Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2462655815', 'doi': 'https://doi.org/10.1042/bst0080190', 'title': 'Inhibition by tunicamycin of glycoprotein synthesis and secretion in isolated rat hepatocytes', 'display_name': 'Inhibition by tunicamycin of glycoprotein synthesis and secretion in isolated rat hepatocytes', 'publication_year': 1980, 'publication_date': '1980-04-01', 'ids': {'openalex': 'https://openalex.org/W2462655815', 'doi': 'https://doi.org/10.1042/bst0080190', 'mag': '2462655815', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7371964'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bst0080190', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S137670264', 'display_name': 'Biochemical Society Transactions', 'issn_l': '0300-5127', 'issn': ['0300-5127', '1470-8752'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5013426761', 'display_name': 'Tony Howe', 'orcid': None}, 'institutions': [], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'TONY HOWE', 'raw_affiliation_strings': ['Department of Biochemistry, University College, P.O. Box 78, Cardiff CF1 1XL, Wales, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University College, P.O. Box 78, Cardiff CF1 1XL, Wales, U.K.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037872309', 'display_name': 'JOHN R. VOISEY', 'orcid': None}, 'institutions': [], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'JOHN R. VOISEY', 'raw_affiliation_strings': ['Department of Biochemistry, University College, P.O. Box 78, Cardiff CF1 1XL, Wales, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University College, P.O. Box 78, Cardiff CF1 1XL, Wales, U.K.', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5008448511', 'display_name': 'P. J. Winterburn', 'orcid': None}, 'institutions': [], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'PETER J. WINTERBURN', 'raw_affiliation_strings': ['Department of Biochemistry, University College, P.O. Box 78, Cardiff CF1 1XL, Wales, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University College, P.O. Box 78, Cardiff CF1 1XL, Wales, U.K.', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.168, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.604058, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 71, 'max': 74}, 'biblio': {'volume': '8', 'issue': '2', 'first_page': '190', 'last_page': '191'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10835', 'display_name': 'Chemical Glycobiology and Therapeutic Applications', 'score': 0.9935, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10835', 'display_name': 'Chemical Glycobiology and Therapeutic Applications', 'score': 0.9935, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'Ribosome Structure and Translation Mechanisms', 'score': 0.9922, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10252', 'display_name': 'Natural Products as Sources of New Drugs', 'score': 0.9907, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/icon', 'display_name': 'Icon', 'score': 0.705639}, {'id': 'https://openalex.org/keywords/glycoprotein-synthesis', 'display_name': 'Glycoprotein Synthesis', 'score': 0.543433}, {'id': 'https://openalex.org/keywords/tunicamycin', 'display_name': 'Tunicamycin', 'score': 0.43310928}], 'concepts': [{'id': 'https://openalex.org/C2778805511', 'wikidata': 'https://www.wikidata.org/wiki/Q1713', 'display_name': 'Citation', 'level': 2, 'score': 0.73075247}, {'id': 'https://openalex.org/C2778447006', 'wikidata': 'https://www.wikidata.org/wiki/Q1156474', 'display_name': 'Icon', 'level': 2, 'score': 0.705639}, {'id': 'https://openalex.org/C2777575526', 'wikidata': 'https://www.wikidata.org/wiki/Q3542091', 'display_name': 'Tunicamycin', 'level': 4, 'score': 0.43310928}, {'id': 'https://openalex.org/C49039625', 'wikidata': 'https://www.wikidata.org/wiki/Q84230', 'display_name': 'Secretion', 'level': 2, 'score': 0.4312052}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.38163877}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.33328366}, {'id': 'https://openalex.org/C23123220', 'wikidata': 'https://www.wikidata.org/wiki/Q816826', 'display_name': 'Information retrieval', 'level': 1, 'score': 0.33253115}, {'id': 'https://openalex.org/C142362112', 'wikidata': 'https://www.wikidata.org/wiki/Q735', 'display_name': 'Art', 'level': 0, 'score': 0.33041364}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.3065725}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.25042808}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08635625}, {'id': 'https://openalex.org/C139447449', 'wikidata': 'https://www.wikidata.org/wiki/Q14633900', 'display_name': 'Unfolded protein response', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C199360897', 'wikidata': 'https://www.wikidata.org/wiki/Q9143', 'display_name': 'Programming language', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005944', 'descriptor_name': 'Glucosamine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014415', 'descriptor_name': 'Tunicamycin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005944', 'descriptor_name': 'Glucosamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014415', 'descriptor_name': 'Tunicamycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bst0080190', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S137670264', 'display_name': 'Biochemical Society Transactions', 'issn_l': '0300-5127', 'issn': ['0300-5127', '1470-8752'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7371964', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4360922125', 'https://openalex.org/W3175319091', 'https://openalex.org/W2172668814', 'https://openalex.org/W2075740646', 'https://openalex.org/W2074118786', 'https://openalex.org/W2066874449', 'https://openalex.org/W2056060060', 'https://openalex.org/W2054517996', 'https://openalex.org/W2038641205', 'https://openalex.org/W1607532301'], 'abstract_inverted_index': {'Conference': [0], 'Article|': [1], 'April': [2, 168], '01': [3], '1980': [4, 221], 'Inhibition': [5, 152], 'by': [6, 38, 70, 102, 153], 'tunicamycin': [7, 154], 'of': [8, 22, 54, 86, 155], 'glycoprotein': [9, 156], 'synthesis': [10, 157], 'and': [11, 158], 'secretion': [12, 159], 'in': [13, 160], 'isolated': [14, 161], 'rat': [15, 162], 'hepatocytes': [16], 'TONY': [17, 19, 144], 'HOWE;': [18], 'HOWE': [20], '1Department': [21, 53, 85], 'Biochemistry,': [23, 55, 87], 'University': [24, 56, 88], 'College,': [25, 57, 89], 'P.O.': [26, 58, 90], 'Box': [27, 59, 91], '78,': [28, 60, 92], 'Cardiff': [29, 61, 93], 'CF1': [30, 62, 94], '1XL,': [31, 63, 95], 'Wales,': [32, 64, 96], 'U.K.': [33, 65, 97], 'Search': [34, 66, 98, 191, 198, 209, 211], 'for': [35, 67, 99], 'other': [36, 68, 100], 'works': [37, 69, 101], 'this': [39, 71, 103, 238], 'author': [40, 72, 104], 'on:': [41, 73, 105], 'This': [42, 74, 106, 212], 'Site': [43, 75, 107], 'PubMed': [44, 76, 108], 'Google': [45, 77, 109], 'Scholar': [46, 78, 110], 'JOHN': [47, 50, 146], 'R.': [48, 51, 147], 'VOISEY;': [49], 'VOISEY': [52], 'PETER': [79, 82, 149], 'J.': [80, 83, 150], 'WINTERBURN': [81, 84], 'Biochem': [111, 164], 'Soc': [112, 165], 'Trans': [113, 166], '(1980)': [114], '8': [115, 170], '(2):': [116, 171], '190–191.': [117, 172], 'https://doi.org/10.1042/bst0080190': [118, 174], 'Views': [119, 121], 'Icon': [120, 134, 139], 'Article': [122, 224], 'contents': [123], 'Figures': [124], '&': [125], 'tables': [126], 'Video': [127], 'Audio': [128], 'Supplementary': [129], 'Data': [130], 'Peer': [131], 'Review': [132], 'Share': [133, 135], 'Twitter': [136], 'LinkedIn': [137], 'Cite': [138, 140], 'Get': [141], 'Permissions': [142], 'Citation': [143], 'HOWE,': [145], 'VOISEY,': [148], 'WINTERBURN;': [151], 'hepatocytes.': [163], '1': [167], '1980;': [169], 'doi:': [173], 'Download': [175], 'citation': [176], 'file:': [177], 'Ris': [178], '(Zotero)': [179], 'Reference': [180], 'Manager': [181], 'EasyBib': [182], 'Bookends': [183], 'Mendeley': [184], 'Papers': [185], 'EndNote': [186], 'RefWorks': [187], 'BibTex': [188], 'toolbar': [189], 'search': [190, 195, 196, 202], 'Dropdown': [192], 'Menu': [193], 'nav': [194], 'input': [197, 199], 'auto': [200], 'suggest': [201], 'filter': [203], 'All': [204], 'ContentAll': [205], 'JournalsBiochemical': [206], 'Society': [207], 'Transactions': [208], 'Advanced': [210], 'content': [213], 'is': [214], 'only': [215], 'available': [216], 'as': [217], 'a': [218], 'PDF.': [219], '©': [220], 'Biochemical': [222], 'Society1980': [223], 'PDF': [225], 'first': [226], 'page': [227], 'preview': [228], 'Close': [229], 'Modal': [230], 'You': [231], 'do': [232], 'not': [233], 'currently': [234], 'have': [235], 'access': [236], 'to': [237], 'content.': [239]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2462655815', 'counts_by_year': [], 'updated_date': '2024-09-18T02:51:26.889769', 'created_date': '2016-07-22'}