Publication Information

{'id': 'https://openalex.org/W2519731031', 'doi': 'https://doi.org/10.3999/jscpt.15.567', 'title': 'Efficacy of nadolol (PS-527) in treatment of angina pectoris. A multicenter double-blind group-comparison study.', 'display_name': 'Efficacy of nadolol (PS-527) in treatment of angina pectoris. A multicenter double-blind group-comparison study.', 'publication_year': 1984, 'publication_date': '1984-01-01', 'ids': {'openalex': 'https://openalex.org/W2519731031', 'doi': 'https://doi.org/10.3999/jscpt.15.567', 'mag': '2519731031'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3999/jscpt.15.567', 'pdf_url': 'https://www.jstage.jst.go.jp/article/jscpt1970/15/4/15_4_567/_pdf', 'source': {'id': 'https://openalex.org/S2764687680', 'display_name': 'Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics', 'issn_l': '0388-1601', 'issn': ['0388-1601', '1882-8272'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.jstage.jst.go.jp/article/jscpt1970/15/4/15_4_567/_pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5064703883', 'display_name': 'Hirokazu Niitani', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I119182057', 'display_name': 'Showa University', 'ror': 'https://ror.org/04mzk4q39', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I119182057']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hirokazu NIITANI', 'raw_affiliation_strings': ['The Third Department of Internal Medicine, School of Medicine, Showa University'], 'affiliations': [{'raw_affiliation_string': 'The Third Department of Internal Medicine, School of Medicine, Showa University', 'institution_ids': ['https://openalex.org/I119182057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068631788', 'display_name': 'Fumihide Yoshida', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I119182057', 'display_name': 'Showa University', 'ror': 'https://ror.org/04mzk4q39', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I119182057']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Fumihide YOSHIDA', 'raw_affiliation_strings': ['Department of Internal Medicine, Toyosu Hospital, Showa University'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Toyosu Hospital, Showa University', 'institution_ids': ['https://openalex.org/I119182057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110795015', 'display_name': 'Yasushi Mizuno', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I119806188', 'display_name': 'Kumamoto Gakuen University', 'ror': 'https://ror.org/04jhcmb20', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I119806188']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yasushi MIZUNO', 'raw_affiliation_strings': ['Department of Internal Medicine, School of Medicine, Fujita-Gakuen University'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, School of Medicine, Fujita-Gakuen University', 'institution_ids': ['https://openalex.org/I119806188']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113436740', 'display_name': 'Hisashi Fukuzaki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I65837984', 'display_name': 'Kobe University', 'ror': 'https://ror.org/03tgsfw79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I65837984']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hisashi FUKUZAKI', 'raw_affiliation_strings': ['The First Department of Internal Medicine, School of Medicine, Kobe University'], 'affiliations': [{'raw_affiliation_string': 'The First Department of Internal Medicine, School of Medicine, Kobe University', 'institution_ids': ['https://openalex.org/I65837984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025390571', 'display_name': 'Hisakazu Yasuda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I205349734', 'display_name': 'Hokkaido University', 'ror': 'https://ror.org/02e16g702', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I205349734']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hisakazu YASUDA', 'raw_affiliation_strings': ['Department of Cardiovascular Medicine, School of Medicine, Hokkaido University'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiovascular Medicine, School of Medicine, Hokkaido University', 'institution_ids': ['https://openalex.org/I205349734']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110330256', 'display_name': 'Kizuku Kuramoto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210152580', 'display_name': 'Tokyo Metropolitan Geriatric Hospital', 'ror': 'https://ror.org/04emv5a43', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152580']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kizuku KURAMOTO', 'raw_affiliation_strings': ['Department of Internal Medicine, Tokyo Metropolitan Geriatric Hospital'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Tokyo Metropolitan Geriatric Hospital', 'institution_ids': ['https://openalex.org/I4210152580']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084052988', 'display_name': 'Hironori Toshima', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I105296287', 'display_name': 'Kurume University', 'ror': 'https://ror.org/057xtrt18', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I105296287']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hironori TOSHIMA', 'raw_affiliation_strings': ['The Third Department of Internal Medicine, School of Medicine, Kurume University'], 'affiliations': [{'raw_affiliation_string': 'The Third Department of Internal Medicine, School of Medicine, Kurume University', 'institution_ids': ['https://openalex.org/I105296287']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113964613', 'display_name': 'Kazuhiko Murata', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I165735259', 'display_name': 'Gunma University', 'ror': 'https://ror.org/046fm7598', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I165735259']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuhiko MURATA', 'raw_affiliation_strings': ['The Second Department of Internal Medicine, School of Medicine, Gunma University'], 'affiliations': [{'raw_affiliation_string': 'The Second Department of Internal Medicine, School of Medicine, Gunma University', 'institution_ids': ['https://openalex.org/I165735259']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111574312', 'display_name': 'Akira Sakuma', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I125602781', 'display_name': 'Tokyo Medical and Dental University', 'ror': 'https://ror.org/051k3eh31', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I125602781']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akira SAKUMA', 'raw_affiliation_strings': ['Department of Clinical Pharmacology, Medical Research Institute, Tokyo Medical and Dental University'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacology, Medical Research Institute, Tokyo Medical and Dental University', 'institution_ids': ['https://openalex.org/I125602781']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 8, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 53}, 'biblio': {'volume': '15', 'issue': '4', 'first_page': '567', 'last_page': '583'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13004', 'display_name': 'Vitamin K Research Studies', 'score': 0.8682, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13004', 'display_name': 'Vitamin K Research Studies', 'score': 0.8682, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 0.867, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11460', 'display_name': 'Analytical Methods in Pharmaceuticals', 'score': 0.8607, 'subfield': {'id': 'https://openalex.org/subfields/1602', 'display_name': 'Analytical Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nadolol', 'display_name': 'Nadolol', 'score': 0.9946898}], 'concepts': [{'id': 'https://openalex.org/C2776256041', 'wikidata': 'https://www.wikidata.org/wiki/Q424952', 'display_name': 'Nadolol', 'level': 3, 'score': 0.9946898}, {'id': 'https://openalex.org/C2778151854', 'wikidata': 'https://www.wikidata.org/wiki/Q423364', 'display_name': 'Propranolol', 'level': 2, 'score': 0.9166908}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8057846}, {'id': 'https://openalex.org/C2778425758', 'wikidata': 'https://www.wikidata.org/wiki/Q180762', 'display_name': 'Angina', 'level': 3, 'score': 0.630269}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.53353727}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.5166745}, {'id': 'https://openalex.org/C2777953023', 'wikidata': 'https://www.wikidata.org/wiki/Q1073121', 'display_name': 'Heart rate', 'level': 3, 'score': 0.5103697}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.30640078}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.25215054}, {'id': 'https://openalex.org/C500558357', 'wikidata': 'https://www.wikidata.org/wiki/Q12152', 'display_name': 'Myocardial infarction', 'level': 2, 'score': 0.05569166}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3999/jscpt.15.567', 'pdf_url': 'https://www.jstage.jst.go.jp/article/jscpt1970/15/4/15_4_567/_pdf', 'source': {'id': 'https://openalex.org/S2764687680', 'display_name': 'Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics', 'issn_l': '0388-1601', 'issn': ['0388-1601', '1882-8272'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3999/jscpt.15.567', 'pdf_url': 'https://www.jstage.jst.go.jp/article/jscpt1970/15/4/15_4_567/_pdf', 'source': {'id': 'https://openalex.org/S2764687680', 'display_name': 'Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics', 'issn_l': '0388-1601', 'issn': ['0388-1601', '1882-8272'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.87}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 11, 'referenced_works': ['https://openalex.org/W1993379021', 'https://openalex.org/W2009516197', 'https://openalex.org/W2020133006', 'https://openalex.org/W2021168120', 'https://openalex.org/W2034130688', 'https://openalex.org/W2038268736', 'https://openalex.org/W2062562410', 'https://openalex.org/W2089067361', 'https://openalex.org/W2183851561', 'https://openalex.org/W2322681239', 'https://openalex.org/W2397057878'], 'related_works': ['https://openalex.org/W42318249', 'https://openalex.org/W2410092555', 'https://openalex.org/W2369397604', 'https://openalex.org/W2274904533', 'https://openalex.org/W2185880733', 'https://openalex.org/W2172058999', 'https://openalex.org/W2140672730', 'https://openalex.org/W2061655595', 'https://openalex.org/W1997921347', 'https://openalex.org/W1987784075'], 'abstract_inverted_index': {'The': [0, 12, 27, 105], 'anti-anginal': [1], 'effect': [2, 68], 'of': [3, 9, 43, 54, 74, 77, 82, 102, 160, 191, 195, 229, 233, 255, 258, 263, 269, 277, 300, 307, 332], 'nadolol': [4, 96, 110, 139, 165, 184, 238, 285, 320], 'was': [5, 15, 36, 48, 69, 84, 90, 112, 117, 147, 175, 218, 242, 295], 'compared': [6], 'with': [7, 23, 32, 199, 334], 'that': [8, 303, 319], 'propranolol': [10, 47, 98, 122, 144, 214, 292], '.': [11], 'present': [13], 'study': [14], 'carried': [16], 'out': [17], 'as': [18], 'a': [19, 39, 51, 308, 322], 'multicenter,': [20], 'double-blind': [21], 'group-comparison,': [22], 'the': [24, 72, 79, 95, 109, 121, 125, 129, 131, 158, 183, 189, 192, 200, 204, 213, 222, 227, 230, 237, 246, 253, 261, 264, 267, 278, 284, 291, 301, 304, 329], 'following': [25], 'results.1.': [26], 'subjects': [28], 'were': [29, 135, 163, 280], 'primarily': [30], 'patients': [31, 270, 333], 'effort': [33, 161], 'angina.': [34], 'Nadolol': [35], 'administered': [37, 49], 'in': [38, 50, 58, 100, 108, 120, 181, 197, 212, 221, 236, 244], 'single': [40, 309], 'daily': [41, 52, 80, 310], 'dose': [42, 311], '30': [44, 55], 'mg,': [45], 'while': [46, 115], 'dosage': [53, 81], 'mg': [56], 'given': [57], '3': [59], 'divided': [60], 'doses,': [61], 'for': [62, 138, 143, 209, 283, 290, 328], '4': [63], 'weeks': [64, 76, 257], 'each.': [65], 'When': [66], 'no': [67, 91, 148], 'noted': [70], 'by': [71, 128], 'end': [73, 190, 228, 254], '2': [75, 256], 'treatment,': [78, 234], 'each': [83], 'increased': [85], 'to': [86, 167, 170, 177, 203], '60': [87], 'mg.2.': [88], 'There': [89, 146], 'significant': [92, 149, 216, 240], 'difference': [93, 150, 294], 'between': [94, 151], 'and': [97, 140, 185, 248, 287], 'groups': [99, 187], 'terms': [101], 'clinical': [103, 330], 'usefulness.': [104], 'usefulness': [106], 'rate': [107, 174, 201], 'group': [111, 215, 239, 286], '80.0%': [113], '(28/35),': [114], 'it': [116, 316], '64.9%': [118], '(24/37)': [119], 'group.3.': [123], 'In': [124], 'evaluation': [126], 'performed': [127], 'physician-in-charge,': [130], 'global': [132], 'improvement': [133], 'rates': [134], '77.1%': [136], '(27/35)': [137], '62.2%': [141], '(23/37)': [142], 'groups.': [145], 'these': [152, 313], 'two': [153], 'rates.': [154], 'However,': [155], 'when': [156], 'only': [157, 220], 'cases': [159], 'angina': [162, 335], 'considered,': [164], 'appeared': [166], 'be': [168, 178], 'superior': [169], 'propra': [171], 'nolol.4.': [172], 'Heart': [173], 'found': [176], 'significantly': [179], 'decreased': [180], 'both': [182, 245], 'prop-ranolol': [186], 'from': [188], 'first': [193], 'week': [194, 232], 'treatment': [196, 206, 331], 'comparison': [198], 'prior': [202], 'drug': [205, 265, 279, 325], 'period.': [207], 'As': [208], 'blood': [210, 224, 250], 'pressure,': [211], 'decrease': [217, 241], 'seen': [219, 243], 'systolic': [223, 247], 'pressure': [225], 'at': [226, 252], '4th': [231], 'whereas': [235], 'diastolic': [249], 'pressures': [251], 'treatment.5.': [259], 'Concerning': [260], 'safety': [262], 'regimen,': [266], 'percentages': [268], 'not': [271, 296], 'show': [272], 'ing': [273], 'any': [274], 'side': [275], 'effects': [276], '86.0%': [281], '(43/50)': [282], '92.3%': [288], '(48/52)': [289], 'group.This': [293], 'statistically': [297], 'significant.In': [298], 'consideration': [299], 'fact': [302], 'nodolol': [305], 'regimen': [306], 'gave': [312], 'good': [314], 'results,': [315], 'is': [317, 321], 'concluded': [318], 'more': [323], 'useful': [324], 'than': [326], 'proprano-lol': [327], 'pectoris.': [336]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2519731031', 'counts_by_year': [], 'updated_date': '2024-12-13T21:49:15.415775', 'created_date': '2016-09-23'}