99, 146, 170, 228, 237, 295, 304, 310], 'myocardium': [68], 'and': [69, 87, 91, 127, 219, 250, 271], 'demonstration': [70], 'its': [72], 'involvment': [73], 'path': [76], 'pharmachological': [78, 100, 282, 305], '(PP)': [80, 102, 307], 'using': [82], 'PKC': [83, 248, 290], 'activators': [84, 124], '1,2-dioctanoyl-sn-glycerol': [85], '(DOG)': [86], 'inhibitors': [88], 'chelerythrine': [89], '(CHE)': [90], 'evaluation': [92], 'KATP': [97, 108, 119, 157], 'channels': [98, 120], 'channel': [109, 131, 158, 256], 'opener': [110], '(Cromakalim)': [111], '(CRK)': [112, 132], 'or': [113], 'blocking': [115], 'opening': [117], 'glibenclamide(GLB).': [122], 'The': [123, 194, 215, 241], 'PCK(DOG)': [126], 'K': [129, 212, 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'protection': [231, 262, 274], 'accompanied': [232], 'significant': [235], 'area.': [240], 'finding': [242], 'that': [243, 266, 272, 289], 'treatment': [244], 'gives': [257], 'similar': [259], 'degree': [260], 'infarction': [264], 'seen': [267], 'after': [268], 'this': [273], 'can': [275], 'be': [276], 'blocked': [277], 'provides': [284], 'support': [285], 'for': [286], 'hypothesis': [288], 'plays': [291], 'pivotal': [293], 'preconditioning.': [297], 'Our': [298], 'data': [299], 'may': [300], 'have': [301], 'significance': [303], 'decrease': [309], 'end': [315], 'point.': [316]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2531502661', 'counts_by_year': [], 'updated_date': '2024-12-24T11:58:25.060362', 'created_date': '2016-10-21'}
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