Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2517103182', 'doi': 'https://doi.org/10.18632/oncotarget.11615', 'title': 'Methionine deprivation suppresses triple-negative breast cancer metastasis<i>in vitro</i>and<i>in vivo</i>', 'display_name': 'Methionine deprivation suppresses triple-negative breast cancer metastasis<i>in vitro</i>and<i>in vivo</i>', 'publication_year': 2016, 'publication_date': '2016-08-25', 'ids': {'openalex': 'https://openalex.org/W2517103182', 'doi': 'https://doi.org/10.18632/oncotarget.11615', 'mag': '2517103182', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27579534', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5341870'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.11615', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=11615&path%5B%5D=36779', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=11615&path%5B%5D=36779', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5026399394', 'display_name': 'Hyein Jeon', 'orcid': 'https://orcid.org/0000-0002-5221-2844'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}, {'id': 'https://openalex.org/I4210120602', 'display_name': 'Advanced Institute of Convergence Technology', 'ror': 'https://ror.org/01w62yz22', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hyein Jeon', 'raw_affiliation_strings': ['Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}, {'raw_affiliation_string': 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100447929', 'display_name': 'Jae Hwan Kim', 'orcid': 'https://orcid.org/0000-0001-9775-165X'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}, {'id': 'https://openalex.org/I4210120602', 'display_name': 'Advanced Institute of Convergence Technology', 'ror': 'https://ror.org/01w62yz22', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jae Hwan Kim', 'raw_affiliation_strings': ['Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}, {'raw_affiliation_string': 'Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'institution_ids': ['https://openalex.org/I4210120602', 'https://openalex.org/I139264467']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100398838', 'display_name': 'Eunjung Lee', 'orcid': 'https://orcid.org/0000-0002-8287-6131'}, 'institutions': [{'id': 'https://openalex.org/I4210114577', 'display_name': 'Korea Food Research Institute', 'ror': 'https://ror.org/028jp5z02', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210114577']}, {'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}, {'id': 'https://openalex.org/I4210120602', 'display_name': 'Advanced Institute of Convergence Technology', 'ror': 'https://ror.org/01w62yz22', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Eunjung Lee', 'raw_affiliation_strings': ['Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'Traditional Alcoholic Beverage Research Team, Korea Food Research Institute, Seongnam, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Traditional Alcoholic Beverage Research Team, Korea Food Research Institute, Seongnam, Republic of Korea', 'institution_ids': ['https://openalex.org/I4210114577']}, {'raw_affiliation_string': 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}, {'raw_affiliation_string': 'Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'institution_ids': ['https://openalex.org/I4210120602', 'https://openalex.org/I139264467']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072607811', 'display_name': 'Young Jin Jang', 'orcid': 'https://orcid.org/0000-0003-0553-2498'}, 'institutions': [{'id': 'https://openalex.org/I4210114577', 'display_name': 'Korea Food Research Institute', 'ror': 'https://ror.org/028jp5z02', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210114577']}, {'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}, {'id': 'https://openalex.org/I4210120602', 'display_name': 'Advanced Institute of Convergence Technology', 'ror': 'https://ror.org/01w62yz22', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Young Jin Jang', 'raw_affiliation_strings': ['Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'Metabolic Mechanism Research Group, Korea Food Research Institute, Seongnam, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Metabolic Mechanism Research Group, Korea Food Research Institute, Seongnam, Republic of Korea', 'institution_ids': ['https://openalex.org/I4210114577']}, {'raw_affiliation_string': 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}, {'raw_affiliation_string': 'Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'institution_ids': ['https://openalex.org/I4210120602', 'https://openalex.org/I139264467']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045877476', 'display_name': 'Joe Eun Son', 'orcid': 'https://orcid.org/0000-0003-3066-2796'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}, {'id': 'https://openalex.org/I4210120602', 'display_name': 'Advanced Institute of Convergence Technology', 'ror': 'https://ror.org/01w62yz22', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Joe Eun Son', 'raw_affiliation_strings': ['Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}, {'raw_affiliation_string': 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084676976', 'display_name': 'Jung Yeon Kwon', 'orcid': 'https://orcid.org/0000-0002-5665-5028'}, 'institutions': [{'id': 'https://openalex.org/I166722992', 'display_name': 'University of Massachusetts Chan Medical School', 'ror': 'https://ror.org/0464eyp60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I166722992']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jung Yeon Kwon', 'raw_affiliation_strings': ['Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA'], 'affiliations': [{'raw_affiliation_string': 'Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA', 'institution_ids': ['https://openalex.org/I166722992']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001150627', 'display_name': 'Tae‐Gyu Lim', 'orcid': 'https://orcid.org/0000-0001-6930-9565'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}, {'id': 'https://openalex.org/I4210114577', 'display_name': 'Korea Food Research Institute', 'ror': 'https://ror.org/028jp5z02', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210114577']}, {'id': 'https://openalex.org/I4210120602', 'display_name': 'Advanced Institute of Convergence Technology', 'ror': 'https://ror.org/01w62yz22', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Tae-gyu Lim', 'raw_affiliation_strings': ['Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'Division of Strategic Food Research, Korea Food Research Institute, Seongnam, Republic of Korea', 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}, {'raw_affiliation_string': 'Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}, {'raw_affiliation_string': 'Division of Strategic Food Research, Korea Food Research Institute, Seongnam, Republic of Korea', 'institution_ids': ['https://openalex.org/I4210114577']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100429324', 'display_name': 'Sung‐Hoon Kim', 'orcid': 'https://orcid.org/0000-0002-1570-3230'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sunghoon Kim', 'raw_affiliation_strings': ['Medicinal Bioconvergence Research Center, College of Pharmacy, Seoul National University, Seoul, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Medicinal Bioconvergence Research Center, College of Pharmacy, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028077878', 'display_name': 'Jung Han Yoon Park', 'orcid': 'https://orcid.org/0000-0002-5518-4279'}, 'institutions': [{'id': 'https://openalex.org/I146824383', 'display_name': 'Hallym University', 'ror': 'https://ror.org/03sbhge02', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I146824383']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jung Han Yoon Park', 'raw_affiliation_strings': ['Department of Food Science and Nutrition, Hallym University, Chuncheon, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Food Science and Nutrition, Hallym University, Chuncheon, Republic of Korea', 'institution_ids': ['https://openalex.org/I146824383']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101418380', 'display_name': 'Jong‐Eun Kim', 'orcid': 'https://orcid.org/0000-0002-5030-6126'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}, {'id': 'https://openalex.org/I4210120602', 'display_name': 'Advanced Institute of Convergence Technology', 'ror': 'https://ror.org/01w62yz22', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jong-Eun Kim', 'raw_affiliation_strings': ['Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}, {'raw_affiliation_string': 'Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5006050449', 'display_name': 'Ki Won Lee', 'orcid': 'https://orcid.org/0000-0001-6302-2432'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}, {'id': 'https://openalex.org/I4210120602', 'display_name': 'Advanced Institute of Convergence Technology', 'ror': 'https://ror.org/01w62yz22', 'country_code': 'KR', 'type': 'facility', 'lineage': ['https://openalex.org/I139264467', 'https://openalex.org/I4210120602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Ki Won Lee', 'raw_affiliation_strings': ['Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Major in Biomodulation, Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea', 'institution_ids': ['https://openalex.org/I139264467']}, {'raw_affiliation_string': 'Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea', 'institution_ids': ['https://openalex.org/I4210120602', 'https://openalex.org/I139264467']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.302, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 84, 'citation_normalized_percentile': {'value': 0.904393, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '7', 'issue': '41', 'first_page': '67223', 'last_page': '67234'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12996', 'display_name': 'Engineering Bacteria for Cancer Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12996', 'display_name': 'Engineering Bacteria for Cancer Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10631', 'display_name': 'Metabolic Reprogramming in Cancer Biology', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cancer-therapy', 'display_name': 'Cancer Therapy', 'score': 0.524064}, {'id': 'https://openalex.org/keywords/cancer-metabolism', 'display_name': 'Cancer Metabolism', 'score': 0.512734}, {'id': 'https://openalex.org/keywords/tumor-suppression', 'display_name': 'Tumor Suppression', 'score': 0.512044}, {'id': 'https://openalex.org/keywords/cancer-cell-metabolism', 'display_name': 'Cancer Cell Metabolism', 'score': 0.504018}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.55989665}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.52953565}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.47446948}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.4098716}, {'id': 'https://openalex.org/C74909509', 'wikidata': 'https://www.wikidata.org/wiki/Q10387', 'display_name': 'Gerontology', 'level': 1, 'score': 0.38188863}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3684297}], 'mesh': [{'descriptor_ui': 'D008715', 'descriptor_name': 'Methionine', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': True}, {'descriptor_ui': 'D064726', 'descriptor_name': 'Triple Negative Breast Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D064726', 'descriptor_name': 'Triple Negative Breast Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008715', 'descriptor_name': 'Methionine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008807', 'descriptor_name': 'Mice, Inbred BALB C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009361', 'descriptor_name': 'Neoplasm Invasiveness', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D009361', 'descriptor_name': 'Neoplasm Invasiveness', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064726', 'descriptor_name': 'Triple Negative Breast Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.11615', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=11615&path%5B%5D=36779', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5341870', 'pdf_url': 'https://europepmc.org/articles/pmc5341870?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341870', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27579534', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.11615', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=11615&path%5B%5D=36779', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/2', 'score': 0.76, 'display_name': 'Zero hunger'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1555009525', 'https://openalex.org/W1802829593', 'https://openalex.org/W1892721446', 'https://openalex.org/W1954837718', 'https://openalex.org/W1956645860', 'https://openalex.org/W1965110439', 'https://openalex.org/W1965815494', 'https://openalex.org/W1980181091', 'https://openalex.org/W1983243616', 'https://openalex.org/W1985256688', 'https://openalex.org/W1987228194', 'https://openalex.org/W1988976467', 'https://openalex.org/W1993537854', 'https://openalex.org/W2008274006', 'https://openalex.org/W2015898183', 'https://openalex.org/W2021038840', 'https://openalex.org/W2030067084', 'https://openalex.org/W2036398199', 'https://openalex.org/W2041014807', 'https://openalex.org/W2041601692', 'https://openalex.org/W2041805523', 'https://openalex.org/W2063606515', 'https://openalex.org/W2080051364', 'https://openalex.org/W2085811382', 'https://openalex.org/W2097259163', 'https://openalex.org/W2106787323', 'https://openalex.org/W2130422617', 'https://openalex.org/W2133147483', 'https://openalex.org/W2137458142', 'https://openalex.org/W2137495186', 'https://openalex.org/W2139517025', 'https://openalex.org/W2154585426', 'https://openalex.org/W2161892290', 'https://openalex.org/W2163926478', 'https://openalex.org/W2170602872', 'https://openalex.org/W2209093312', 'https://openalex.org/W2308070604', 'https://openalex.org/W2418622096', 'https://openalex.org/W2917837889'], 'related_works': ['https://openalex.org/W2892677547', 'https://openalex.org/W2557359331', 'https://openalex.org/W2391409986', 'https://openalex.org/W2159000141', 'https://openalex.org/W2073527559', 'https://openalex.org/W2037631372', 'https://openalex.org/W2030889776', 'https://openalex.org/W1979139803', 'https://openalex.org/W1974041167', 'https://openalex.org/W1966504330'], 'abstract_inverted_index': {'//': [0], 'Hyein': [1], 'Jeon': [2], '1,': [3, 10, 16, 24, 30, 40, 56, 62], '2,': [4, 11, 17, 41], '*': [5, 12, 19, 182], ',': [6, 13, 20, 26, 32, 37, 43, 47, 53, 58], 'Jae': [7], 'Hwan': [8], 'Kim': [9, 45, 55], 'Eunjung': [14], 'Lee': [15, 61], '3,': [18], 'Young': [21], 'Jin': [22], 'Jang': [23], '2,4': [25], 'Joe': [27], 'Eun': [28], 'Son': [29], '2': [31, 57, 63, 87], 'Jung': [33, 48], 'Yeon': [34], 'Kwon': [35], '5': [36, 127], 'Tae-gyu': [38], 'Lim': [39], '6': [42, 140], 'Sunghoon': [44], '7': [46, 154], 'Han': [49], 'Yoon': [50], 'Park': [51], '8': [52, 169], 'Jong-Eun': [54, 193], 'Ki': [59, 197], 'Won': [60, 198], '1': [64, 340, 359], 'Major': [65], 'in': [66, 129, 341], 'Biomodulation,': [67], 'Department': [68, 170], 'of': [69, 85, 90, 98, 112, 125, 133, 142, 152, 160, 167, 171, 180, 248, 256, 298, 307, 319, 328, 335, 338], 'Agricultural': [70], 'Biotechnology': [71], 'and': [72, 77, 174, 266, 296, 316, 323, 354], 'Research': [73, 104, 108, 117, 121, 148, 157], 'Institute': [74], 'for': [75, 233, 393], 'Agriculture': [76], 'Life': [78], 'Sciences,': [79], 'Seoul': [80, 93, 162], 'National': [81, 94, 163], 'University,': [82, 95, 164, 177], 'Seoul,': [83, 165], 'Republic': [84, 97, 111, 124, 151, 166, 179], 'Korea': [86, 99, 106, 113, 119, 126, 146, 153, 168, 181], 'Advanced': [88], 'Institutes': [89], 'Convergence': [91], 'Technology,': [92], 'Suwon,': [96], '3': [100], 'Traditional': [101], 'Alcoholic': [102], 'Beverage': [103], 'Team,': [105], 'Food': [107, 120, 144, 147, 172], 'Institute,': [109, 122, 149], 'Seongnam,': [110, 123, 150], '4': [114], 'Metabolic': [115], 'Mechanism': [116], 'Group,': [118], 'Program': [128], 'Molecular': [130], 'Medicine,': [131], 'University': [132], 'Massachusetts': [134], 'Medical': [135], 'School,': [136], 'Worcester,': [137], 'MA,': [138], 'USA': [139], 'Division': [141], 'Strategic': [143], 'Research,': [145], 'Medicinal': [155], 'Bioconvergence': [156], 'Center,': [158], 'College': [159], 'Pharmacy,': [161], 'Science': [173], 'Nutrition,': [175], 'Hallym': [176], 'Chuncheon,': [178], 'These': [183], 'authors': [184], 'have': [185, 226], 'contributed': [186], 'equally': [187], 'to': [188, 237, 373], 'this': [189], 'work': [190], 'Correspondence': [191], 'to:': [192], 'Kim,': [194], 'email:': [195, 200], '[email protected]': [196], 'Lee,': [199], '[email protected]': [201], 'Keywords:': [202], 'methionine,': [203], 'triple-negative': [204, 259], 'breast': [205, 260], 'cancer,': [206], 'metastasis,': [207, 329], 'cancer': [208, 234, 261, 300, 396], 'therapy': [209, 232], 'Received:': [210], 'March': [211], '25,': [212, 220], '2016': [213, 217, 221], 'Accepted:': [214], 'July': [215], '27,': [216], 'Published:': [218], 'August': [219], 'ABSTRACT': [222], 'Nutrient': [223], 'deprivation': [224, 251, 287, 303], 'strategies': [225], 'been': [227], 'proposed': [228], 'as': [229, 269, 271, 311, 313], 'an': [230], 'adjuvant': [231], 'cells': [235], 'due': [236], 'their': [238], 'increased': [239], 'metabolic': [240], 'demand.': [241], 'We': [242], 'examined': [243], 'the': [244, 253, 257, 272, 280, 289, 294, 305, 314, 332, 348, 364, 376], 'specific': [245], 'inhibitory': [246, 291], 'effects': [247, 292], 'amino': [249, 283], 'acid': [250], 'on': [252, 293, 363, 375], 'metastatic': [254], 'phenotypes': [255], 'human': [258], '(TNBC)': [262], 'cell': [263], 'lines': [264], 'MDA-MB-231': [265, 342], 'Hs': [267], '578T,': [268], 'well': [270, 312], 'orthotopic': [273], '4T1': [274], 'mouse': [275], 'TNBC': [276], 'tumor': [277], 'model.': [278], 'Among': [279], '10': [281], 'essential': [282], 'acids': [284], 'tested,': [285], 'methionine': [286, 345, 385], 'elicited': [288], 'strongest': [290], 'migration': [295], 'invasion': [297], 'these': [299, 381], 'cells.': [301, 343], 'Methionine': [302], 'reduced': [304], 'phosphorylation': [306], 'focal': [308], 'adhesion': [309], 'kinase,': [310], 'activity': [315], 'mRNA': [317, 333, 360], 'expression': [318, 334], 'matrix': [320], 'metalloproteinases': [321], 'MMP-2': [322], 'MMP-9,': [324], 'two': [325], 'major': [326], 'markers': [327], 'while': [330], 'increasing': [331], 'tissue': [336], 'inhibitor': [337, 358], 'metalloproteinase': [339], 'Furthermore,': [344], 'restriction': [346, 386], 'downregulated': [347], 'metastasis-related': [349], 'factor': [350], 'urokinase': [351], 'plasminogen': [352, 356], 'activatior': [353], 'upregulated': [355], 'activator': [357], 'expression.': [361], 'Animals': [362], 'methionine-deprived': [365], 'diet': [366], 'showed': [367], 'lower': [368], 'lung': [369], 'metastasis': [370], 'rates': [371], 'compared': [372], 'mice': [374], 'control': [377], 'diet.': [378], 'Taken': [379], 'together,': [380], 'results': [382], 'suggest': [383], 'that': [384], 'could': [387], 'provide': [388], 'a': [389], 'potential': [390], 'nutritional': [391], 'strategy': [392], 'more': [394], 'effective': [395], 'therapy.': [397]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2517103182', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 13}, {'year': 2021, 'cited_by_count': 15}, {'year': 2020, 'cited_by_count': 23}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 3}], 'updated_date': '2024-08-21T18:54:58.413820', 'created_date': '2016-09-16'}