Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2469820590', 'doi': None, 'title': '[Overview of enzyme replacement therapy in mucopolysaccharidosis].', 'display_name': '[Overview of enzyme replacement therapy in mucopolysaccharidosis].', 'publication_year': 2007, 'publication_date': '2007-03-01', 'ids': {'openalex': 'https://openalex.org/W2469820590', 'mag': '2469820590', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17546776'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17546776', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5113892020', 'display_name': 'Alain Fouilhoux', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210123600', 'display_name': 'Hôpital Edouard Herriot', 'ror': 'https://ror.org/02qt1p572', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100596', 'https://openalex.org/I4210123600']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Alain Fouilhoux', 'raw_affiliation_strings': ['Centre de Référence des Maladies Héréditaires du Métabolisme, Hôpital Edouard-Herriot, Lyon (69), France.'], 'affiliations': [{'raw_affiliation_string': 'Centre de Référence des Maladies Héréditaires du Métabolisme, Hôpital Edouard-Herriot, Lyon (69), France.', 'institution_ids': ['https://openalex.org/I4210123600']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5053750627', 'display_name': 'Nathalie Guffon', 'orcid': 'https://orcid.org/0000-0002-3052-2366'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Nathalie Guffon', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2120, 'currency': 'USD', 'value_usd': 2120, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 63}, 'biblio': {'volume': '36 Spec No 1', 'issue': None, 'first_page': '1S96', 'last_page': '9'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10945', 'display_name': 'Lysosomal Storage Disorders Research', 'score': 0.9031, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10945', 'display_name': 'Lysosomal Storage Disorders Research', 'score': 0.9031, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/mucopolysaccharidosis', 'display_name': 'Mucopolysaccharidosis', 'score': 0.8134951}, {'id': 'https://openalex.org/keywords/mucopolysaccharidosis-type-ii', 'display_name': 'Mucopolysaccharidosis type II', 'score': 0.5311904}, {'id': 'https://openalex.org/keywords/mucopolysaccharidosis-i', 'display_name': 'Mucopolysaccharidosis I', 'score': 0.5189228}], 'concepts': [{'id': 'https://openalex.org/C2779969927', 'wikidata': 'https://www.wikidata.org/wiki/Q916766', 'display_name': 'Enzyme replacement therapy', 'level': 3, 'score': 0.9580858}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8919809}, {'id': 'https://openalex.org/C2779416428', 'wikidata': 'https://www.wikidata.org/wiki/Q1479681', 'display_name': 'Mucopolysaccharidosis', 'level': 2, 'score': 0.8134951}, {'id': 'https://openalex.org/C2910638406', 'wikidata': 'https://www.wikidata.org/wiki/Q1529983', 'display_name': 'Mucopolysaccharidosis type II', 'level': 4, 'score': 0.5311904}, {'id': 'https://openalex.org/C2910727661', 'wikidata': 'https://www.wikidata.org/wiki/Q25379699', 'display_name': 'Mucopolysaccharidosis I', 'level': 4, 'score': 0.5189228}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.44032168}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.36645246}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.32431084}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.26585758}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.10279751}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007066', 'descriptor_name': 'Iduronate Sulfatase', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D007068', 'descriptor_name': 'Iduronidase', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D009083', 'descriptor_name': 'Mucopolysaccharidoses', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D020051', 'descriptor_name': 'N-Acetylgalactosamine-4-Sulfatase', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D006025', 'descriptor_name': 'Glycosaminoglycans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006025', 'descriptor_name': 'Glycosaminoglycans', 'qualifier_ui': 'Q000652', 'qualifier_name': 'urine', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007066', 'descriptor_name': 'Iduronate Sulfatase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007068', 'descriptor_name': 'Iduronidase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009083', 'descriptor_name': 'Mucopolysaccharidoses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020051', 'descriptor_name': 'N-Acetylgalactosamine-4-Sulfatase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17546776', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.47, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4283362395', 'https://openalex.org/W4221019052', 'https://openalex.org/W3128228216', 'https://openalex.org/W3039642561', 'https://openalex.org/W2972937337', 'https://openalex.org/W2783930671', 'https://openalex.org/W2621730333', 'https://openalex.org/W2588822066', 'https://openalex.org/W1982375155', 'https://openalex.org/W1572142576'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2469820590', 'counts_by_year': [], 'updated_date': '2024-12-08T06:33:39.039832', 'created_date': '2016-07-22'}