Publication Information

{'id': 'https://openalex.org/W2419359170', 'doi': None, 'title': '[Selection of one of the TNF blockers; infliximab and etanercept].', 'display_name': '[Selection of one of the TNF blockers; infliximab and etanercept].', 'publication_year': 2007, 'publication_date': '2007-07-01', 'ids': {'openalex': 'https://openalex.org/W2419359170', 'mag': '2419359170', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17642244'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17642244/', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080767944', 'display_name': 'Toshihide Mimura', 'orcid': 'https://orcid.org/0000-0002-9050-0855'}, 'institutions': [{'id': 'https://openalex.org/I8588240', 'display_name': 'Saitama Medical University', 'ror': 'https://ror.org/04zb31v77', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I8588240']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Toshihide Mimura', 'raw_affiliation_strings': ['Division of Rheumatology and Applied Immunology, Department of Internal Medicine, Saitama Medical University.'], 'affiliations': [{'raw_affiliation_string': 'Division of Rheumatology and Applied Immunology, Department of Internal Medicine, Saitama Medical University.', 'institution_ids': ['https://openalex.org/I8588240']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5080767944'], 'corresponding_institution_ids': ['https://openalex.org/I8588240'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.512355, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 70, 'max': 73}, 'biblio': {'volume': '65', 'issue': '7', 'first_page': '1282', 'last_page': '1286'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11725', 'display_name': 'Immunodeficiency and Autoimmune Disorders', 'score': 0.9766, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11725', 'display_name': 'Immunodeficiency and Autoimmune Disorders', 'score': 0.9766, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10200', 'display_name': 'Rheumatoid Arthritis Research and Therapies', 'score': 0.9492, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11157', 'display_name': 'Chronic Lymphocytic Leukemia Research', 'score': 0.9407, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2777226972', 'wikidata': 'https://www.wikidata.org/wiki/Q415343', 'display_name': 'Etanercept', 'level': 3, 'score': 0.97619534}, {'id': 'https://openalex.org/C2777138892', 'wikidata': 'https://www.wikidata.org/wiki/Q415264', 'display_name': 'Infliximab', 'level': 3, 'score': 0.90491676}, {'id': 'https://openalex.org/C17991360', 'wikidata': 'https://www.wikidata.org/wiki/Q21173843', 'display_name': 'Tumor necrosis factor alpha', 'level': 2, 'score': 0.8214989}, {'id': 'https://openalex.org/C2777575956', 'wikidata': 'https://www.wikidata.org/wiki/Q187255', 'display_name': 'Rheumatoid arthritis', 'level': 2, 'score': 0.75542545}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7094353}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.51844025}, {'id': 'https://openalex.org/C2781059491', 'wikidata': 'https://www.wikidata.org/wiki/Q422232', 'display_name': 'Methotrexate', 'level': 2, 'score': 0.46246594}, {'id': 'https://openalex.org/C2777077863', 'wikidata': 'https://www.wikidata.org/wiki/Q170990', 'display_name': 'Arthritis', 'level': 2, 'score': 0.4572224}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.44474235}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.38746375}], 'mesh': [{'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D018501', 'descriptor_name': 'Antirheumatic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D007074', 'descriptor_name': 'Immunoglobulin G', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D018124', 'descriptor_name': 'Receptors, Tumor Necrosis Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D018501', 'descriptor_name': 'Antirheumatic Agents', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000068800', 'descriptor_name': 'Etanercept', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007074', 'descriptor_name': 'Immunoglobulin G', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000069285', 'descriptor_name': 'Infliximab', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008727', 'descriptor_name': 'Methotrexate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008727', 'descriptor_name': 'Methotrexate', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D018124', 'descriptor_name': 'Receptors, Tumor Necrosis Factor', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17642244/', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17642244', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.81}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W940714784', 'https://openalex.org/W3129703953', 'https://openalex.org/W2968128868', 'https://openalex.org/W2560305371', 'https://openalex.org/W2421832289', 'https://openalex.org/W2419097680', 'https://openalex.org/W2418428029', 'https://openalex.org/W2417817637', 'https://openalex.org/W2404219601', 'https://openalex.org/W2396787319', 'https://openalex.org/W2345141018', 'https://openalex.org/W2339178683', 'https://openalex.org/W2325764353', 'https://openalex.org/W2160832116', 'https://openalex.org/W2143239720', 'https://openalex.org/W2114241305', 'https://openalex.org/W2063127930', 'https://openalex.org/W2052067610', 'https://openalex.org/W1977786371', 'https://openalex.org/W1976378231'], 'abstract_inverted_index': {'Infliximab': [0], 'and': [1, 23, 26, 47, 109], 'etanercept,': [2], 'both': [3], 'of': [4, 20, 36, 97, 111], 'which': [5, 62], 'inhibit': [6], 'tumor': [7], 'necrosis': [8], 'factor': [9], '(TNF),': [10], 'show': [11], 'almost': [12], 'an': [13], 'equal': [14], 'efficacy': [15], 'in': [16, 29], 'reducing': [17], 'disease': [18], 'activity': [19], 'rheumatoid': [21], 'arthritis': [22], 'suppressing': [24], 'joints': [25], 'bone': [27], 'destruction': [28], 'the': [30, 54, 81, 106, 112], 'disease.': [31], 'Requiring': [32], 'a': [33, 40, 58, 100], 'concomitant': [34], 'usage': [35], 'methotrexate': [37], '(MTX),': [38], 'infliximab,': [39], 'chimeric': [41], 'antibody': [42], 'against': [43, 88], 'TNF-alpha,': [44], 'blocks': [45, 63], 'TNF-alpha': [46, 49, 64], 'kills': [48], '-producing': [50], 'cells.': [51], 'Etanercept,': [52], 'on': [53, 80, 105], 'other': [55], 'hands,': [56], 'is': [57, 77], 'soluble': [59], 'TNF': [60], 'receptor': [61], 'as': [65, 67], 'well': [66], 'TNF-beta': [68], 'but': [69], 'does': [70], 'not': [71, 78], 'affect': [72], 'cells': [73], 'producing': [74], 'TNF-alpha.': [75], 'MTX': [76], 'required': [79], 'etanercept': [82, 89], 'administration': [83], 'because': [84], 'no': [85], 'neutralizing': [86], 'antibodies': [87], 'are': [90], 'theoretically': [91], 'generated.': [92], 'The': [93], 'strategy': [94], 'selecting': [95], 'one': [96], 'them': [98], 'for': [99], 'patient': [101], 'should': [102], 'be': [103], 'based': [104], 'understanding': [107], 'differences': [108], 'characteristics': [110], 'reagents.': [113]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2419359170', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}], 'updated_date': '2024-12-27T03:33:18.114600', 'created_date': '2016-06-24'}