Publication Information

{'id': 'https://openalex.org/W2442109640', 'doi': 'https://doi.org/10.18632/oncotarget.12310', 'title': 'c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer', 'display_name': 'c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer', 'publication_year': 2016, 'publication_date': '2016-09-28', 'ids': {'openalex': 'https://openalex.org/W2442109640', 'doi': 'https://doi.org/10.18632/oncotarget.12310', 'mag': '2442109640', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27689328', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5342763'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.12310', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=12310&path%5B%5D=49554', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=12310&path%5B%5D=49554', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5033804791', 'display_name': 'Peterson Kariuki Maina', 'orcid': 'https://orcid.org/0000-0002-5909-190X'}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Peterson Kariuki Maina', 'raw_affiliation_strings': ['Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015571143', 'display_name': 'Peng Shao', 'orcid': 'https://orcid.org/0000-0002-8453-6480'}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Peng Shao', 'raw_affiliation_strings': ['Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100453212', 'display_name': 'Qi Liu', 'orcid': 'https://orcid.org/0000-0002-5936-7005'}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Qi Liu', 'raw_affiliation_strings': ['Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034110828', 'display_name': 'Ladan Fazli', 'orcid': 'https://orcid.org/0000-0001-6488-4245'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Ladan Fazli', 'raw_affiliation_strings': ['Vancouver Prostate Center, Department of Urology Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada'], 'affiliations': [{'raw_affiliation_string': 'Vancouver Prostate Center, Department of Urology Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada', 'institution_ids': ['https://openalex.org/I141945490']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029141568', 'display_name': 'Scott R. Tyler', 'orcid': 'https://orcid.org/0000-0002-7683-6686'}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Scott Tyler', 'raw_affiliation_strings': ['Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019385304', 'display_name': 'Moman Nasir', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Moman Nasir', 'raw_affiliation_strings': ['Department of Health and Human Physiology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA 52242, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Health and Human Physiology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA 52242, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073827712', 'display_name': 'Xuesen Dong', 'orcid': 'https://orcid.org/0000-0002-3115-3371'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Xuesen Dong', 'raw_affiliation_strings': ['Vancouver Prostate Center, Department of Urology Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada'], 'affiliations': [{'raw_affiliation_string': 'Vancouver Prostate Center, Department of Urology Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada', 'institution_ids': ['https://openalex.org/I141945490']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5022968189', 'display_name': 'Hank H. Qi', 'orcid': 'https://orcid.org/0000-0002-3401-4940'}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Hank Heng Qi', 'raw_affiliation_strings': ['Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5022968189'], 'corresponding_institution_ids': ['https://openalex.org/I126307644'], 'apc_list': None, 'apc_paid': None, 'fwci': 3.764, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 51, 'citation_normalized_percentile': {'value': 0.917078, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '7', 'issue': '46', 'first_page': '75585', 'last_page': '75602'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10124', 'display_name': 'Prostate Cancer Diagnosis and Treatment', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tramp', 'display_name': 'Tramp', 'score': 0.8899088}, {'id': 'https://openalex.org/keywords/enzalutamide', 'display_name': 'Enzalutamide', 'score': 0.7293852}, {'id': 'https://openalex.org/keywords/demethylase', 'display_name': 'Demethylase', 'score': 0.65625906}, {'id': 'https://openalex.org/keywords/neuroendocrine-differentiation', 'display_name': 'Neuroendocrine differentiation', 'score': 0.4546613}], 'concepts': [{'id': 'https://openalex.org/C2780940892', 'wikidata': 'https://www.wikidata.org/wiki/Q1965933', 'display_name': 'Tramp', 'level': 4, 'score': 0.8899088}, {'id': 'https://openalex.org/C2779723316', 'wikidata': 'https://www.wikidata.org/wiki/Q6459234', 'display_name': 'LNCaP', 'level': 4, 'score': 0.8886385}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.76133144}, {'id': 'https://openalex.org/C2776551883', 'wikidata': 'https://www.wikidata.org/wiki/Q1996756', 'display_name': 'Enzalutamide', 'level': 5, 'score': 0.7293852}, {'id': 'https://openalex.org/C2781364455', 'wikidata': 'https://www.wikidata.org/wiki/Q2531584', 'display_name': 'Demethylase', 'level': 4, 'score': 0.65625906}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.6332253}, {'id': 'https://openalex.org/C173396325', 'wikidata': 'https://www.wikidata.org/wiki/Q1501275', 'display_name': 'Gene knockdown', 'level': 3, 'score': 0.5161763}, {'id': 'https://openalex.org/C61367390', 'wikidata': 'https://www.wikidata.org/wiki/Q416601', 'display_name': 'Androgen receptor', 'level': 4, 'score': 0.5107889}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.4889237}, {'id': 'https://openalex.org/C2780341458', 'wikidata': 'https://www.wikidata.org/wiki/Q18391873', 'display_name': 'Neuroendocrine differentiation', 'level': 4, 'score': 0.4546613}, {'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.41635975}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39357418}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.36507088}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.3276322}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.2438274}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.20071611}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D056466', 'descriptor_name': 'Histone Demethylases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D018358', 'descriptor_name': 'Neuroendocrine Tumors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D020413', 'descriptor_name': "3' Untranslated Regions", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D059447', 'descriptor_name': 'Cell Cycle Checkpoints', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D044127', 'descriptor_name': 'Epigenesis, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D016259', 'descriptor_name': 'Genes, myc', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D056484', 'descriptor_name': 'Jumonji Domain-Containing Histone Demethylases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060787', 'descriptor_name': 'Neoplasm Grading', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011944', 'descriptor_name': 'Receptors, Androgen', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D059467', 'descriptor_name': 'Transcriptome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.12310', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=12310&path%5B%5D=49554', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5342763', 'pdf_url': 'https://europepmc.org/articles/pmc5342763?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342763', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27689328', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.12310', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=12310&path%5B%5D=49554', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.8, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 69, 'referenced_works': ['https://openalex.org/W100143147', 'https://openalex.org/W1157462478', 'https://openalex.org/W1529553588', 'https://openalex.org/W1536812836', 'https://openalex.org/W1574080856', 'https://openalex.org/W1581834767', 'https://openalex.org/W1821453853', 'https://openalex.org/W1881326048', 'https://openalex.org/W1965881928', 'https://openalex.org/W1968172616', 'https://openalex.org/W1979945039', 'https://openalex.org/W1980496921', 'https://openalex.org/W1987170068', 'https://openalex.org/W1989272546', 'https://openalex.org/W2009858080', 'https://openalex.org/W2017329417', 'https://openalex.org/W2018446432', 'https://openalex.org/W2021536610', 'https://openalex.org/W2024732985', 'https://openalex.org/W2032729457', 'https://openalex.org/W2033613284', 'https://openalex.org/W2041034966', 'https://openalex.org/W2042599791', 'https://openalex.org/W2047428811', 'https://openalex.org/W2049140983', 'https://openalex.org/W2053116646', 'https://openalex.org/W2054621094', 'https://openalex.org/W2055346449', 'https://openalex.org/W2064522668', 'https://openalex.org/W2076047768', 'https://openalex.org/W2077356336', 'https://openalex.org/W2078576279', 'https://openalex.org/W2080226816', 'https://openalex.org/W2084826637', 'https://openalex.org/W2085139841', 'https://openalex.org/W2085615042', 'https://openalex.org/W2089518544', 'https://openalex.org/W2095873383', 'https://openalex.org/W2098725729', 'https://openalex.org/W2105613536', 'https://openalex.org/W2106714719', 'https://openalex.org/W2109674742', 'https://openalex.org/W2114770772', 'https://openalex.org/W2116708359', 'https://openalex.org/W2117977572', 'https://openalex.org/W2119834552', 'https://openalex.org/W2128403571', 'https://openalex.org/W2130239280', 'https://openalex.org/W2130955565', 'https://openalex.org/W2133148543', 'https://openalex.org/W2134629862', 'https://openalex.org/W2148416479', 'https://openalex.org/W2149244210', 'https://openalex.org/W2150039609', 'https://openalex.org/W2150457305', 'https://openalex.org/W2150627722', 'https://openalex.org/W2151370330', 'https://openalex.org/W2153234291', 'https://openalex.org/W2156162122', 'https://openalex.org/W2158217645', 'https://openalex.org/W2161222316', 'https://openalex.org/W2161879447', 'https://openalex.org/W2168158865', 'https://openalex.org/W2168428430', 'https://openalex.org/W2176456200', 'https://openalex.org/W2235523093', 'https://openalex.org/W2296253991', 'https://openalex.org/W285746480', 'https://openalex.org/W834730509'], 'related_works': ['https://openalex.org/W4361842367', 'https://openalex.org/W4361842353', 'https://openalex.org/W3018385559', 'https://openalex.org/W3005243004', 'https://openalex.org/W2809932017', 'https://openalex.org/W2372172309', 'https://openalex.org/W2352173395', 'https://openalex.org/W2138032728', 'https://openalex.org/W2074215098', 'https://openalex.org/W2066025570'], 'abstract_inverted_index': {'//': [0], 'Peterson': [1], 'Kariuki': [2], 'Maina': [3], '1,': [4, 9], '*': [5, 10, 93], ',': [6, 11, 15, 19, 23, 27, 31], 'Peng': [7], 'Shao': [8], 'Qi': [12, 34], 'Liu': [13], '1': [14, 22, 35, 36], 'Ladan': [16], 'Fazli': [17], '2': [18, 30, 55], 'Scott': [20], 'Tyler': [21], 'Moman': [24], 'Nasir': [25], '3': [26, 72], 'Xuesen': [28], 'Dong': [29], 'Hank': [32, 104], 'Heng': [33, 105], 'Department': [37, 59, 73], 'of': [38, 45, 48, 60, 64, 74, 80, 86, 164, 172, 222, 232, 245, 265, 309, 322], 'Anatomy': [39], 'and': [40, 76, 83, 147, 157, 166, 181, 197, 210, 243, 262, 274, 311, 315, 318], 'Cell': [41], 'Biology,': [42], 'Carver': [43], 'College': [44, 79], 'Medicine,': [46], 'University': [47, 63, 85], 'Iowa,': [49, 87], 'Iowa': [50, 88], 'City,': [51, 89], 'IA': [52, 90], '52246,': [53], 'USA': [54, 92], 'Vancouver': [56], 'Prostate': [57], 'Center,': [58], 'Urology': [61], 'Sciences,': [62, 84], 'British': [65], 'Columbia,': [66], 'Vancouver,': [67], 'BC': [68], 'V6H': [69], '3Z6,': [70], 'Canada': [71], 'Health': [75], 'Human': [77], 'Physiology,': [78], 'Liberal': [81], 'Arts': [82], '52242,': [91], 'These': [94], 'authors': [95], 'have': [96], 'contributed': [97], 'equally': [98], 'to': [99, 143, 160, 295], 'this': [100, 194], 'work': [101], 'Correspondence': [102], 'to:': [103], 'Qi,': [106], 'email:': [107], '[email protected]': [108], 'Keywords:': [109], 'prostate': [110, 135, 247], 'cancer,': [111], 'NED,': [112], 'CRPC,': [113, 167, 317], 'PHF8,': [114], 'c-MYC': [115, 203], 'Received:': [116], 'May': [117], '02,': [118], '2016': [119, 123, 127], 'Accepted:': [120], 'September': [121, 125], '20,': [122], 'Published:': [124], '28,': [126], 'ABSTRACT': [128], 'Epigenetic': [129], 'factors': [130, 174], 'play': [131], 'critical': [132], 'roles': [133], 'in': [134, 183, 227, 236, 251, 271, 316, 328], 'cancer': [136], '(PCa)': [137], 'development.': [138], 'However,': [139], 'how': [140], 'they': [141], 'contribute': [142], 'neuroendocrine': [144], 'differentiation': [145], '(NED)': [146], 'castration-resistant': [148], 'PCa': [149, 249], '(CRPC)': [150], 'is': [151, 177, 220], 'not': [152], 'fully': [153], 'understood.': [154], 'Using': [155], 'bioinformatics': [156], 'biochemical': [158], 'approaches': [159], 'analyze': [161], 'cell-based': [162], 'models': [163], 'NED': [165, 180, 314], 'we': [168], 'found': [169, 215], 'a': [170, 187, 252, 325], 'cluster': [171], 'epigenetic': [173], 'whose': [175], 'expression': [176], 'downregulated': [178], 'during': [179, 248, 313], 'upregulated': [182], 'CRPC': [184, 228, 238, 272], '(i.e.': [185], 'follow': [186], 'Down-Up': [188], 'pattern).': [189], 'Two': [190], 'histone': [191], 'demethylases': [192], 'within': [193], 'cluster,': [195], 'PHF8': [196, 209, 233, 261, 266, 290, 310, 323], 'KDM3A,': [198], 'are': [199], 'post-transcriptionally': [200], 'regulated': [201], 'by': [202], 'through': [204], 'miR-22,': [205], 'which': [206], 'targets': [207], 'both': [208], 'KDM3A': [211, 312], '.': [212], 'We': [213], 'also': [214], 'that': [216, 305], 'the': [217, 246, 258, 284, 296, 307, 320], 'c-MYC/miR-22/PHF8': [218], 'axis': [219], 'downstream': [221], 'androgen': [223], 'receptor': [224], '(AR)': [225], 'signaling': [226], 'cells.': [229], 'The': [230], 'co-expression': [231], 'with': [234], 'AR': [235, 297], 'clinical': [237], 'samples,': [239], 'normal': [240], 'mouse': [241, 255], 'prostate,': [242], 'adenocarcinomas': [244], 'progression': [250, 270], 'transgenic': [253], '(TRAMP)': [254], 'model': [256], 'supports': [257], 'connection': [259], 'between': [260], 'AR.': [263], 'Knockdown': [264], 'impedes': [267], 'cell': [268, 287], 'cycle': [269], 'cells': [273, 294], 'has': [275], 'more': [276], 'profound': [277], 'effects': [278], 'on': [279, 283], 'their': [280], 'growth': [281], 'than': [282], 'parental': [285], 'LNCaP': [286], 'line.': [288], 'Furthermore,': [289], 'knockdown': [291], 'sensitizes': [292], 'LNCaP-Abl': [293], 'antagonist': [298], 'enzalutamide.': [299], 'Our': [300], 'data': [301], 'reveal': [302], 'novel': [303], 'mechanisms': [304], 'underlie': [306], 'regulation': [308], 'support': [319], 'candidacy': [321], 'as': [324], 'therapeutic': [326], 'target': [327], 'CRPC.': [329]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2442109640', 'counts_by_year': [{'year': 2024, 'cited_by_count': 9}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 3}], 'updated_date': '2024-12-12T03:23:04.461211', 'created_date': '2016-06-24'}