Title: 3-Aminothymidine inhibits growth of cultured human T-cell acute lymphoblastoid leukemia cells.
Abstract: N3-Aminated derivatives of thymidine, deoxyuridine and deoxycytidine were synthesized and their cell growth inhibition activity was tested using two cultured human cell lines, CCRF-HSB-2 and KB. Among the compounds tested, 3-aminothymidine showed growth inhibition activity against CCRF-HSB-2 cells and inhibited DNA synthesis in these cells.
Publication Year: 1994
Publication Date: 1994-09-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 3
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