Ketamine and other NMDA receptor antagonists

Name: Work Video:
Duration: 3 min 30 s
Description: Ketamine is a non-competitive N-methyl D-aspartate (NMDA) receptor antagonist and is most effective in pain states where hyper-excitability is established Ketamine undergoes first-pass metabolism to norketamine, which is a more potent analgesic than ketamine. This can explain why oral ketamine is more potent than parenteral ketamine...
Marie Fallon; Cameron Fergus; Barry Laird
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