Title: Linear Schiff-base fluorescence probe with aggregation-induced emission characteristics for Al3+ detection and its application in live cell imaging
Abstract: A simple Schiff-base derivative with salicylaldehyde moieties as fluorescent probe 1 was reported by aggregation-induced emission (AIE) characterization for the detection of metal ions. Spectral analysis revealed that probe 1 was highly selective and sensitive to Al3+. The probe 1 was also subject to minimal interference from other common competitive metal ions. The detection limit of Al3+ was 0.4 μM, which is considerably lower than the World Health Organization standard (7.41 μM), and the acceptable level of Al3+ (1.85 μM) in drinking water. The Job's plot and the results of 1H-NMR and FT-IR analyses indicated that the binding stoichiometry ratio of probe 1 to Al3+ was 1:2. Probe 1 demonstrated a fluorescence-enhanced response upon binding with Al3+ based on AIE characterization. This response was due to the restricted molecular rotation and increased rigidity of the molecular assembly. Probe 1 exhibited good biocompatibility, and Al3+ was detected in live cells. Therefore, probe 1 is a promising fluorescence probe for Al3+ detection in the environment.
Publication Year: 2016
Publication Date: 2016-10-09
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 56
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