5-aza-2′-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells

Name: Work Video:
Duration: 3 min 30 s
Maximilian Stich; Lennard Ganss; Jens Puschhof; Elena‐Sophie Prigge; Miriam Reuschenbach; Ana Guiterrez; Svetlana Vinokurova; Magnus von Knebel Doeberitz
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'including': [134], 'p53': [135], 'p21': [137], 'reducing': [138], 'proliferation': [140], 'rates': [141], 'colony': [143], 'formation': [144], 'abilities': [145], 'treated': [148], 'Moreover,': [151], 'DAC': [152, 175], 'led': [154], 'to': [155, 189], 'enhanced': [156], 'suppressive': [161], 'miRNA-375': [162], 'targets': [164], 'degrades': [166], 'transcripts.': [170], 'suggest': [173], 'HPV-associated': [178], 'respective': [181], 'precursor': [182], 'lesions': [183], 'constitute': [185], 'targeted': [187], 'approach': [188], 'subvert': [190], 'HPV': [191], 'oncogene': [192], 'functions': [193], 'deserves': [195], 'testing': [196], 'clinical': [198], 'trials.': [199]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2460408478', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 5}], 'updated_date': '2024-12-13T09:55:35.334526', 'created_date': '2016-07-22'}
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