Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2417308765', 'doi': 'https://doi.org/10.1152/ajplegacy.1973.224.5.1195', 'title': 'Length-dependent changes in myocardial contractile state', 'display_name': 'Length-dependent changes in myocardial contractile state', 'publication_year': 1973, 'publication_date': '1973-05-01', 'ids': {'openalex': 'https://openalex.org/W2417308765', 'doi': 'https://doi.org/10.1152/ajplegacy.1973.224.5.1195', 'mag': '2417308765', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/4700639'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajplegacy.1973.224.5.1195', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S204210209', 'display_name': 'American Journal of Physiology-Legacy Content', 'issn_l': '0002-9513', 'issn': ['0002-9513', '2163-5773'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320155', 'host_organization_name': 'American Physiological Society', 'host_organization_lineage': ['https://openalex.org/P4310320155'], 'host_organization_lineage_names': ['American Physiological Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111782154', 'display_name': 'W.W. Parmley', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'WW Parmley', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5074127856', 'display_name': 'Leonard Chuck', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'L Chuck', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.057, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 208, 'citation_normalized_percentile': {'value': 0.996961, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '224', 'issue': '5', 'first_page': '1195', 'last_page': '1199'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9803, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9803, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10821', 'display_name': 'Cardiovascular Function and Risk Factors', 'score': 0.9793, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10882', 'display_name': 'Cardiomyopathy and Myosin Studies', 'score': 0.9555, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/contractility', 'display_name': 'Contractility', 'score': 0.6789166}, {'id': 'https://openalex.org/keywords/cardiovascular-physiology', 'display_name': 'Cardiovascular physiology', 'score': 0.42700422}, {'id': 'https://openalex.org/keywords/cell-physiology', 'display_name': 'Cell Physiology', 'score': 0.4191812}], 'concepts': [{'id': 'https://openalex.org/C39133596', 'wikidata': 'https://www.wikidata.org/wiki/Q5165683', 'display_name': 'Contractility', 'level': 2, 'score': 0.6789166}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5543642}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.51626897}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.45259356}, {'id': 'https://openalex.org/C113217602', 'wikidata': 'https://www.wikidata.org/wiki/Q416781', 'display_name': 'Ryanodine receptor', 'level': 3, 'score': 0.4429704}, {'id': 'https://openalex.org/C183683566', 'wikidata': 'https://www.wikidata.org/wiki/Q5038741', 'display_name': 'Cardiovascular physiology', 'level': 2, 'score': 0.42700422}, {'id': 'https://openalex.org/C191141034', 'wikidata': 'https://www.wikidata.org/wiki/Q3087369', 'display_name': 'Cell physiology', 'level': 3, 'score': 0.4191812}, {'id': 'https://openalex.org/C519063684', 'wikidata': 'https://www.wikidata.org/wiki/Q706', 'display_name': 'Calcium', 'level': 2, 'score': 0.29089963}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.2567583}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.09443483}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010210', 'descriptor_name': 'Papillary Muscles', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001696', 'descriptor_name': 'Biomechanical Phenomena', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002415', 'descriptor_name': 'Cats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000860', 'descriptor_name': 'Hypoxia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000860', 'descriptor_name': 'Hypoxia', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010210', 'descriptor_name': 'Papillary Muscles', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D010210', 'descriptor_name': 'Papillary Muscles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012110', 'descriptor_name': 'Reserpine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012110', 'descriptor_name': 'Reserpine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajplegacy.1973.224.5.1195', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S204210209', 'display_name': 'American Journal of Physiology-Legacy Content', 'issn_l': '0002-9513', 'issn': ['0002-9513', '2163-5773'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320155', 'host_organization_name': 'American Physiological Society', 'host_organization_lineage': ['https://openalex.org/P4310320155'], 'host_organization_lineage_names': ['American Physiological Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4700639', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.74}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4211260839', 'https://openalex.org/W3126616373', 'https://openalex.org/W2777559073', 'https://openalex.org/W2740293592', 'https://openalex.org/W2414101105', 'https://openalex.org/W2113606970', 'https://openalex.org/W2082067206', 'https://openalex.org/W2024007515', 'https://openalex.org/W2013648083', 'https://openalex.org/W1808830836'], 'abstract_inverted_index': {'ARTICLESLength-dependent': [0], 'changes': [1, 1422, 1649, 1665, 1886, 2378, 2423, 2489], 'in': [2, 44, 72, 105, 116, 136, 166, 213, 226, 263, 272, 276, 320, 332, 342, 353, 356, 394, 411, 434, 454, 459, 503, 537, 562, 589, 597, 649, 656, 743, 752, 756, 798, 801, 876, 924, 1000, 1008, 1025, 1078, 1107, 1121, 1130, 1144, 1157, 1174, 1212, 1329, 1355, 1412, 1423, 1433, 1444, 1518, 1545, 1606, 1650, 1666, 1692, 1708, 1735, 1741, 1753, 1761, 1773, 1778, 1791, 1835, 1877, 1887, 1947, 1964, 1974, 1997, 2023, 2059, 2074, 2117, 2155, 2168, 2194, 2242, 2250, 2299, 2333, 2365, 2379, 2387, 2424, 2457, 2490, 2494, 2505, 2526, 2548, 2585, 2636, 2673, 2691, 2743, 2775, 2806], 'myocardial': [3, 334, 677, 834, 879, 1243, 1281, 2166, 2491, 2622], 'contractile': [4, 291, 1829, 2492], 'stateWW': [5], 'Parmley,': [6, 10, 1489], 'and': [7, 11, 61, 103, 121, 130, 188, 209, 219, 322, 329, 340, 344, 358, 366, 386, 462, 473, 484, 514, 540, 565, 599, 614, 623, 638, 659, 690, 701, 721, 732, 740, 774, 785, 794, 803, 821, 858, 917, 993, 1002, 1049, 1059, 1096, 1127, 1132, 1146, 1154, 1159, 1239, 1261, 1272, 1319, 1331, 1379, 1435, 1448, 1471, 1481, 1532, 1581, 1591, 1613, 1710, 1728, 1743, 1763, 1807, 1818, 1833, 1844, 1854, 1879, 1906, 1924, 1935, 1979, 1986, 2005, 2027, 2041, 2050, 2104, 2114, 2121, 2131, 2133, 2177, 2191, 2224, 2232, 2258, 2273, 2316, 2342, 2383, 2394, 2447, 2461, 2474, 2510, 2566, 2592, 2698, 2740, 2762, 2772], 'L': [8, 12], 'ChuckWW': [9], 'ChuckPublished': [13], 'Online:01': [14], 'May': [15, 930, 1584, 2803, 2809], '1973https://doi.org/10.1152/ajplegacy.1973.224.5.1195MoreSectionsPDF': [16], '(1': [17], 'MB)Download': [18], 'PDF': [19, 34], 'ToolsExport': [20], 'citationAdd': [21], 'to': [22, 30, 79, 185, 293, 336, 424, 508, 583, 653, 675, 758, 833, 878, 953, 1012, 1101, 1125, 1128, 1142, 1210, 1242, 1327, 1399, 1565, 1697, 1759, 2043, 2070, 2151, 2269, 2286], 'favoritesGet': [23], 'permissionsTrack': [24], 'citations': [25], 'ShareShare': [26], 'onFacebookTwitterLinkedInWeChat': [27], 'Previous': [28], 'Back': [29], 'Top': [31], 'Next': [32], 'Download': [33], 'FiguresReferencesRelatedInformation': [35], 'Cited': [36], 'BySarcomere': [37], 'length': [38, 1788, 1885, 2072, 2315, 2620], 'affects': [39], 'Ca2+': [40, 274, 365, 629, 1543, 1652], 'sensitivity': [41, 2386], 'of': [42, 54, 64, 82, 97, 108, 127, 141, 145, 199, 205, 207, 216, 284, 299, 311, 327, 349, 363, 376, 384, 408, 415, 482, 532, 557, 578, 586, 593, 620, 636, 644, 664, 699, 730, 746, 783, 796, 811, 826, 866, 873, 889, 895, 910, 921, 938, 955, 966, 977, 989, 1018, 1057, 1166, 1186, 1220, 1229, 1270, 1313, 1342, 1349, 1377, 1385, 1407, 1430, 1479, 1497, 1510, 1542, 1562, 1589, 1628, 1669, 1717, 1725, 1751, 1756, 1770, 1787, 1795, 1816, 1825, 1852, 1869, 1873, 1897, 1933, 1943, 1957, 1984, 2003, 2018, 2054, 2082, 2088, 2094, 2099, 2110, 2123, 2127, 2147, 2165, 2175, 2184, 2197, 2201, 2210, 2214, 2227, 2260, 2264, 2283, 2291, 2304, 2313, 2320, 2324, 2340, 2350, 2362, 2377, 2391, 2403, 2409, 2412, 2419, 2422, 2431, 2438, 2470, 2487, 2502, 2519, 2563, 2568, 2573, 2589, 2595, 2601, 2607, 2615, 2618, 2653, 2701, 2711, 2718, 2725, 2732, 2758, 2778], 'contraction': [43, 1194, 1563], 'ischemic': [45, 542, 567, 660], 'but': [46], 'not': [47, 947], 'non-ischemic': [48], 'myocardium12': [49], 'January': [50, 153, 190, 279, 430, 725], '2023': [51], '|': [52, 70, 94, 134, 155, 172, 192, 224, 242, 255, 281, 303, 374, 400, 432, 447, 479, 696, 727, 780, 864, 883, 904, 932, 974, 1054, 1113, 1180, 1217, 1267, 1339, 1374, 1476, 1549, 1586, 1621, 1675, 1813, 1849, 1894, 1930], 'Journal': [53, 96, 107, 283, 481, 698, 729, 782, 865, 888, 909, 937, 976, 1056, 1185, 1219, 1269, 1341, 1376, 1478, 1509, 1588, 1815, 1851, 1896, 1932, 2081, 2174, 2411, 2437, 2710, 2731], 'General': [55, 2451], 'Physiology,': [56, 98, 109, 137, 227, 435, 486, 703, 734, 787, 868, 890, 911, 939, 978, 1061, 1187, 1221, 1274, 1343, 1483, 1593, 1622, 1820, 1856, 1898, 1937, 2083, 2439, 2712, 2733], 'Vol.': [57, 75, 99, 110, 138, 158, 178, 195, 211, 228, 245, 258, 287, 307, 325, 347, 361, 379, 402, 418, 436, 450, 487, 522, 547, 574, 602, 616, 641, 662, 704, 735, 788, 806, 869, 891, 912, 940, 958, 979, 1062, 1071, 1091, 1116, 1135, 1162, 1188, 1198, 1222, 1234, 1275, 1287, 1309, 1344, 1360, 1381, 1403, 1417, 1438, 1484, 1512, 1524, 1553, 1594, 1623, 1639, 1657, 1679, 1701, 1721, 1746, 1766, 1783, 1821, 1857, 1875, 1899, 1938, 1952, 1968, 1999, 2014, 2029, 2046, 2061, 2084, 2106, 2135, 2157, 2180, 2203, 2220, 2254, 2278, 2326, 2357, 2372, 2397, 2415, 2440, 2465, 2482, 2498, 2514, 2531, 2550, 2559, 2581, 2610, 2625, 2641, 2655, 2675, 2693, 2713, 2734, 2751, 2765], '155,': [58], 'No.': [59, 101, 112, 160, 180, 197, 247, 260, 289, 309, 381, 404, 420, 452, 489, 524, 549, 576, 604, 618, 706, 737, 790, 808, 871, 893, 914, 942, 960, 981, 1064, 1073, 1093, 1118, 1137, 1164, 1190, 1200, 1224, 1236, 1277, 1289, 1311, 1346, 1362, 1383, 1405, 1419, 1440, 1486, 1514, 1526, 1555, 1596, 1625, 1641, 1659, 1681, 1703, 1723, 1748, 1768, 1785, 1823, 1859, 1901, 1940, 1954, 1970, 2001, 2016, 2031, 2048, 2063, 2086, 2108, 2137, 2159, 2182, 2205, 2222, 2256, 2280, 2328, 2359, 2374, 2399, 2417, 2442, 2467, 2484, 2500, 2516, 2533, 2552, 2561, 2583, 2612, 2627, 2643, 2657, 2677, 2695, 2715, 2736, 2753, 2767], '3Electrophysiological': [60], 'Molecular': [62, 323, 345, 359, 600, 637, 804, 1133, 1160, 1436, 1533, 1744, 1764], 'Mechanisms': [63], 'Sinoatrial': [65], 'Node': [66], 'Mechanosensitivity9': [67], 'August': [68, 1337], '2021': [69], 'Frontiers': [71, 135, 225, 433], 'Cardiovascular': [73, 243, 256, 416, 1114, 2178], 'Medicine,': [74, 1656, 2414], '8CaMKII': [76], 'activity': [77, 1429], 'contributes': [78], 'homeometric': [80], 'autoregulation': [81], 'the': [83, 89, 125, 149, 214, 297, 315, 333, 354, 390, 395, 442, 455, 526, 533, 538, 541, 551, 558, 563, 566, 590, 632, 650, 657, 668, 747, 829, 918, 925, 967, 994, 1009, 1019, 1067, 1102, 1122, 1206, 1240, 1323, 1334, 1350, 1395, 1413, 1427, 1445, 1494, 1539, 1559, 1629, 1663, 1670, 1685, 1693, 1706, 1754, 1796, 1866, 1870, 1948, 1961, 1965, 2055, 2066, 2142, 2169, 2198, 2239, 2251, 2270, 2287, 2305, 2321, 2330, 2336, 2366, 2404, 2420, 2428, 2495, 2527, 2586, 2590, 2598, 2602, 2616, 2633, 2744, 2779], 'heart:': [84, 926, 1123, 1151], 'A': [85], 'novel': [86, 232], 'mechanism': [87, 235, 2272, 2430], 'for': [88, 124, 163, 607, 1684, 1739, 1865, 2145, 2647], 'Anrep': [90, 708, 817, 962], 'effect14': [91], 'June': [92, 170, 477, 1265], '2020': [93, 133, 154], 'The': [95, 282, 530, 555, 975, 1218, 1340, 1895, 2262], '598,': [100, 111], '15Mechano‐electric': [102], 'mechano‐chemo‐transduction': [104], 'cardiomyocytesThe': [106], '7Stretch-Induced': [113], 'Biased': [114], 'Signaling': [115], 'Angiotensin': [117], 'II': [118, 265, 646, 1095], 'Type': [119], '1': [120, 267, 2802, 2808], 'Apelin': [122], 'Receptors': [123], 'Mediation': [126], 'Cardiac': [128, 1013, 1521, 1718, 2292, 2301, 2445, 2448, 2454], 'Contractility': [129, 1408], 'Hypertrophy13': [131], 'March': [132, 749, 902, 1811, 1847], '11Stretch': [139], 'modulation': [140], 'cardiac': [142, 200, 238, 316, 364, 608, 899, 1431, 1452, 1757, 1797, 2148, 2195, 2703, 2727], 'contractility:': [143], 'importance': [144], 'myocyte': [146, 896], 'calcium': [147, 201, 351, 1170, 1425, 1752, 1831, 2318, 2351, 2381, 2385], 'during': [148, 631, 1992], 'slow': [150, 182, 270, 317, 391, 527, 552, 633, 672, 830, 950, 1104, 1139, 1207, 1324, 1560, 1867, 2067], 'force': [151, 183, 318, 392, 528, 553, 634, 673, 792, 831, 1105, 1140, 1167, 1208, 1878, 2068], 'response14': [152], 'Biophysical': [156, 448], 'Reviews,': [157, 449], '12,': [159], '1Magnetics-Based': [161], 'Approach': [162], 'Fine-Tuning': [164], 'Afterload': [165, 1411], 'Engineered': [167], 'Heart': [168, 220, 305, 505, 822, 1068, 1089, 2276, 2780], 'Tissues11': [169], '2019': [171, 191], 'ACS': [173], 'Biomaterials': [174], 'Science': [175, 613], '&': [176, 1232, 2792], 'Engineering,': [177], '5,': [179, 2107, 2398], '7The': [181, 382, 961], 'response': [184, 335, 393, 652, 674, 757, 793, 832, 877, 952, 1106, 1141, 1209, 1241, 1326, 1755], 'stretch:': [186, 337, 1282], 'Controversy': [187], 'contradictions25': [189], 'Acta': [193, 1676], 'Physiologica,': [194], '226,': [196], '1Regulation': [198], 'by': [202, 369, 491, 516, 1083, 1172, 1501, 1601, 1732, 2309, 2796], 'mechanotransduction:': [203], 'Role': [204, 742, 988, 1683, 2774], 'mitochondriaArchives': [206], 'Biochemistry': [208], 'Biophysics,': [210, 401], '659Calcium': [212], 'Pathophysiology': [215], 'Atrial': [217, 1001, 1780], 'Fibrillation': [218], 'Failure4': [221], 'October': [222, 778, 997, 1005, 1015, 1215, 1474], '2018': [223, 241, 254], '9Stretch-induced': [229], 'compliance:': [230], 'a': [231, 927, 949, 1491, 2071], 'adaptive': [233], 'biological': [234], 'following': [236, 1280, 2246], 'acute': [237, 654, 2247], 'load1': [239], 'February': [240, 253, 881], 'Research,': [244, 257, 378, 521, 1070, 1115, 1359, 1402, 1523, 1638, 1700, 1720, 1782, 1951, 2219, 2253, 2356, 2371, 2464, 2497, 2513, 2530, 2558, 2580, 2624, 2640, 2750, 2764], '114,': [246, 259], '5Can': [248], 'stress': [249], 'make': [250], 'you': [251], 'relax?9': [252], '5TRPC3': [261], 'participates': [262], 'angiotensin': [264, 645], 'type': [266], 'receptor-dependent': [268], 'stress-induced': [269], 'increase': [271, 751, 1451, 2241], 'intracellular': [273, 1424], 'concentration': [275, 588, 1883, 2382], 'mouse': [277], 'cardiomyocytes19': [278], '2017': [280, 302, 373], 'Physiological': [285, 2459, 2798], 'Sciences,': [286], '68,': [288, 419], '2The': [290, 707, 2281, 2517, 2553], 'adaption': [292], 'preload': [294, 1173], 'depends': [295], 'on': [296, 314, 389, 439, 627, 898, 1022, 1066, 1394, 1828, 1909, 2091, 2096, 2187, 2192, 2353, 2427, 2453, 2477, 2523, 2570, 2597, 2621, 2632, 2721], 'amount': [298], 'afterload19': [300], 'April': [301, 972, 1619], 'ESC': [304], 'Failure,': [306, 1090], '4,': [308], '4Impact': [310], 'titin': [312], 'strain': [313, 897, 923], 'responseProgress': [319], 'Biophysics': [321, 343, 357, 598, 802, 1131, 1158, 1434, 1742, 1762], 'Biology,': [324, 346, 360, 601, 805, 957, 1134, 1161, 1437, 1552, 1745, 1765], '130Role': [326], 'TRPC3': [328], 'TRPC6': [330], 'channels': [331, 368, 1120, 1321, 1727], 'Linking': [338], 'physiology': [339], 'pathophysiologyProgress': [341], '130Mechanosensitivity': [348], 'microdomain': [350], 'signalling': [352], 'heartProgress': [355], '130Regulation': [362], 'ion': [367, 610], 'shear': [370], 'mechanotransduction12': [371], 'July': [372, 694, 1111], 'Archives': [375], 'Pharmacal': [377], '40,': [380, 2582, 2626, 2642], 'effects': [383, 643, 1021, 1908, 2594], 'afterload': [385], 'stimulation': [387], 'delay': [388], 'heterogeneous': [396, 799], 'myocardium13': [397], 'December': [398, 824, 1178, 1673, 1928], '2016': [399, 431], '61,': [403], '5Positive': [405], 'Inotropic': [406], 'Effect': [407], 'Prostaglandin': [409], 'F2α': [410], 'Rat': [412, 1520, 1779], 'Ventricular': [413, 1003, 2008, 2760], 'TrabeculaeJournal': [414], 'Pharmacology,': [417], '1Acute': [421], 'Myocardial': [422, 815, 819, 986, 1400, 1602, 1636, 1698, 2092], 'Response': [423, 1077, 1354, 1398, 1696, 1963], 'Stretch:': [425, 816], 'What': [426], 'We': [427], "(don't)": [428], 'Know5': [429], '6Historical': [437], 'perspective': [438], 'heart': [440, 1645, 1994, 2306], 'function:': [441], 'Frank–Starling': [443], 'Law19': [444], 'November': [445, 1052, 1372], '2015': [446, 478], '7,': [451, 2483], '4Mechanosignaling': [453], 'vasculature:': [456], 'emerging': [457], 'concepts': [458], 'sensing,': [460], 'transduction': [461, 920], 'physiological': [463, 2052], 'responsesShampa': [464], 'Chatterjee,': [465], 'Keigi': [466], 'Fujiwara,': [467], 'Néstor': [468, 687, 715, 1250, 1610], 'Gustavo': [469], 'Pérez,': [470, 689, 717, 837, 1252, 1612], 'Masuko': [471], 'Ushio-Fukai,': [472], 'Aron': [474], 'B.': [475, 839], 'Fisher15': [476], 'American': [480, 697, 728, 781, 1055, 1268, 1477, 1508, 1587, 1814, 1850, 1931, 2199, 2322, 2797], 'Physiology-Heart': [483, 700, 731, 784, 1058, 1271, 1480, 1590, 1817, 1853, 1934], 'Circulatory': [485, 702, 733, 786, 1060, 1273, 1482, 1592, 1819, 1855, 1936], '308,': [488], '12Letter': [490], 'Villa': [492], 'Abrille': [493], 'et': [494], 'al': [495], 'Regarding': [496], 'Article,': [497], '"Hyperactive': [498], 'Adverse': [499], 'Mechanical': [500], 'Stress': [501], 'Responses': [502], 'Dystrophic': [504], 'Are': [506], 'Coupled': [507], 'Transient': [509, 1713], 'Receptor': [510], 'Potential': [511], 'Canonical': [512], '6': [513], 'Blocked': [515], 'cGMP-Protein': [517], 'Kinase': [518], 'G': [519], 'Modulation"Circulation': [520], '116,': [523, 2279], '1Revisiting': [525], 'response:': [529, 554], 'role': [531, 556, 1750], 'PKG': [534, 559], 'signaling': [535, 560, 647, 1279], 'pathway': [536, 561, 648], 'normal': [539, 564, 658, 1980], 'heartRevista': [543, 568], 'Portuguesa': [544, 569], 'de': [545, 570, 1192, 1259, 1617], 'Cardiologia,': [546], '33,': [548, 575], '9Revisiting': [550], 'Cardiologia': [571], '(English': [572], 'Edition),': [573], '9Use': [577], 'liquid': [579], 'chromatography-mass': [580], 'spectrometry': [581], '(LC-MS)': [582], 'detect': [584], 'substances': [585], 'nanomolar': [587], 'coronary': [591], 'effluent': [592], 'isolated': [594, 1175, 1888, 2024, 2075, 2100, 2432], 'perfused': [595, 1026], 'heartsProgress': [596], '115,': [603], '2-3Molecular': [605], 'candidates': [606], 'stretch-activated': [609, 1320], 'channelsGlobal': [611], 'Cardiology': [612], 'Practice,': [615], '2014,': [617], '2Effect': [619], 'SR': [621], 'load': [622, 2475], 'pH': [624], 'regulatory': [625], 'mechanisms': [626, 875, 1537, 1738, 1864], 'stretch-dependent': [628], 'entry': [630], 'responseJournal': [635, 1872], 'Cellular': [639, 1531], 'Cardiology,': [640, 1511, 1998, 2060, 2156, 2202, 2325, 2549, 2674, 2692], '63The': [642], 'systolic': [651, 2112], 'stretch': [655, 1143, 1211, 1328, 1540, 1827], 'myocardiumPeptides,': [661], '47Inhibition': [663], 'carbonic': [665], 'anhydrase': [666], 'prevents': [667], 'Na+/H+': [669], 'exchanger': [670], '1-dependent': [671], 'rat': [676, 1335, 1644, 1671, 1889, 2346], 'stretchLorena': [678], 'A.': [679, 772, 1254, 1922], 'Vargas*,': [680], 'Romina': [681], 'G.': [682, 688, 716, 836, 1251, 1611, 1926], 'Díaz*,': [683], 'Erik': [684], 'R.': [685, 1457], 'Swenson,': [686], 'Bernardo': [691, 852], 'V.': [692, 853], 'Álvarez15': [693], '2013': [695, 726], '305,': [705], 'effect:': [709], '100': [710], 'years': [711], 'laterHoracio': [712], 'E.': [713, 860, 1263, 1608], 'Cingolani,': [714, 720, 848, 1609], 'Oscar': [718], 'H.': [719, 767, 1460], 'Irene': [722, 855], 'L.': [723, 850, 856, 1245], 'Ennis15': [724], '304,': [736], '2Mechano-Electric': [738], 'Interactions': [739, 2771], 'Their': [741, 2741, 2773], 'Electrical': [744, 2776], 'Function': [745, 2009, 2226, 2777], 'Heart16': [748], '2013Intrinsic': [750], 'lymphangion': [753], 'muscle': [754, 1332, 1449, 1758, 2051, 2314, 2389, 2619, 2648, 2704], 'contractility': [755, 797, 2167, 2245], 'elevated': [759], 'afterloadMichael': [760], 'J.': [761, 1029], 'Davis,': [762], 'Joshua': [763], 'P.': [764, 1461], 'Scallan,': [765], 'John': [766], 'Wolpers,': [768], 'Mariappan': [769], 'Muthuchamy,': [770], 'Anatoliy': [771], 'Gashev,': [773], 'David': [775], 'C.': [776, 842, 845, 1257, 1615], 'Zawieja1': [777], '2012': [779], '303,': [789], '7Slow': [791], 'auto-regulation': [795], 'myocardiumProgress': [800], '110,': [807], '2-3Early': [809], 'Activation': [810], 'Intracellular': [812], 'Signals': [813, 984], 'after': [814, 1647, 1884, 2011], 'Effect,': [818], 'Hypertrophy': [820], 'Failure5': [823], '2012Silencing': [825], 'NHE-1': [827], 'blunts': [828], 'stretchNéstor': [835], 'Mariela': [838], 'Nolly,': [840], 'Mirian': [841], 'Roldan,': [843], 'María': [844, 1256, 1614], 'Villa-Abrille,': [846], 'Eugenio': [847], 'Enrique': [849], 'Portiansky,': [851], 'Álvarez,': [854], 'Ennis,': [857, 1246], 'Horacio': [859, 1262], 'Cingolani1': [861, 1264], 'September': [862, 1547, 1892], '2011': [863, 882, 903, 931, 1373], 'Applied': [867], '111,': [870, 1235], '3Role': [872], 'autocrine/paracrine': [874, 1284], 'strain8': [880], 'Pflügers': [884, 905, 933, 1181], 'Archiv': [885, 906, 934, 1182, 2079, 2435, 2708, 2729], '-': [886, 907, 935, 1183, 1196], 'European': [887, 908, 936, 1184, 2080, 2436, 2709, 2730], '462,': [892, 913, 941], '1Impact': [894], 'myofilament': [900, 2317], 'activation16': [901], '1The': [915, 1527, 1749, 2768], 'cytoskeleton': [916], 'cellular': [919], 'mechanical': [922, 1733, 2097], 'special': [928], 'issue19': [929], '1Rainbow': [943], 'trout': [944], 'myocardium': [945, 1148], 'does': [946], 'exhibit': [948], 'inotropic': [951, 1325], 'stretchJournal': [954], 'Experimental': [956, 1655, 2608], '214,': [959], 'effect': [963, 2631, 2717], 'requires': [964], 'transactivation': [965], 'epidermal': [968], 'growth': [969], 'factor': [970], 'receptor30': [971], '2010': [973], '588,': [980], '9Early': [982], 'Hypertrophic': [983], 'After': [985, 1635], 'Stretch.': [987], 'Reactive': [990], 'Oxygen': [991], 'Species': [992], 'Sodium/Hydrogen': [995], 'Exchanger15': [996], '2009Stretch-Induced': [998], 'Inotropy': [999], 'Myocardium15': [1004], '2009Stretch-Activated': [1006], 'Channels': [1007], 'Heart:': [1010], 'Contribution': [1011, 2282], 'Performance15': [1014], '2009Pharmacological': [1016], 'modifications': [1017], 'stretch-induced': [1020, 1103, 1421, 1664], 'ventricular': [1023, 1147, 1568, 1826, 1890, 1911, 1989, 2216, 2244, 2267, 2406, 2471, 2478, 2521, 2554, 2638], 'fibrillation': [1024], 'rabbit': [1027, 1176, 2076, 2101], 'heartsFrancisco': [1028], 'Chorro,': [1030], 'Isabel': [1031], 'Trapero,': [1032], 'Luis': [1033, 1037, 1050], 'Such-Miquel,': [1034], 'Francisca': [1035], 'Pelechano,': [1036], 'Mainar,': [1038], 'Joaquín': [1039], 'Cánoves,': [1040], 'Álvaro': [1041], 'Tormos,': [1042], 'Antonio': [1043], 'Alberola,': [1044], 'Leif': [1045], 'Hove-Madsen,': [1046], 'Juan': [1047], 'Cinca,': [1048], 'Such1': [1051], '2009': [1053], '297,': [1063], '5Pulling': [1065], 'StringsCirculation': [1069], '104,': [1072], '6Reduced': [1074], 'Stretch-Induced': [1075, 1771], 'Force': [1076, 1353, 1397, 1695, 1709], 'Failing': [1079, 1356], 'Human': [1080, 1357], 'Myocardium': [1081], 'Caused': [1082], 'Impaired': [1084], 'Na': [1085, 1314, 1386, 1630, 1687], '+': [1086, 1315, 1317, 1387, 1631, 1688, 1690], '-Contraction': [1087], 'CouplingCirculation:': [1088], '2,': [1092], '1Angiotensin': [1094], 'myosin': [1097], 'light-chain': [1098], 'phosphorylation': [1099, 2274], 'contribute': [1100], 'human': [1108, 1150, 1981], 'atrial': [1109, 1145], 'myocardium2': [1110], '2008': [1112], '79,': [1117], '4Stretch-activated': [1119], 'Contributions': [1124], 'length-dependence': [1126], 'cardiomyopathyProgress': [1129], '97,': [1136, 1163, 2181], '2-3The': [1138], 'from': [1149, 1169, 1333, 1505, 2119, 2345, 2782], 'Functional': [1152], 'relevance': [1153], 'subcellular': [1155], 'mechanismsProgress': [1156], '2-3Dissociation': [1165], 'decline': [1168, 1171], 'myocardium4': [1177], '2007': [1179, 1216], '456,': [1189], '2Physiologie': [1191], 'la': [1193], 'cardiaqueEMC': [1195], 'Cardiologie,': [1197], '3,': [1199, 1554], '4Mitochondrial': [1201], 'reactive': [1202], 'oxygen': [1203], 'species': [1204], 'activate': [1205], 'feline': [1213], 'myocardium31': [1214], '584,': [1223], '3Cardiovascular': [1225], 'endothelins:': [1226], 'Essential': [1227], 'regulators': [1228], 'cardiovascular': [1230], 'homeostasisPharmacology': [1231], 'Therapeutics,': [1233], '2Endothelin': [1237], 'isoforms': [1238], 'stretchIrene': [1244], 'Carolina': [1247], 'D.': [1248, 1809], 'Garciarena,': [1249], 'Raúl': [1253], 'Dulce,': [1255], 'Camilión': [1258, 1616], 'Hurtado,': [1260], '2005': [1266], '288,': [1276], '6Intracellular': [1278], 'an': [1283, 1502, 1792, 2310], 'loopRegulatory': [1285], 'Peptides,': [1286], '128,': [1288], '3Mechanisch': [1290], 'induzierte': [1291], 'Dissoziation': [1292], 'von': [1293], 'Kalzium': [1294], 'vom': [1295], 'kontraktilen': [1296], 'Apparat': [1297], 'elektrisch': [1298], 'stimulierter,': [1299], 'intakter,': [1300], 'menschlicher,': [1301], 'atrialer': [1302], 'TrabekelZeitschrift': [1303], 'f�r': [1304], 'Herz-,': [1305], 'Thorax-': [1306], 'und': [1307, 2545, 2659, 2669, 2679, 2684], 'Gef��chirurgie,': [1308], '18,': [1310], '5Activation': [1312], '-H': [1316], 'exchange': [1318], 'underlies': [1322], 'myocytes': [1330], 'heart10': [1336], '2004': [1338, 1893], '559,': [1345], '1Functional': [1347], 'Relevance': [1348], 'Stretch-Dependent': [1351], 'Slow': [1352, 1396, 1694], 'MyocardiumCirculation': [1358], '94,': [1361], '10MODELING': [1363], 'OF': [1364], 'PROTEIN': [1365], 'INTERACTIONS': [1366], 'INVOLVED': [1367], 'IN': [1368], 'CARDIAC': [1369], 'TENSION': [1370], 'DEVELOPMENT20': [1371], 'International': [1375], 'Bifurcation': [1378], 'Chaos,': [1380], '13,': [1382, 2204], '12Influence': [1384], '-Independent': [1388], 'Cl': [1389], '−': [1390], '-HCO': [1391], '3−': [1392], 'Exchange': [1393, 1634], 'StretchCirculation': [1401, 1637, 1699], '93,': [1404], '11Enhancement': [1406], 'With': [1409], 'Sustained': [1410], 'Intact': [1414], 'Murine': [1415], 'HeartCirculation,': [1416, 1967], '107,': [1418], '23Do': [1420], 'modify': [1426], 'electrical': [1428], 'muscle?Progress': [1432], '82,': [1439], '1-3Stretch-Elicited': [1441], 'Autocrine/Paracrine': [1442, 1598], 'Mechanism': [1443, 1599], 'HeartCoronary': [1446], 'perfusion': [1447], 'lengthening': [1450], 'contraction:': [1453], 'different': [1454], 'stretch-triggered': [1455], 'mechanismsRegis': [1456], 'Lamberts,': [1458], 'Mattie': [1459], 'van': [1462], 'Rijen,': [1463], 'Pieter': [1464], 'Sipkema,': [1465], 'Paul': [1466], 'Fransen,': [1467], 'Stanislas': [1468], 'U.': [1469], 'Sys,': [1470], 'Nico': [1472], 'Westerhof1': [1473], '2002': [1475], '283,': [1485], '4William': [1487], 'Watts': [1488], 'MD:': [1490], 'conversation': [1492], 'with': [1493, 2235, 2649], 'editor**This': [1495], 'series': [1496], 'interviews': [1498], 'is': [1499, 2307], 'underwritten': [1500], 'unrestricted': [1503], 'grant': [1504], 'Bristol-Myers': [1506], 'Squibb.The': [1507], '89,': [1513], '9Myofilament': [1515], 'Calcium': [1516, 2294], 'Sensitivity': [1517], 'Skinned': [1519], 'TrabeculaeCirculation': [1522], '90,': [1525], 'Frank': [1528], '-Starling': [1529], 'Relationship:': [1530], 'MechanismsEndogenous': [1534], 'nitric': [1535], 'oxide': [1536], 'mediate': [1538], 'dependence': [1541, 2361, 2376], 'release': [1544], 'cardiomyocytes6': [1546], '2001': [1548, 1585, 1620, 1674], 'Nature': [1550], 'Cell': [1551, 2395], '10Heart': [1556], 'rate': [1557], 'modulates': [1558, 1662], 'enhancement': [1561], 'due': [1564], 'sudden': [1566, 2719], 'left': [1567, 1910, 1988, 2172, 2243, 2266, 2405, 2433, 2507, 2520, 2575], 'dilationPaulo': [1569], 'José': [1570], 'Ferreira': [1571], 'Tucci,': [1572], 'Neif': [1573], 'Murad,': [1574], 'Clever': [1575], 'Land': [1576], 'Rossi,': [1577], 'Roberto': [1578], 'Janzon': [1579], 'Nogueira,': [1580], 'Orlando': [1582], 'Santana1': [1583], '280,': [1595], '5An': [1597], 'Triggered': [1600], 'Stretch': [1603, 1716], 'Induces': [1604], 'Changes': [1605, 1772, 2298], 'ContractilityHoracio': [1607], 'Hurtado1': [1618], '16,': [1624], '2Reverse': [1626], 'Mode': [1627], '-Ca': [1632], '2+': [1633, 1712, 1775, 1882], '88,': [1640, 2047, 2062], '4Isolated': [1642], 'working': [1643], 'adaptation': [1646], 'abrupt': [1648], 'extracellular': [1651], 'concentrationResearch': [1653], 'In': [1654, 2228], '200,': [1658], '2Intracellular': [1660], 'acidosis': [1661], 'E-C': [1667], 'coupling': [1668], 'atrium24': [1672], 'Physiologica': [1677], 'Scandinavica,': [1678], '167,': [1680], '3A': [1682, 2613, 2644], 'Sarcolemmal': [1686], '/H': [1689], 'Exchanger': [1691], '85,': [1702, 1722, 2015], '8Mechanisms': [1704], 'Underlying': [1705], 'Increase': [1707], 'Ca': [1711, 1881], 'That': [1714], 'Follow': [1715], 'MuscleCirculation': [1719], '8Modulation': [1724], 'ions': [1726], 'membrane': [1729], 'receptors': [1730], 'activities': [1731], 'interventions': [1734], 'cardiomyocytes:': [1736], 'possible': [1737], 'mechanosensitivityProgress': [1740], '71,': [1747, 1767, 2676], 'stretchProgress': [1760], '1Mechanisms': [1769], '[Ca': [1774], ']': [1776], 'i': [1777], 'MyocytesCirculation': [1781], '83,': [1784], '11Mechanisms': [1786], 'history-dependent': [1789], 'tension': [1790], 'ionic': [1793], 'model': [1794], 'myocyteWolfgang': [1798], 'F.': [1799], 'Bluhm,': [1800], 'Wilbur': [1801], 'Y.': [1802], 'W.': [1803], 'Lew,': [1804], 'Alan': [1805], 'Garfinkel,': [1806], 'Andrew': [1808], 'McCulloch1': [1810], '1998': [1812, 1848], '274,': [1822, 1858], '3Effect': [1824], 'strength,': [1830], 'transient,': [1832], 'cAMP': [1834], 'intact': [1836, 1985, 2341], 'canine': [1837, 2171, 2215, 2506, 2574], 'heartsKoji': [1838], 'Todaka,': [1839], 'Kazuhide': [1840], 'Ogino,': [1841], 'Anguo': [1842], 'Gu,': [1843], 'Daniel': [1845], 'Burkhoff1': [1846], '3Molekulare': [1860], 'Grundlagen': [1861], 'der': [1862, 2662], 'HerzinsuffizienzCellular': [1863], 'phase': [1868], 'frank—starling': [1871], 'Electrocardiology,': [1874], '31Changes': [1876], 'cytosolic': [1880], 'trabeculae22': [1891], '506,': [1900], '2Ejection': [1902], 'has': [1903], 'both': [1904], 'positive': [1905], 'negative': [1907], 'isovolumic': [1912, 2020, 2367], 'relaxationDavid': [1913], 'S.': [1914], 'Berger,': [1915], 'Katherine': [1916], 'Vlasica,': [1917], 'Christopher': [1918], 'M.': [1919], 'Quick,': [1920], 'Kimberly': [1921], 'Robinson,': [1923], 'Sanjeev': [1925], 'Shroff1': [1927], '1997': [1929], '273,': [1939], '6Mechanical': [1941], 'Transduction': [1942], 'Nitric': [1944, 1958], 'Oxide': [1945, 1959], 'Synthesis': [1946], 'Beating': [1949], 'HeartCirculation': [1950], '81,': [1953], '3Basal': [1955], 'Release': [1956], 'Augments': [1960], 'Frank-Starling': [1962, 2271], 'Isolated': [1966], '96,': [1969], '4Myocardial': [1971], 'length-force': [1972, 2338], 'relationship': [1973, 2263], 'end': [1975], 'stage': [1976], 'dilated': [1977], 'cardiomyopathy': [1978], 'myocardium:': [1982], 'analysis': [1983], 'skinned': [1987, 2343], 'trabeculae': [1990, 2344], 'obtained': [1991], '11': [1993], 'transplantationsBasic': [1995], 'Research': [1996, 2058, 2154, 2393, 2547, 2672, 2690], '92,': [2000], '4Recovery': [2002], 'Systolic': [2004], 'Diastolic': [2006], 'Left': [2007, 2230, 2748, 2759], 'Early': [2010], 'Cardiopulmonary': [2012], 'BypassAnesthesiology,': [2013], '5Characteristics': [2017], 'left-ventricular': [2019, 2111], 'pressure': [2021, 2504, 2572], 'waves': [2022], 'dog': [2025, 2369, 2528], 'heartsHeart': [2026], 'Vessels,': [2028, 2134], '9,': [2030, 2416], '3Postextrasystolic': [2032], 'potentiation.': [2033], 'Do': [2034], 'we': [2035], 'really': [2036], 'know': [2037], 'what': [2038], 'it': [2039], 'means': [2040], 'how': [2042], 'use': [2044], 'it?Circulation,': [2045], '6Geometric': [2049], 'factors': [2053], 'frank-starling': [2056], 'mechanismBasic': [2057], '1Isoprenaline': [2064], 'reverses': [2065], 'responses': [2069], 'change': [2073], 'papillary': [2077], 'musclePfl�gers': [2078, 2728], '421,': [2085], '5Effects': [2087, 2562], 'Endocardial': [2089], 'Damage': [2090], 'ContractionEffect': [2093], 'propionyl-L-carnitine': [2095], 'function': [2098], 'heartCardiovascular': [2102], 'Drugs': [2103], 'Therapy,': [2105], '1Estimation': [2109], 'performance': [2113], 'its': [2115, 2630], 'determinants': [2116, 2213], 'man': [2118], 'pressures': [2120], 'dimensions': [2122], 'one': [2124], 'beat:': [2125], 'Effects': [2126], 'aortic': [2128], 'valve': [2129], 'stenosis': [2130], 'replacementHeart': [2132], '6,': [2136], '1Ventricular': [2138], 'pressure-volume': [2139, 2555], 'relations': [2140, 2339, 2700, 2724], 'as': [2141, 2212], 'primary': [2143], 'basis': [2144, 2460], 'evaluation': [2146], 'mechanics': [2149], 'Return': [2150], "Frank's": [2152], 'diagramBasic': [2153], '84,': [2158], '3Preloading': [2160], 'history': [2161, 2209], 'influences': [2162], 'pressure-volume-derived': [2163], 'indices': [2164], 'ejecting': [2170], 'ventricleThe': [2173], 'Thoracic': [2176], 'Surgery,': [2179], '4Influence': [2183], 'loading': [2185, 2249], 'patterns': [2186], 'peak': [2188], 'length-tension': [2189, 2634], 'relation': [2190, 2332, 2635], 'relaxation': [2193], 'muscleJournal': [2196], 'College': [2200, 2323], '2Long-term': [2206], 'versus': [2207], 'intrabeat': [2208], 'ejection': [2211, 2569], 'end-systolic': [2217, 2571], 'pressure.Circulation': [2218], '64,': [2221], '2Contractility': [2223], 'Pump': [2225], 'Vivo': [2229], 'Ventricle': [2231], 'Its': [2233], 'Coupling': [2234], 'Arterial': [2236], 'Load:': [2237], 'Testing': [2238], 'AssumptionsTime-dependent': [2240], 'volume': [2248, 2268, 2426, 2511, 2565, 2578], 'dog.Circulation': [2252], '63,': [2255], '3Mechanics': [2257], 'energetics': [2259], 'overstretch:': [2261], 'altered': [2265], 'potentialAmerican': [2275], 'Journal,': [2277], 'Myofibrillar': [2284], 'Properties': [2285], 'Sarcomere': [2288], 'Length-Force': [2289], 'Relationship': [2290], 'MuscleIntracellular': [2293], 'Concentration': [2295], 'Following': [2296], 'Length': [2297], 'Mammalian': [2300], "MuscleStarling's": [2302], 'law': [2303], 'explained': [2308], 'intimate': [2311], 'interaction': [2312], 'activationJournal': [2319], '10,': [2327, 2656], '5On': [2329], 'force-length': [2331], 'myocardiumComparison': [2334], 'between': [2335], 'sarcomere': [2337], 'right': [2347], 'ventricle.': [2348, 2508, 2576], 'Influence': [2349], 'concentrations': [2352], 'these': [2354], 'relations.Circulation': [2355], '58,': [2358], '6Length': [2360], 'activation': [2363], 'studied': [2364], 'blood-perfused': [2368], 'heart.Circulation': [2370, 2529], '55,': [2373], '1Length': [2375], 'sarcoplasmic': [2380], 'myofibrillar': [2384], 'striated': [2388], 'fibresJournal': [2390], 'Muscle': [2392], 'Motility,': [2396], '3Nuclear': [2400], 'medical': [2401], 'determination': [2402], 'normalized': [2407], 'velocity': [2408, 2421, 2567], 'contractionEuropean': [2410], 'Nuclear': [2413], '5Influence': [2418], 'end-diastolic': [2425], 'starling': [2429], 'ventriclesPfl�gers': [2434], '396,': [2441], '3Relationship': [2443], 'Between': [2444], 'Work': [2446], 'Growth:': [2449], 'Some': [2450], 'Thoughts': [2452], 'HypertrophyContraction-excitation': [2455], 'feedback': [2456], 'myocardium.': [2458], 'clinical': [2462], 'relevance.Circulation': [2463], '50,': [2466], '6Separate': [2468], 'contribution': [2469], '·': [2472], 'pumping': [2473], 'impedance': [2476], 'power': [2479], 'outputMedical': [2480], 'Hypotheses,': [2481], '8Caffeine': [2485], 'reversal': [2486], 'length-dependent': [2488], 'state': [2493], 'cat.Circulation': [2496], '47,': [2499], '4Determinants': [2501], 'instantaneous': [2503], 'Time': [2509], 'specification.Circulation': [2512], '46,': [2515], 'influence': [2518, 2617], 'filling': [2522], 'postextrasystolic': [2524], 'potentiation': [2525], '44,': [2532], '5Indirekter': [2534], 'Nachweis': [2535], 'einer': [2536], 'dehnungsinduzierten': [2537], 'Ca++-Freisetzung': [2538], 'aus': [2539], 'dem': [2540], 'sarkoplasmatischen': [2541], 'Retikulum': [2542], 'glyzerinisierter': [2543], 'Skelett-': [2544], 'HerzmuskelpräparateBasic': [2546], '74,': [2551], 'diagram': [2556, 2697], 'revisited.Circulation': [2557], '43,': [2560], 'stroke': [2564], 'End-systolic': [2577], 'clamping.Circulation': [2579], '5Microtubules': [2584], '"chloride': [2587], 'cell"': [2588], 'gill': [2591], 'disruptive': [2593], 'colchicine': [2596], 'salt': [2599], 'balance': [2600], 'sea': [2603], 'water': [2604], 'adaptedMugil': [2605], 'capitoJournal': [2606], 'Zoology,': [2609], '199,': [2611], 'reexamination': [2614], 'performance.Circulation': [2623], '3Length-dependent': [2628], 'activation:': [2629], 'cat': [2637], 'muscle.Circulation': [2639], 'three-element': [2645], 'description': [2646], 'viscoelastic': [2650], 'passive': [2651], 'elementsJournal': [2652], 'Biomechanics,': [2654], '1Dehnungs-': [2658], 'entdehnungsinduzierte': [2660, 2680], 'Änderungen': [2661, 2681], 'Mechanik': [2663], 'des': [2664, 2687], 'Katzenpapillarmuskels': [2665], 'bei': [2666], 'Variation': [2667], 'physikalischer': [2668], 'chemischer': [2670], 'ParameterBasic': [2671], '4Dehnungs-': [2678], 'im': [2682], 'passiven': [2683], 'aktiven': [2685], 'Verhalten': [2686], 'isolierten': [2688], 'KatzenpapillarmuskelsBasic': [2689], '70,': [2694], '3Length-tension': [2696], 'force-velocity': [2699, 2723], 'mammalian': [2702, 2726], 'under': [2705], 'steady-state': [2706], 'conditionsPfl�gers': [2707], '355,': [2714], '4The': [2716], 'stretches': [2720], 'length-tension-and': [2722], '357,': [2735], '3-4Instantaneous': [2737], 'Pressure-Volume': [2738], 'Relationships': [2739], 'Ratio': [2742], 'Excised,': [2745], 'Supported': [2746], 'Canine': [2747], 'VentricleCirculation': [2749], '35,': [2752], '1Brief': [2754], 'Reviews': [2755], ':': [2756], 'Determination': [2757], 'Size': [2761], 'ShapeCirculation': [2763], '34,': [2766], 'Mechanosensory': [2769], 'HeartMechanoelectrical': [2770], 'More': [2781], 'this': [2783], 'issue': [2784], '>': [2785], 'Volume': [2786], '224Issue': [2787], '5May': [2788], '1973Pages': [2789], '1195-1199': [2790], 'Copyright': [2791], 'PermissionsCopyright': [2793], '©': [2794], '1973': [2795, 2804, 2810], 'Societyhttps://doi.org/10.1152/ajplegacy.1973.224.5.1195PubMed4700639History': [2799], 'Published': [2800, 2805], 'online': [2801], 'print': [2807], 'Metrics': [2811]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2417308765', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-12-07T22:43:00.145837', 'created_date': '2016-06-24'}