Title: A significant increase in the in-vitro production of prostaglandin E by ovine cervical tissue at delivery [proceedings].
Abstract: A study of prostaglandin production in vitro by cervical tissue was conducted using a continuous superfusion technique. Prostaglandin F (PGF) and prostaglandin E (PGE) production rates have been obtained from cervical tissue of late-pregnant animals and animals killed after delivery. Highest PGE production rates were found at delivery rather than in tissue from late-pregnant animals; however, there was no production rate difference for PGF. At delivery, PGE production by the cervix is comparable with the production by fetal cotylelon which was known previously to be the major uterine source of PGE. Whether prostaglandins are associated in cervical ripening during labor in unknown, but if prostaglandins are involved then the prostaglandin source may be the cervix.
Publication Year: 1979
Publication Date: 1979-05-01
Language: en
Type: article
Indexed In: ['pubmed']
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