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[11], 'lymphatic': [12], 'route.': [13], 'During': [14], 'the': [15, 21, 25, 31, 41, 55, 89, 200, 218], 'invasion,': [16], 'tumor': [17, 141, 207], 'cells': [18, 208], 'break': [19], 'basement': [22], 'membrane,': [23], 'penetrate': [24], 'connective': [26, 42], 'tissue': [27, 43], 'to': [28, 39, 222], 'interact': [29], 'with': [30], 'extracellular': [32], 'matrix': [33], '(ECM).': [34], 'An': [35], 'attempt': [36], 'was': [37, 103], 'made': [38], 'evaluate': [40], 'changes': [44, 94], 'in': [45, 53, 125, 143, 155, 160, 174, 186, 217], 'different': [46, 144], 'grades': [47, 145], 'of': [48, 58, 65, 91, 100, 146, 192, 199, 220], 'OSCCs': [49], 'and': [50, 61, 81, 106, 128, 158, 162, 176, 181, 203], 'their': [51, 224], 'influence': [52], 'predicting': [54], 'biological': [56], 'behavior': [57], 'these': [59], 'tumors.<br><b>Materials': [60], 'Methods:</b>': [62], 'A': [63], 'total': [64], '30': [66], 'histologically': [67], 'proven': [68], 'cases': [69, 180], 'comprising': [70], '5': [71, 82], 'normal': [72], 'mucosa,': [73], '10': [74, 77], 'well-differentiated': [75, 156], "OSCC's,": [76, 80, 130], 'moderately': [78, 161, 177], 'differentiated': [79, 84, 164, 178, 188], 'poorly': [83, 163, 187], "OSCC's": [85], 'were': [86], 'examined': [87], 'for': [88, 137, 153], 'presence': [90], 'any': [92], 'ECM': [93, 221], 'by': [95], 'using': [96], 'special': [97], 'stains.': [98], 'Interpretation': [99], 'staining': [101, 136, 152, 197], 'intensity': [102], 'carried': [104], 'out': [105], 'statistically': [107], 'analyzed.<br><b>Results:</b>': [108], 'Van': [109], 'Gieson': [110], 'stain': [111, 149, 168], 'showed': [112, 134, 150, 169], 'abundant': [113], 'thick': [114], 'collagen': [115, 118, 123, 172, 184], 'fibers,': [116, 119], 'dispersed': [117, 122], 'thin': [120], 'few': [121], 'fibers': [124, 139, 173, 185], 'well-,': [126], 'moderately-': [127], 'poorly-differentiated': [129], 'respectively.': [131], "Verhoeff's": [132], 'Van-Gieson': [133], 'negative': [135, 159], 'elastic': [138], 'around': [140], 'islands': [142], 'OSCCs.': [147], 'PAS': [148], 'moderate': [151], 'glycoprotein': [154], 'OSCC': [157, 179], 'cases.': [165], 'Picrosirius': [166], 'red': [167], 'Type': [170, 182], '1': [171], 'well': [175], '3': [183], 'cases.<br><b>Conclusion:</b>': [189], 'The': [190], 'observations': [191], 'this': [193], 'study': [194], 'revealed': [195], 'altered': [196], 'reactions': [198], 'collagenous': [201], 'stroma': [202], 'glycoproteins': [204], 'suggesting': [205], 'that': [206, 213], 'may': [209], 'release': [210], 'certain': [211], 'enzymes': [212], 'play': [214], 'a': [215], 'role': [216], 'manipulation': [219], 'enhance': [223], 'own': [225], 'survival.': [226]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2468482888', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 3}], 'updated_date': '2024-12-18T14:48:18.204846', 'created_date': 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