Publication Information

{'id': 'https://openalex.org/W2469341065', 'doi': 'https://doi.org/10.1080/23744235.2016.1194528', 'title': 'Optimizing the virological success of tenofovir DF/FTC/rilpivirine in HIV-infected naive and virologically suppressed patients through strict clinical and virological selection*', 'display_name': 'Optimizing the virological success of tenofovir DF/FTC/rilpivirine in HIV-infected naive and virologically suppressed patients through strict clinical and virological selection*', 'publication_year': 2016, 'publication_date': '2016-07-08', 'ids': {'openalex': 'https://openalex.org/W2469341065', 'doi': 'https://doi.org/10.1080/23744235.2016.1194528', 'mag': '2469341065', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27389932'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/23744235.2016.1194528', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764422385', 'display_name': 'Infectious Diseases', 'issn_l': '2374-4235', 'issn': ['2374-4235', '2374-4243'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5014751777', 'display_name': 'C. Bernaud', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Camille Bernaud', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043205660', 'display_name': 'Lydie Khatchatourian', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Lydie Khatchatourian', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112145344', 'display_name': 'Audrey Rodallec', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Audrey Rodallec', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Virology Department, Nantes University Hospital, Nantes, France;'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Virology Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002570218', 'display_name': 'Nolwenn Hall', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Nolwenn Hall', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049548693', 'display_name': 'Philippe Van de Perre', 'orcid': 'https://orcid.org/0000-0002-3912-0427'}, 'institutions': [{'id': 'https://openalex.org/I4210107416', 'display_name': 'Roche (France)', 'ror': 'https://ror.org/01mqmer16', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I4210107416']}, {'id': 'https://openalex.org/I4210146871', 'display_name': 'Centre Hospitalier Départemental Vendée', 'ror': 'https://ror.org/05epqd940', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146871']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Philippe Perre', 'raw_affiliation_strings': ['CHD Vendée, Internal Medicine Department, La Roche sur Yon, France;'], 'affiliations': [{'raw_affiliation_string': 'CHD Vendée, Internal Medicine Department, La Roche sur Yon, France;', 'institution_ids': ['https://openalex.org/I4210107416', 'https://openalex.org/I4210146871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066117791', 'display_name': 'Marine Morrier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210146871', 'display_name': 'Centre Hospitalier Départemental Vendée', 'ror': 'https://ror.org/05epqd940', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146871']}, {'id': 'https://openalex.org/I4210107416', 'display_name': 'Roche (France)', 'ror': 'https://ror.org/01mqmer16', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I4210107416']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Marine Morrier', 'raw_affiliation_strings': ['CHD Vendée, Internal Medicine Department, La Roche sur Yon, France;'], 'affiliations': [{'raw_affiliation_string': 'CHD Vendée, Internal Medicine Department, La Roche sur Yon, France;', 'institution_ids': ['https://openalex.org/I4210146871', 'https://openalex.org/I4210107416']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003655695', 'display_name': 'Solène Pineau', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Solène Pineau', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'COREVIH Pays de la Loire, Nantes University Hospital, Nantes, France'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}, {'raw_affiliation_string': 'COREVIH Pays de la Loire, Nantes University Hospital, Nantes, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107073942', 'display_name': 'T Jovelin', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Thomas Jovelin', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'COREVIH Pays de la Loire, Nantes University Hospital, Nantes, France'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}, {'raw_affiliation_string': 'COREVIH Pays de la Loire, Nantes University Hospital, Nantes, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044116787', 'display_name': 'Elisabeth André‐Garnier', 'orcid': 'https://orcid.org/0000-0002-2139-5561'}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Elisabeth André-Garnier', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Virology Department, Nantes University Hospital, Nantes, France;'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Virology Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110215337', 'display_name': 'François Raffi', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'François Raffi', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5018167374', 'display_name': 'Clotilde Allavena', 'orcid': 'https://orcid.org/0000-0003-1010-1270'}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Clotilde Allavena', 'raw_affiliation_strings': ['CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;'], 'affiliations': [{'raw_affiliation_string': 'CHU Hôtel-Dieu, Infectious Diseases Department, Nantes University Hospital, Nantes, France;', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5018167374'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.718, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.552965, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': '48', 'issue': '10', 'first_page': '754', 'last_page': '759'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9963, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10082', 'display_name': 'HIV/AIDS Research and Interventions', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/rilpivirine', 'display_name': 'Rilpivirine', 'score': 0.9173726}, {'id': 'https://openalex.org/keywords/discontinuation', 'display_name': 'Discontinuation', 'score': 0.6886623}, {'id': 'https://openalex.org/keywords/resistance-mutation', 'display_name': 'Resistance mutation', 'score': 0.59525365}, {'id': 'https://openalex.org/keywords/dolutegravir', 'display_name': 'Dolutegravir', 'score': 0.55209047}, {'id': 'https://openalex.org/keywords/concordance', 'display_name': 'Concordance', 'score': 0.4251777}, {'id': 'https://openalex.org/keywords/regimen', 'display_name': 'Regimen', 'score': 0.4227085}], 'concepts': [{'id': 'https://openalex.org/C2778723075', 'wikidata': 'https://www.wikidata.org/wiki/Q421547', 'display_name': 'Rilpivirine', 'level': 5, 'score': 0.9173726}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8901275}, {'id': 'https://openalex.org/C2778715236', 'wikidata': 'https://www.wikidata.org/wiki/Q55622662', 'display_name': 'Discontinuation', 'level': 2, 'score': 0.6886623}, {'id': 'https://openalex.org/C182707283', 'wikidata': 'https://www.wikidata.org/wiki/Q7315622', 'display_name': 'Resistance mutation', 'level': 5, 'score': 0.59525365}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.56289864}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5545388}, {'id': 'https://openalex.org/C2779502633', 'wikidata': 'https://www.wikidata.org/wiki/Q937224', 'display_name': 'Dolutegravir', 'level': 5, 'score': 0.55209047}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.45405132}, {'id': 'https://openalex.org/C114851261', 'wikidata': 'https://www.wikidata.org/wiki/Q12147416', 'display_name': 'Drug resistance', 'level': 2, 'score': 0.44939357}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.4297147}, {'id': 'https://openalex.org/C160798450', 'wikidata': 'https://www.wikidata.org/wiki/Q4230870', 'display_name': 'Concordance', 'level': 2, 'score': 0.4251777}, {'id': 'https://openalex.org/C2781413609', 'wikidata': 'https://www.wikidata.org/wiki/Q7308373', 'display_name': 'Regimen', 'level': 2, 'score': 0.4227085}, {'id': 'https://openalex.org/C142462285', 'wikidata': 'https://www.wikidata.org/wiki/Q2528140', 'display_name': 'Viral load', 'level': 3, 'score': 0.4201702}, {'id': 'https://openalex.org/C31467283', 'wikidata': 'https://www.wikidata.org/wiki/Q912147', 'display_name': 'Genotyping', 'level': 4, 'score': 0.41751963}, {'id': 'https://openalex.org/C3013748606', 'wikidata': 'https://www.wikidata.org/wiki/Q15787', 'display_name': 'Human immunodeficiency virus (HIV)', 'level': 2, 'score': 0.32577646}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.2931357}, {'id': 'https://openalex.org/C2993143319', 'wikidata': 'https://www.wikidata.org/wiki/Q583050', 'display_name': 'Antiretroviral therapy', 'level': 4, 'score': 0.25682986}, {'id': 'https://openalex.org/C156719811', 'wikidata': 'https://www.wikidata.org/wiki/Q28774', 'display_name': 'Reverse transcriptase', 'level': 4, 'score': 0.16232193}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.123757124}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D004338', 'descriptor_name': 'Drug Combinations', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D064420', 'descriptor_name': 'Drug-Related Side Effects and Adverse Reactions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011446', 'descriptor_name': 'Prospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054328', 'descriptor_name': 'Proton Pump Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054328', 'descriptor_name': 'Proton Pump Inhibitors', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D054328', 'descriptor_name': 'Proton Pump Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D000072230', 'descriptor_name': 'Sustained Virologic Response', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013607', 'descriptor_name': 'Tablets', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013607', 'descriptor_name': 'Tablets', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D013607', 'descriptor_name': 'Tablets', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019562', 'descriptor_name': 'Viral Load', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/23744235.2016.1194528', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764422385', 'display_name': 'Infectious Diseases', 'issn_l': '2374-4235', 'issn': ['2374-4235', '2374-4243'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27389932', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.85, 'display_name': 'Life below water', 'id': 'https://metadata.un.org/sdg/14'}], 'grants': [{'funder': 'https://openalex.org/F4320308573', 'funder_display_name': 'Gilead Sciences', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 17, 'referenced_works': ['https://openalex.org/W1891905808', 'https://openalex.org/W1978364917', 'https://openalex.org/W1986351652', 'https://openalex.org/W1997578665', 'https://openalex.org/W2001278741', 'https://openalex.org/W2027613075', 'https://openalex.org/W2033711468', 'https://openalex.org/W2040200721', 'https://openalex.org/W2056557576', 'https://openalex.org/W2066710527', 'https://openalex.org/W2075836570', 'https://openalex.org/W2106467173', 'https://openalex.org/W2119711042', 'https://openalex.org/W2140562787', 'https://openalex.org/W2322601374', 'https://openalex.org/W2397692736', 'https://openalex.org/W4246000855'], 'related_works': ['https://openalex.org/W4280582041', 'https://openalex.org/W4247604720', 'https://openalex.org/W4210325848', 'https://openalex.org/W3207788568', 'https://openalex.org/W3143772066', 'https://openalex.org/W2969804444', 'https://openalex.org/W2961032584', 'https://openalex.org/W2910368971', 'https://openalex.org/W2900399017', 'https://openalex.org/W2810063204'], 'abstract_inverted_index': {'Background:': [0], 'Tenofovir': [1], 'DF/FTC/rilpivirine': [2], '(TDF/FTC/RPV)': [3], 'is': [4, 49], 'a': [5, 37, 50, 90, 156], 'single': [6], 'tablet': [7], 'regimen': [8], 'considered': [9, 75, 113], 'as': [10, 17, 19], 'safe': [11], 'and': [12, 25, 44, 190, 233], 'efficacious': [13], 'in': [14, 36, 149, 165, 179, 186, 193], 'HIV': [15, 64], 'population': [16], 'long': [18], 'food': [20], 'requirements,': [21], 'concomitant': [22], 'PPI': [23, 141], 'administration,': [24], 'compromised': [26], 'antiviral': [27], 'activity': [28], 'have': [29], 'been': [30], 'carefully': [31], 'reviewed.': [32], 'We': [33], 'evaluated': [34], 'TDF/FTC/RPV': [35, 85, 111, 177, 214], 'real-life': [38, 205], 'setting': [39], 'with': [40, 63], 'focus': [41], 'on': [42, 134], 'clinical': [43, 232], 'virological': [45, 131, 162, 234, 242], 'outcomes.Methods:': [46], 'OCEAN': [47], 'II': [48], 'prospective,': [51], 'two-centre': [52], 'observational': [53], 'study.': [54], 'From': [55], 'September': [56], '2012': [57], 'to': [58, 70, 84, 96, 121, 183, 227], 'December': [59], '2013,': [60], 'antiretroviral-naive': [61], 'patients': [62, 123, 147, 167, 188, 195], 'RNA': [65, 106], '<100,000': [66], 'copies/mL': [67], 'or': [68, 140], 'wishing': [69], 'switch': [71], 'for': [72, 76, 114], 'simplification': [73], 'were': [74], 'TDF/FTC/RPV.': [77, 154], 'A': [78, 143], 'systematic': [79], 'review': [80], 'of': [81, 127, 129, 145, 159, 172, 176, 210, 220, 223, 241], 'potential': [82], 'obstacles': [83], 'administration': [86], 'was': [87, 109, 112, 118, 225], 'undertaken': [88], 'during': [89], 'multidisciplinary': [91], 'meeting,': [92], 'including': [93], 'DNA': [94], 'genotyping': [95], 'detect': [97], 'archived': [98], 'RPV': [99], 'and/or': [100], 'NRTI-associated': [101], 'resistance': [102, 107, 173], 'mutations': [103], 'if': [104], 'historical': [105], 'testing': [108], 'lacking.Results:': [110], '480': [115], 'patients,': [116, 181, 213], 'however': [117], 'not': [119], 'offered': [120], '194': [122], '(40%),': [124], 'mainly': [125], 'because': [126, 222], 'risk': [128], 'insufficient': [130], 'efficacy,': [132], 'issues': [133], 'adherence,': [135], 'patient': [136], 'refusal,': [137], 'meal': [138], 'constraint,': [139], 'therapy.': [142], 'total': [144], '286': [146], '(269': [148], 'maintenance;': [150], '17': [151], 'ART-naive)': [152], 'received': [153], 'After': [155], 'median': [157], 'follow-up': [158], '30': [160], 'months,': [161], 'failure': [163], 'occurred': [164, 178], 'five': [166], '(1.7%)': [168], 'without': [169], 'the': [170, 238], 'emergence': [171], 'mutations.': [174], 'Discontinuation': [175, 219], '98': [180], 'due': [182, 226], 'adverse': [184, 200, 229], 'events': [185, 201], '43': [187], '(44%)': [189], 'non-safety': [191], 'reasons': [192], '55': [194], '(56%).': [196], 'No': [197], 'grade': [198], 'three-fourth': [199], 'occurred.Conclusion:': [202], 'In': [203], 'this': [204], 'experience,': [206], 'cohort': [207], 'consisting': [208], 'primarily': [209], 'virologically': [211], 'suppressed': [212], 'usually': [215], 'maintained': [216], 'virologic': [217], 'suppression.': [218], 'therapy': [221], 'intolerability': [224], 'mild': [228], 'events.': [230], 'Strict': [231], 'screening': [235], 'probably': [236], 'explained': [237], 'low': [239], 'rate': [240], 'failure.': [243]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2469341065', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}], 'updated_date': '2024-12-09T21:12:22.289432', 'created_date': '2016-07-22'}