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343, 357], 'distant': [25], 'is': [27, 37], 'surgical': [28], 'resection': [29], 'any': [31], 'additional': [32], 'chemotherapy.': [33], 'However,': [34], 'tumor': [35, 61, 239, 366, 393], 'recurrence': [36, 62, 115, 148, 214, 218, 240, 290, 326, 367, 397], 'occurred': [38], 'in': [39, 95, 155, 177, 194, 209, 241, 255, 260, 303, 352, 392], 'approximately': [40], '20%': [41], 'of': [42, 63, 82, 138, 246, 280, 328, 368, 390, 399, 407, 412], 'these': [43, 247], 'patients': [44, 111, 113, 118, 125, 131, 332], 'after': [45], 'curative': [46], 'resection.': [47], 'To': [48], 'date,': [49], 'there': [50], 'were': [51, 84, 108, 163, 205, 341], 'no': [52], 'biomarkers': [53], 'detecting': [55, 90], 'high': [57, 92, 243, 278, 334], 'risk': [58, 93], 'group': [59, 94, 245, 259], 'CRC.': [66, 98, 371], 'In': [67, 199, 317], 'present': [69], 'study,': [70, 123, 202], 'miRNAs': [71, 139, 145, 162, 204, 248], 'extracted': [72, 170, 190], 'from': [73, 171, 191], 'both': [74], 'frozen': [75, 172, 265, 356], 'tissues': [76, 81], 'formalin-fixed': [78], 'paraffin-embedded': [79], '(FFPE)': [80], 'CRC': [83, 107, 331, 353], 'investigated': [85], 'a': [87, 150, 361, 396], 'candidate': [88, 144, 161], 'Methods:': [99], 'Patients': [100], 'with': [101, 114, 147, 213, 333], 'histologically': [102], 'confirmed': [103], 'as': [104, 224, 284, 395], 'enrolled;': [109], '10': [110], '(5': [112], '5': [117], 'recurrence)': [120], 'preliminary': [122, 157, 201], '80': [124], 'training': [127, 179, 262, 305], 'cohort,': [128], '57': [130], 'validation': [133, 196, 319], 'cohort.': [134, 180, 197], 'First,': [135], 'comprehensive': [136], 'analysis': [137, 273], 'was': [140, 183, 249, 282, 301], 'performed': [141], 'to': [142, 271], 'select': [143], 'associated': [146], 'using': [149, 168, 188, 264, 307, 321], 'high-sensitivity': [151], 'miRNA': [152, 169, 189], 'array': [153], 'chip': [154], 'study.': [158, 228], 'Next,': [159], 'analyzed': [164], 'by': [165, 185], 'real-time': [166, 186], 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