Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2493740427', 'doi': 'https://doi.org/10.1158/1538-7445.am2016-lb-354', 'title': 'Abstract LB-354: Investigating potential molecular biomarkers for cetuximab response in metastatic colorectal cancer tissue using reverse phase protein array', 'display_name': 'Abstract LB-354: Investigating potential molecular biomarkers for cetuximab response in metastatic colorectal cancer tissue using reverse phase protein array', 'publication_year': 2016, 'publication_date': '2016-07-15', 'ids': {'openalex': 'https://openalex.org/W2493740427', 'doi': 'https://doi.org/10.1158/1538-7445.am2016-lb-354', 'mag': '2493740427'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2016-lb-354', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5017135640', 'display_name': 'Naser Monsefi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I142762351', 'display_name': 'Royal College of Surgeons in Ireland', 'ror': 'https://ror.org/01hxy9878', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I142762351']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Naser Monsefi', 'raw_affiliation_strings': ['1Royal College of Surgeons in Ireland, Dublin, Ireland;'], 'affiliations': [{'raw_affiliation_string': '1Royal College of Surgeons in Ireland, Dublin, Ireland;', 'institution_ids': ['https://openalex.org/I142762351']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029275456', 'display_name': 'Robert O’Byrne', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I142762351', 'display_name': 'Royal College of Surgeons in Ireland', 'ror': 'https://ror.org/01hxy9878', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I142762351']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Robert O’Byrne', 'raw_affiliation_strings': ['1Royal College of Surgeons in Ireland, Dublin, Ireland;'], 'affiliations': [{'raw_affiliation_string': '1Royal College of Surgeons in Ireland, Dublin, Ireland;', 'institution_ids': ['https://openalex.org/I142762351']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080071338', 'display_name': 'Steven Carberry', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I142762351', 'display_name': 'Royal College of Surgeons in Ireland', 'ror': 'https://ror.org/01hxy9878', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I142762351']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Steven Carberry', 'raw_affiliation_strings': ['1Royal College of Surgeons in Ireland, Dublin, Ireland;'], 'affiliations': [{'raw_affiliation_string': '1Royal College of Surgeons in Ireland, Dublin, Ireland;', 'institution_ids': ['https://openalex.org/I142762351']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025778865', 'display_name': 'Eugenia R. Zanella', 'orcid': 'https://orcid.org/0000-0002-8036-3789'}, 'institutions': [{'id': 'https://openalex.org/I55143463', 'display_name': 'University of Turin', 'ror': 'https://ror.org/048tbm396', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I55143463']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Eugenia R. Zanella', 'raw_affiliation_strings': ['2Department of Oncology, University of Turin Medical School, Turin, Italy;'], 'affiliations': [{'raw_affiliation_string': '2Department of Oncology, University of Turin Medical School, Turin, Italy;', 'institution_ids': ['https://openalex.org/I55143463']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066565774', 'display_name': 'Ana Barat', 'orcid': 'https://orcid.org/0000-0001-7164-5322'}, 'institutions': [{'id': 'https://openalex.org/I142762351', 'display_name': 'Royal College of Surgeons in Ireland', 'ror': 'https://ror.org/01hxy9878', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I142762351']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Ana Barat', 'raw_affiliation_strings': ['1Royal College of Surgeons in Ireland, Dublin, Ireland;'], 'affiliations': [{'raw_affiliation_string': '1Royal College of Surgeons in Ireland, Dublin, Ireland;', 'institution_ids': ['https://openalex.org/I142762351']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046521768', 'display_name': 'Mattia Cremona', 'orcid': 'https://orcid.org/0000-0003-3000-6246'}, 'institutions': [{'id': 'https://openalex.org/I142762351', 'display_name': 'Royal College of Surgeons in Ireland', 'ror': 'https://ror.org/01hxy9878', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I142762351']}, {'id': 'https://openalex.org/I2801846703', 'display_name': 'Beaumont Hospital', 'ror': 'https://ror.org/043mzjj67', 'country_code': 'IE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801846703']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Mattia Cremona', 'raw_affiliation_strings': ['3Department of Medical Oncology, Beaumont Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland.'], 'affiliations': [{'raw_affiliation_string': '3Department of Medical Oncology, Beaumont Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland.', 'institution_ids': ['https://openalex.org/I142762351', 'https://openalex.org/I2801846703']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067904174', 'display_name': 'Clare Morgan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I142762351', 'display_name': 'Royal College of Surgeons in Ireland', 'ror': 'https://ror.org/01hxy9878', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I142762351']}, {'id': 'https://openalex.org/I2801846703', 'display_name': 'Beaumont Hospital', 'ror': 'https://ror.org/043mzjj67', 'country_code': 'IE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801846703']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Clare Morgan', 'raw_affiliation_strings': ['3Department of Medical Oncology, Beaumont Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland.'], 'affiliations': [{'raw_affiliation_string': '3Department of Medical Oncology, Beaumont Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland.', 'institution_ids': ['https://openalex.org/I142762351', 'https://openalex.org/I2801846703']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004102701', 'display_name': 'Bryan T. Hennessy', 'orcid': 'https://orcid.org/0000-0002-7871-6477'}, 'institutions': [{'id': 'https://openalex.org/I142762351', 'display_name': 'Royal College of Surgeons in Ireland', 'ror': 'https://ror.org/01hxy9878', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I142762351']}, {'id': 'https://openalex.org/I2801846703', 'display_name': 'Beaumont Hospital', 'ror': 'https://ror.org/043mzjj67', 'country_code': 'IE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801846703']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Bryan T. Hennessy', 'raw_affiliation_strings': ['3Department of Medical Oncology, Beaumont Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland.'], 'affiliations': [{'raw_affiliation_string': '3Department of Medical Oncology, Beaumont Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland.', 'institution_ids': ['https://openalex.org/I142762351', 'https://openalex.org/I2801846703']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031287599', 'display_name': 'Andrea Bertotti', 'orcid': 'https://orcid.org/0000-0001-8196-7608'}, 'institutions': [{'id': 'https://openalex.org/I55143463', 'display_name': 'University of Turin', 'ror': 'https://ror.org/048tbm396', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I55143463']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Andrea Bertotti', 'raw_affiliation_strings': ['2Department of Oncology, University of Turin Medical School, Turin, Italy;'], 'affiliations': [{'raw_affiliation_string': '2Department of Oncology, University of Turin Medical School, Turin, Italy;', 'institution_ids': ['https://openalex.org/I55143463']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049302590', 'display_name': 'Livio Trusolino', 'orcid': 'https://orcid.org/0000-0002-6379-3365'}, 'institutions': [{'id': 'https://openalex.org/I55143463', 'display_name': 'University of Turin', 'ror': 'https://ror.org/048tbm396', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I55143463']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Livio Trusolino', 'raw_affiliation_strings': ['2Department of Oncology, University of Turin Medical School, Turin, Italy;'], 'affiliations': [{'raw_affiliation_string': '2Department of Oncology, University of Turin Medical School, Turin, Italy;', 'institution_ids': ['https://openalex.org/I55143463']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5075015717', 'display_name': 'Jochen H.M. Prehn', 'orcid': 'https://orcid.org/0000-0003-3479-7794'}, 'institutions': [{'id': 'https://openalex.org/I142762351', 'display_name': 'Royal College of Surgeons in Ireland', 'ror': 'https://ror.org/01hxy9878', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I142762351']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Jochen H.M. Prehn', 'raw_affiliation_strings': ['1Royal College of Surgeons in Ireland, Dublin, Ireland;'], 'affiliations': [{'raw_affiliation_string': '1Royal College of Surgeons in Ireland, Dublin, Ireland;', 'institution_ids': ['https://openalex.org/I142762351']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': '76', 'issue': '14_Supplement', 'first_page': 'LB', 'last_page': '354'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12867', 'display_name': 'Advanced Biosensing Techniques and Applications', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12867', 'display_name': 'Advanced Biosensing Techniques and Applications', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11016', 'display_name': 'Monoclonal and Polyclonal Antibodies Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation and Glycoproteins Research', 'score': 0.9916, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/panitumumab', 'display_name': 'Panitumumab', 'score': 0.4564221}, {'id': 'https://openalex.org/keywords/targeted-therapy', 'display_name': 'Targeted Therapy', 'score': 0.44833076}], 'concepts': [{'id': 'https://openalex.org/C2779998722', 'wikidata': 'https://www.wikidata.org/wiki/Q420296', 'display_name': 'Cetuximab', 'level': 4, 'score': 0.9729562}, {'id': 'https://openalex.org/C2781187634', 'wikidata': 'https://www.wikidata.org/wiki/Q20969980', 'display_name': 'KRAS', 'level': 4, 'score': 0.8810164}, {'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.7747332}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7373451}, {'id': 'https://openalex.org/C21790070', 'wikidata': 'https://www.wikidata.org/wiki/Q18030215', 'display_name': 'Neuroblastoma RAS viral oncogene homolog', 'level': 5, 'score': 0.7158872}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.64654475}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.556352}, {'id': 'https://openalex.org/C2779438470', 'wikidata': 'https://www.wikidata.org/wiki/Q424401', 'display_name': 'Epidermal growth factor receptor', 'level': 3, 'score': 0.50237155}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.49667817}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.45992336}, {'id': 'https://openalex.org/C2778332735', 'wikidata': 'https://www.wikidata.org/wiki/Q417775', 'display_name': 'Panitumumab', 'level': 5, 'score': 0.4564221}, {'id': 'https://openalex.org/C2781230642', 'wikidata': 'https://www.wikidata.org/wiki/Q492646', 'display_name': 'Targeted therapy', 'level': 3, 'score': 0.44833076}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.41997617}, {'id': 'https://openalex.org/C2781197716', 'wikidata': 'https://www.wikidata.org/wiki/Q864574', 'display_name': 'Biomarker', 'level': 2, 'score': 0.41163394}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.2858345}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.27288806}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.18232143}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2016-lb-354', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.85, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W93307583', 'https://openalex.org/W3149695606', 'https://openalex.org/W3116599757', 'https://openalex.org/W2792885295', 'https://openalex.org/W2766095861', 'https://openalex.org/W2266896604', 'https://openalex.org/W2133128087', 'https://openalex.org/W2088713834', 'https://openalex.org/W2058934913', 'https://openalex.org/W1968430623'], 'abstract_inverted_index': {'Abstract': [0], 'Colorectal': [1], 'cancer': [2, 12, 229, 396], '(CRC)': [3], 'is': [4], 'the': [5, 18, 27, 31, 41, 120, 287, 352, 407, 412], 'third': [6], 'and': [7, 15, 17, 102, 143, 197, 254, 269, 315, 334], 'second': [8, 19], 'most': [9, 20], 'commonly': [10], 'diagnosed': [11], 'in': [13, 26, 53, 82, 95, 158, 186, 211, 266, 326, 357, 393], 'males': [14], 'females,': [16], 'common': [21], 'cause': [22], 'of': [23, 33, 43, 55, 114, 161, 224, 237, 282, 305, 312, 354, 406, 411], 'cancer-related': [24], 'deaths': [25], 'developed': [28], 'world.': [29], 'Identifying': [30], 'importance': [32], 'epidermal': [34], 'growth': [35], 'factor': [36], '(EGF)': [37], 'signalling': [38, 318], 'pathways': [39], 'for': [40, 155, 299, 390, 415], 'survival': [42, 81], 'CRC': [44, 63, 83, 167], 'cells': [45], '(Van': [46, 85], 'Cutsem,': [47, 86], 'Kohne': [48, 87], 'et': [49, 88, 108, 136, 194], 'al.': [50, 89, 109, 137, 195], '2011)': [51], 'resulted': [52], 'development': [54], 'therapies': [56, 77, 145], 'that': [57, 140, 347], 'target': [58], 'EGF-receptors': [59], '(EGFR).': [60], 'Late': [61], 'stage': [62], 'patients': [64, 84, 96, 115], 'are': [65, 92, 146], 'mainly': [66], 'treated': [67], 'with': [68, 97, 174, 221, 331], 'monoclonal': [69], 'anti-EGFR': [70, 76, 122], 'antibodies': [71, 226], 'such': [72, 248], 'as': [73, 201, 232, 249, 296], 'cetuximab.': [74, 178], 'Although': [75], 'have': [78, 127, 322], 'significantly': [79, 263], 'improved': [80], '2009),': [90], 'they': [91], 'not': [93, 117], 'effective': [94], 'activating': [98], 'KRAS,': [99], 'BRAF,': [100], 'NRAS': [101], 'PI3KCA': [103], 'mutations': [104], '(De': [105, 132], 'Roock,': [106, 133], 'Claes': [107], '2010).': [110], 'Nevertheless,': [111], 'between': [112, 243, 279], '50-60%': [113], 'will': [116, 336, 348], 'benefit': [118], 'from': [119, 169], 'additional': [121], 'treatment,': [123], 'even': [124], 'when': [125], 'these': [126, 283, 306], 'a': [128, 159, 215, 222, 275, 291, 309, 341], 'quadruple': [129, 163], 'wild-type': [130], 'status': [131], 'De': [134], 'Vriendt': [135], '2011),': [138], 'suggesting': [139], 'novel': [141], 'biomarkers': [142, 154, 298, 389], 'targeted': [144], 'required.': [147], 'In': [148], 'this': [149], 'study,': [150], 'we': [151, 273], 'investigate': [152], 'potential': [153, 293, 387], 'cetuximab': [156, 190, 258, 300, 332, 355, 391], 'response': [157, 333, 392], 'panel': [160, 223], '93': [162], 'wild-type,': [164], 'liver': [165], 'metastatic': [166, 394], 'samples': [168], 'patient': [170, 329], 'derived': [171], 'xenografts': [172], '(PDX)': [173], 'known': [175], 'responses': [176], 'to': [177, 183, 294, 339, 350], 'Matching': [179], 'PDXs': [180], 'were': [181, 198, 209, 262], 'used': [182, 338], 'measure': [184], 'changes': [185], 'tumour': [187], 'volumes': [188], 'post': [189, 257], 'treatment': [191], '(Bertotti,': [192], 'Papp': [193], '2015)': [196], 'later': [199], 'categorised': [200], 'regressing,': [202], 'progressing': [203], 'or': [204], 'stabilised.': [205], 'Protein': [206], 'expression': [207, 246, 280], 'levels': [208, 281], 'measured': [210, 238], 'matched': [212], 'PDXs,': [213], 'using': [214, 398], 'reverse': [216, 399], 'phase': [217, 400], 'protein': [218, 245, 401], 'array': [219], '(RPPA)': [220], '72': [225], 'targeting': [227], 'key': [228], 'related': [230], 'proteins': [231, 261, 284, 307], 'previously': [233], 'described).': [234], 'Statistical': [235], 'analysis': [236], 'values': [239], 'showed': [240, 308], 'significant': [241, 310], 'correlation': [242, 278], 'high': [244, 276], 'levels,': [247], 'Chk-1,': [250], 'PARP,': [251], 'HIAP-2': [252], '(cIAP-1),': [253], 'PDX': [255], 'progression': [256], 'treatment.': [259], 'These': [260, 320], 'expressed': [264], 'lower': [265], 'both': [267], 'regressing': [268], 'stable': [270], 'PDXs.': [271], 'Interestingly,': [272], 'found': [274], 'cross': [277], 'across': [285], 'all': [286], 'samples,': [288], 'giving': [289], 'them': [290], 'great': [292], 'act': [295], 'predictive': [297], 'response.': [301], 'Bioinformatics': [302], 'pathway': [303], 'enrichment': [304, 311], 'intrinsic': [313], 'apoptotic': [314], 'cell': [316, 344], 'cycle': [317, 345], 'pathways.': [319], 'results': [321], 'also': [323], 'been': [324], 'investigated': [325], 'publically': [327], 'available': [328], 'data': [330], 'together': [335], 'be': [337], 'construct': [340], 'deterministic': [342], 'mathematical': [343], 'model': [346], 'help': [349], 'predict': [351], 'outcome': [353], 'therapy': [356], 'future.': [358], 'Citation': [359], 'Format:': [360], 'Naser': [361], 'Monsefi,': [362], 'Robert': [363], 'O’Byrne,': [364], 'Steven': [365], 'Carberry,': [366], 'Eugenia': [367], 'R.': [368], 'Zanella,': [369], 'Ana': [370], 'Barat,': [371], 'Mattia': [372], 'Cremona,': [373], 'Clare': [374], 'Morgan,': [375], 'Bryan': [376], 'T.': [377], 'Hennessy,': [378], 'Andrea': [379], 'Bertotti,': [380], 'Livio': [381], 'Trusolino,': [382], 'Jochen': [383], 'H.M.': [384], 'Prehn.': [385], 'Investigating': [386], 'molecular': [388], 'colorectal': [395], 'tissue': [397], 'array.': [402], '[abstract].': [403], 'In:': [404], 'Proceedings': [405], '107th': [408], 'Annual': [409], 'Meeting': [410], 'American': [413], 'Association': [414], 'Cancer': [416, 427], 'Research;': [417], '2016': [418], 'Apr': [419], '16-20;': [420], 'New': [421], 'Orleans,': [422], 'LA.': [423], 'Philadelphia': [424], '(PA):': [425], 'AACR;': [426], 'Res': [428], '2016;76(14': [429], 'Suppl):Abstract': [430], 'nr': [431], 'LB-354.': [432]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2493740427', 'counts_by_year': [], 'updated_date': '2024-12-12T01:21:05.794509', 'created_date': '2016-08-23'}