Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2470169071', 'doi': 'https://doi.org/10.3760/cma.j.issn.0578-1426.2016.01.009', 'title': '[The correlation between HLA-DR or CD38 expression in CD8(+)T cells and CD4(+)T cells count in treatment-naive HIV/AIDS patients].', 'display_name': '[The correlation between HLA-DR or CD38 expression in CD8(+)T cells and CD4(+)T cells count in treatment-naive HIV/AIDS patients].', 'publication_year': 2016, 'publication_date': '2016-01-01', 'ids': {'openalex': 'https://openalex.org/W2470169071', 'doi': 'https://doi.org/10.3760/cma.j.issn.0578-1426.2016.01.009', 'mag': '2470169071', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26796651'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26796651', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102557144', 'display_name': 'Jing Xie', 'orcid': 'https://orcid.org/0009-0004-8556-2295'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jing Xie', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025546736', 'display_name': 'Zhifeng Qiu', 'orcid': 'https://orcid.org/0000-0002-7076-4343'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Zhifeng Qiu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101886173', 'display_name': 'Yang Han', 'orcid': 'https://orcid.org/0000-0002-4143-7765'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yang Han', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100363314', 'display_name': 'Yanling Li', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yanling Li', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5115591531', 'display_name': 'Xiaojing Song', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xiaojing Song', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5044459845', 'display_name': 'Taisheng Li', 'orcid': 'https://orcid.org/0000-0002-7050-5675'}, 'institutions': [{'id': 'https://openalex.org/I2801228662', 'display_name': 'Peking Union Medical College Hospital', 'ror': 'https://ror.org/04jztag35', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801228662']}, {'id': 'https://openalex.org/I200296433', 'display_name': 'Chinese Academy of Medical Sciences & Peking Union Medical College', 'ror': 'https://ror.org/02drdmm93', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I200296433']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Taisheng Li', 'raw_affiliation_strings': ['Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.', 'institution_ids': ['https://openalex.org/I2801228662', 'https://openalex.org/I200296433']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.25, 'has_fulltext': False, 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.55, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': '55', 'issue': '1', 'first_page': '36', 'last_page': '9'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9926, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 0.9925, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C159912055', 'wikidata': 'https://www.wikidata.org/wiki/Q14885119', 'display_name': 'CD38', 'level': 4, 'score': 0.8549988}, {'id': 'https://openalex.org/C167672396', 'wikidata': 'https://www.wikidata.org/wiki/Q417800', 'display_name': 'CD8', 'level': 3, 'score': 0.7145656}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.596684}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.56353956}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.51240546}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.48423147}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.48140526}, {'id': 'https://openalex.org/C139563560', 'wikidata': 'https://www.wikidata.org/wiki/Q224930', 'display_name': 'Natural killer T cell', 'level': 4, 'score': 0.45729718}, {'id': 'https://openalex.org/C148125776', 'wikidata': 'https://www.wikidata.org/wiki/Q1622348', 'display_name': 'CD28', 'level': 4, 'score': 0.4386868}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4036993}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.39411145}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.27960753}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.09561473}, {'id': 'https://openalex.org/C10205521', 'wikidata': 'https://www.wikidata.org/wiki/Q4035578', 'display_name': 'CD34', 'level': 3, 'score': 0.077408165}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.058094323}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D051997', 'descriptor_name': 'ADP-ribosyl Cyclase 1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000163', 'descriptor_name': 'Acquired Immunodeficiency Syndrome', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D006684', 'descriptor_name': 'HLA-DR Antigens', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016176', 'descriptor_name': 'T-Lymphocyte Subsets', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D051997', 'descriptor_name': 'ADP-ribosyl Cyclase 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000163', 'descriptor_name': 'Acquired Immunodeficiency Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018791', 'descriptor_name': 'CD4 Lymphocyte Count', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016022', 'descriptor_name': 'Case-Control Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006684', 'descriptor_name': 'HLA-DR Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060888', 'descriptor_name': 'Real-Time Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016176', 'descriptor_name': 'T-Lymphocyte Subsets', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26796651', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.85}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W412021590', 'https://openalex.org/W2783849630', 'https://openalex.org/W2470169071', 'https://openalex.org/W2463625467', 'https://openalex.org/W2388170261', 'https://openalex.org/W2370976773', 'https://openalex.org/W2164750677', 'https://openalex.org/W2040212555', 'https://openalex.org/W2008948681', 'https://openalex.org/W1676680578'], 'abstract_inverted_index': {'To': [0], 'analyze': [1], 'the': [2, 194], 'correlation': [3, 78, 123, 145, 153, 178], 'between': [4, 156], 'CD4(+)T': [5, 42, 46, 94, 105, 147, 180], 'cell': [6, 43, 47, 95, 106, 148, 181], 'count': [7, 96, 107, 182], 'and': [8, 28, 49, 75, 103, 162, 187], 'HLA-DR': [9, 34, 136, 188], 'or': [10, 35], 'CD38': [11, 36, 114, 157, 169, 186], 'expression': [12, 37, 51, 85, 115, 126, 137, 170], 'on': [13, 38, 52, 87, 116, 127, 138, 159, 171, 193], 'peripheral': [14, 39], 'CD8(+)T': [15, 40, 88, 117, 128, 139, 160, 172], 'cells': [16, 54, 89, 118, 129, 140, 161, 173], 'in': [17, 183, 198], 'treatment-naive': [18, 25, 184], 'Chinese': [19], 'HIV/AIDS': [20], 'patients.A': [21], 'total': [22], 'of': [23], '471': [24], 'HIV-infected': [26], 'patients': [27], '53': [29], 'healthy': [30], 'volunteers': [31], 'were': [32, 55, 80], 'enrolled.': [33], 'cells,': [41], 'count,': [44], 'naive': [45, 104], 'subsets': [48], 'CD28': [50, 125], 'T': [53], 'measured': [56], 'by': [57, 66], 'flow': [58], 'cytometry.': [59], 'Plasma': [60], 'HIV': [61, 164, 199], 'RNA': [62, 165], 'load': [63], 'was': [64, 90, 154], 'quantified': [65], 'real-time': [67], 'PCR': [68], '(COBAS': [69], 'TaqMan': [70], 'RT-PCR).': [71], 'Mann-Whitney': [72], 'U': [73], 'test': [74, 79], "Spearman's": [76], 'rank': [77], 'used': [81], 'for': [82], 'statistical': [83], 'analysis.CD38': [84], 'intensity': [86, 158], 'negatively': [91], 'correlated': [92], 'with': [93, 124, 146, 167, 179], '(r': [97, 108, 130], '=': [98, 109, 131], '-0.53,': [99], 'P': [100, 111, 133], '<': [101, 112, 134], '0.001)': [102], '-0.48,': [110], '0.001).': [113, 135], 'also': [119], 'displayed': [120], 'significantly': [121], 'negative': [122, 177], '-0.46,': [132], 'did': [141], 'not': [142], 'show': [143], 'significant': [144, 176], 'count.': [149], 'Only': [150], 'weak': [151], 'positive': [152], 'found': [155], 'plasma': [163], 'load.Compared': [166], 'HLA-DR,': [168], 'shows': [174], 'more': [175], 'patients.': [185], 'may': [189], 'play': [190], 'different': [191], 'roles': [192], 'persistent': [195], 'immune': [196], 'activation': [197], 'infection.': [200]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2470169071', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-24T12:13:25.339104', 'created_date': '2016-07-22'}