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'disease:AOSD)は高熱(弛張熱),関節症状,皮疹を主徴とした炎症性疾患であり40代を中心とした成人に好発する.自己抗体は通常陰性であり,血清フェリチンの上昇が特徴的である.診断は山口らの分類基準を用いて行い,重症度分類で中等症以上が指定難病の対象となる.合併症として血球貪食症候群が重要である.治療では副腎皮質ステロイドを使用し,難治例では免疫抑制薬を併用する.近年は生物学的製剤の有効性が報告されている.': [4]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2529682283', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-09-19T08:33:13.463816', 'created_date': '2016-10-14'}