Publication Information

{'id': 'https://openalex.org/W2463575338', 'doi': 'https://doi.org/10.1016/s1016-8478(23)13167-0', 'title': 'Endoplasmic Reticulum Ca2+ Store: Regulation of Ca2+ Release and Reuptake by Intracellular and Extracellular Ca2+ in Pancreatic Acinar Cells', 'display_name': 'Endoplasmic Reticulum Ca2+ Store: Regulation of Ca2+ Release and Reuptake by Intracellular and Extracellular Ca2+ in Pancreatic Acinar Cells', 'publication_year': 2005, 'publication_date': '2005-04-01', 'ids': {'openalex': 'https://openalex.org/W2463575338', 'doi': 'https://doi.org/10.1016/s1016-8478(23)13167-0', 'mag': '2463575338', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15879713'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/s1016-8478(23)13167-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171170158', 'display_name': 'Molecules and Cells', 'issn_l': '1016-8478', 'issn': ['1016-8478', '0219-1032'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://doi.org/10.1016/s1016-8478(23)13167-0', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5042358456', 'display_name': 'Yun Kyung Kang', 'orcid': 'https://orcid.org/0000-0002-2075-4665'}, 'institutions': [{'id': 'https://openalex.org/I4210160997', 'display_name': 'Inje University Seoul Paik Hospital', 'ror': 'https://ror.org/05we5gj17', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210160997']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Yun Kyung Kang', 'raw_affiliation_strings': ['Department of Pathology, Inje University Seoul Paik Hospital, Seoul 100-032, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Inje University Seoul Paik Hospital, Seoul 100-032, Korea', 'institution_ids': ['https://openalex.org/I4210160997']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5011001216', 'display_name': 'Myoung Kyu Park', 'orcid': 'https://orcid.org/0000-0001-8111-6096'}, 'institutions': [{'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}, {'id': 'https://openalex.org/I2250650973', 'display_name': 'Samsung (South Korea)', 'ror': 'https://ror.org/04w3jy968', 'country_code': 'KR', 'type': 'company', 'lineage': ['https://openalex.org/I2250650973']}], 'countries': ['KR'], 'is_corresponding': True, 'raw_author_name': 'Myoung Kyu Park', 'raw_affiliation_strings': ['Department of Physiology and Center for Molecular Medicine, Sungkyunkwan University School of Medicine and Samsung Biomedical Research Institute, Suwon 440-746, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology and Center for Molecular Medicine, Sungkyunkwan University School of Medicine and Samsung Biomedical Research Institute, Suwon 440-746, Korea', 'institution_ids': ['https://openalex.org/I848706', 'https://openalex.org/I2250650973']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5011001216'], 'corresponding_institution_ids': ['https://openalex.org/I848706', 'https://openalex.org/I2250650973'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.62, 'has_fulltext': False, 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.550195, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': '19', 'issue': '2', 'first_page': '268', 'last_page': '278'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9963, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13415', 'display_name': 'Calcium signaling and nucleotide metabolism', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bapta', 'display_name': 'BAPTA', 'score': 0.5236285}, {'id': 'https://openalex.org/keywords/fura-2', 'display_name': 'Fura-2', 'score': 0.51470095}, {'id': 'https://openalex.org/keywords/orai1', 'display_name': 'Orai1', 'score': 0.4264072}], 'concepts': [{'id': 'https://openalex.org/C28406088', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Extracellular', 'level': 2, 'score': 0.8708989}, {'id': 'https://openalex.org/C98539663', 'wikidata': 'https://www.wikidata.org/wiki/Q220599', 'display_name': 'Cytosol', 'level': 3, 'score': 0.7592882}, {'id': 'https://openalex.org/C158617107', 'wikidata': 'https://www.wikidata.org/wiki/Q79927', 'display_name': 'Endoplasmic reticulum', 'level': 2, 'score': 0.6559916}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.6288589}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.5328634}, {'id': 'https://openalex.org/C2780019300', 'wikidata': 'https://www.wikidata.org/wiki/Q4834614', 'display_name': 'BAPTA', 'level': 3, 'score': 0.5236285}, {'id': 'https://openalex.org/C2778470358', 'wikidata': 'https://www.wikidata.org/wiki/Q908761', 'display_name': 'Fura-2', 'level': 4, 'score': 0.51470095}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5111638}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4316172}, {'id': 'https://openalex.org/C2776610495', 'wikidata': 'https://www.wikidata.org/wiki/Q18047835', 'display_name': 'ORAI1', 'level': 4, 'score': 0.4264072}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.28583002}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.27208686}, {'id': 'https://openalex.org/C162740809', 'wikidata': 'https://www.wikidata.org/wiki/Q15334560', 'display_name': 'STIM1', 'level': 3, 'score': 0.13505024}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004721', 'descriptor_name': 'Endoplasmic Reticulum', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D046790', 'descriptor_name': 'Pancreas, Exocrine', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D000109', 'descriptor_name': 'Acetylcholine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020013', 'descriptor_name': 'Calcium Signaling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002614', 'descriptor_name': 'Chelating Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D004533', 'descriptor_name': 'Egtazic Acid', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': False}, {'descriptor_ui': 'D007424', 'descriptor_name': 'Intracellular Fluid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017136', 'descriptor_name': 'Ion Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008564', 'descriptor_name': 'Membrane Potentials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014665', 'descriptor_name': 'Vasodilator Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/s1016-8478(23)13167-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171170158', 'display_name': 'Molecules and Cells', 'issn_l': '1016-8478', 'issn': ['1016-8478', '0219-1032'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15879713', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/s1016-8478(23)13167-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171170158', 'display_name': 'Molecules and Cells', 'issn_l': '1016-8478', 'issn': ['1016-8478', '0219-1032'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/6', 'score': 0.63, 'display_name': 'Clean water and sanitation'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 38, 'referenced_works': ['https://openalex.org/W1551064372', 'https://openalex.org/W1598963691', 'https://openalex.org/W1966051958', 'https://openalex.org/W1968818999', 'https://openalex.org/W1980997572', 'https://openalex.org/W1982806922', 'https://openalex.org/W1993088121', 'https://openalex.org/W1997778815', 'https://openalex.org/W2004540956', 'https://openalex.org/W2009225669', 'https://openalex.org/W2009441758', 'https://openalex.org/W2009667219', 'https://openalex.org/W2014478550', 'https://openalex.org/W2015868082', 'https://openalex.org/W2033739116', 'https://openalex.org/W2041690080', 'https://openalex.org/W2052260043', 'https://openalex.org/W2052831035', 'https://openalex.org/W2065771385', 'https://openalex.org/W2070253406', 'https://openalex.org/W2070328077', 'https://openalex.org/W2082588556', 'https://openalex.org/W2093364468', 'https://openalex.org/W2096207669', 'https://openalex.org/W2106519810', 'https://openalex.org/W2108578589', 'https://openalex.org/W2119825883', 'https://openalex.org/W2128270335', 'https://openalex.org/W2132210046', 'https://openalex.org/W2141255220', 'https://openalex.org/W2143520831', 'https://openalex.org/W2144190351', 'https://openalex.org/W2146319595', 'https://openalex.org/W2152772170', 'https://openalex.org/W2164891652', 'https://openalex.org/W2168143869', 'https://openalex.org/W2751467153', 'https://openalex.org/W4244770895'], 'related_works': ['https://openalex.org/W2889423659', 'https://openalex.org/W2585793758', 'https://openalex.org/W2138533476', 'https://openalex.org/W2125150174', 'https://openalex.org/W2044849142', 'https://openalex.org/W2039699920', 'https://openalex.org/W2038951793', 'https://openalex.org/W2024494936', 'https://openalex.org/W2018994202', 'https://openalex.org/W2006951303'], 'abstract_inverted_index': {'We': [0], 'investigated': [1], 'the': [2, 21, 25, 28, 36, 48, 53, 61, 67, 82, 145, 187, 196, 218], 'effect': [3], 'of': [4, 27, 52, 57, 69, 103, 148, 178, 189, 212], 'cytosolic': [5], 'and': [6, 23, 33, 98, 116, 192, 224], 'extracellular': [7, 104, 134, 201, 213], 'Ca2+': [8, 10, 18, 45, 58, 73, 80, 105, 143, 153, 170, 182, 190], 'on': [9], 'signals': [11], 'in': [12, 20, 24, 35, 121, 195], 'pancreatic': [13, 127], 'acinar': [14, 128], 'cells': [15, 129, 149], 'by': [16, 77, 175, 186, 210, 217, 221], 'measuring': [17], 'concentration': [19], 'cytosol([Ca2+]c)': [22], 'lumen': [26], 'ER([Ca2+]Lu).': [29], 'To': [30], 'control': [31], 'buffers': [32], 'dye': [34], 'cytosol,': [37], 'a': [38, 91], 'patch-clamp': [39], 'microelectrode': [40], 'was': [41, 63, 75], 'employed.': [42], 'Acetylcholine': [43], 'released': [44], 'mainly': [46, 194], 'from': [47, 60, 109, 144], 'basolateral': [49], 'ER-rich': [50], 'part': [51], 'cell.': [54], 'The': [55], 'rate': [56, 188], 'release': [59, 171], 'ER': [62, 72, 169, 181, 219], 'highly': [64], 'sensitive': [65], 'to': [66, 81, 106, 132, 138, 150, 206], 'buffering': [68], '[Ca2+]c': [70, 85, 114, 119, 203, 223], 'whereas': [71], 'refilling': [74, 183], 'enhanced': [76], 'supplying': [78], 'free': [79], 'cytosol': [83], 'with': [84, 90], 'clamped': [86], 'at': [87], 'resting': [88, 113], 'levels': [89], 'patch': [92], 'pipette': [93], 'containing': [94], '10': [95, 107, 151], 'mM': [96, 100, 108, 111, 152], 'BAPTA': [97], '2': [99], 'Ca2+.': [101], 'Elevation': [102], '1': [110], 'raised': [112, 160], 'slightly': [115], 'often': [117], 'generated': [118], 'oscillations': [120, 204], 'single': [122], 'or': [123], 'clustered': [124], 'cells.': [125], 'Although': [126], 'are': [130], 'reported': [131], 'have': [133], 'Ca2+-sensing': [135, 214], 'receptors': [136, 215], 'linked': [137], 'phospholipase': [139], 'C': [140], 'that': [141, 167], 'mobilize': [142], 'ER,': [146], 'exposure': [147], 'did': [154], 'not': [155, 209], 'decrease': [156], '[Ca2+]Lu': [157], 'but': [158, 216], 'rather': [159], 'it.': [161], 'From': [162], 'these': [163], 'findings': [164], 'we': [165], 'conclude': [166], '1)': [168], 'is': [172, 184], 'strictly': [173], 'regulated': [174], 'feedback': [176], 'inhibition': [177], '[Ca2+]c,': [179], '2)': [180], 'determined': [185], 'influx': [191], 'occurs': [193], 'tiny': [197], 'subplasmalemmal': [198], 'spaces,': [199], '3)': [200], 'Ca2+-induced': [202], 'appear': [205], 'be': [207], 'triggered': [208], 'activation': [211], 'sensitised': [220], 'elevated': [222], '[Ca2+]Lu.': [225]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2463575338', 'counts_by_year': [{'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-09T10:36:46.674907', 'created_date': '2016-07-22'}