Abstract: S-Adenosylmethionine-Dependent Methyltransferases, pp. 283-340 (1999) No AccessBACTERIAL DNA METHYLTRANSFERASESDAVID T. F. DRYDENDAVID T. F. DRYDENInstitute of Cell & Molecular Biology, University of Edinburgh The King's Buildings, Edinburgh EH9 3JR, United Kingdomhttps://doi.org/10.1142/9789812813077_0011Cited by:23 PreviousNext AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsRecommend to Library ShareShare onFacebookTwitterLinked InRedditEmail Abstract: The following sections are included: Introduction The DNA MTases Base flipping Scope of this chapter Biology of DNA MTases Dam and Dcm MTases R/M systems Antirestriction MTases Structural domains Target recognition domains (TRDs) AdoMet binding and catalytic domain Other domain structures Endonuclease DNA cleavage domains DNA helicase domains Classification of DNA MTases Type II R/M systems Type IIs R/M systems Multifunctional MTases Type I R/M systems Specificity (S) subunits Medication (M) subunits Restriction (R) subunits Type 1 1/2 R/M systems Bcgl-like R/M systems Type III R/M systems Type IV R/M systems Assembly of DNA MTases Chemical reactions of DNA MTases 5mC methylation N4mC and N6mA methylation Kinetics of DNA methylation Physical Mechanism Locating the DNA target sequence DNA binding affinity DNA footprinting Type II MTases DNA bending by type II MTases Footprinting of type I R/M enzymes Substrate-induced conformational changes in DNA MTases Crystallographic evidence Limited proteolysis of MTases Spectroscopic methods Hydrodynamic measurements Conformational changes in the DNA and nucleotide base flipping Mechanism of EcoRI N6mA MTase Summary Acknowledgements References FiguresReferencesRelatedDetailsCited By 23Williams–Beuren syndrome‐related methyltransferase WBSCR27: cofactor binding and cleavageSofia S. Mariasina, Chi‐Fon Chang, Olga A. Petrova, Sergey V. Efimov and Vladimir V. Klochkov et al.20 April 2020 | The FEBS Journal, Vol. 287, No. 24A model for the evolution of prokaryotic DNA restriction-modification systems based upon the structural malleability of Type I restriction-modification enzymesEdward K M Bower, Laurie P Cooper, Gareth A Roberts, John H White and Yvette Luyten et al.28 August 2018 | Nucleic Acids Research, Vol. 46, No. 17Diverse Functions of Restriction-Modification Systems in Addition to Cellular DefenseKommireddy Vasu and Valakunja Nagaraja1 Mar 2013 | Microbiology and Molecular Biology Reviews, Vol. 77, No. 1Organization of the BcgI restriction–modification protein for the transfer of one methyl group to DNARachel M. Smith, Alistair J. Jacklin, Jacqueline J. T. Marshall, Frank Sobott and Stephen E. Halford11 November 2012 | Nucleic Acids Research, Vol. 41, No. 1Exploring the DNA mimicry of the Ocr protein of phage T7Gareth A. Roberts, Augoustinos S. Stephanou, Nisha Kanwar, Angela Dawson and Laurie P. Cooper et al.7 June 2012 | Nucleic Acids Research, Vol. 40, No. 16DNA methyltransferases: Mechanistic models derived from kinetic analysisErnst G. Malygin and Stanley Hattman20 January 2012 | Critical Reviews in Biochemistry and Molecular Biology, Vol. 47, No. 2Structure and operation of the DNA-translocating type I DNA restriction enzymesChristopher K. Kennaway, James E. Taylor, Chun Feng Song, Wojciech Potrzebowski and William Nicholson et al.3 January 2012 | Genes & Development, Vol. 26, No. 1An investigation of the structural requirements for ATP hydrolysis and DNA cleavage by the EcoKI Type I DNA restriction and modification enzymeGareth A. Roberts, Laurie P. Cooper, John H. White, Tsueu-Ju Su and Jakob T. Zipprich et al.17 June 2011 | Nucleic Acids Research, Vol. 39, No. 17S -Adenosylmethionine Decreases Lipopolysaccharide-Induced Phosphodiesterase 4B2 and Attenuates Tumor Necrosis Factor Expression via cAMP/Protein Kinase A PathwayLeila Gobejishvili, Diana V. Avila, David F. Barker, Smita Ghare and David Henderson et al.25 January 2011 | Journal of Pharmacology and Experimental Therapeutics, Vol. 337, No. 2Sequence-specific covalent labelling of DNAAnna Gottfried and Elmar Weinhold22 March 2011 | Biochemical Society Transactions, Vol. 39, No. 2Diversity of DNA methyltransferases that recognize asymmetric target sequencesUrulangodi Kunhiraman Madhusoodanan and Desirazu N Rao26 February 2010 | Critical Reviews in Biochemistry and Molecular Biology, Vol. 45, No. 2Substrate specificity and biochemical properties of M3.BstF5I DNA methyltransferase from the BstF5I restriction-modification systemV. A. Chernukhin, V. V. Kuznetsov, D. A. Gonchar, Yu. G. Kashirina and N. A. Netesova et al.5 February 2010 | Biochemistry (Moscow), Vol. 75, No. 1The structure of M.EcoKI Type I DNA methyltransferase with a DNA mimic antirestriction proteinChristopher K. Kennaway, Agnieszka Obarska-Kosinska, John H. White, Irina Tuszynska and Laurie P. Cooper et al.11 December 2008 | Nucleic Acids Research, Vol. 37, No. 3Structure, function and mechanism of exocyclic DNA methyltransferasesShivakumara Bheemanaik, Yeturu V. R. Reddy and Desirazu N. Rao27 September 2006 | Biochemical Journal, Vol. 399, No. 2Isolation and Characterization of Biochemical Properties of DNA Methyltransferase FauIA Modifying the Second Cytosine in the Nonpalindromic Sequence 5′-CCCGC-3′V. A. Chernukhin, Yu. G. Kashirina, K. S. Sukhanova, M. A. Abdurashitov and D. A. Gonchar et al.1 Jun 2005 | Biochemistry (Moscow), Vol. 70, No. 6Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interfaceMonika Radlinska, Aneta Kondrzycka-Dada, Andrzej Piekarowicz and Janusz M. Bujnicki19 November 2004 | Proteins: Structure, Function, and Bioinformatics, Vol. 58, No. 2DNA methyltransferases from Neisseria meningitidis and Neisseria gonorrhoeae FA1090 associated with mismatch nicking endonucleasesAgnieszka Kwiatek, Monika Kobes, Kamil Olejnik and Andrzej Piekarowicz1 Jun 2004 | Microbiology, Vol. 150, No. 6Solubility engineering of the HhaI methyltransferaseDalia Daujotytė, Giedrius Vilkaitis, Laura Manelytė, Jack Skalicky and Thomas Szyperski et al.1 April 2003 | Protein Engineering, Design and Selection, Vol. 16, No. 4Beyond Watson and Crick: DNA Methylation and Molecular Enzymology of DNA MethyltransferasesAlbert Jeltsch2 Apr 2002 | ChemBioChem, Vol. 3, No. 4DNA MethylationDavid P Hornby22 March 2002Immigration control of DNA in bacteria: self versus non-selfNoreen E Murray1 Jan 2002 | Microbiology, Vol. 148, No. 1The proteolytic control of restriction activity in Escherichia coli K-12Victoria A. Doronina and Noreen E. Murray1 Jan 2001 | Molecular Microbiology, Vol. 39, No. 2Type I Restriction Systems: Sophisticated Molecular Machines (a Legacy of Bertani and Weigle)Noreen E. Murray1 Jun 2000 | Microbiology and Molecular Biology Reviews, Vol. 64, No. 2 S-Adenosylmethionine-Dependent MethyltransferasesMetrics History PDF download
Publication Year: 1999
Publication Date: 1999-07-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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Cited By Count: 58
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