Publication Information

{'id': 'https://openalex.org/W2429522722', 'doi': 'https://doi.org/10.1016/j.jhep.2016.06.009', 'title': 'Unexpected high incidence of hepatocellular carcinoma in cirrhotic patients with sustained virologic response following interferon-free direct-acting antiviral treatment', 'display_name': 'Unexpected high incidence of hepatocellular carcinoma in cirrhotic patients with sustained virologic response following interferon-free direct-acting antiviral treatment', 'publication_year': 2016, 'publication_date': '2016-06-27', 'ids': {'openalex': 'https://openalex.org/W2429522722', 'doi': 'https://doi.org/10.1016/j.jhep.2016.06.009', 'mag': '2429522722', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27318327'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.jhep.2016.06.009', 'pdf_url': 'http://www.journal-of-hepatology.eu/article/S0168827816302719/pdf', 'source': {'id': 'https://openalex.org/S83651209', 'display_name': 'Journal of 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'(94)': [846], 'two-fold': [850], 'increase': [851, 878], 'rates': [854], 'Japanese': [856], 'as': [862, 960, 1672, 1754, 1756, 1801, 1803, 1924, 1926], 'compared': [863, 1062, 1278], 'IFN/RBV': [865, 1034, 1208], '[[4]Toyoda': [867], 'H.': [868, 1042, 1608], 'Kumada': [869], 'T.': [870, 872], 'Tada': [871], 'Changes': [873], 'backgrounds': [876], 'may': [877, 1477, 1486, 1670, 1707, 1758], 'HCV.Hepatology.': [892], '(e-pub)https://doi.org/10.1002/hep.28632Crossref': [894], '(30)': [897], 'explained': [901], 'higher': [904, 1020], 'age': [905], 'more': [907, 970], 'disease.': [912], 'present': [915], 'study': [916, 2096], 'only': [917, 1745], 'B': [927], 'Calculating': [932], 'frequency': [934, 1001, 1025], 'our': [938], 'difficult.': [941], 'Using': [942], '182': [944], 'AURIC': [945, 1007], 'completing': [947], 'weeks': [949, 1011], 'follow-up': [951, 1216], 'developing': [953, 1736], 'denominator,': [961], 'rate': [964], '8.1%': [966], '(16/198).': [967], 'By': [968], 'conservative': [971], 'estimate': [972], 'excluding': [974], 'HCC)': [982], 'it': [983, 1018, 1327], 'would': [984], '6.6%': [986], 'overall': [987], '(13/195)': [988], '5.2%': [990], '(10/192': [991], 'SVR).': [995], 'We': [996], 'hope': [997], 'that': [998, 1263, 1331, 1559], 'real': [1000], 'will': [1002], 'lower': [1004], 'when': [1005], 'completed': [1009], 'follow-up.': [1013], 'Whatever': [1014], 'used,': [1017], 'than': [1021], 'estimated': [1023], '1%/year': [1024], 'dual': [1035], '[5van': [1037], 'der': [1038], 'Meer': [1039], 'A.J.': [1040], 'Wedemeyer': [1041], 'Feld': [1043], 'J.J.': [1044], 'Dufour': [1045], 'J.F.': [1046, 1656], 'Zeuzem': [1047], 'Hansen': [1049], 'B.E.': [1050], 'al.Life': [1052], 'expectancy': [1053], 'chronic': [1057, 1101, 1360], 'infection': [1059, 1364], 'general': [1065], 'population.JAMA.': [1066], '2014;': [1067, 1308, 1422], '312:': [1068], '1927-1928Crossref': [1069], '(78)': [1072], 'Scholar,': [1074, 1113, 1160, 1429, 1540, 1573, 1606], '6Rutter': [1075], 'K.': [1076, 1406, 1435, 1506], 'Stättermayer': [1077, 1785], 'A.F.': [1078], 'Beinhardt': [1079], 'Scherzer': [1081], 'T.M.': [1082], 'Steindl-Munda': [1083], 'P.': [1084], 'Trauner': [1085], 'al.Successful': [1088, 1356], 'improves': [1091], 'survival': [1092], 'due': [1099], 'C.Aliment': [1103], 'Pharmacol': [1104], 'Ther.': [1105], '2015;': [1106, 1370], '41:': [1107], '521-531Crossref': [1108], '(34)': [1111], '7Di': [1114], 'V.': [1116, 1118, 1301], 'Calvaruso': [1117], 'Ferraro': [1119], 'D.': [1120, 1400, 1404, 1408, 1437, 1502], 'Bavetta': [1121], 'M.G.': [1122], 'Cabibbo': [1123], 'G.': [1124, 1508, 1616], 'Conte': [1125], 'E.': [1126, 1344, 1662], 'al.Effects': [1128], 'viral': [1130, 1496, 1515], 'differ': [1138], 'portal': [1142], 'hypertension.Gastroenterology.': [1143], '(pii:': [1145], 'S0016-5085(16)30049-X.': [1146], '[Epub': [1147], 'ahead': [1148, 1191, 1253, 1602, 1695], 'print])https://doi.org/10.1053/j.gastro.2016.03.036Abstract': [1150], '(109)': [1158], '8Lu': [1161], 'Li': [1163, 1225, 1580], 'Rupp': [1165, 1227], 'L.B.': [1166, 1228], 'Holmberg': [1167, 1229], 'S.D.': [1168, 1230], 'Moorman': [1169, 1231], 'A.C.': [1170, 1232], 'Spradling': [1171, 1233], 'P.R.': [1172, 1234], 'al.CHeCS': [1174, 1236], 'InvestigatorsHepatitis': [1175, 1237], 'failure': [1178, 1240], 'associated': [1180, 1242], 'carcinoma.J': [1186, 1248], 'Viral': [1187, 1249, 1463], 'Hepat.': [1188, 1250, 1464], '([Epub': [1190, 1252, 1601, 1694], 'print])https://doi.org/10.1111/jvh.12538Crossref': [1193, 1255], '(29)': [1195, 1257], 'Of': [1198], '94': [1200], '10': [1209], 'mean': [1215], '7.8': [1218], 'Fig.': [1221], '1)': [1222], '[[8]Lu': [1223], 'explanations': [1261], 'major': [1264], 'mechanisms': [1265], 'regeneration': [1267], 'stimulated': [1269, 1395], 'curing': [1271], 'inflammation,': [1272], 'changed': [1275], 'immunologic': [1276], 'environment': [1277], 'IFN-containing': [1282], 'treatments': [1283], 'leading': [1284], 'growth': [1286, 1479, 1629], 'precancerous': [1288], 'lesions': [1289], 'malignant': [1293, 1481], 'cell': [1294, 1368], 'clones': [1295], '[[9]Bruix': [1296], 'Gores': [1298], 'G.J.': [1299], 'Mazzaferro': [1300], 'Hepatocellular': [1302], 'clinical': [1304], 'frontiers': [1305], 'perspectives.Gut.': [1307], '63:': [1309], '844-855Crossref': [1310], '(1073)': [1313], 'Interferon': [1316], 'immune': [1319], 'modulator': [1320], 'anti-proliferative': [1322], 'properties.': [1323], 'With': [1324], 'treatments,': [1326], 'has': [1328], 'been': [1329], 'shown': [1330], 'rapid': [1333], 'disappearance': [1334], 'leads': [1337], 'reconstitution': [1339], 'innate': [1341], 'immunity': [1342], '[[10]Serti': [1343], 'Chepa-Lotrea': [1345], 'X.': [1346, 1581], 'Y.J.': [1348], 'Keane': [1349], 'Fryzek': [1351], 'N.': [1352], 'Liang': [1353], 'T.J.': [1354], 'normalizes': [1365], 'natural': [1366], 'killer': [1367], 'function.Gastroenterology.': [1369], '149:': [1371], '190-200Abstract': [1372], '(194)': [1380], 'downregulation': [1384], 'type': [1386], 'II': [1387], 'III': [1389], 'IFNs,': [1390], 'receptors,': [1392], 'genes': [1396], '[11Meissner': [1397], 'E.G.': [1398, 1431], 'Wu': [1399], 'Osinusi': [1401], 'Bon': [1403], 'Virtaneva': [1405, 1434], 'Sturdevant': [1407, 1436], 'al.Endogenous': [1410], 'intrahepatic': [1411, 1561], 'IFNs': [1412], 'association': [1414], 'outcome.J': [1419], 'Clin': [1420], 'Invest.': [1421], '124:': [1423], '3352-3363Crossref': [1424], '(166)': [1427], '12Meissner': [1430], 'Kohli': [1432], 'Martens': [1438], 'Porcella': [1440], 'S.F.': [1441], 'al.Achieving': [1443], 'correlates': [1453], 'hepatic': [1455], 'gene': [1457], 'expression': [1458], 'changes': [1459], 'independent': [1460], 'cirrhosis.J': [1462], 'https://doi.org/10.1111/jvh.12510Crossref': [1466], '(32)': [1469], 'lack': [1473], 'activation': [1476], 'allow': [1478], 'cells.': [1482], 'Another': [1483], 'factor': [1484], 'involved': [1485], 'miR-122,': [1488], 'plays': [1490], 'central': [1492, 2045], 'role': [1493], 'suppressing': [1495], 'replication': [1497, 1516], 'controlling': [1499], 'hepatocarcinogenesis': [1500], '[13Harouaka': [1501], 'Engle': [1503], 'R.E.': [1504], 'Wollenberg': [1505], 'Diaz': [1507], 'Tice': [1509], 'A.B.': [1510], 'Zamboni': [1511], 'F.': [1512, 1784, 2073], 'al.Diminished': [1514], 'compartmentalization': [1518], 'tissue.Proc': [1526], 'Natl': [1527], 'Acad': [1528], 'Sci': [1529], 'U': [1530], 'S': [1531], '113:': [1534], '1375-1380Crossref': [1535], '(44)': [1538], '14Tsai': [1541], 'W.C.': [1542], 'Hsu': [1543], 'P.W.': [1544], 'Lai': [1545], 'T.C.': [1546], 'Chau': [1547], 'G.Y.': [1548], 'Lin': [1549], 'C.W.': [1550], 'Chen': [1551, 1582], 'C.M.': [1552], 'al.MicroRNA-122,': [1554], 'suppressor': [1557], 'microRNA': [1558], 'regulates': [1560], 'carcinoma.Hepatology.': [1565], '2009;': [1566], '49:': [1567], '1571-1582Crossref': [1568], '(511)': [1571], '15Li': [1574], 'Deng': [1576], 'Hu': [1578], 'Ju': [1584], 'Y.': [1585], 'al.Chronic': [1587], 'inflammation': [1588], 'contributes': [1589], 'development': [1592, 1761], 'decreasing': [1597], 'miR-122': [1598, 1645, 1669, 1689], 'levels.Oncotarget.': [1599], 'print])https://doi.org/10.18632/oncotarget.7740Crossref': [1604, 1697], '16Jialin': [1607], 'Kai': [1609], 'Lu': [1611], 'Xu': [1613], 'Zhizhen': [1614], 'Wei': [1615], 'Shan': [1617], 'al.Upregulation': [1620], 'microRNA-122': [1622], 'farnesoid': [1624], 'X': [1625], 'receptor': [1626], 'suppresses': [1627], 'cells.Infect': [1633], 'Agent': [1634], 'Cancer.': [1635], '11': [1637], '([eCollection]):': [1638], '9https://doi.org/10.1186/s13027-016-0056-yCrossref': [1639], '(4)': [1642], 'concentrations': [1646], 'decrease': [1647], 'therapy,': [1651], '[[17]Waring': [1655], 'Dumas': [1657], 'E.O.': [1658], 'Abel': [1659], 'Coakley': [1661], 'Cohen': [1663], 'D.E.': [1664], 'Davis': [1665], 'J.W.': [1666], 'al.Serum': [1668], 'serve': [1671], 'biomarker': [1674], 'antivirals:': [1680], 'effect': [1681], 'paritaprevir/R': [1683], 'dasabuvir': [1685], 'ombitasvir': [1687], 'HCV-infected': [1691], 'subjects.Oncotarget.': [1692], '(52)': [1700], 'If': [1703], 'confirmed,': [1704], 'important': [1710, 2091], 'implication.': [1711], 'Patients': [1712], 'should': [1715], 'undergo': [1716], 'regular': [1717], 'screening': [1719], 'achieving': [1721], 'SVR.': [1722], 'orthotopic': [1727], 'transplantation': [1729], '(OLT)': [1730], 'waiting': [1731], 'list': [1732], 'could': [1739], 'argument': [1741], 'treating': [1743, 1751], 'successful': [1747], 'transplantation.': [1748], 'contrast,': [1750], 'non-cirrhotic': [1752], 'prevent': [1759], 'Karin': [1764, 2036], 'Kozbial,': [1765], 'Stephan': [1766], 'Moser,': [1767, 2050], 'Remy': [1768, 2051], 'Schwarzer,': [1769, 2052], 'Hermann': [1770, 2053], 'Laferl,': [1771, 2054], 'Ramona': [1772, 2055], 'El-Zoairy,': [1773], 'Sandra': [1774, 2059], 'Beinhardt,': [1775, 2060], 'Clarissa': [1776, 2063], 'Freissmuth,': [1777, 2064], 'Michael': [1778, 1875, 1941, 2065, 2077, 2081], 'Strasser:': [1779], 'nothing': [1780], 'disclose.': [1782], 'Albert': [1783, 2072], 'received': [1786, 1815, 1840, 1853, 1877, 1901, 1943, 1976, 2025], 'honoraria': [1787, 1908, 1951], 'consulting': [1789, 1913, 1953], 'Gilead,': [1791, 1809, 1821, 1830, 1848, 1861, 1872, 1885, 1896, 1904, 1920, 1936, 1958, 1970, 1984, 1995, 2010, 2017, 2033], 'payments': [1792, 1927, 1964], 'lectures': [1794, 1929, 1966], 'Boehringer': [1796, 1916, 1932], 'Ingelheim,': [1797, 1917, 1933], 'Janssen,': [1798, 1810, 1937, 1959], 'Roche,': [1800, 1907, 2011, 2023], 'well': [1802, 1925], 'travel': [1804], 'support': [1805], 'Bristol-Myerss': [1807, 1918, 1934], 'Squibb,': [1808, 1919, 1935], 'Roche.': [1812, 1940, 1973], 'Rudolf': [1813, 2057], 'Stauber:': [1814], 'lecture': [1816, 1841, 1854, 1878, 1977, 2026], 'fees': [1817, 1842, 1855, 1879, 1978, 2027], 'AbbVie,': [1819, 1828, 1844, 1857, 1868, 1881, 1892, 1915, 1931, 1956, 1980, 1991, 2008, 2029], 'BMS,': [1820, 1829, 1968, 2009, 2019], 'Merz;': [1823], 'advisory': [1824, 1864, 1888, 1987], 'board': [1825, 1865, 1889, 1910, 1988], 'member': [1826, 1866, 1890, 1989], 'of:': [1827, 1867, 1891, 1990], 'MSD,': [1832, 1845, 1858, 1869, 1882, 1893, 1923, 1949, 1960, 1981, 1992, 2018, 2030], 'unrestricted': [1833, 1998, 2020], 'research': [1834, 1999, 2021], 'grant:': [1835, 2022], 'Abbvie,': [1836, 2016], 'MSD.': [1837], 'Ivo': [1838, 2061], 'Graziadei:': [1839], 'Bristol': [1846, 1859, 1870, 1883, 1894, 1982, 1993, 2031], 'Myers-Squibb,': [1847, 1860, 1871, 1884, 1895, 1983, 1994, 2032], 'Janssen.': [1850, 1874, 1898, 2035], 'Andreas': [1851, 2067], 'Maieron:': [1852, 2068], 'Janssen;': [1863, 1887, 1986, 1997], 'Gschwantler:': [1876], 'Markus': [1899, 2079], 'Peck-Radosalvjevic:': [1900], 'grants': [1902, 1944], 'MSD': [1905, 1938, 1971], 'membership': [1911], 'Janssen': [1921], 'Trauner:': [1942], 'Albireo,': [1946, 1955], 'Falk,': [1947, 1957, 1969], 'Intercept,': [1948], 'Takeda,': [1950], 'Phenex,': [1961], 'Novartis,': [1963], 'Harald': [1974, 2083], 'Hofer:': [1975, 2084], 'grant': [2000], 'AbbVie.': [2002], 'Peter': [2003, 2094], 'Ferenci:': [2004, 2095], 'Advisory': [2005], 'board:': [2006], 'Merck,': [2007], 'Wilson': [2012], 'Therapeutics,': [2013], 'Speaker': [2014], 'bureau:': [2015], 'Gilead;': [2024], 'collected': [2038], 'data,': [2040, 2104], 'maintained': [2041], 'updated': [2043], 'database,': [2046], 'data': [2047, 2075], 'analysis.': [2048], 'Stefan': [2049], 'Al-Zoairy,': [2056], 'Stauber,': [2058], 'Graziadei,': [2062], 'Strasser,': [2066], 'acquisition': [2069], 'data.': [2071], 'Stättermayer:': [2074], 'analysis,': [2076], 'Gschwantler,': [2078], 'Peck-Radosalvjevic,': [2080], 'Trauner,': [2082], 'critical': [2085], 'revision': [2086], 'manuscript': [2089], 'intellectual': [2092], 'content.': [2093], 'concept': [2097], 'design,': [2099], 'analysis': [2100], 'interpretation': [2102], 'writing': [2105], 'manuscript.': [2108], 'Download': [2109], '.pdf': [2110], '(.04': [2111], 'MB)': [2112], 'Help': [2113], 'pdf': [2115], 'files': [2116]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2429522722', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 16}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 27}, {'year': 2020, 'cited_by_count': 29}, {'year': 2019, 'cited_by_count': 29}, {'year': 2018, 'cited_by_count': 47}, {'year': 2017, 'cited_by_count': 39}, {'year': 2016, 'cited_by_count': 13}], 'updated_date': '2024-12-11T02:30:39.741017', 'created_date': '2016-06-24'}