Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2518857381', 'doi': 'https://doi.org/10.1097/iae.0000000000001279', 'title': 'REGRESSION OF TYPE 2 NEOVASCULARIZATION INTO A TYPE 1 PATTERN AFTER INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION', 'display_name': 'REGRESSION OF TYPE 2 NEOVASCULARIZATION INTO A TYPE 1 PATTERN AFTER INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION', 'publication_year': 2016, 'publication_date': '2016-09-14', 'ids': {'openalex': 'https://openalex.org/W2518857381', 'doi': 'https://doi.org/10.1097/iae.0000000000001279', 'mag': '2518857381', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27627752'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/iae.0000000000001279', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S19572933', 'display_name': 'Retina', 'issn_l': '0275-004X', 'issn': ['0275-004X', '1539-2864'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5008720591', 'display_name': 'J. Fernando Arévalo', 'orcid': 'https://orcid.org/0000-0002-2963-2541'}, 'institutions': [{'id': 'https://openalex.org/I150569930', 'display_name': 'Bayer (United States)', 'ror': 'https://ror.org/034ffbg36', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I150569930', 'https://openalex.org/I67348948']}, {'id': 'https://openalex.org/I4210087383', 'display_name': 'Vitreous Retina Macula Consultants of New York', 'ror': 'https://ror.org/0040x4m25', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087383']}, {'id': 'https://openalex.org/I2800970057', 'display_name': 'Manhattan Eye, Ear and Throat Hospital', 'ror': 'https://ror.org/008a4de11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800970057']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rosa Dolz-Marco', 'raw_affiliation_strings': ['D. Sarraf: Research grants from Genentech, Regeneron and Optovue. Consultant to Genentech and Optovue; K. B. Freund: Consultant to Genentech, Optos, Optovue, Heidelberg Engineering, and Bayer HealthCare.; N. Phasukkijwatana: None; R. Dolz-Marco: Research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea; Reprint requests: K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022; The funding organizations had no role in the design or conduct of this research. Contributions of authors: design of the study (K.B.F.), conduct of the study (D.S., K.B.F., N.P., R.D.-M.), collection of the data (D.S., K.B.F., N.P., R.D.-M.), management of the data (N.P., R.D.-M.), analysis of the data (K.B.F., R.D.-M.), interpretation of the data (K.B.F., R.D.-M.), preparation of the manuscript (R.D.-M.), review of the manuscript (D.S., K.B.F., N.P., R.D.-M.), and approval of the manuscript (D.S., K.B.F., N.P., R.D.-M.).; This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, NY, and The Macula Foundation Inc, New York, NY.; e-mail: [email\xa0protected]; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.; ‖Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California'], 'affiliations': [{'raw_affiliation_string': 'D. Sarraf: Research grants from Genentech, Regeneron and Optovue. Consultant to Genentech and Optovue; K. B. Freund: Consultant to Genentech, Optos, Optovue, Heidelberg Engineering, and Bayer HealthCare.; N. Phasukkijwatana: None; R. Dolz-Marco: Research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea; Reprint requests: K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022; The funding organizations had no role in the design or conduct of this research. Contributions of authors: design of the study (K.B.F.), conduct of the study (D.S., K.B.F., N.P., R.D.-M.), collection of the data (D.S., K.B.F., N.P., R.D.-M.), management of the data (N.P., R.D.-M.), analysis of the data (K.B.F., R.D.-M.), interpretation of the data (K.B.F., R.D.-M.), preparation of the manuscript (R.D.-M.), review of the manuscript (D.S., K.B.F., N.P., R.D.-M.), and approval of the manuscript (D.S., K.B.F., N.P., R.D.-M.).; This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, NY, and The Macula Foundation Inc, New York, NY.; e-mail: [email\xa0protected]; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.; ‖Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California', 'institution_ids': ['https://openalex.org/I150569930', 'https://openalex.org/I4210087383', 'https://openalex.org/I2800970057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013374512', 'display_name': 'Nopasak Phasukkijwatana', 'orcid': 'https://orcid.org/0000-0002-2317-771X'}, 'institutions': [{'id': 'https://openalex.org/I150569930', 'display_name': 'Bayer (United States)', 'ror': 'https://ror.org/034ffbg36', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I150569930', 'https://openalex.org/I67348948']}, {'id': 'https://openalex.org/I4210087383', 'display_name': 'Vitreous Retina Macula Consultants of New York', 'ror': 'https://ror.org/0040x4m25', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087383']}, {'id': 'https://openalex.org/I2800970057', 'display_name': 'Manhattan Eye, Ear and Throat Hospital', 'ror': 'https://ror.org/008a4de11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800970057']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nopasak Phasukkijwatana', 'raw_affiliation_strings': ['D. Sarraf: Research grants from Genentech, Regeneron and Optovue. Consultant to Genentech and Optovue; K. B. Freund: Consultant to Genentech, Optos, Optovue, Heidelberg Engineering, and Bayer HealthCare.; N. Phasukkijwatana: None; R. Dolz-Marco: Research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea; Reprint requests: K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022; The funding organizations had no role in the design or conduct of this research. Contributions of authors: design of the study (K.B.F.), conduct of the study (D.S., K.B.F., N.P., R.D.-M.), collection of the data (D.S., K.B.F., N.P., R.D.-M.), management of the data (N.P., R.D.-M.), analysis of the data (K.B.F., R.D.-M.), interpretation of the data (K.B.F., R.D.-M.), preparation of the manuscript (R.D.-M.), review of the manuscript (D.S., K.B.F., N.P., R.D.-M.), and approval of the manuscript (D.S., K.B.F., N.P., R.D.-M.).; This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, NY, and The Macula Foundation Inc, New York, NY.; e-mail: [email\xa0protected]; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.; ‖Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California'], 'affiliations': [{'raw_affiliation_string': 'D. Sarraf: Research grants from Genentech, Regeneron and Optovue. Consultant to Genentech and Optovue; K. B. Freund: Consultant to Genentech, Optos, Optovue, Heidelberg Engineering, and Bayer HealthCare.; N. Phasukkijwatana: None; R. Dolz-Marco: Research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea; Reprint requests: K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022; The funding organizations had no role in the design or conduct of this research. Contributions of authors: design of the study (K.B.F.), conduct of the study (D.S., K.B.F., N.P., R.D.-M.), collection of the data (D.S., K.B.F., N.P., R.D.-M.), management of the data (N.P., R.D.-M.), analysis of the data (K.B.F., R.D.-M.), interpretation of the data (K.B.F., R.D.-M.), preparation of the manuscript (R.D.-M.), review of the manuscript (D.S., K.B.F., N.P., R.D.-M.), and approval of the manuscript (D.S., K.B.F., N.P., R.D.-M.).; This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, NY, and The Macula Foundation Inc, New York, NY.; e-mail: [email\xa0protected]; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.; ‖Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California', 'institution_ids': ['https://openalex.org/I150569930', 'https://openalex.org/I4210087383', 'https://openalex.org/I2800970057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102861829', 'display_name': 'David Sarraf', 'orcid': 'https://orcid.org/0000-0001-9001-0277'}, 'institutions': [{'id': 'https://openalex.org/I2800970057', 'display_name': 'Manhattan Eye, Ear and Throat Hospital', 'ror': 'https://ror.org/008a4de11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800970057']}, {'id': 'https://openalex.org/I150569930', 'display_name': 'Bayer (United States)', 'ror': 'https://ror.org/034ffbg36', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I150569930', 'https://openalex.org/I67348948']}, {'id': 'https://openalex.org/I4210087383', 'display_name': 'Vitreous Retina Macula Consultants of New York', 'ror': 'https://ror.org/0040x4m25', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087383']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David Sarraf', 'raw_affiliation_strings': ['D. Sarraf: Research grants from Genentech, Regeneron and Optovue. Consultant to Genentech and Optovue; K. B. Freund: Consultant to Genentech, Optos, Optovue, Heidelberg Engineering, and Bayer HealthCare.; N. Phasukkijwatana: None; R. Dolz-Marco: Research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea; Reprint requests: K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022; The funding organizations had no role in the design or conduct of this research. Contributions of authors: design of the study (K.B.F.), conduct of the study (D.S., K.B.F., N.P., R.D.-M.), collection of the data (D.S., K.B.F., N.P., R.D.-M.), management of the data (N.P., R.D.-M.), analysis of the data (K.B.F., R.D.-M.), interpretation of the data (K.B.F., R.D.-M.), preparation of the manuscript (R.D.-M.), review of the manuscript (D.S., K.B.F., N.P., R.D.-M.), and approval of the manuscript (D.S., K.B.F., N.P., R.D.-M.).; This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, NY, and The Macula Foundation Inc, New York, NY.; e-mail: [email\xa0protected]; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.; ‖Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California'], 'affiliations': [{'raw_affiliation_string': 'D. Sarraf: Research grants from Genentech, Regeneron and Optovue. Consultant to Genentech and Optovue; K. B. Freund: Consultant to Genentech, Optos, Optovue, Heidelberg Engineering, and Bayer HealthCare.; N. Phasukkijwatana: None; R. Dolz-Marco: Research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea; Reprint requests: K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022; The funding organizations had no role in the design or conduct of this research. Contributions of authors: design of the study (K.B.F.), conduct of the study (D.S., K.B.F., N.P., R.D.-M.), collection of the data (D.S., K.B.F., N.P., R.D.-M.), management of the data (N.P., R.D.-M.), analysis of the data (K.B.F., R.D.-M.), interpretation of the data (K.B.F., R.D.-M.), preparation of the manuscript (R.D.-M.), review of the manuscript (D.S., K.B.F., N.P., R.D.-M.), and approval of the manuscript (D.S., K.B.F., N.P., R.D.-M.).; This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, NY, and The Macula Foundation Inc, New York, NY.; e-mail: [email\xa0protected]; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.; ‖Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California', 'institution_ids': ['https://openalex.org/I2800970057', 'https://openalex.org/I150569930', 'https://openalex.org/I4210087383']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5019296720', 'display_name': 'K. Bailey Freund', 'orcid': 'https://orcid.org/0000-0002-7888-9773'}, 'institutions': [{'id': 'https://openalex.org/I2800970057', 'display_name': 'Manhattan Eye, Ear and Throat Hospital', 'ror': 'https://ror.org/008a4de11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800970057']}, {'id': 'https://openalex.org/I150569930', 'display_name': 'Bayer (United States)', 'ror': 'https://ror.org/034ffbg36', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I150569930', 'https://openalex.org/I67348948']}, {'id': 'https://openalex.org/I4210087383', 'display_name': 'Vitreous Retina Macula Consultants of New York', 'ror': 'https://ror.org/0040x4m25', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087383']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'K. Bailey Freund', 'raw_affiliation_strings': ['D. Sarraf: Research grants from Genentech, Regeneron and Optovue. Consultant to Genentech and Optovue; K. B. Freund: Consultant to Genentech, Optos, Optovue, Heidelberg Engineering, and Bayer HealthCare.; N. Phasukkijwatana: None; R. Dolz-Marco: Research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea; Reprint requests: K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022; The funding organizations had no role in the design or conduct of this research. Contributions of authors: design of the study (K.B.F.), conduct of the study (D.S., K.B.F., N.P., R.D.-M.), collection of the data (D.S., K.B.F., N.P., R.D.-M.), management of the data (N.P., R.D.-M.), analysis of the data (K.B.F., R.D.-M.), interpretation of the data (K.B.F., R.D.-M.), preparation of the manuscript (R.D.-M.), review of the manuscript (D.S., K.B.F., N.P., R.D.-M.), and approval of the manuscript (D.S., K.B.F., N.P., R.D.-M.).; This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, NY, and The Macula Foundation Inc, New York, NY.; e-mail: [email\xa0protected]; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.; ‖Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California'], 'affiliations': [{'raw_affiliation_string': 'D. Sarraf: Research grants from Genentech, Regeneron and Optovue. Consultant to Genentech and Optovue; K. B. Freund: Consultant to Genentech, Optos, Optovue, Heidelberg Engineering, and Bayer HealthCare.; N. Phasukkijwatana: None; R. Dolz-Marco: Research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea; Reprint requests: K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022; The funding organizations had no role in the design or conduct of this research. Contributions of authors: design of the study (K.B.F.), conduct of the study (D.S., K.B.F., N.P., R.D.-M.), collection of the data (D.S., K.B.F., N.P., R.D.-M.), management of the data (N.P., R.D.-M.), analysis of the data (K.B.F., R.D.-M.), interpretation of the data (K.B.F., R.D.-M.), preparation of the manuscript (R.D.-M.), review of the manuscript (D.S., K.B.F., N.P., R.D.-M.), and approval of the manuscript (D.S., K.B.F., N.P., R.D.-M.).; This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, NY, and The Macula Foundation Inc, New York, NY.; e-mail: [email\xa0protected]; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.; ‖Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California', 'institution_ids': ['https://openalex.org/I2800970057', 'https://openalex.org/I150569930', 'https://openalex.org/I4210087383']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.842, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 31, 'citation_normalized_percentile': {'value': 0.999866, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '37', 'issue': '2', 'first_page': '222', 'last_page': '233'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10170', 'display_name': 'Age-Related Macular Degeneration Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10170', 'display_name': 'Age-Related Macular Degeneration Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11438', 'display_name': 'Detection and Management of Retinal Diseases', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12599', 'display_name': 'Ocular Manifestations of COVID-19', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/vascular-endothelial-growth-factor', 'display_name': 'Vascular Endothelial Growth Factor', 'score': 0.572819}, {'id': 'https://openalex.org/keywords/macular-degeneration', 'display_name': 'Macular Degeneration', 'score': 0.55628}, {'id': 'https://openalex.org/keywords/fundus-photography', 'display_name': 'Fundus photography', 'score': 0.53385884}, {'id': 'https://openalex.org/keywords/retinal-artery-occlusion', 'display_name': 'Retinal Artery Occlusion', 'score': 0.529403}, {'id': 'https://openalex.org/keywords/fundus', 'display_name': 'Fundus (uterus)', 'score': 0.52855504}, {'id': 'https://openalex.org/keywords/intravitreal-injection', 'display_name': 'Intravitreal Injection', 'score': 0.516339}, {'id': 'https://openalex.org/keywords/image-analysis', 'display_name': 'Image Analysis', 'score': 0.502491}], 'concepts': [{'id': 'https://openalex.org/C2776403814', 'wikidata': 'https://www.wikidata.org/wiki/Q27429789', 'display_name': 'Macular degeneration', 'level': 2, 'score': 0.7839503}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7622013}, {'id': 'https://openalex.org/C118487528', 'wikidata': 'https://www.wikidata.org/wiki/Q161437', 'display_name': 'Ophthalmology', 'level': 1, 'score': 0.73800874}, {'id': 'https://openalex.org/C2781359195', 'wikidata': 'https://www.wikidata.org/wiki/Q5105209', 'display_name': 'Choroidal neovascularization', 'level': 3, 'score': 0.65077746}, {'id': 'https://openalex.org/C2778024200', 'wikidata': 'https://www.wikidata.org/wiki/Q2346242', 'display_name': 'Retinal pigment epithelium', 'level': 3, 'score': 0.6248631}, {'id': 'https://openalex.org/C2780248432', 'wikidata': 'https://www.wikidata.org/wiki/Q1434206', 'display_name': 'Fluorescein angiography', 'level': 3, 'score': 0.5673262}, {'id': 'https://openalex.org/C2778257484', 'wikidata': 'https://www.wikidata.org/wiki/Q555066', 'display_name': 'Visual acuity', 'level': 2, 'score': 0.55670035}, {'id': 'https://openalex.org/C2778271429', 'wikidata': 'https://www.wikidata.org/wiki/Q1281049', 'display_name': 'Neovascularization', 'level': 3, 'score': 0.5475619}, {'id': 'https://openalex.org/C2776474195', 'wikidata': 'https://www.wikidata.org/wiki/Q1144413', 'display_name': 'Fundus photography', 'level': 4, 'score': 0.53385884}, {'id': 'https://openalex.org/C2776391266', 'wikidata': 'https://www.wikidata.org/wiki/Q9612', 'display_name': 'Fundus (uterus)', 'level': 2, 'score': 0.52855504}, {'id': 'https://openalex.org/C2781100027', 'wikidata': 'https://www.wikidata.org/wiki/Q414270', 'display_name': 'Ranibizumab', 'level': 4, 'score': 0.43165016}, {'id': 'https://openalex.org/C2778818243', 'wikidata': 'https://www.wikidata.org/wiki/Q899552', 'display_name': 'Optical coherence tomography', 'level': 2, 'score': 0.41804227}, {'id': 'https://openalex.org/C2780827179', 'wikidata': 'https://www.wikidata.org/wiki/Q422001', 'display_name': 'Retinal', 'level': 2, 'score': 0.34887367}, {'id': 'https://openalex.org/C2777802072', 'wikidata': 'https://www.wikidata.org/wiki/Q413299', 'display_name': 'Bevacizumab', 'level': 3, 'score': 0.24580494}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.21381146}, {'id': 'https://openalex.org/C2780394083', 'wikidata': 'https://www.wikidata.org/wiki/Q539568', 'display_name': 'Angiogenesis', 'level': 2, 'score': 0.091683745}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.087667674}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D020533', 'descriptor_name': 'Angiogenesis Inhibitors', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D015861', 'descriptor_name': 'Retinal Neovascularization', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D057135', 'descriptor_name': 'Wet Macular Degeneration', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020533', 'descriptor_name': 'Angiogenesis Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003430', 'descriptor_name': 'Cross-Sectional Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005451', 'descriptor_name': 'Fluorescein Angiography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058449', 'descriptor_name': 'Intravitreal Injections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015861', 'descriptor_name': 'Retinal Neovascularization', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D015861', 'descriptor_name': 'Retinal Neovascularization', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D015861', 'descriptor_name': 'Retinal Neovascularization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055213', 'descriptor_name': 'Retinal Pigment Epithelium', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D055213', 'descriptor_name': 'Retinal Pigment Epithelium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D041623', 'descriptor_name': 'Tomography, Optical Coherence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D042461', 'descriptor_name': 'Vascular Endothelial Growth Factor A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D042461', 'descriptor_name': 'Vascular Endothelial Growth Factor A', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D014792', 'descriptor_name': 'Visual Acuity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057135', 'descriptor_name': 'Wet Macular Degeneration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057135', 'descriptor_name': 'Wet Macular Degeneration', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/iae.0000000000001279', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S19572933', 'display_name': 'Retina', 'issn_l': '0275-004X', 'issn': ['0275-004X', '1539-2864'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27627752', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.54, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 26, 'referenced_works': ['https://openalex.org/W1601975653', 'https://openalex.org/W1635236470', 'https://openalex.org/W1817671088', 'https://openalex.org/W1922180152', 'https://openalex.org/W1983443598', 'https://openalex.org/W2020230547', 'https://openalex.org/W2023057734', 'https://openalex.org/W2056293400', 'https://openalex.org/W2058266372', 'https://openalex.org/W2089172396', 'https://openalex.org/W2089603816', 'https://openalex.org/W2111105229', 'https://openalex.org/W2117109937', 'https://openalex.org/W2122974013', 'https://openalex.org/W2160226180', 'https://openalex.org/W2164200654', 'https://openalex.org/W2169961704', 'https://openalex.org/W2218141388', 'https://openalex.org/W2264624788', 'https://openalex.org/W2316418129', 'https://openalex.org/W2322602077', 'https://openalex.org/W2325901584', 'https://openalex.org/W2328055011', 'https://openalex.org/W2328962274', 'https://openalex.org/W2472181847', 'https://openalex.org/W4242385022'], 'related_works': ['https://openalex.org/W88626775', 'https://openalex.org/W875204454', 'https://openalex.org/W3029611346', 'https://openalex.org/W2801474660', 'https://openalex.org/W2531729507', 'https://openalex.org/W2366632612', 'https://openalex.org/W2262794518', 'https://openalex.org/W2168598279', 'https://openalex.org/W2030316160', 'https://openalex.org/W2019372170'], 'abstract_inverted_index': {'To': [0], 'study': [1], 'eyes': [2, 125, 207, 305, 336], 'with': [3, 30, 132, 245, 306, 312, 346], 'Type': [4, 22, 45, 50, 135, 237, 242, 280, 308, 332, 347], '2': [5, 46, 136, 238, 281, 309, 348], '(subretinal)': [6], 'neovascularization': [7, 47, 137], '(NV)': [8], 'secondary': [9, 138], 'to': [10, 139, 170, 289, 294, 338, 351], 'neovascular': [11, 193, 322], 'age-related': [12], 'macular': [13], 'degeneration': [14], '(nAMD)': [15], 'that': [16], 'shows': [17], 'lesion': [18, 194], 'regression': [19, 43, 234, 301], 'into': [20, 48, 240], 'a': [21, 49, 188, 214, 241, 331], '1': [23, 51, 243, 333], '(subretinal': [24], 'pigment': [25, 57, 189, 250, 276, 328], 'epithelium)': [26], 'pattern': [27, 52, 244, 302], 'after': [28, 53, 266], 'treatment': [29], 'intravitreal': [31, 313], 'anti-vascular': [32, 314], 'endothelial': [33, 315], 'growth': [34, 316], 'factor': [35, 317], '(VEGF)': [36], 'therapy.Retrospective': [37], 'consecutive': [38], 'case': [39], 'series.': [40], 'Patients': [41], 'showing': [42], 'of': [44, 66, 73, 126, 220, 235], 'envelopment': [54, 246], 'by': [55, 247, 326], 'retinal': [56, 249, 275, 327, 354], 'epithelium': [58, 277, 329], 'were': [59, 110, 121, 141], 'included': [60], 'in': [61, 157, 195, 205, 218, 285, 304, 319], 'this': [62], 'analysis.': [63], 'A': [64, 198], 'review': [65], 'the': [67, 192, 221, 232, 236, 248, 321], 'clinical': [68], 'records': [69], 'and': [70, 83, 103, 112, 167, 184, 254], 'multimodal': [71], 'imaging': [72], 'these': [74], 'cases': [75], 'was': [76, 146, 160, 201], 'performed': [77], 'at': [78, 165, 175, 208], 'baseline,': [79, 181], '1,': [80], '3,': [81], '6,': [82], '12': [84], 'months.': [85], 'Demographic': [86], 'data,': [87], 'best-corrected': [88, 153], 'visual': [89, 154, 291, 341], 'acuity': [90, 155], '(BCVA),': [91], 'color': [92, 182], 'fundus': [93, 95, 185, 216], 'photography,': [94], 'autofluorescence': [96, 186], '(FAF),': [97], 'fluorescein': [98], 'angiography,': [99], 'near-infrared': [100], 'reflectance': [101], '(NIR),': [102], 'structural': [104, 225], 'spectral-domain': [105, 226], 'optical': [106, 116, 227, 256], 'coherence': [107, 117, 228, 257], 'tomography': [108, 118, 229, 258], '(SD-OCT)': [109], 'reviewed': [111], 'analyzed.': [113], 'When': [114], 'available,': [115], 'angiography': [119, 259], 'images': [120], 'analyzed': [122], 'as': [123], 'well.Ten': [124], '9': [127, 219], 'patients': [128], '(6': [129], 'males)': [130], 'diagnosed': [131], 'treatment-naive': [133], 'pure': [134], 'nAMD': [140], 'included.': [142], 'The': [143], 'mean': [144], 'age': [145], '80.7': [147], 'years': [148], '(SD': [149], '±': [150, 162, 172], '4.30).': [151], 'Mean': [152], 'expressed': [156], 'logMAR': [158], '(Snellen)': [159], '0.45': [161], '0.20': [163], '(20/55)': [164], 'baseline': [166, 261], 'significantly': [168], 'improved': [169], '0.22': [171], '0.13': [173], '(20/32)': [174], '3-month': [176, 209], 'follow-up': [177], '(P-value:': [178], '0.007).': [179], 'At': [180], 'photographs': [183, 212], 'showed': [187, 213, 231, 260], 'ring': [190, 200], 'around': [191], '6': [196], 'eyes.': [197, 223], 'hyperreflective': [199, 274], 'visible': [202], 'on': [203], 'NIR': [204], 'all': [206], 'follow-up.': [210], 'Color': [211], 'tessellated': [215], 'appearance': [217], '10': [222], 'Serial': [224], 'scans': [230], 'gradual': [233], 'lesions': [239, 282, 310, 349], 'epithelium.': [251], 'En': [252], 'face': [253], 'cross-sectional': [255], 'subretinal': [262, 295], 'flow': [263, 270], 'patterns': [264], 'which,': [265], 'treatment,': [267], 'exhibited': [268], 'reduced': [269, 352], 'beneath': [271], 'an': [272, 299], 'intact': [273], '(RPE)': [278], 'band.Pure': [279], 'are': [283], 'infrequent': [284], 'nAMD,': [286], 'often': [287], 'leading': [288], 'poor': [290], 'outcomes': [292, 342], 'related': [293, 350], 'fibrosis.': [296], 'We': [297], 'describe': [298], 'alternate': [300], 'occurring': [303], 'early': [307], 'treated': [311], 'therapy': [318], 'which': [320], 'tissue': [323], 'is': [324], 'enveloped': [325], 'producing': [330], 'pattern.': [334], 'These': [335], 'appear': [337], 'have': [339], 'better': [340], 'than': [343], 'typically': [344], 'seen': [345], 'outer': [353], 'damage.': [355]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2518857381', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-09-24T17:03:11.288029', 'created_date': '2016-09-23'}