Title: Effectiveness of a culturally attuned Internet-based depression prevention program for Chinese adolescents: A randomized controlled trial
Abstract: Depression and AnxietyVolume 33, Issue 12 p. 1123-1131 Research Article Effectiveness of a culturally attuned Internet-based depression prevention program for Chinese adolescents: A randomized controlled trial Patrick Ip M.B.B.S., M.P.H., Corresponding Author Patrick Ip M.B.B.S., M.P.H. [email protected][email protected] Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Correspondence Patrick Ip, 1/F, New Clinical Building, Queen Mary Hospital, Pokfulam, Hong Kong; Ko Ling Chan, 5/F, The Jockey Club Tower, Centennial Campus, The University of Hong Kong, Hong Kong. Email: [email protected]; [email protected] for more papers by this authorDavid Chim D.O., David Chim D.O. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorKo Ling Chan Ph.D., Ko Ling Chan Ph.D. Department of Social Work and Social Administration, Faculty of Social Sciences, The University of Hong Kong, Hong KongSearch for more papers by this authorTim M.H. Li Ph.D., Tim M.H. Li Ph.D. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorFrederick Ka Wing Ho P.G.D.E., Frederick Ka Wing Ho P.G.D.E. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorBenjamin W. Van Voorhees M.D., Benjamin W. Van Voorhees M.D. Department of Pediatrics, University of Illinois at Chicago, Chicago, IL, USASearch for more papers by this authorAgnes Tiwari Ph.D., Agnes Tiwari Ph.D. School of Nursing, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorAnita Tsang M.B.B.S., Anita Tsang M.B.B.S. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorCharlie Wai Leung Chan M.A., Charlie Wai Leung Chan M.A. Caritas Youth and Community Service, Aberdeen, Hong KongSearch for more papers by this authorMatthew Ho Ph.D., Matthew Ho Ph.D. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorWinnie Tso M.B.B.S., Winnie Tso M.B.B.S. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorWilfred Hing Sang Wong M.Med.Sc., Wilfred Hing Sang Wong M.Med.Sc. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this author Patrick Ip M.B.B.S., M.P.H., Corresponding Author Patrick Ip M.B.B.S., M.P.H. [email protected][email protected] Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Correspondence Patrick Ip, 1/F, New Clinical Building, Queen Mary Hospital, Pokfulam, Hong Kong; Ko Ling Chan, 5/F, The Jockey Club Tower, Centennial Campus, The University of Hong Kong, Hong Kong. Email: [email protected]; [email protected] for more papers by this authorDavid Chim D.O., David Chim D.O. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorKo Ling Chan Ph.D., Ko Ling Chan Ph.D. Department of Social Work and Social Administration, Faculty of Social Sciences, The University of Hong Kong, Hong KongSearch for more papers by this authorTim M.H. Li Ph.D., Tim M.H. Li Ph.D. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorFrederick Ka Wing Ho P.G.D.E., Frederick Ka Wing Ho P.G.D.E. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorBenjamin W. Van Voorhees M.D., Benjamin W. Van Voorhees M.D. Department of Pediatrics, University of Illinois at Chicago, Chicago, IL, USASearch for more papers by this authorAgnes Tiwari Ph.D., Agnes Tiwari Ph.D. School of Nursing, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorAnita Tsang M.B.B.S., Anita Tsang M.B.B.S. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorCharlie Wai Leung Chan M.A., Charlie Wai Leung Chan M.A. Caritas Youth and Community Service, Aberdeen, Hong KongSearch for more papers by this authorMatthew Ho Ph.D., Matthew Ho Ph.D. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorWinnie Tso M.B.B.S., Winnie Tso M.B.B.S. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this authorWilfred Hing Sang Wong M.Med.Sc., Wilfred Hing Sang Wong M.Med.Sc. Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong KongSearch for more papers by this author First published: 13 September 2016 https://doi.org/10.1002/da.22554Citations: 35 Contract grant sponsor: Lotteries Fund for Pilot Cyber Youth Outreaching Project. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Background Depression prevention among adolescents is crucial for reducing the global disease burden. Internet-based depression prevention approaches are found to be effective but they were mostly evaluated in a Western context. Grasping the Opportunity is a Chinese Internet intervention, which was translated and modified from CATCH-IT developed in the West. We aimed to evaluate the effectiveness of Grasp the Opportunity in reducing depressive symptoms in Chinese adolescents. Methods In this randomized controlled trial, Chinese adolescents aged 13 to 17 years with mild-to-moderate depressive symptoms were recruited from three secondary schools in Hong Kong. The participants (n = 257) were randomly assigned to receive either intervention or attention control. The primary outcome was the improvement in depressive symptoms according to the revised Center for Epidemiologic Studies Depression Scale (CESD-R) at the 12-month follow-up. Analyses were performed using intention to treat (ITT). Results The participants were randomly assigned to receive the intervention (n = 130) or attention control (n = 127). Follow-up data were obtained from 250 (97%) participants. Only 26 (10%) participants completed the intervention. Compared to the attention control, Grasp the Opportunity led to reductions in depressive symptoms at the 12-month follow-up with a medium effect size using ITT analysis (mean difference 2.6, 95% CI 0.59–5.55, effect size d = 0.36). Conclusions Grasp the Opportunity is effective in reducing depressive symptoms in Chinese adolescents over a long follow-up period. Poor completion rate is the major challenge in the study. Citing Literature Volume33, Issue12FOCUS ON TREATMENTDecember 2016Pages 1123-1131 RelatedInformation