Title: A Practical Guide to Protein Structure Prediction
Abstract: AbstractThe protein-folding problem is one of the greatest remaining challenges in structural molecular biology (if not the whole of biology). How do proteins translate from their primary structure (sequence) to tertiary structure? How is the information encoded? Basically, how do proteins fold? Often, the protein-folding problem is seen as a computational problem—do we know enough about the rules of protein structure to program a computer to read in a protein sequence and output a correct tertiary structure? Aside from the academic interest in understanding the physics and chemistry of protein folding, why are so many people interested in finding an algorithm (i.e., a method) for predicting the native structure of a protein given just its sequence?KeywordsProtein Structure PredictionFold RecognitionFolding SimulationCASP2 ExperimentSequence DatabankThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Publication Year: 2003
Publication Date: 2003-11-15
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 10
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