Title: Formation and function of modified nucleosides in bacterial transfer RNA
Abstract: Synthesis of tRNA in most organisms occurs by step-wise processing of mono- or polycistronic precursor molecules. Other steps during the maturation process involve several highly specific enzymes that catalyze the formation of modified nucleosides of which more than 50 have so far been characterized. Such nucleosides are derivatives of the ordinary constituents of the tRNA, adenosine, guanosine, uridine and cytidine. All known modification reactions occur on the polynucleotide level, except for the synthesis of the Q-base, which can be inserted instead of a guanosine in the wobble position of some tRNA species (Nishimura, 1980).KeywordsAromatic Amino AcidShikimic AcidModification ReactiontRNA MoleculeAnticodon LoopThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Publication Year: 1982
Publication Date: 1982-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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Cited By Count: 1
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