Chronic Intermittent Hypoxia Induces Chronic Low-Grade Neuroinflammation in the Dorsal Hippocampus of Mice

Name: Work Video:
Duration: 3 min 30 s
Description: Study Objectives:Obstructive sleep apnea (OSA) induces cognitive impairment that involves intermittent hypoxia (IH). Because OSA is recognized as a low-grade systemic inflammatory disease and only some patients develop cognitive deficits, we investigated whether IH-related brain consequences shared similar pathophysiology and required additional factors such as systemic inflammation to develop.
Emilie Sapin; Christelle Peyron; Frédéric Roche; Nadine Gay; Carole Carcenac; Marc Savasta; Patrick Lévy; Maurice Demattéis
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