Publication Information

{'id': 'https://openalex.org/W2428933557', 'doi': None, 'title': '[Transformation of the substrate specificity of EcoRI restrictase under the influence of glycerin].', 'display_name': '[Transformation of the substrate specificity of EcoRI restrictase under the influence of glycerin].', 'publication_year': 1977, 'publication_date': '1977-07-01', 'ids': {'openalex': 'https://openalex.org/W2428933557', 'mag': '2428933557', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/329915'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/329915', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5015106322', 'display_name': 'Karamov Ev', 'orcid': 'https://orcid.org/0000-0003-1162-118X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Karamov Ev', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006514069', 'display_name': 'Naroditskiĭ Bs', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Naroditskiĭ Bs', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042133318', 'display_name': 'Boris Zavizion', 'orcid': 'https://orcid.org/0000-0001-7246-4179'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Zavizion Ba', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5078273554', 'display_name': 'Tikhonenko Ti', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Tikhonenko Ti', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 55}, 'biblio': {'volume': '84', 'issue': '7', 'first_page': '46', 'last_page': '8'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10932', 'display_name': 'Microbial Metabolic Engineering and Bioproduction', 'score': 0.9254, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10932', 'display_name': 'Microbial Metabolic Engineering and Bioproduction', 'score': 0.9254, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C130123407', 'wikidata': 'https://www.wikidata.org/wiki/Q417754', 'display_name': 'EcoRI', 'level': 4, 'score': 0.9933475}, {'id': 'https://openalex.org/C128319531', 'wikidata': 'https://www.wikidata.org/wiki/Q219715', 'display_name': 'Restriction enzyme', 'level': 3, 'score': 0.79064584}, {'id': 'https://openalex.org/C2780881558', 'wikidata': 'https://www.wikidata.org/wiki/Q132501', 'display_name': 'Glycerol', 'level': 2, 'score': 0.63830066}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.6380994}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.58820945}, {'id': 'https://openalex.org/C204241405', 'wikidata': 'https://www.wikidata.org/wiki/Q461499', 'display_name': 'Transformation (genetics)', 'level': 3, 'score': 0.5797167}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.53127635}, {'id': 'https://openalex.org/C94412978', 'wikidata': 'https://www.wikidata.org/wiki/Q103135', 'display_name': 'Hydrolysis', 'level': 2, 'score': 0.523141}, {'id': 'https://openalex.org/C187428577', 'wikidata': 'https://www.wikidata.org/wiki/Q898396', 'display_name': 'Ionic strength', 'level': 3, 'score': 0.518684}, {'id': 'https://openalex.org/C151292725', 'wikidata': 'https://www.wikidata.org/wiki/Q285967', 'display_name': 'HindIII', 'level': 4, 'score': 0.4728494}, {'id': 'https://openalex.org/C2777028655', 'wikidata': 'https://www.wikidata.org/wiki/Q415601', 'display_name': 'Endonuclease', 'level': 3, 'score': 0.4495694}, {'id': 'https://openalex.org/C2777289219', 'wikidata': 'https://www.wikidata.org/wiki/Q7632154', 'display_name': 'Substrate (aquarium)', 'level': 2, 'score': 0.41559404}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.39368275}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.35258394}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.22349092}, {'id': 'https://openalex.org/C184651966', 'wikidata': 'https://www.wikidata.org/wiki/Q906356', 'display_name': 'Aqueous solution', 'level': 2, 'score': 0.14707792}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.1386286}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.096567005}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004262', 'descriptor_name': 'DNA Restriction Enzymes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004720', 'descriptor_name': 'Endonucleases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D005990', 'descriptor_name': 'Glycerol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000260', 'descriptor_name': 'Adenoviruses, Human', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000260', 'descriptor_name': 'Adenoviruses, Human', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D002384', 'descriptor_name': 'Catalysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003090', 'descriptor_name': 'Coliphages', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004279', 'descriptor_name': 'DNA, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/329915', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W293310242', 'https://openalex.org/W2428933557', 'https://openalex.org/W2393037180', 'https://openalex.org/W239262219', 'https://openalex.org/W2244509640', 'https://openalex.org/W2169756550', 'https://openalex.org/W2006353620', 'https://openalex.org/W1967298302', 'https://openalex.org/W1576007024', 'https://openalex.org/W139813698'], 'abstract_inverted_index': {'The': [0, 37, 85], 'restriction': [1, 31, 106], 'endonuclease': [2], 'EcoRI': [3, 38, 90], 'hydrolyzes': [4], 'DNA': [5], 'to': [6, 24, 74, 93, 101], 'a': [7], 'greater': [8], 'number': [9], 'of': [10, 15, 30, 48, 55, 81, 103], 'fragments': [11], 'in': [12, 41], 'the': [13, 27, 45, 49, 56, 65, 82, 89, 104], 'presence': [14], 'glycerol': [16, 33], 'than': [17], 'under': [18, 61], 'normal': [19], 'conditions.': [20], 'This': [21], 'enzyme': [22, 66], 'begins': [23], 'work': [25], 'by': [26], 'so-called': [28], 'EcoRI-type': [29], 'when': [32, 44], 'concentration': [34], 'reaches': [35], '50%.': [36], 'activity': [39, 91], 'appeared': [40], 'experiments': [42], 'only': [43], 'ionic': [46], 'strength': [47], 'solution': [50, 57], 'was': [51, 58, 67, 72], 'decreased': [52], 'and': [53, 70], 'pH': [54], 'increased.': [59], 'However,': [60], 'such': [62], 'extreme': [63], 'conditions': [64, 87], 'quickly': [68], 'inactivated': [69], 'it': [71], 'difficult': [73], 'obtain': [75, 94], 'reproducible': [76, 95], 'results': [77], 'especially': [78], 'for': [79, 88], 'hydrolysis': [80], 'high-molecular': [83], 'DNA.': [84], 'suggested': [86], 'permit': [92], 'results,': [96], 'this': [97], 'being': [98], 'practically': [99], 'equivalent': [100], 'discovery': [102], 'new': [105], 'endonuclease.': [107]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2428933557', 'counts_by_year': [], 'updated_date': '2024-12-10T23:50:38.766453', 'created_date': '2016-06-24'}