Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2529484692', 'doi': 'https://doi.org/10.1056/nejmoa1602252', 'title': 'Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck', 'display_name': 'Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck', 'publication_year': 2016, 'publication_date': '2016-10-09', 'ids': {'openalex': 'https://openalex.org/W2529484692', 'doi': 'https://doi.org/10.1056/nejmoa1602252', 'mag': '2529484692', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27718784', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5564292'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1602252', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1602252?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1602252?articleTools=true', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5086074491', 'display_name': 'Robert L. Ferris', 'orcid': 'https://orcid.org/0000-0001-6605-2071'}, 'institutions': [{'id': 'https://openalex.org/I2801345345', 'display_name': 'Cancer Institute (WIA)', 'ror': 'https://ror.org/01tc10z29', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801345345']}, {'id': 'https://openalex.org/I4210134769', 'display_name': 'University of Pittsburgh Medical Center', 'ror': 'https://ror.org/04ehecz88', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210098814', 'https://openalex.org/I4210134769']}], 'countries': ['IN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Robert L. Ferris', 'raw_affiliation_strings': ['University of Pittsburgh Medical Center and Cancer Institute, Pittsburgh'], 'affiliations': [{'raw_affiliation_string': 'University of Pittsburgh Medical Center and Cancer Institute, Pittsburgh', 'institution_ids': ['https://openalex.org/I2801345345', 'https://openalex.org/I4210134769']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077579849', 'display_name': 'George R. Blumenschein', 'orcid': 'https://orcid.org/0000-0002-9606-8194'}, 'institutions': [{'id': 'https://openalex.org/I1343551460', 'display_name': 'The University of Texas MD Anderson Cancer Center', 'ror': 'https://ror.org/04twxam07', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1343551460']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'George Blumenschein', 'raw_affiliation_strings': ['Department of Thoracic–Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston'], 'affiliations': [{'raw_affiliation_string': 'Department of Thoracic–Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston', 'institution_ids': ['https://openalex.org/I1343551460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028065894', 'display_name': 'Jérôme Fayette', 'orcid': 'https://orcid.org/0000-0002-8126-7019'}, 'institutions': [{'id': 'https://openalex.org/I4210105738', 'display_name': 'Centre Léon Bérard', 'ror': 'https://ror.org/01cmnjq37', 'country_code': 'FR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210105738']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jerome Fayette', 'raw_affiliation_strings': ['Centre Leon Berard, Lyon'], 'affiliations': [{'raw_affiliation_string': 'Centre Leon Berard, Lyon', 'institution_ids': ['https://openalex.org/I4210105738']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008235770', 'display_name': 'J. Guigay', 'orcid': 'https://orcid.org/0000-0002-5654-6411'}, 'institutions': [{'id': 'https://openalex.org/I4210151846', 'display_name': 'Centre Antoine Lacassagne', 'ror': 'https://ror.org/05hmfw828', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210151846']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Joel Guigay', 'raw_affiliation_strings': ['Centre Antoine Lacassagne, Nice'], 'affiliations': [{'raw_affiliation_string': 'Centre Antoine Lacassagne, Nice', 'institution_ids': ['https://openalex.org/I4210151846']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069613777', 'display_name': 'A. Dimitrios Colevas', 'orcid': 'https://orcid.org/0000-0003-3849-4264'}, 'institutions': [{'id': 'https://openalex.org/I1321488844', 'display_name': 'Cancer Prevention Institute of California', 'ror': 'https://ror.org/03bx60s49', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1321488844']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'A. Dimitrios Colevas', 'raw_affiliation_strings': ['Stanford Cancer Institute, Stanford, CA'], 'affiliations': [{'raw_affiliation_string': 'Stanford Cancer Institute, Stanford, CA', 'institution_ids': ['https://openalex.org/I1321488844']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047193688', 'display_name': 'Lisa Licitra', 'orcid': 'https://orcid.org/0000-0003-0623-4118'}, 'institutions': [{'id': 'https://openalex.org/I4210156707', 'display_name': 'Fondazione IRCCS Istituto Nazionale dei Tumori', 'ror': 'https://ror.org/05dwj7825', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4210156707']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Lisa Licitra', 'raw_affiliation_strings': ['Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale Tumori, Milan'], 'affiliations': [{'raw_affiliation_string': 'Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale Tumori, Milan', 'institution_ids': ['https://openalex.org/I4210156707']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072284989', 'display_name': 'Kevin J. Harrington', 'orcid': 'https://orcid.org/0000-0002-6014-348X'}, 'institutions': [{'id': 'https://openalex.org/I34931013', 'display_name': 'National Institute for Health Research', 'ror': 'https://ror.org/0187kwz08', 'country_code': 'GB', 'type': 'government', 'lineage': ['https://openalex.org/I34931013']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Kevin Harrington', 'raw_affiliation_strings': ['Institute of Cancer Research–Royal Marsden National Institute for Health Research Biomedical Research Centre, London'], 'affiliations': [{'raw_affiliation_string': 'Institute of Cancer Research–Royal Marsden National Institute for Health Research Biomedical Research Centre, London', 'institution_ids': ['https://openalex.org/I34931013']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007861447', 'display_name': 'Stefan Kasper', 'orcid': 'https://orcid.org/0000-0002-5947-8733'}, 'institutions': [{'id': 'https://openalex.org/I4210119759', 'display_name': 'Essen University Hospital', 'ror': 'https://ror.org/02na8dn90', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210119759']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Stefan Kasper', 'raw_affiliation_strings': ['University Hospital Essen, Essen, Germany'], 'affiliations': [{'raw_affiliation_string': 'University Hospital Essen, Essen, Germany', 'institution_ids': ['https://openalex.org/I4210119759']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063904421', 'display_name': 'Everett E. Vokes', 'orcid': 'https://orcid.org/0000-0002-8645-8068'}, 'institutions': [{'id': 'https://openalex.org/I40347166', 'display_name': 'University of Chicago', 'ror': 'https://ror.org/024mw5h28', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I40347166']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Everett E. Vokes', 'raw_affiliation_strings': ['University of Chicago, Chicago'], 'affiliations': [{'raw_affiliation_string': 'University of Chicago, Chicago', 'institution_ids': ['https://openalex.org/I40347166']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070634393', 'display_name': 'Caroline Even', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Caroline Even', 'raw_affiliation_strings': ['Institut Gustave Roussy, Villejuif'], 'affiliations': [{'raw_affiliation_string': 'Institut Gustave Roussy, Villejuif', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022036818', 'display_name': 'Francis P. Worden', 'orcid': 'https://orcid.org/0000-0002-6632-4951'}, 'institutions': [{'id': 'https://openalex.org/I27837315', 'display_name': 'University of Michigan–Ann Arbor', 'ror': 'https://ror.org/00jmfr291', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I27837315']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Francis Worden', 'raw_affiliation_strings': ['University of Michigan, Ann Arbor'], 'affiliations': [{'raw_affiliation_string': 'University of Michigan, Ann Arbor', 'institution_ids': ['https://openalex.org/I27837315']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036672833', 'display_name': 'Nabil F. Saba', 'orcid': 'https://orcid.org/0000-0003-4972-1477'}, 'institutions': [{'id': 'https://openalex.org/I150468666', 'display_name': 'Emory University', 'ror': 'https://ror.org/03czfpz43', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I150468666']}, {'id': 'https://openalex.org/I2801345345', 'display_name': 'Cancer Institute (WIA)', 'ror': 'https://ror.org/01tc10z29', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801345345']}], 'countries': ['IN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Nabil F. Saba', 'raw_affiliation_strings': ['Winship Cancer Institute of Emory University, Atlanta'], 'affiliations': [{'raw_affiliation_string': 'Winship Cancer Institute of Emory University, Atlanta', 'institution_ids': ['https://openalex.org/I150468666', 'https://openalex.org/I2801345345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050719764', 'display_name': 'Lara Carmen Iglesias Docampo', 'orcid': 'https://orcid.org/0000-0001-6485-4601'}, 'institutions': [{'id': 'https://openalex.org/I4210101691', 'display_name': 'Hospital Universitario 12 De Octubre', 'ror': 'https://ror.org/00qyh5r35', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210101691', 'https://openalex.org/I4210139293']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Lara C. Iglesias Docampo', 'raw_affiliation_strings': ['Hospital Universitario 12 de Octubre, Madrid'], 'affiliations': [{'raw_affiliation_string': 'Hospital Universitario 12 de Octubre, Madrid', 'institution_ids': ['https://openalex.org/I4210101691']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080875822', 'display_name': 'Robert I. Haddad', 'orcid': 'https://orcid.org/0000-0003-1413-0079'}, 'institutions': [{'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert Haddad', 'raw_affiliation_strings': ['Dana–Farber Cancer Institute, Boston'], 'affiliations': [{'raw_affiliation_string': 'Dana–Farber Cancer Institute, Boston', 'institution_ids': ['https://openalex.org/I4210117453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028180795', 'display_name': 'Tamara Rordorf', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210100468', 'display_name': 'University Hospital of Zurich', 'ror': 'https://ror.org/01462r250', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100468']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Tamara Rordorf', 'raw_affiliation_strings': ['Universitätsspital Zurich, Zurich, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Universitätsspital Zurich, Zurich, Switzerland', 'institution_ids': ['https://openalex.org/I4210100468']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034582186', 'display_name': 'Naomi Kiyota', 'orcid': 'https://orcid.org/0000-0001-8021-6116'}, 'institutions': [{'id': 'https://openalex.org/I4210089895', 'display_name': 'Kobe University Hospital', 'ror': 'https://ror.org/00bb55562', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210089895']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Naomi Kiyota', 'raw_affiliation_strings': ['Kobe University Hospital, Kobe'], 'affiliations': [{'raw_affiliation_string': 'Kobe University Hospital, Kobe', 'institution_ids': ['https://openalex.org/I4210089895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011675274', 'display_name': 'Makoto Tahara', 'orcid': 'https://orcid.org/0000-0001-9035-3106'}, 'institutions': [{'id': 'https://openalex.org/I4210145079', 'display_name': 'National Cancer Center Hospital East', 'ror': 'https://ror.org/03rm3gk43', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210145079']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Makoto Tahara', 'raw_affiliation_strings': ['National Cancer Center Hospital East, Kashiwa'], 'affiliations': [{'raw_affiliation_string': 'National Cancer Center Hospital East, Kashiwa', 'institution_ids': ['https://openalex.org/I4210145079']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072416707', 'display_name': 'Manish Monga', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210091812', 'display_name': 'Bristol-Myers Squibb (United States)', 'ror': 'https://ror.org/00gtmwv55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210091812']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Manish Monga', 'raw_affiliation_strings': ['Bristol-Myers Squibb, Princeton, NJ'], 'affiliations': [{'raw_affiliation_string': 'Bristol-Myers Squibb, Princeton, NJ', 'institution_ids': ['https://openalex.org/I4210091812']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022430976', 'display_name': 'Mark Lynch', 'orcid': 'https://orcid.org/0000-0002-8476-4854'}, 'institutions': [{'id': 'https://openalex.org/I4210091812', 'display_name': 'Bristol-Myers Squibb (United States)', 'ror': 'https://ror.org/00gtmwv55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210091812']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mark Lynch', 'raw_affiliation_strings': ['Bristol-Myers Squibb, Princeton, NJ'], 'affiliations': [{'raw_affiliation_string': 'Bristol-Myers Squibb, Princeton, NJ', 'institution_ids': ['https://openalex.org/I4210091812']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076652172', 'display_name': 'William J. Geese', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210091812', 'display_name': 'Bristol-Myers Squibb (United States)', 'ror': 'https://ror.org/00gtmwv55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210091812']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'William J. Geese', 'raw_affiliation_strings': ['Bristol-Myers Squibb, Princeton, NJ'], 'affiliations': [{'raw_affiliation_string': 'Bristol-Myers Squibb, Princeton, NJ', 'institution_ids': ['https://openalex.org/I4210091812']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034809035', 'display_name': 'Justin Kopit', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210091812', 'display_name': 'Bristol-Myers Squibb (United States)', 'ror': 'https://ror.org/00gtmwv55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210091812']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Justin Kopit', 'raw_affiliation_strings': ['Bristol-Myers Squibb, Princeton, NJ'], 'affiliations': [{'raw_affiliation_string': 'Bristol-Myers Squibb, Princeton, NJ', 'institution_ids': ['https://openalex.org/I4210091812']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055862397', 'display_name': 'James W. Shaw', 'orcid': 'https://orcid.org/0000-0002-7019-3720'}, 'institutions': [{'id': 'https://openalex.org/I4210091812', 'display_name': 'Bristol-Myers Squibb (United States)', 'ror': 'https://ror.org/00gtmwv55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210091812']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James W. Shaw', 'raw_affiliation_strings': ['Bristol-Myers Squibb, Princeton, NJ'], 'affiliations': [{'raw_affiliation_string': 'Bristol-Myers Squibb, Princeton, NJ', 'institution_ids': ['https://openalex.org/I4210091812']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5076901251', 'display_name': 'Maura L. Gillison', 'orcid': 'https://orcid.org/0000-0002-8145-5749'}, 'institutions': [{'id': 'https://openalex.org/I52357470', 'display_name': 'The Ohio State University', 'ror': 'https://ror.org/00rs6vg23', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I52357470']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Maura L. Gillison', 'raw_affiliation_strings': ['Ohio State University, Columbus'], 'affiliations': [{'raw_affiliation_string': 'Ohio State University, Columbus', 'institution_ids': ['https://openalex.org/I52357470']}]}], 'institution_assertions': [], 'countries_distinct_count': 9, 'institutions_distinct_count': 20, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 336.789, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 3988, 'citation_normalized_percentile': {'value': 0.999635, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '375', 'issue': '19', 'first_page': '1856', 'last_page': '1867'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10307', 'display_name': 'Epidemiology and Treatment of Head and Neck Cancer', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2733', 'display_name': 'Otorhinolaryngology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10307', 'display_name': 'Epidemiology and Treatment of Head and Neck Cancer', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2733', 'display_name': 'Otorhinolaryngology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12379', 'display_name': 'Cancer of Unknown Primary Site', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/squamous-cell-carcinoma', 'display_name': 'Squamous-Cell Carcinoma', 'score': 0.504596}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9588767}, {'id': 'https://openalex.org/C2780030458', 'wikidata': 'https://www.wikidata.org/wiki/Q7041828', 'display_name': 'Nivolumab', 'level': 4, 'score': 0.92957413}, {'id': 'https://openalex.org/C3018411727', 'wikidata': 'https://www.wikidata.org/wiki/Q3867488', 'display_name': 'Head and neck', 'level': 2, 'score': 0.7123598}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.6420803}, {'id': 'https://openalex.org/C3019992690', 'wikidata': 'https://www.wikidata.org/wiki/Q92767510', 'display_name': 'Basal cell', 'level': 2, 'score': 0.5914131}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.5885141}, {'id': 'https://openalex.org/C2776833033', 'wikidata': 'https://www.wikidata.org/wiki/Q1783924', 'display_name': 'Head and neck squamous-cell carcinoma', 'level': 4, 'score': 0.53468937}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.52280366}, {'id': 'https://openalex.org/C2776530083', 'wikidata': 'https://www.wikidata.org/wiki/Q1783924', 'display_name': 'Head and neck cancer', 'level': 3, 'score': 0.4766917}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.47373092}, {'id': 'https://openalex.org/C2777546739', 'wikidata': 'https://www.wikidata.org/wiki/Q33525', 'display_name': 'Carcinoma', 'level': 2, 'score': 0.46110588}, {'id': 'https://openalex.org/C163864487', 'wikidata': 'https://www.wikidata.org/wiki/Q6901461', 'display_name': 'Monoclonal', 'level': 4, 'score': 0.42080507}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.38707542}, {'id': 'https://openalex.org/C2777701055', 'wikidata': 'https://www.wikidata.org/wiki/Q1427096', 'display_name': 'Immunotherapy', 'level': 3, 'score': 0.3510762}, {'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.25398135}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.23513806}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.1893338}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.1532377}], 'mesh': [{'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D060890', 'descriptor_name': 'B7-H1 Antigen', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D006258', 'descriptor_name': 'Head and Neck Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D009364', 'descriptor_name': 'Neoplasm Recurrence, Local', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D060890', 'descriptor_name': 'B7-H1 Antigen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060890', 'descriptor_name': 'B7-H1 Antigen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006258', 'descriptor_name': 'Head and Neck Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006258', 'descriptor_name': 'Head and Neck Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009364', 'descriptor_name': 'Neoplasm Recurrence, Local', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077594', 'descriptor_name': 'Nivolumab', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011788', 'descriptor_name': 'Quality of Life', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016019', 'descriptor_name': 'Survival Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1602252', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1602252?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5564292', 'pdf_url': 'https://europepmc.org/articles/pmc5564292?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564292', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27718784', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1602252', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1602252?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.45}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 26, 'referenced_works': ['https://openalex.org/W1547791321', 'https://openalex.org/W1571132164', 'https://openalex.org/W1757407923', 'https://openalex.org/W1947168884', 'https://openalex.org/W1971142107', 'https://openalex.org/W2019607817', 'https://openalex.org/W2029579916', 'https://openalex.org/W2059707463', 'https://openalex.org/W2071606440', 'https://openalex.org/W2089257078', 'https://openalex.org/W2098428600', 'https://openalex.org/W2104347254', 'https://openalex.org/W2120068217', 'https://openalex.org/W2124462445', 'https://openalex.org/W2143772132', 'https://openalex.org/W2145078756', 'https://openalex.org/W2154923100', 'https://openalex.org/W2156353875', 'https://openalex.org/W2160842550', 'https://openalex.org/W2163814058', 'https://openalex.org/W2274310825', 'https://openalex.org/W2320299038', 'https://openalex.org/W2327808934', 'https://openalex.org/W2401455386', 'https://openalex.org/W2572174216', 'https://openalex.org/W4246839970'], 'related_works': ['https://openalex.org/W4321786945', 'https://openalex.org/W3114928796', 'https://openalex.org/W2974748062', 'https://openalex.org/W2955084311', 'https://openalex.org/W2529376761', 'https://openalex.org/W2318228201', 'https://openalex.org/W2092701849', 'https://openalex.org/W2007176132', 'https://openalex.org/W1999686187', 'https://openalex.org/W1993267564'], 'abstract_inverted_index': {'Patients': [0], 'with': [1], 'recurrent': [2], 'or': [3], 'metastatic': [4], 'squamous-cell': [5], 'carcinoma': [6], 'of': [7], 'the': [8], 'head': [9], 'and': [10, 20], 'neck': [11], 'after': [12], 'platinum': [13], 'chemotherapy': [14], 'have': [15], 'a': [16], 'very': [17], 'poor': [18], 'prognosis': [19], 'limited': [21], 'therapeutic': [22], 'options.': [23], 'Nivolumab,': [24], 'an': [25], 'anti–programmed': [26], 'death': [27], '1': [28], '(PD-1)': [29], 'monoclonal': [30], 'antibody,': [31], 'was': [32], 'assessed': [33], 'as': [34], 'treatment': [35], 'for': [36], 'this': [37], 'condition.': [38]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2529484692', 'counts_by_year': [{'year': 2024, 'cited_by_count': 300}, {'year': 2023, 'cited_by_count': 479}, {'year': 2022, 'cited_by_count': 555}, {'year': 2021, 'cited_by_count': 645}, {'year': 2020, 'cited_by_count': 599}, {'year': 2019, 'cited_by_count': 540}, {'year': 2018, 'cited_by_count': 467}, {'year': 2017, 'cited_by_count': 318}, {'year': 2016, 'cited_by_count': 13}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 2}], 'updated_date': '2024-09-18T23:30:46.468108', 'created_date': '2016-10-14'}