Abstract: Most clinical trials and surveys either ignore response shift or assume it is negligible. In randomised trials this may sometimes be reasonable. But response shift becomes more of a threat when trials are unblinded, although even then there is the temptation to take the pragmatic view that many forms of response shift, such as adaptation to illness, are consequences of the overall policy of management. This chapter discusses when and how response shift and other forms of bias, such as recall bias and selective reporting, might affect the analyses or distort the interpretation of results. It chapter examines biases that affect questionnaire assessments and, in particular response shift. The chapter illustrates examples in which response-shift effects appear to have played an important role. Responses to items on a PRO questionnaire can be influenced by a patient's current mood, response acquiescence, faking good tendency, or central tendency bias.
Publication Year: 2015
Publication Date: 2015-12-05
Language: en
Type: other
Indexed In: ['crossref']
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Cited By Count: 1
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