Publication Information

{'id': 'https://openalex.org/W2497443468', 'doi': 'https://doi.org/10.1007/7653_2014_37', 'title': 'Quantitative Histopathology for Evaluation of In Vivo Biocompatibility Associated with Biomedical Implants', 'display_name': 'Quantitative Histopathology for Evaluation of In Vivo Biocompatibility Associated with Biomedical Implants', 'publication_year': 2014, 'publication_date': '2014-01-01', 'ids': {'openalex': 'https://openalex.org/W2497443468', 'doi': 'https://doi.org/10.1007/7653_2014_37', 'mag': '2497443468'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/7653_2014_37', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/7653_2014_37.pdf', 'source': {'id': 'https://openalex.org/S4210223905', 'display_name': 'Methods in pharmacology and toxicology', 'issn_l': '1557-2153', 'issn': ['1557-2153', '1940-6053'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315801', 'host_organization_name': 'Humana Press', 'host_organization_lineage': ['https://openalex.org/P4310315801'], 'host_organization_lineage_names': ['Humana Press'], 'type': 'book series'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'book-chapter', 'type_crossref': 'book-chapter', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://link.springer.com/content/pdf/10.1007/7653_2014_37.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5008559922', 'display_name': 'Robert B. Diller', 'orcid': 'https://orcid.org/0000-0002-7030-1277'}, 'institutions': [{'id': 'https://openalex.org/I2802351013', 'display_name': 'Flagstaff Medical Center', 'ror': 'https://ror.org/03sc3x439', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802351013']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert B. Diller', 'raw_affiliation_strings': ['Development Engineering Sciences, LLC, 2225 N. Gemini Dr., Suite W8, Box #2, Flagstaff, AZ, 86001, USA'], 'affiliations': [{'raw_affiliation_string': 'Development Engineering Sciences, LLC, 2225 N. Gemini Dr., Suite W8, Box #2, Flagstaff, AZ, 86001, USA', 'institution_ids': ['https://openalex.org/I2802351013']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025294547', 'display_name': 'Robert G. Audet', 'orcid': 'https://orcid.org/0009-0008-9230-5624'}, 'institutions': [{'id': 'https://openalex.org/I2802351013', 'display_name': 'Flagstaff Medical Center', 'ror': 'https://ror.org/03sc3x439', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802351013']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert G. Audet', 'raw_affiliation_strings': ['Development Engineering Sciences, LLC, 2225 N. Gemini Dr., Suite W8, Box #2, Flagstaff, AZ, 86001, USA'], 'affiliations': [{'raw_affiliation_string': 'Development Engineering Sciences, LLC, 2225 N. Gemini Dr., Suite W8, Box #2, Flagstaff, AZ, 86001, USA', 'institution_ids': ['https://openalex.org/I2802351013']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5050543620', 'display_name': 'Robert S. Kellar', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802351013', 'display_name': 'Flagstaff Medical Center', 'ror': 'https://ror.org/03sc3x439', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802351013']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert S. Kellar', 'raw_affiliation_strings': ['Development Engineering Sciences, LLC, 2225 N. Gemini Dr., Suite W8, Box #2, Flagstaff, AZ, 86001, USA'], 'affiliations': [{'raw_affiliation_string': 'Development Engineering Sciences, LLC, 2225 N. Gemini Dr., Suite W8, Box #2, Flagstaff, AZ, 86001, USA', 'institution_ids': ['https://openalex.org/I2802351013']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.967763, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 79, 'max': 81}, 'biblio': {'volume': None, 'issue': None, 'first_page': '153', 'last_page': '162'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10512', 'display_name': 'Orthopaedic implants and arthroplasty', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10512', 'display_name': 'Orthopaedic implants and arthroplasty', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11293', 'display_name': 'Orthopedic Infections and Treatments', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10105', 'display_name': 'Osteoarthritis Treatment and Mechanisms', 'score': 0.9901, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/biocompatibility', 'display_name': 'Biocompatibility', 'score': 0.952829}, {'id': 'https://openalex.org/keywords/biomaterial', 'display_name': 'Biomaterial', 'score': 0.79371166}], 'concepts': [{'id': 'https://openalex.org/C2777230088', 'wikidata': 'https://www.wikidata.org/wiki/Q864426', 'display_name': 'Biocompatibility', 'level': 2, 'score': 0.952829}, {'id': 'https://openalex.org/C2778414984', 'wikidata': 'https://www.wikidata.org/wiki/Q865663', 'display_name': 'Biomaterial', 'level': 2, 'score': 0.79371166}, {'id': 'https://openalex.org/C136229726', 'wikidata': 'https://www.wikidata.org/wiki/Q327092', 'display_name': 'Biomedical engineering', 'level': 1, 'score': 0.73576736}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.3962687}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3373199}, {'id': 'https://openalex.org/C191897082', 'wikidata': 'https://www.wikidata.org/wiki/Q11467', 'display_name': 'Metallurgy', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/7653_2014_37', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/7653_2014_37.pdf', 'source': {'id': 'https://openalex.org/S4210223905', 'display_name': 'Methods in pharmacology and toxicology', 'issn_l': '1557-2153', 'issn': ['1557-2153', '1940-6053'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315801', 'host_organization_name': 'Humana Press', 'host_organization_lineage': ['https://openalex.org/P4310315801'], 'host_organization_lineage_names': ['Humana Press'], 'type': 'book series'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/7653_2014_37', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/7653_2014_37.pdf', 'source': {'id': 'https://openalex.org/S4210223905', 'display_name': 'Methods in pharmacology and toxicology', 'issn_l': '1557-2153', 'issn': ['1557-2153', '1940-6053'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315801', 'host_organization_name': 'Humana Press', 'host_organization_lineage': ['https://openalex.org/P4310315801'], 'host_organization_lineage_names': ['Humana Press'], 'type': 'book series'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/9', 'display_name': 'Industry, innovation and infrastructure', 'score': 0.47}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 16, 'referenced_works': ['https://openalex.org/W1964200563', 'https://openalex.org/W1969900461', 'https://openalex.org/W2009252634', 'https://openalex.org/W2021657792', 'https://openalex.org/W2022061862', 'https://openalex.org/W2036077057', 'https://openalex.org/W2036318131', 'https://openalex.org/W2040944426', 'https://openalex.org/W2061609938', 'https://openalex.org/W2066200992', 'https://openalex.org/W2074128337', 'https://openalex.org/W2103722820', 'https://openalex.org/W2143374635', 'https://openalex.org/W2147186948', 'https://openalex.org/W2155922930', 'https://openalex.org/W2322876189'], 'related_works': ['https://openalex.org/W962565487', 'https://openalex.org/W2979244232', 'https://openalex.org/W2917354508', 'https://openalex.org/W2588492877', 'https://openalex.org/W2497443468', 'https://openalex.org/W2417741819', 'https://openalex.org/W2096124711', 'https://openalex.org/W2067214849', 'https://openalex.org/W2039688101', 'https://openalex.org/W2027564318'], 'abstract_inverted_index': {'In': [0, 20, 98], 'the': [1, 21, 38, 42, 46, 56, 81, 180, 190], 'current': [2], 'chapter,': [3, 100], 'digital': [4], 'morphometric': [5], 'analysis': [6], '(DMA)': [7], 'was': [8, 104, 117, 133], 'used': [9, 18, 34], 'to': [10, 35, 55, 106, 138, 154, 172, 188, 207, 212], 'quantify': [11], 'two': [12], 'markers': [13], 'of': [14, 23, 80, 88, 140, 182], 'biocompatibility': [15], 'around': [16], 'commonly': [17], 'biomaterials.': [19], 'field': [22], 'biomaterial': [24, 61], 'evaluation': [25], 'for': [26, 51, 109, 247], 'biocompatibility,': [27], 'more': [28], 'sophisticated': [29], 'methods': [30], 'are': [31, 63, 92], 'now': [32], 'being': [33, 93], 'precisely': [36], 'characterize': [37], 'elicited': [39], 'response': [40], 'from': [41, 230], 'surrounding': [43], 'tissue': [44], 'towards': [45], 'implanted': [47, 118], 'material.': [48], 'One': [49], 'reason': [50], 'this': [52, 85, 99], 'is': [53, 194], 'due': [54], 'fact': [57], 'that': [58, 193], 'many': [59, 79], 'newer': [60], 'innovations': [62], 'incorporating': [64], 'pharmaceutical': [65], 'agents': [66], '(e.g.,': [67], 'drug': [68, 72], 'eluting': [69, 73], 'stents': [70], 'and': [71, 90, 111, 123, 128, 148, 158, 201, 232], 'balloons).': [74], 'Therefore,': [75], 'as': [76, 184, 244], 'described': [77], 'in': [78, 84, 152], 'other': [82], 'chapters': [83], 'book,': [86], 'components': [87], 'toxicology': [89], 'pharmacology': [91], 'evaluated': [94, 124, 149], 'along': [95], 'with': [96, 135, 196, 238], 'biocompatibility.': [97, 221], 'expanded': [101], 'polytetrafluoroethylene': [102], '(ePTFE)': [103], 'compared': [105, 171], 'polypropylene': [107], '(PP)': [108], 'inflammatory': [110, 168, 191], 'foreign': [112], 'body': [113], 'response.': [114], 'Each': [115, 131], 'material': [116], 'into': [119], 'dorsal': [120], 'subcutaneous': [121], 'spaces': [122], 'after': [125], '2,': [126], '4,': [127], '12': [129], 'weeks.': [130], 'sample': [132], 'reacted': [134], 'an': [136], 'antibody': [137], 'cluster': [139], 'differentiation-68': [141], '(CD-68).': [142], 'The': [143, 222], 'resulting': [144], 'slides': [145], 'were': [146], 'scanned': [147], 'using': [150], 'DMA': [151, 183], 'order': [153], 'obtain': [155], 'accurate,': [156], 'reproducible,': [157], 'consistent': [159], 'results.': [160], 'Expanded': [161], 'PTFE': [162], 'demonstrated': [163], 'a': [164, 185, 197, 218], 'lower': [165], 'overall': [166], 'weighted': [167], 'score': [169, 192], 'when': [170], 'PP': [173], 'across': [174], 'all': [175], 'timepoints.': [176], 'This': [177], 'chapter': [178, 224], 'describes': [179, 226], 'use': [181, 208], 'novel': [186], 'approach': [187], 'measure': [189], 'associated': [195], 'specific': [198], 'biomaterial.': [199], 'Current': [200], 'future': [202], 'medical': [203], 'devices': [204], 'will': [205], 'need': [206], 'various': [209], 'analytical': [210], 'tools': [211, 246], 'comprehensively': [213], 'assess': [214], 'device,': [215], 'biomaterial,': [216], 'or': [217], 'combination': [219], "therapy's": [220], 'next': [223], 'further': [225], 'how': [227], 'quantitative': [228, 239], 'data': [229], 'histology': [231], 'immunohistochemistry': [233], 'assessments': [234], 'can': [235], 'be': [236], 'coupled': [237], 'polymerase': [240], 'chain': [241], 'reactions': [242], '(PCR)': [243], 'assessment': [245], 'product': [248], 'development.': [249]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2497443468', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-12-13T12:27:32.748600', 'created_date': '2016-08-23'}