Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2518797427', 'doi': 'https://doi.org/10.18632/oncotarget.12004', 'title': 'Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer', 'display_name': 'Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer', 'publication_year': 2016, 'publication_date': '2016-09-13', 'ids': {'openalex': 'https://openalex.org/W2518797427', 'doi': 'https://doi.org/10.18632/oncotarget.12004', 'mag': '2518797427', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27634881', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5342519'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.12004', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=12004&path%5B%5D=37988', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=12004&path%5B%5D=37988', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102082049', 'display_name': 'Anna Berg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}, {'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Anna Berg', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}, {'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079476137', 'display_name': 'Kristine E. Fasmer', 'orcid': 'https://orcid.org/0000-0001-8773-7870'}, 'institutions': [{'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Kristine E. Fasmer', 'raw_affiliation_strings': ['Department of Radiology, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050930264', 'display_name': 'Karen Klepsland Mauland', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}, {'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Karen K. Mauland', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}, {'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024780911', 'display_name': 'Sigmund Ytre‐Hauge', 'orcid': 'https://orcid.org/0000-0002-8004-0584'}, 'institutions': [{'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}, {'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Sigmund Ytre-Hauge', 'raw_affiliation_strings': ['Department of Radiology, Haukeland University Hospital, Norway', 'Section of Radiology, Department of Clinical Medicine, University of Bergen, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}, {'raw_affiliation_string': 'Section of Radiology, Department of Clinical Medicine, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046533177', 'display_name': 'Erling A. Høivik', 'orcid': 'https://orcid.org/0000-0003-0680-765X'}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}, {'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Erling A. Hoivik', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}, {'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035978224', 'display_name': 'J. Husby', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}, {'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Jenny A. Husby', 'raw_affiliation_strings': ['Department of Radiology, Haukeland University Hospital, Norway', 'Section of Radiology, Department of Clinical Medicine, University of Bergen, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}, {'raw_affiliation_string': 'Section of Radiology, Department of Clinical Medicine, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051745771', 'display_name': 'Ingvild L. Tangen', 'orcid': 'https://orcid.org/0000-0002-1760-0980'}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}, {'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Ingvild L. Tangen', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}, {'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032174631', 'display_name': 'Jone Trovik', 'orcid': 'https://orcid.org/0000-0002-3808-6407'}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}, {'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Jone Trovik', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}, {'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079629995', 'display_name': 'Mari K. Halle', 'orcid': 'https://orcid.org/0000-0002-2660-8271'}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}, {'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Mari K. Halle', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}, {'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034582669', 'display_name': 'Kathrine Woie', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Kathrine Woie', 'raw_affiliation_strings': ['Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019754075', 'display_name': 'Line Bjørge', 'orcid': 'https://orcid.org/0000-0002-0240-2770'}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}, {'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Line Bjørge', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}, {'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063053273', 'display_name': 'Atle Bjørnerud', 'orcid': 'https://orcid.org/0000-0002-3486-3141'}, 'institutions': [{'id': 'https://openalex.org/I184942183', 'display_name': 'University of Oslo', 'ror': 'https://ror.org/01xtthb56', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I184942183']}, {'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Atle Bjørnerud', 'raw_affiliation_strings': ['Department of Physics, University of Oslo, Norway', 'The Intervention Center, Oslo University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Physics, University of Oslo, Norway', 'institution_ids': ['https://openalex.org/I184942183']}, {'raw_affiliation_string': 'The Intervention Center, Oslo University Hospital, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049107000', 'display_name': 'Helga B. Salvesen', 'orcid': 'https://orcid.org/0000-0001-8592-2239'}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}, {'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Helga B. Salvesen', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}, {'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039037599', 'display_name': 'Henrica M.J. Werner', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}, {'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Henrica M. J. Werner', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}, {'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035785989', 'display_name': 'Camilla Krakstad', 'orcid': 'https://orcid.org/0000-0002-0174-8139'}, 'institutions': [{'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}, {'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Camilla Krakstad', 'raw_affiliation_strings': ['Center for Cancer Biomarkers, Department of Biomedicine, University of Bergen, Norway', 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Gynecology and Obstetrics, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}, {'raw_affiliation_string': 'Center for Cancer Biomarkers, Department of Biomedicine, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5045128636', 'display_name': 'Ingfrid S. Haldorsen', 'orcid': 'https://orcid.org/0000-0001-9313-7564'}, 'institutions': [{'id': 'https://openalex.org/I2800740805', 'display_name': 'Haukeland University Hospital', 'ror': 'https://ror.org/03np4e098', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800740805']}, {'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Ingfrid S. Haldorsen', 'raw_affiliation_strings': ['Department of Radiology, Haukeland University Hospital, Norway', 'Section of Radiology, Department of Clinical Medicine, University of Bergen, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Haukeland University Hospital, Norway', 'institution_ids': ['https://openalex.org/I2800740805']}, {'raw_affiliation_string': 'Section of Radiology, Department of Clinical Medicine, University of Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5102082049'], 'corresponding_institution_ids': ['https://openalex.org/I4432739', 'https://openalex.org/I2800740805'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.679, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 31, 'citation_normalized_percentile': {'value': 0.829729, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '7', 'issue': '43', 'first_page': '69844', 'last_page': '69856'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10631', 'display_name': 'Metabolic Reprogramming in Cancer Biology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10631', 'display_name': 'Metabolic Reprogramming in Cancer Biology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11054', 'display_name': 'Pheochromocytoma and Paraganglioma', 'score': 0.9939, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10422', 'display_name': 'Molecular Mechanisms of Angiogenesis and Vascular Function', 'score': 0.9938, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hypoxia', 'display_name': 'Hypoxia (environmental)', 'score': 0.68046236}, {'id': 'https://openalex.org/keywords/tumor-hypoxia', 'display_name': 'Tumor Hypoxia', 'score': 0.625798}, {'id': 'https://openalex.org/keywords/endothelial-cell-behavior', 'display_name': 'endothelial cell behavior', 'score': 0.537459}, {'id': 'https://openalex.org/keywords/tumor-vasculature', 'display_name': 'tumor vasculature', 'score': 0.510403}, {'id': 'https://openalex.org/keywords/gene-signature', 'display_name': 'Gene signature', 'score': 0.41237253}], 'concepts': [{'id': 'https://openalex.org/C16930146', 'wikidata': 'https://www.wikidata.org/wiki/Q4381253', 'display_name': 'Stromal cell', 'level': 2, 'score': 0.7995547}, {'id': 'https://openalex.org/C7836513', 'wikidata': 'https://www.wikidata.org/wiki/Q1641506', 'display_name': 'Hypoxia (environmental)', 'level': 3, 'score': 0.68046236}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.6013727}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.591219}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.49312684}, {'id': 'https://openalex.org/C2780394083', 'wikidata': 'https://www.wikidata.org/wiki/Q539568', 'display_name': 'Angiogenesis', 'level': 2, 'score': 0.47913048}, {'id': 'https://openalex.org/C2779081379', 'wikidata': 'https://www.wikidata.org/wiki/Q7852677', 'display_name': 'Tumor hypoxia', 'level': 3, 'score': 0.44843808}, {'id': 'https://openalex.org/C2779733811', 'wikidata': 'https://www.wikidata.org/wiki/Q5531562', 'display_name': 'Gene signature', 'level': 4, 'score': 0.41237253}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.35885188}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.31463885}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.26719263}, {'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.16952494}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.14150846}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.070751816}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C540031477', 'wikidata': 'https://www.wikidata.org/wiki/Q629', 'display_name': 'Oxygen', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D051795', 'descriptor_name': 'Hypoxia-Inducible Factor 1, alpha Subunit', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D000072645', 'descriptor_name': 'Cancer-Associated Fibroblasts', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015687', 'descriptor_name': 'Cell Hypoxia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016889', 'descriptor_name': 'Endometrial Neoplasms', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019788', 'descriptor_name': 'Fluorodeoxyglucose F18', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000072078', 'descriptor_name': 'Positron Emission Tomography Computed Tomography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.12004', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=12004&path%5B%5D=37988', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5342519', 'pdf_url': 'https://europepmc.org/articles/pmc5342519?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342519', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/1956/16366', 'pdf_url': 'https://bora.uib.no/bora-xmlui/bitstream/1956/16366/3/12004-180776-3-PB.pdf', 'source': {'id': 'https://openalex.org/S4306400085', 'display_name': 'Bergen Open Research Archive (BORA) (University of Bergen)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I4432739', 'host_organization_name': 'University of Bergen', 'host_organization_lineage': ['https://openalex.org/I4432739'], 'host_organization_lineage_names': ['University of Bergen'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10852/55706', 'pdf_url': 'https://www.duo.uio.no/bitstream/10852/55706/1/12004-180776-3-PB.pdf', 'source': {'id': 'https://openalex.org/S4306401716', 'display_name': 'Duo Research Archive (University of Oslo)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I184942183', 'host_organization_name': 'University of Oslo', 'host_organization_lineage': ['https://openalex.org/I184942183'], 'host_organization_lineage_names': ['University of Oslo'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27634881', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.12004', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=12004&path%5B%5D=37988', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.77, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 51, 'referenced_works': ['https://openalex.org/W1501009914', 'https://openalex.org/W1760866685', 'https://openalex.org/W1769510858', 'https://openalex.org/W1898937566', 'https://openalex.org/W1963719232', 'https://openalex.org/W1982709079', 'https://openalex.org/W1989312464', 'https://openalex.org/W1990412032', 'https://openalex.org/W1995237066', 'https://openalex.org/W1998664010', 'https://openalex.org/W2004271709', 'https://openalex.org/W2014648810', 'https://openalex.org/W2019315793', 'https://openalex.org/W2027578770', 'https://openalex.org/W2028046629', 'https://openalex.org/W2030575063', 'https://openalex.org/W2033278321', 'https://openalex.org/W2037707039', 'https://openalex.org/W2040481122', 'https://openalex.org/W2051544608', 'https://openalex.org/W2056574134', 'https://openalex.org/W2062809449', 'https://openalex.org/W2063096082', 'https://openalex.org/W2063932838', 'https://openalex.org/W2069518226', 'https://openalex.org/W2071359503', 'https://openalex.org/W2074399919', 'https://openalex.org/W2080274549', 'https://openalex.org/W2081995389', 'https://openalex.org/W2087844366', 'https://openalex.org/W2097180278', 'https://openalex.org/W2101037339', 'https://openalex.org/W2108695923', 'https://openalex.org/W2108984461', 'https://openalex.org/W2112003796', 'https://openalex.org/W2114903592', 'https://openalex.org/W2117692326', 'https://openalex.org/W2118655588', 'https://openalex.org/W2121604817', 'https://openalex.org/W2130410032', 'https://openalex.org/W2144273819', 'https://openalex.org/W2144961030', 'https://openalex.org/W2152027463', 'https://openalex.org/W2155113800', 'https://openalex.org/W2157589417', 'https://openalex.org/W2167761137', 'https://openalex.org/W2270969662', 'https://openalex.org/W2399708058', 'https://openalex.org/W2580449060', 'https://openalex.org/W327156816', 'https://openalex.org/W4210989197'], 'related_works': ['https://openalex.org/W45602473', 'https://openalex.org/W3191480413', 'https://openalex.org/W3039082282', 'https://openalex.org/W3031487600', 'https://openalex.org/W2747358211', 'https://openalex.org/W2531963904', 'https://openalex.org/W2408197587', 'https://openalex.org/W2132719707', 'https://openalex.org/W2052685250', 'https://openalex.org/W1571345353'], 'abstract_inverted_index': {'//': [0], 'Anna': [1, 171], 'Berg': [2], '1,': [3, 14, 25, 37, 42, 48, 57, 68, 75], '2': [4, 15, 26, 38, 43, 49, 53, 58, 69, 76, 103], ',': [5, 10, 16, 21, 27, 33, 39, 44, 50, 54, 59, 64, 70, 77, 83], 'Kristine': [6], 'E.': [7], 'Fasmer': [8], '3': [9, 113], 'Karen': [11], 'K.': [12, 46], 'Mauland': [13], 'Sigmund': [17], 'Ytre-Hauge': [18], '3,': [19, 31, 87], '4': [20, 32, 121], 'Erling': [22], 'A.': [23, 29], 'Hoivik': [24], 'Jenny': [28], 'Husby': [30], 'Ingvild': [34], 'L.': [35], 'Tangen': [36], 'Jone': [40], 'Trovik': [41], 'Mari': [45], 'Halle': [47], 'Kathrine': [51], 'Woie': [52], 'Line': [55], 'Bjørge': [56], 'Atle': [60], 'Bjørnerud': [61], '5,': [62], '6': [63, 141], 'Helga': [65], 'B.': [66], 'Salvesen': [67], 'Henrica': [71], 'M.': [72], 'J.': [73], 'Werner': [74], 'Camilla': [78], 'Krakstad': [79], '2,': [80], '7,': [81], '*': [82, 89, 161], 'Ingfrid': [84], 'S.': [85], 'Haldorsen': [86], '4,': [88], '1': [90], 'Center': [91, 150], 'for': [92, 151, 432], 'Cancer': [93, 152], 'Biomarkers,': [94, 153], 'Department': [95, 104, 114, 125, 134, 154], 'of': [96, 100, 105, 115, 123, 126, 130, 135, 138, 155, 158, 214, 237, 293, 311, 353], 'Clinical': [97, 127], 'Science,': [98], 'University': [99, 110, 118, 129, 137, 146, 157], 'Bergen,': [101, 131, 159], 'Norway': [102, 112, 120, 132, 140, 148, 160], 'Gynecology': [106], 'and': [107, 202, 207, 224, 245, 256, 319, 369, 406, 422, 427], 'Obstetrics,': [108], 'Haukeland': [109, 117], 'Hospital,': [111, 119, 147], 'Radiology,': [116, 124], 'Section': [122], 'Medicine,': [128], '5': [133], 'Physics,': [136], 'Oslo,': [139], 'The': [142], 'Intervention': [143], 'Center,': [144], 'Oslo': [145], '7': [149], 'Biomedicine,': [156], 'These': [162], 'authors': [163], 'contributed': [164], 'equally': [165], 'to': [166, 204, 300, 358], 'this': [167, 389], 'work': [168], 'Correspondence': [169], 'to:': [170], 'Berg,': [172], 'email:': [173], '[email protected]': [174], 'Keywords:': [175], 'endometrial': [176, 178, 221], 'carcinoma,': [177], 'hyperplasia,': [179], 'HIF-1α,': [180, 316], 'MRI,': [181], 'FDG-PET/CT': [182], 'Received:': [183], 'July': [184], '02,': [185], '2016 ': [186, 190], 'Accepted:': [187], 'September': [188, 192], '04,': [189], 'Published:': [191], '13,': [193], '2016': [194], 'ABSTRACT': [195], 'Hypoxia': [196], 'is': [197, 407], 'frequent': [198], 'in': [199, 220, 242, 269, 278, 289, 384, 404], 'solid': [200], 'tumors': [201, 326], 'linked': [203, 357], 'aggressive': [205], 'phenotypes': [206], 'therapy': [208], 'resistance.': [209], 'We': [210, 250, 335], 'explored': [211, 240], 'expression': [212, 260, 286, 306, 341, 352, 400], 'patterns': [213], 'the': [215, 243, 246, 290], 'proposed': [216], 'hypoxia': [217, 359], 'marker': [218], 'HIF-1α': [219, 238, 255, 259, 273, 284, 305, 340, 399], 'cancer': [222], '(EC)': [223], 'investigate': [225], 'whether': [226], 'preoperative': [227, 328], 'functional': [228, 329], 'imaging': [229, 330, 423], 'parameters': [230], 'are': [231], 'associated': [232, 263, 342, 408], 'with': [233, 264, 309, 327, 343, 362, 386, 409], 'tumor': [234, 248, 364, 411], 'hypoxia.': [235], 'Expression': [236], 'was': [239, 287, 307], 'both': [241], 'epithelial': [244, 254], 'stromal': [247, 258, 272, 283, 304, 339, 398], 'component.': [249], 'found': [251, 336], 'that': [252, 337, 396], 'low': [253, 363], 'high': [257, 338, 344, 397], 'were': [261, 378], 'significantly': [262, 299], 'reduced': [265, 402], 'disease': [266], 'specific': [267], 'survival': [268, 403], 'EC.': [270], 'Only': [271], 'had': [274], 'independent': [275], 'prognostic': [276], 'value': [277], 'Cox': [279], 'regression': [280], 'analysis.': [281], 'High': [282, 303, 351], 'protein': [285], 'rare': [288], 'premalignant': [291], 'lesions': [292, 387], 'complex': [294], 'atypical': [295], 'hyperplasia': [296], 'but': [297], 'increased': [298, 370, 410], 'invasive': [301], 'cancer.': [302], 'correlated': [308, 361], 'overexpression': [310], 'important': [312], 'genes': [313], 'downstream': [314], 'from': [315], 'i.e.': [317], 'VEGFA': [318], 'SLC2A1': [320], '(': [321], 'GLUT1': [322], ').': [323], 'Detecting': [324], 'hypoxic': [325], 'might': [331], 'have': [332], 'therapeutic': [333, 382], 'benefits.': [334], 'total': [345], 'lesion': [346], 'glycolysis': [347], '(TLG)': [348], 'at': [349, 367, 413], 'PET/CT.': [350], 'a': [354, 418], 'gene': [355, 390], 'signature': [356], 'also': [360, 428], 'blood': [365], 'flow': [366], 'DCE-MRI': [368], 'metabolism': [371, 412], 'measured': [372], 'by': [373], 'FDG-PET.': [374], 'PI3K': [375], 'pathway': [376], 'inhibitors': [377], 'identified': [379], 'as': [380], 'potential': [381], 'compounds': [383], 'patients': [385], 'overexpressing': [388], 'signature.': [391], 'In': [392], 'conclusion,': [393], 'we': [394, 416], 'show': [395], 'predicts': [401], 'EC': [405], 'FDG-PET/CT.': [414], 'Importantly;': [415], 'demonstrate': [417], 'correlation': [419], 'between': [420], 'tissue': [421], 'biomarkers': [424], 'reflecting': [425], 'hypoxia,': [426], 'possible': [429], 'treatment': [430], 'targets': [431], 'selected': [433], 'patients.': [434]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2518797427', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 4}], 'updated_date': '2024-09-06T22:31:30.490237', 'created_date': '2016-09-23'}