Title: Interference of glucosamine and other aminosugars on blast transformation.
Abstract: The effect of exogenous glucosamine and other aminosugars on the incorporation of 3H-leucine 3H-uridine and 3H-thymidine into mitogen induced lymphocytes was studied. D-glucosamine D-galactosamine and D-mannosamine inhibit the incorporation of these precursors into protein. RNA and DNA of blast cells. Glucose and pyruvate did not reverse this inhibition. Glucosamine - 6P, acetylglucosamine and acetylglucosamine and have shown a considerably lower inhibition in the uptake of these labeled precursors.
Publication Year: 1981
Publication Date: 1981-06-15
Language: en
Type: article
Indexed In: ['pubmed']
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