Title: Radioimmunoassay of tricyclic antidepressants
Abstract: The tricyclic antidepressant drugs (TCA) are widely used in the treatment of depression. Since there are marked interindividual differences in the steady state concentrations of a TCA in plasma, the monitoring of the plasma concentrations as a guide to effective dosage has been developed. There are indications that both high and low concentrations of nortriptyline (NT), for example, are associated with poor clinical responses (Åsberg, 1974; Kragh-Sørensen et al., 1976), while the response may increase linearly with the plasma concentrations of imipramine and amitriptyline (AMI) (Gram, 1980).
Publication Year: 1981
Publication Date: 1981-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
Access and Citation
Cited By Count: 4
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