Publication Information

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1725], 'realize': [150], 'its': [151, 219, 339, 398, 777, 837, 902, 1145, 1240, 1296], 'full': [152, 637], 'potential—at': [153], 'individual': [155, 968, 995, 1597, 1929], 'level': [156, 165], 'diagnosis': [158, 354], 'treatment,': [160, 314], 'promotion': [168], 'disease': [170, 310, 418, 675], 'prevention—risks': [171], 'benefits': [173, 196, 956, 1782, 1857], 'must': [174, 251], 'be': [175, 198, 287, 358, 479, 528, 631, 738, 795, 946, 1338, 1495, 1695, 1716, 1722], 'shared': [176], 'across': [177, 1442], 'societal': [178, 993], 'groups,': [179, 203, 431, 752, 1448, 1524], 'key': [181], 'principle': [182], 'distributive': [184, 1663], 'justice.': [185], 'Without': [186, 1786], 'careful': [187], 'attention': [188, 254], 'structure': [191], 'design': [193], 'studies,': [195, 267], 'may': [197, 357, 478, 526, 735, 794, 1712, 1800], 'realized': [199], 'by': [200, 982, 1174], 'only': [201, 565, 1337, 1759], 'select': [202], 'exacerbating': [204], 'current': [205, 233], 'disparities.4.Mersha': [207], 'T.B.': [208, 328, 387, 766, 826, 891, 1229, 1285], 'Abebe': [209, 329, 388, 767, 827, 892, 1230, 1286], 'T.': [210, 330, 389, 768, 828, 893, 1231, 1287], 'Self-reported': [211, 331, 390, 769, 829, 894, 1232, 1288], 'race/ethnicity': [212, 332, 391, 770, 830, 895, 1176, 1233, 1289], 'age': [215, 335, 394, 773, 833, 898, 1026, 1096, 1236, 1292], 'genomic': [217, 337, 376, 396, 775, 835, 900, 1056, 1238, 1273, 1294, 1317, 1325], 'research:': [218, 338, 397, 776, 836, 901, 1239, 1295], 'potential': [220, 340, 399, 778, 838, 903, 1241, 1297, 1332, 1351], 'impact': [221, 341, 400, 779, 839, 904, 1242, 1266, 1298], 'understanding': [223, 343, 402, 781, 841, 906, 1244, 1300, 1590], 'disparities.10.1186/s40246-014-0023-xHum': [225, 345, 404, 783, 843, 908, 1246, 1302], 'Genomics.': [226, 346, 405, 784, 844, 909, 1247, 1303], '9:': [228, 348, 407, 786, 846, 911, 1249, 1305], '1Google': [229, 349, 408, 787, 847, 912, 1250, 1306], 'In': [231, 1918], 'climate': [234], 'accelerating': [236], 'medicine,': [238], 'how': [239, 696, 1491, 1591, 1659], 'measure': [241], 'achieve': [243, 1473, 1778], 'genetic,': [244], 'environmental,': [245], 'diversity': [248, 264, 291, 638, 1446, 1476, 1493, 1707, 1795], 'participants': [250, 868, 1352, 1592], 'receive': [252, 1596], 'it': [255, 1043, 1078, 1840], 'requires.': [256], '(Although': [257], 'we': [258], 'focus': [259, 274, 507], 'here': [260], 'insuring': [262], 'precision-medicine': [266, 1483, 1690, 1798], 'as': [268, 297, 750, 754, 1066, 1223, 1769, 1771], 'number': [270, 533, 791, 1213], 'studies': [272, 300, 369, 564, 597, 864, 1057, 1138, 1443], 'variables': [279, 296], 'increases,': [280], 'many': [281], 'issues': [284], 'identified': [285, 883], 'will': [286, 717, 945, 1494, 1628, 1877], 'relevant': [288, 542], 'achieving': [290], 'exposure': [293], 'those': [295, 672, 887, 1420, 1813], 'well).': [298], 'Precision-medicine': [299, 596], 'designed': [302], 'identify': [304, 1331], 'variants': [306, 420, 462, 522, 884], 'contribute': [308], 'risk': [311, 419, 598, 1061], 'or': [312, 482, 1282, 1535], 'affect': [313, 455, 1713], 'frequencies': [316], 'which': [318, 378, 614, 1711, 1728], 'differ': [319, 721], 'substantially': [320], 'within': [321, 1388, 1462], '(and': [322], 'across)': [323], 'populations': [324, 363, 426, 684], 'varying': [326], 'ancestries.4.Mersha': [327], 'However,': [351], 'improvements': [352], 'treatment': [356], 'distributed': [359], 'unevenly,': [360], 'with': [361, 536, 647, 673, 685, 704, 807, 816, 1572], 'majority': [362], 'benefiting': [364], 'higher': [366, 686, 760], 'proportions': [367, 818], 'if': [368], 'data': [373, 413, 851, 873, 924, 1007, 1421, 1455, 1773], 'from': [374, 382, 724, 1262, 1620], 'existing': [375, 850, 1321], 'databases,': [377], 'predominantly': [379, 867], 'contain': [380, 1324], 'samples': [381, 544, 793, 1418], 'persons': [383, 755], 'European': [385, 425, 727, 856, 889], 'ancestry.4.Mersha': [386, 825], 'Studies': [410, 1908, 1942], 'such': [412, 521, 753, 1222], 'likely': [415, 629], 'miss': [417], 'rare': [423], 'among': [424, 429, 470, 886], 'but': [427, 1482, 1633, 1805], 'common': [428, 469], 'other': [430, 490, 1703], 'distort': [434], 'effect': [435], 'size': [436], 'estimates.5.Bustamante': [437], 'C.D.': [438, 581], 'Burchard': [439, 582], 'E.G.': [440, 583], 'De': [441, 584], 'la': [442, 585], 'Vega': [443, 586], 'F.M.': [444, 587], 'Genomics': [445, 588], 'world.1:CAS:528:DC%2BC3MXovFegtrw%3D10.1038/475163aNature.': [448, 591], '2011;': [449, 592], '475:': [450, 593], '163-165Google': [451, 594], 'Similar': [453, 801], 'considerations': [454, 802], 'medication': [456], 'responses:': [457], 'example,': [459, 1153], 'some': [460, 751, 858, 1137, 1523], 'related': [463, 1169], 'metabolism': [466], 'more': [468], 'individuals': [471], 'African': [473, 537, 757, 824, 1527], 'ancestry.': [474], 'That': [475], 'is,': [476], 'there': [477], 'increased': [480], 'sensitivity': [481], 'diminished': [483], 'response': [484, 504], 'β-agonists,': [486], 'warfarin,': [487], 'chemotherapy,': [488], 'medications.6.Yasuda': [491], 'S.U.': [492], 'Huang': [495], 'S.M.': [496, 1191], 'The': [497, 518, 608, 960, 1502, 1859], 'role': [498], 'ethnicity': [500, 1405], 'variability': [502], 'drugs:': [506], 'clinical': [509, 1954], 'pharmacology': [510], 'studies.1:CAS:528:DC%2BD1cXhtVShtr%2FP10.1038/clpt.2008.141Clin': [511], '2008;': [514], '84:': [515], '417-423Google': [516], 'dosing': [524], 'not': [527, 556, 737, 927, 999, 1806], 'understood': [529], 'until': [530, 1822], 'sufficient': [532, 648, 1459], 'people': [535, 854], 'ancestry': [538, 723, 811, 1023, 1093, 1268, 1414], 'included': [540], 'study': [543, 627, 1538, 1588, 1600, 1623], 'account': [546, 1373], 'within-group': [548, 689, 763], 'between-group': [550], 'variabilities.': [551], 'This': [552, 914, 1754], 'selection': [553], 'problem': [554], 'new.': [557], 'Scientists': [558], 'completed': [560], 'analyzed': [562], 'seminal': [563], 'discover': [567], 'proportion': [570], 'minorities': [572], 'enrolled': [573], 'was': [574, 1943], 'too': [575], 'small': [576], 'meaningful': [578, 621, 651, 747, 1546], 'subgroup': [579], 'analysis.5.Bustamante': [580], 'similar': [600], 'fate': [601], 'unless': [602, 1320], 'three': [603], 'major': [604], 'challenges': [605], 'addressed.': [607], 'first': [609], 'challenge': [610, 962, 1504], 'deciding': [612, 695], 'prospectively': [613], 'groups': [615, 677, 719, 731, 744, 944], 'include': [617, 671, 1397, 1637], 'ensure': [619, 1445], 'degree': [622], 'diversity.': [624, 691], 'No': [625], 'single': [626, 657], 'large': [632, 1348], 'enough': [633], 'encompass': [635, 718], 'United': [641, 974], 'States,': [642], 'much': [643], 'less': [644], 'world,': [646], 'power': [649], 'findings': [652], 'emerge,': [654], 'no': [656, 1862], 'approach': [658, 933, 1395, 1471], 'right': [660], 'all': [662, 742, 1311, 1823], 'studies.': [663, 1501], 'Options': [664], 'consist': [665], 'oversampling': [667, 917], 'various': [668], 'groups.': [669], 'Examples': [670], 'greater': [674], 'burdens,': [676], 'been': [680, 919, 929, 1220, 1533, 1549], 'historically': [681], 'underrepresented,': [682], 'levels': [687, 761], 'Each': [692], 'choice': [693], 'involves': [694, 963], 'best': [697, 1470, 1660], 'balance': [699], 'redress': [700], 'past': [702], 'wrongs': [703], 'important,': [705], 'ongoing': [706], 'population-based': [707], 'science.': [708], 'Given': [709], 'realities': [711], 'American': [713, 810], 'society,': [714], 'these': [715, 1051, 1113, 1334, 1434, 1825], 'decisions': [716], 'Americans': [725, 806, 1528], 'descent.': [728], 'Although': [729], 'probably': [732], 'overlap,': [733], 'investigators': [734, 1486], 'still': [736, 1478], 'able': [739], 'sample': [741, 866, 1366], 'eligible': [743], 'adequately': [745], 'analysis.': [748], 'Insofar': [749], 'descent,': [758], 'diversity,4.Mersha': [765], 'larger': [790], 'required': [796], 'generate': [798], 'significant': [799, 923], 'findings.': [800], 'arise': [803], 'Mexican': [805], '35–64%': [808], 'Native': [809, 821, 1530], 'Hispanics': [813], 'Latinos': [815], 'variable': [817], 'European,': [820], 'American,': [822], 'Because': [849, 1512], 'sets': [852], 'overrepresent': [853], 'ancestry,': [857], 'scientists': [859], 'suggested': [861], 'newer': [863], 'should': [865, 1487, 1694], 'color': [870], 'provide': [872, 922], 'accurate': [876], 'assessment': [877], 'pathogenicity': [879], 'penetrance': [881], 'uncommon': [885], 'descent.4.Mersha': [890], 'type': [915], 'has': [918], 'shown': [920], 'would': [926, 1121, 1593], 'obtained': [930], 'otherwise.': [931], 'Whatever': [932], 'selected,': [935], 'additional': [936, 1060, 1542], 'efforts': [937], 'involve': [939], 'genetically': [940], 'socially': [942], 'diverse': [943], 'necessary': [947], 'satisfy': [949], 'desideratum': [951], 'fairly': [953], 'distributing': [954], 'medicine.': [959, 1785], 'second': [961], 'selecting': [964], 'appropriate': [965], 'criteria': [966, 1361], 'inclusion.': [969], 'Current': [970], 'approaches': [971], 'States': [975], 'emphasize': [976], 'self-reported': [977, 1118, 1217, 1402], 'race,': [978], 'using': [979], 'categories': [980, 1054, 1120], 'developed': [981, 1550], 'Office': [984], 'Management': [986], 'Budget.': [988], 'Self-report,': [989], 'however,': [990, 1310, 1541], 'largely': [991], 'reflects': [992], 'constructions': [996], 'identity,': [998], 'variation': [1002, 1154, 1387], '(although': [1006], 'about': [1008], 'conflicting).7.Shim': [1011], 'J.K.': [1012, 1082], 'Ackerman': [1013, 1083], 'S.L.': [1014, 1084], 'Darling': [1015, 1085], 'K.W.': [1016, 1086], 'Hiatt': [1017, 1087], 'R.A.': [1018, 1088], 'Lee': [1019, 1089], 'S.S.': [1020, 1090], 'Race': [1021, 1091], 'inclusion:': [1028, 1098], 'technique': [1029, 1099], 'meaning': [1031, 1101], 'post-genomic': [1033, 1103], 'science.10.1177/0022146514555224J': [1034, 1104], 'Soc': [1036, 1106], 'Behav.': [1037, 1107], '2014;': [1038, 1108], '55:': [1039, 1109], '504-518Google': [1040, 1110], 'Moreover,': [1042], 'important': [1045], 'recognize': [1047], 'relying': [1049], 'traditional': [1052], 'carries': [1058], 'reification': [1063], 'race': [1065, 1119, 1218, 1380, 1403], 'concept,': [1069], 'face': [1072], 'growing': [1075, 1556], 'consensus': [1076], 'conceptually': [1080], 'incoherent.7.Shim': [1081], 'Despite': [1112], 'limitations': [1114], 'risks,': [1116], 'eliminating': [1117], 'reduce': [1122], 'our': [1123, 1134, 1382], 'ability': [1124], 'discern': [1126], 'consequences': [1129, 1147], 'status': [1132, 1143], 'society.': [1135], 'Furthermore,': [1136], 'perceived': [1141], 'possible': [1149], 'biologic': [1150], 'implications,': [1151], 'DNA': [1156], 'methylation8.King': [1157], 'K.': [1158], 'Murphy': [1159], 'Hoyo': [1161], 'C.': [1162], 'Epigenetic': [1163], 'regulation': [1164], "Newborns'": [1166], 'imprinted': [1167], 'genes': [1168], 'gestational': [1171], 'growth:': [1172], 'patterning': [1173], 'parental': [1175], 'maternal': [1178], 'socioeconomic': [1179, 1709], 'status.10.1136/jech-2014-204781J': [1180], 'Epidemiol': [1181], 'Community': [1182], 'Health.': [1183], '69:': [1185], '639-647Google': [1186], 'telomere': [1189, 1201], 'length.9.Lynch': [1190], 'Peek': [1192], 'M.K.': [1193], 'Mitra': [1194], 'N.': [1195], 'Race,': [1196], 'ethnicity,': [1197], 'psychosocial': [1198], 'length': [1202], 'multicenter': [1205], 'setting.10.1371/journal.pone.0146723PLoS': [1206], 'One.': [1207], '2016;': [1208, 1916, 1971], '11:': [1209], 'e0146723Google': [1210], 'A': [1212], 'alternatives': [1215], 'suggested,': [1221], 'use': [1225, 1400], 'markers,4.Mersha': [1228], 'admixture': [1252, 1270], 'analysis,10.Kidd': [1253], 'J.M.': [1254], 'Gravel': [1255], 'Byrnes': [1257], 'Population': [1259], 'inference': [1261], 'personal': [1263], 'genome': [1264], 'data:': [1265], 'human': [1272], 'variation.1:CAS:528:DC%2BC38XhsVKqs7fF10.1016/j.ajhg.2012.08.025Am': [1274], 'Hum': [1276], 'Genet.': [1277], '91:': [1279], '660-671Google': [1280], 'ancestry-informative': [1283], 'regions.4.Mersha': [1284], 'These': [1308], 'approaches,': [1309], 'depend': [1312], 'analysis': [1315, 1344, 1461], 'data.': [1318], 'Thus,': [1319], 'databases': [1322], 'information': [1326], 'being': [1328], 'used': [1329], 'participants,': [1333], 'measures': [1335, 1846], 'can': [1336, 1702], 'applied': [1339], 'after': [1340], 'enrollment': [1341, 1408, 1571], 'occurred.': [1346], 'Discarding': [1347], 'numbers': [1349], 'post': [1355], 'facto': [1356], 'failure': [1357], 'meet': [1359], 'stratification': [1363], 'expensive': [1368], 'arguably': [1370], 'wasteful.': [1371], 'To': [1372], 'both': [1375, 1834], 'effects': [1378], 'society': [1383], 'between': [1390, 1464, 1764], 'ancestries,': [1391], 'reasonable': [1393], 'interim': [1394, 1845], 'might': [1396], 'following:': [1399], 'initial': [1407], 'markers': [1412, 1721, 1729], 'adjust': [1416], 'when': [1419, 1745], 'become': [1422], 'available;': [1423], 'iterative': [1424], 'updating': [1425], 'recruitment': [1427, 1739], 'targets': [1428], 'outreach': [1430, 1507], 'combined': [1435], 'measures;': [1436], 'coordination': [1438], 'sampling': [1440], 'thus': [1449], 'ensuring': [1450], 'adequate': [1451], 'representation': [1452], 'robust': [1454], 'quantity': [1458], 'subgroups.': [1465], 'Whether': [1466], 'desired': [1475], 'an': [1479, 1514, 1925], 'open': [1480], 'question,': [1481], 'funders': [1484], 'establish': [1488], 'priori': [1490], 'defined': [1496], 'measured': [1498], 'their': [1500], 'third': [1503], 'designing': [1506], 'targeted': [1510], 'populations.': [1511, 1574], 'egregious': [1515], 'history': [1516], 'exclusion': [1518], 'exploitation': [1520], 'research,': [1522], 'most': [1525], 'notably': [1526], 'Americans,': [1531], 'absent': [1534], 'underrepresented': [1536], 'samples.': [1539], 'Recently,': [1540], 'opportunities': [1543], 'respectful,': [1545], 'participation': [1547], 'contributed': [1553], 'body': [1557], 'literature': [1559], 'includes': [1561], 'successful': [1562], 'promising': [1564], 'methods': [1565, 1602], 'increase': [1567], 'partnership,': [1568], 'engagement,': [1569], 'minority': [1573], 'Among': [1575], 'proven': [1579], 'early': [1582], 'involvement': [1583], 'planning': [1585], 'defining': [1587], 'goals;': [1589], 'like': [1594], 'aggregate': [1599], 'results;': [1601], 'facilitate': [1604], 'two-way': [1605], 'communication,': [1606], 'including': [1607], 'overcoming': [1608], 'language': [1609], 'barriers;': [1610], 'long-term': [1612], 'commitment': [1613], 'well-being': [1616], 'inception': [1621], 'completion': [1624], 'beyond.': [1626], 'Approaches': [1627], 'vary': [1629], 'different': [1631], 'contexts,': [1632], 'need': [1635], 'thoughtful': [1638], 'community': [1641], 'engagement': [1642], 'research': [1644], 'planning,': [1645], 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