Title: [Studies on the inhibitory effects of tea polyphenols and tea pigments on liver precancerous lesion in rats].
Abstract: The chemopreventive effects of tea polyphenols and tea pigments on liver precancerous lesion in rats were investigated. The results showed that the density and area of GST-P in the tea-treated groups were significantly reduced as compared with the positive control group. Furthermore, tea polyphenols and tea pigments induced the expression of p21WAF1 protein, inhibited the expression of Bcl-2 protein and induced the expression of Bax protein. It is concluded that GST-P was significantly inhibited by tea polyphenols and tea pigments and inhibition of cell proliferation and induction of apoptosis may be the two important mechanisms.
Publication Year: 2001
Publication Date: 2001-05-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 2
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