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'heterogeneity': [142, 3434], 'isoforms.': [145], 'IHC': [148, 224], 'provide': [149, 2171, 2206, 4176, 4630], 'information': [150], 'only': [151, 167, 1520, 3010], 'presence': [154], 'given': [157, 199, 1517, 1624], 'isoform,': [158, 213], 'not': [159, 1007, 1519, 1622, 2826, 2974, 3590, 4583], 'its': [160, 3488], 'proportional': [161], 'contribution.': [162], 'These': [163, 1428], 'therefore': [166, 1515], 'informative': [168, 941], 'from': [169, 782, 1619, 1666, 2888, 3679, 4725, 5273], 'qualitative': [171], 'perspective.Our': [172], 'suggested': [173], 'methodology': [174, 250, 4594, 4743], 'feasible': [176], 'labs': [179], 'perform': [181, 1628], 'and,': [182], 'importantly,': [183], 'quantitative.': [185], 'It': [186, 1557], 'allows': [187, 254], 'determination': [189, 2077, 2234, 4137], 'precise': [191], 'proportions': [192], 'all': [194], 'in': [197, 284, 288, 391, 474, 599, 682, 792, 833, 911, 1033, 1099, 1160, 1191, 1220, 1286, 1347, 1378, 1460, 1468, 1474, 1488, 1573, 1609, 1615, 1631, 1683, 1747, 1768, 1773, 1818, 1850, 1914, 1935, 1940, 1985, 2064, 2080, 2115, 2117, 2258, 2264, 2515, 2522, 2533, 2777, 2784, 2795, 2859, 2903, 2980, 2994, 3085, 3274, 3473, 3494, 3510, 3528, 3532, 3538, 3619, 3628, 3697, 3765, 3913, 4066, 4099, 4114, 4151, 4208, 4350, 4383, 4471, 4504, 4548, 4551, 4578, 4653, 4708, 4776, 4797, 4891, 5003, 5012, 5027, 5035, 5072, 5083, 5109, 5186, 5237, 5297], 'fiber.': [201], 'Additionally,': [202], 'it': [203, 253, 914, 975, 1580], 'provides': [204], 'definitive': [206], 'means': [207, 4202], 'identifying': [209, 4544], 'IIx': [211, 3078, 3267], 'something': [214], 'currently': [217], 'problematic': [218], 'respect': [220], 'techniques.': [225], 'Neonatal': [226], 'embryonic': [228], 'MHCs': [229], 'can': [230, 951, 1530, 2146, 2825, 2955, 3515, 3541], 'also': [231, 908, 1525, 1559, 4075, 4651], 'distinctly': [233], 'separated': [234], 'quantified': [236], 'electrophoresis,': [238], 'when': [239, 769, 1433, 2884, 3594, 3638, 4054, 4141, 4227], 'performed': [240], 'under': [241], 'optimized': [242], 'conditions': [243, 3467], '(6).': [244], 'Another': [245], 'specific': [246, 3443, 4190], 'advantage': [247], 'this': [249, 853, 1461, 3008, 4194, 4617, 4790, 5274], 'prediction': [257], 'functional': [259, 3617], 'properties': [260], 'muscle,': [263], 'i.e.,': [264], 'force-velocity': [265], 'relationship': [266], '(4,': [267], '5).': [268], 'has': [270, 851, 1581, 3534, 4155, 4763], 'been': [271, 1582, 3560, 4156, 4764], 'definitively': [272], 'shown': [273, 852, 3535], 'method': [277], 'sensitive': [278, 3549], 'subtle': [280], 'or': [281, 2069, 2105, 2196, 2986, 3023, 3025, 3470, 3598, 3688, 4044, 4122, 4590], 'marked': [282], 'differences': [283, 967, 998, 1665, 1767, 1934], 'isoform': [286, 315, 361, 569, 5235], 'expression': [287, 362, 570, 3540], 'response': [289, 4644], 'altered': [291, 3466], 'loading': [292], 'hormone': [294, 400, 608], 'states,': [295], 'during': [296, 511, 719, 3449, 3586, 3604, 4380, 4501], 'development,': [297], 'between': [299, 991, 1413, 1425, 2132, 2965, 4291, 4412], 'muscles': [300], 'different': [302, 2133, 3582, 3620], 'types': [304, 2967], '(2–6).': [305], 'prove': [307, 1010], 'interventions': [309, 3520], 'impact': [310], 'composition': [316], 'should': [317, 915, 943, 1514, 1655, 2223, 2270, 3693, 4074, 4130, 4148, 4175, 4786], 'determined': [319], 'approach.REFERENCES1.': [323], 'FW': [325, 533, 1052, 1239, 1696, 1863, 2286, 2548, 3037, 3226, 3708, 3856, 4307, 4428, 4812, 4906], ',': [326, 329, 352, 355, 383, 386, 417, 420, 423, 426, 429, 460, 463, 466, 469, 500, 503, 534, 537, 560, 563, 591, 594, 625, 628, 631, 634, 637, 668, 671, 674, 677, 708, 711, 1019, 1022, 1053, 1056, 1080, 1083, 1086, 1089, 1092, 1111, 1114, 1117, 1146, 1175, 1178, 1181, 1206, 1209, 1240, 1243, 1267, 1270, 1273, 1276, 1279, 1298, 1301, 1304, 1333, 1362, 1365, 1368, 1670, 1673, 1697, 1700, 1724, 1727, 1763, 1795, 1798, 1801, 1804, 1837, 1840, 1864, 1867, 1891, 1894, 1930, 1962, 1965, 1968, 1971, 2287, 2290, 2314, 2317, 2320, 2323, 2326, 2329, 2332, 2335, 2338, 2341, 2344, 2377, 2380, 2383, 2386, 2389, 2423, 2426, 2429, 2432, 2435, 2438, 2441, 2444, 2447, 2450, 2453, 2456, 2483, 2486, 2489, 2492, 2495, 2498, 2501, 2504, 2507, 2510, 2549, 2552, 2576, 2579, 2582, 2585, 2588, 2591, 2594, 2597, 2600, 2603, 2606, 2639, 2642, 2645, 2648, 2651, 2685, 2688, 2691, 2694, 2697, 2700, 2703, 2706, 2709, 2712, 2715, 2718, 2745, 2748, 2751, 2754, 2757, 2760, 2763, 2766, 2769, 2772, 3038, 3041, 3065, 3068, 3071, 3074, 3108, 3111, 3141, 3145, 3148, 3151, 3185, 3188, 3191, 3194, 3227, 3230, 3254, 3257, 3260, 3263, 3297, 3300, 3330, 3334, 3337, 3340, 3374, 3377, 3380, 3383, 3709, 3712, 3737, 3740, 3743, 3746, 3749, 3752, 3785, 3805, 3832, 3835, 3857, 3860, 3885, 3888, 3891, 3894, 3897, 3900, 3933, 3953, 3980, 3983, 4283, 4308, 4311, 4335, 4338, 4341, 4367, 4370, 4373, 4404, 4429, 4432, 4456, 4459, 4462, 4488, 4491, 4494, 4813, 4816, 4859, 4873, 4907, 4910, 4953, 4967], 'Laye': [327, 535, 1054, 1241, 1698, 1865, 2288, 2550, 3039, 3228, 3710, 3858, 4309, 4430, 4814, 4908], 'MJ': [328, 354, 385, 419, 536, 562, 593, 627, 1055, 1091, 1242, 1278, 1699, 1866, 2289, 2551, 3040, 3229, 3711, 3859, 4310, 4431, 4815, 4909], 'Spangenburg': [330, 538, 1057, 1244, 1701, 1868, 2291, 2553, 3042, 3231, 3713, 3861, 4312, 4433, 4817, 4911], 'EE.': [331, 539, 1058, 1245, 1702, 1869, 2292, 2554, 3043, 3232, 3714, 3862, 4313, 4434, 4818, 4912], 'studies.': [342, 550, 1069, 1256, 1713, 1880, 2139, 2303, 2565, 2900, 3054, 3243, 3725, 3873, 4324, 4445, 4829, 4923], 'J': [343, 370, 404, 444, 485, 518, 551, 578, 612, 652, 693, 726, 1037, 1070, 1131, 1224, 1257, 1318, 1714, 1750, 1779, 1821, 1881, 1917, 1946, 1988, 2304, 2316, 2382, 2422, 2485, 2566, 2578, 2644, 2684, 2747, 3055, 3094, 3144, 3168, 3211, 3244, 3283, 3333, 3357, 3400, 3726, 3819, 3874, 3967, 4325, 4354, 4446, 4475, 4830, 4924], 'Appl': [344, 371, 405, 552, 579, 613, 1071, 1258, 1715, 1751, 1882, 1918, 2305, 2567, 3056, 3245, 3727, 3820, 3875, 3968, 4326, 4355, 4447, 4476, 4831, 4925], 'Physiol;': [345, 553, 1072, 1259, 1716, 1883, 2306, 2568, 3057, 3246, 3728, 3876, 4327, 4448, 4832, 4926], 'doi:10.1152/japplphysiol.00125.2009.ISI': [346, 554], '|': [347, 376, 378, 410, 412, 453, 455, 492, 494, 527, 529, 555, 584, 586, 618, 620, 661, 663, 700, 702, 735, 737, 1046, 1048, 1075, 1106, 1137, 1139, 1141, 1170, 1201, 1233, 1235, 1262, 1293, 1324, 1326, 1328, 1357, 1388, 1690, 1692, 1719, 1756, 1758, 1788, 1790, 1830, 1832, 1857, 1859, 1886, 1923, 1925, 1955, 1957, 1997, 1999, 2309, 2368, 2370, 2372, 2414, 2416, 2418, 2474, 2476, 2478, 2540, 2542, 2544, 2571, 2630, 2632, 2634, 2676, 2678, 2680, 2736, 2738, 2740, 2802, 2804, 2806, 3060, 3101, 3103, 3132, 3134, 3136, 3176, 3178, 3180, 3218, 3220, 3222, 3249, 3290, 3292, 3321, 3323, 3325, 3365, 3367, 3369, 3407, 3409, 3411, 3732, 3776, 3778, 3780, 3798, 3800, 3825, 3827, 3850, 3852, 3880, 3924, 3926, 3928, 3946, 3948, 3973, 3975, 3998, 4000, 4301, 4303, 4330, 4360, 4362, 4395, 4397, 4399, 4422, 4424, 4451, 4481, 4483, 4516, 4518, 4520, 4835, 4854, 4929, 4948, 5001, 5023, 5054, 5094, 5138, 5161, 5217, 5263], 'Google': [348, 379, 413, 456, 495, 530, 556, 587, 621, 664, 703, 738, 1049, 1076, 1107, 1142, 1171, 1202, 1236, 1263, 1294, 1329, 1358, 1389, 1693, 1720, 1759, 1791, 1833, 1860, 1887, 1926, 1958, 2000, 2310, 2373, 2419, 2479, 2545, 2572, 2635, 2681, 2741, 2807, 3061, 3104, 3137, 3181, 3223, 3250, 3293, 3326, 3370, 3412, 3733, 3781, 3801, 3828, 3853, 3881, 3929, 3949, 3976, 4001, 4304, 4331, 4363, 4400, 4425, 4452, 4484, 4521, 4836, 4855, 4884, 4930, 4949, 4978], 'Scholar2.': [349, 557, 1050, 1237, 1694, 1861, 2311, 2573, 3062, 3251, 3734, 3882, 4305, 4426, 4810, 4904], 'Caiozzo': [350, 381, 415, 458, 501, 558, 589, 623, 666, 709], 'VJ': [351, 382, 416, 459, 502, 559, 590, 624, 667, 710], 'Baker': [353, 384, 418, 464, 561, 592, 626, 672], 'Baldwin': [356, 387, 430, 470, 504, 564, 595, 638, 678, 712], 'KM.': [357, 388, 431, 471, 505, 565, 596, 639, 679, 713], 'Modulation': [358, 566], 'myosin': [360, 433, 507, 568, 641, 715, 2193, 2197, 2219, 2919, 3079, 3122, 3163, 3208, 3268, 3311, 3352, 3397, 5232], 'mechanical': [364, 402, 480, 572, 610, 688], 'loading:': [365, 573], 'role': [366, 574], 'stimulation': [368, 576], 'frequency.': [369, 577], 'Physiol': [372, 406, 445, 449, 486, 488, 519, 523, 580, 614, 653, 657, 694, 696, 727, 731, 1038, 1042, 1101, 1196, 1225, 1229, 1288, 1383, 1685, 1752, 1780, 1784, 1822, 1826, 1852, 1919, 1947, 1951, 1989, 1993, 3095, 3097, 3284, 3286, 3821, 3969, 4356, 4477, 4807, 4901], '82:': [373, 581], '211–218,': [374, 582], '1997.Link': [375, 583], 'ISI': [377, 411, 454, 493, 528, 585, 619, 662, 701, 736, 1047, 1074, 1105, 1140, 1169, 1234, 1261, 1292, 1327, 1356, 1691, 1718, 1757, 1789, 1831, 1858, 1885, 1924, 1956, 1998, 2308, 2371, 2417, 2477, 2543, 2570, 2633, 2679, 2739, 2805, 3059, 3102, 3135, 3179, 3221, 3248, 3291, 3324, 3368, 3410, 3731, 3779, 3799, 3826, 3851, 3879, 3927, 3947, 3974, 3999, 4302, 4329, 4361, 4398, 4423, 4450, 4482, 4519, 4834, 4928], 'Scholar3.': [380, 588, 1077, 1264, 1721, 1888, 2374, 2636, 3105, 3294, 3782, 3930, 4332, 4453, 4837, 4931], 'Novel': [389, 597, 5196], 'transitions': [390, 598], 'isoforms:': [393, 601], 'separate': [394, 602], 'combined': [396, 604, 2228], 'effects': [397, 478, 605, 686, 1437, 1677, 1844, 4207, 5122], 'thyroid': [399, 607], 'unloading.': [403, 611], '85:': [407, 615, 4392, 4513], '2237–2248,': [408, 616], '1998.Link': [409, 617], 'Scholar4.': [414, 622, 1108, 1295, 1760, 1927, 2420, 2682, 3138, 3327, 3802, 3950, 4364, 4485, 4856, 4950], 'Huang': [421, 629], 'K': [422, 630], 'Chou': [424, 632], 'H': [425, 633, 2343, 2425, 2605, 2687], 'Wu': [427, 635, 2424, 2433, 2686, 2695], 'YZ': [428, 636], 'Single-fiber': [432, 506, 640, 714], 'heavy': [434, 508, 642, 716, 2194, 2920, 3080, 3123, 3164, 3269, 3312, 3353, 5233], 'chain': [435, 509, 643, 717, 3081, 3165, 3270, 3354, 5234], 'polymorphism:': [436, 644], 'how': [437, 645], 'many': [438, 646], 'patterns': [439, 647], 'what': [441, 649], 'proportions?': [442, 650], 'Am': [443, 484, 517, 651, 692, 725, 1036, 1223, 1778, 1820, 1945, 1987, 3093, 3282, 4806, 4900], 'Regul': [446, 520, 654, 728, 1039, 1226, 1781, 1823, 1948, 1990], 'Integr': [447, 521, 655, 729, 1040, 1227, 1782, 1824, 1949, 1991], 'Comp': [448, 522, 656, 730, 1041, 1228, 1783, 1825, 1950, 1992], '285:': [450, 658], 'R570–R580,': [451, 659], '2003.Link': [452, 660], 'Scholar5.': [457, 665, 1143, 1330, 1792, 1959, 2480, 2742, 3182, 3371, 3829, 3977], 'Haddad': [461, 669], 'F': [462, 670, 2337, 2599], 'M': [465, 673, 1672, 1839, 2340, 2491, 2602, 2753, 3070, 3259, 3751, 3834, 3899, 3982], 'McCue': [467, 675], 'S': [468, 676, 1723, 1797, 1890, 1964, 2319, 2488, 2581, 2750, 3140, 3329, 3831, 3979], 'polymorphism': [473, 510, 681, 718], 'rodent': [475, 683, 4056, 4082, 5038], 'plantaris': [476, 684], 'muscle:': [477, 685], 'overload': [481, 689], 'hypothyroidism.': [483, 516, 691, 724], 'Cell': [487, 695, 3096, 3171, 3285, 3360, 5162], '278:': [489, 524, 697, 732], 'C709–C717,': [490, 698], '2000.Link': [491, 526, 699, 734], 'Scholar6.': [496, 704, 1172, 1359], 'di': [497, 705], 'Maso': [498, 706], 'NA': [499, 707], 'postnatal': [512, 720], 'development:': [513, 721], 'modulation': [514, 722], 'R1099–R1106,': [525, 733], 'ScholarREFERENCES1.': [531, 1203, 1834, 2546, 3224, 3854, 4401, 4885], 'ScholarREPEATABILITY': [739], 'NECESSARY': [742], 'BUT': [743], 'NOT': [744], 'SUFFICIENT': [745], 'CRITERION': [746], 'VALIDATING': [748], 'MEASUREMENTS': [749], 'ENDURANCETheodore': [751], 'Garland,': [752], 'Jr..Author': [753], 'AffiliationsProfessor': [754], 'Department': [755, 2011, 2812, 3422], 'Biology': [757], 'University': [758, 2014, 2816, 4529, 4848, 4942], 'Riverside.to': [761], 'Scientists': [764], 'risk': [765], 'gathering': [766], 'bad': [767, 818], 'data': [768, 819, 972, 4235, 4276], 'venturing': [770], 'into': [771, 2832, 2898], 'unfamiliar': [772], 'territory': [773], 'another': [775], 'discipline': [776], '(2).': [777], 'And,': [778], 'quote': [780], 'Darwin': [781], 'his': [783], '1871': [784], 'book': [785], 'Descent': [787], 'Man': [789], 'Selection': [791], 'Relation': [793], 'Sex,': [795], '“False': [796], 'facts': [797], 'highly': [799], 'injurious': [800], 'progress': [803], 'science,': [805], 'they': [807, 1612, 2997, 3166, 3355], 'often': [808, 4216], 'long': [809], 'endure': [810], '…”': [811], 'efficient': [814], 'way': [815, 3700], 'avoid': [817, 3632], 'collaborate': [822], 'appropriate': [824, 2150], 'experts.Working': [825], 'collaborators,': [827], 'I': [828, 993, 2260, 3067, 3256, 4561, 4718], 'have': [829, 3559, 4608, 4620], 'developed': [830], 'some': [831, 898, 4094], 'expertise': [832], 'measuring': [834], 'endurance': [835, 926, 1190, 1377, 1442, 1811, 1978, 2130, 2405, 2667, 3612, 3813, 3961, 4143, 4346, 4467], 'small': [837, 2969, 4232], 'vertebrates': [838], '(e.g.,': [839], '1,': [840], '5,': [841, 5167], '6,': [842], 'references': [844], 'therein),': [845], 'including': [846, 1507], 'laboratory': [847, 1415, 2890, 2982], 'mice': [848, 1123, 1310, 3533], '(4).': [849, 1578, 4163], 'Experience': [850], 'difficult': [857, 2086, 2107, 4673], 'task.': [858], 'Obviously,': [859], 'testing': [860, 906], 'equipment': [861], 'will': [862, 876, 4736], 'differ': [863], 'fish,': [865], 'terrestrial': [866], 'salamanders,': [867], 'mice.': [869, 1100, 1287, 1777, 1819, 1944, 1986], 'Beyond': [870], 'this,': [871], 'criteria': [872, 1453, 2095, 4546], 'defining': [874, 2051], 'exhaustion': [875, 2079, 4063], 'vary,': [877], 'sometimes': [878], 'because': [879, 1408, 4093], 'animals': [880, 1012, 1489, 1574, 1610, 2059, 4095], 'maintained': [883], 'intact': [884], 'subsequent': [886], 'study': [887, 1462, 4088], 'rather': [888], 'than': [889, 2087, 2218, 3622, 3659, 4623], 'killed': [890], 'determine,': [892], 'say,': [893], 'tissue': [894], 'glycogen': [895, 4378, 4499], 'concentrations.': [896], 'Moreover,': [897, 4164], 'individuals': [899], 'adopt': [900], 'defensive': [901], 'behaviors': [902, 1098, 1285], 'preclude': [904], 'locomotor': [905, 1187, 1374], '(see': [907], '2).': [909], 'But': [910], 'cases,': [913], 'possible': [917, 933, 1597, 4205], 'obtain': [919, 4263], 'at': [920], 'least': [921], 'two': [922, 938, 4292, 4413], 'replicate': [923], 'measures': [924, 4118], '(from': [927], 'cooperative': [928], 'individuals),': [929], 'which': [930, 2954, 4152, 4641], 'help': [931], 'address': [932], 'methodological': [934], 'issues.': [935], 'From': [936, 5211], 'these,': [937], 'simple': [939, 2091], 'but': [940, 1006, 1524, 4127, 5240], 'analyses': [942, 948], 'always': [944], 'reported': [946], '(although': [947], 'repeatability': [950], 'take': [952, 4787], 'various': [953], 'forms,': [954], 'e.g.,': [955], '3):': [956], '1)': [957], 'Pearson': [959], 'correlation': [960, 1026, 1151, 1213, 1338, 4218], 'index': [962], 'relative': [963], 'consistency': [964, 995], 'individual': [966, 997, 1414, 2186], '(possibly': [968], 'after': [969], 'transforming': [970], 'make': [974], 'more': [976, 1418, 2085, 2882, 3545, 3616, 3658, 4621], 'nearly': [977], 'bivariate': [978], 'normal);': [979], '2)': [980], 'paired': [982], 't-test': [983], 'indicate': [985, 4591], 'if': [986, 1611], 'performance': [987, 1567, 1586, 1638, 1649], 'changes,': [988], 'average,': [990], 'trials.': [992], 'view': [994], 'as': [999, 1478, 1494, 1496, 1528, 2189, 2959, 3562, 3611, 3653, 4660, 4711], 'necessary': [1000], 'validate': [1002], 'measurement': [1004], 'protocol,': [1005], 'sufficient': [1008], 'were': [1013], 'performing': [1014], 'exhaustion.REFERENCES1.': [1016], 'Bennett': [1017, 1204], 'AF': [1018, 1205], 'Garland': [1020, 1118, 1147, 1179, 1207, 1305, 1334, 1366], 'T': [1021, 1085, 1180, 1208, 1272, 1367, 1794, 1961], 'Else': [1023, 1210], 'PL.': [1024, 1211], 'Individual': [1025, 1212, 5173], 'morphology,': [1028, 1215], 'mechanics': [1030, 1217], 'locomotion': [1032, 1219], 'salamander.': [1035, 1222], '256:': [1043, 1230], 'R1200–R1208,': [1044, 1231], '1989.Link': [1045, 1232], 'doi:10.1152/japplphysiol.00125.2009.': [1073, 1260, 1717, 1884, 3058, 3247, 4328, 4449, 4833, 4927], 'Knab': [1078, 1265], 'AM': [1079, 1266, 2328, 2590], 'Bowen': [1081, 1268], 'RS': [1082, 1269], 'Moore-Harrison': [1084, 1271], 'Hamilton': [1087, 1274], 'AT': [1088, 1275], 'Turner': [1090, 1277], 'Lightfoot': [1093, 1280], 'JT.': [1094, 1281], 'Repeatability': [1095, 1149, 1282, 1336], 'Behav.': [1102, 1289], 'In': [1103, 1167, 1290, 1354, 2110, 2922, 3007, 4033], 'press.': [1104, 1168, 1291, 1355], 'Meek': [1109, 1296], 'TH': [1110, 1297], 'Lonquich': [1112, 1299], 'BP': [1113, 1300], 'Hannon': [1115, 1302], 'RM': [1116, 1303], 'T.': [1119, 1148, 1306, 1335], 'Endurance': [1120, 1307, 2513, 2775, 4993], 'capacity': [1121, 1308, 1812, 1979, 2131, 4256, 4347, 4468], 'selectively': [1124, 1311], 'bred': [1125, 1312], 'high': [1127, 1314, 4171, 4183, 4267], 'voluntary': [1128, 1315, 1732, 1899], 'wheel': [1129, 1316, 1733, 1900], 'running.': [1130, 1317], 'Exp': [1132, 1319], 'Biol': [1133, 1320], '212:': [1134, 1321], '2908–2917,': [1135, 1322], '2009.Crossref': [1136, 1323, 3797, 3945], 'PubMed': [1138, 1325, 2369, 2415, 2475, 2541, 2631, 2677, 2737, 2803, 3133, 3177, 3219, 3322, 3366, 3408, 3777, 3925, 4396, 4517], 'Oufiero': [1144, 1331], 'CE': [1145, 1332], 'swimming': [1153, 1340], 'performances': [1154, 1341], 'size': [1156, 1343], 'over': [1157, 1344], 'varying': [1158, 1345], 'time-scales': [1159, 1346], 'guppy': [1162, 1349], '(Poecilia': [1163, 1350], 'reticulata).': [1164, 1351], 'Funct': [1165, 1352], 'Ecol.': [1166, 1353], 'Sorci': [1173, 1360], 'G': [1174, 1361], 'Swallow': [1176, 1363], 'JG': [1177, 1364], 'Clobert': [1182, 1369], 'Quantitative': [1184, 1371], 'genetics': [1185, 1372], 'speed': [1188, 1375], 'lizard': [1193, 1380], 'Lacerta': [1194, 1381], 'vivipara.': [1195, 1382], 'Zool': [1197, 1384], '68:': [1198, 1385], '698–720,': [1199, 1386], '1995.Crossref': [1200, 1387, 3175, 3364], 'ScholarWataru': [1390], 'Aoi.Author': [1391], 'AffiliationsAssociate': [1392, 2810], 'Professor': [1393, 2811], 'Laboratory': [1394], 'Health': [1396], 'Science': [1397, 5026], 'Kyoto': [1398], 'Prefectural': [1399], 'University.to': [1400, 4030], 'Animal': [1403], 'model': [1404, 4057], 'studies': [1405, 2057, 2283], 'useful': [1407], 'less': [1409, 1422, 2216], 'unevenness': [1410], 'seen': [1412], 'animals,': [1416], 'uniform': [1419], 'characteristics': [1420, 3447], 'sampling': [1423], 'bias': [1424], 'experimental': [1426, 2134, 2823, 2891, 4068, 4167], 'groups.': [1427], 'benefits': [1429], 'especially': [1431], 'important': [1432, 1664, 2173, 4545], 'we': [1434, 2155, 2244, 2269, 3676, 3692], 'investigate': [1435], 'nutritional': [1439, 1593], 'state': [1440], 'fatigue': [1444, 1467, 1651, 2240, 4048, 4120, 4136, 4161], 'induced': [1445, 2979], 'exercise.': [1447, 4865, 4959], 'On': [1448, 1482, 3500], 'basis': [1450], 'stated': [1454], '(2),': [1459], 'authors': [1464, 4564], 'examined': [1465], 'exercise-induced': [1466], 'association': [1469], 'energy': [1471, 3626], 'regulation': [1473], 'aerobic': [1475], 'exercise,': [1476, 1629, 3675], 'such': [1477, 2188, 3557, 3610, 3652, 3684, 4704], 'running': [1479, 1734, 1901, 2142, 4078, 4100], 'swimming.': [1481], 'other': [1484, 2267, 2907, 3502], 'hand,': [1485, 3503], 'forced': [1486, 1538, 4059], 'entails': [1490], 'great': [1491], 'mental': [1492, 1554], 'stress': [1493, 1498, 1746, 1913], 'well': [1495], 'physical': [1497, 1637, 3505, 3608], 'strongly': [1501], 'affected': [1502, 4596], 'endocrine': [1505], 'system,': [1506], 'glucocorticoids': [1508], 'catecholamines': [1510], '(1,': [1511, 3567, 4236], '3).': [1512, 3568, 4237], 'Consideration': [1513], 'peripheral': [1521], 'capacity,': [1523], 'emotional': [1526, 1548], 'factors,': [1527], 'affect': [1531], 'tolerance.': [1533], 'Taken': [1534], 'together,': [1535], 'researchers': [1536], 'employing': [1537], 'activity': [1539, 2199, 2221, 3506], 'need': [1540, 4635], 'aware': [1543], 'effect': [1546, 5155], 'fatigue,': [1549], 'strive': [1551], 'prepare': [1553], 'stress-free': [1555], 'conditions.': [1556], 'worthy': [1560], 'attention': [1562], 'degree': [1565, 1602, 4268], 'elevation': [1568], 'through': [1569, 1605], 'training': [1570, 1606, 1772, 1939, 2514, 2776, 5126], 'large': [1572, 1608, 2971], 'compared': [1575], 'humans': [1577, 2516, 2778, 2904], 'Furthermore,': [1579, 3606], 'observed': [1583], 'tends': [1587, 1639], 'easily': [1590], 'improved': [1591], 'intervention': [1594], '(5).': [1595, 2961, 3454], 'One': [1596], 'reason': [1598], 'adaptation': [1604, 2403, 2665], 'kept': [1614], 'narrow': [1617], 'cage': [1618], 'birth,': [1620], 'usually': [1623], 'opportunities': [1625], 'positively': [1627], 'whereas': [1630], 'healthy': [1632], 'humans,': [1633, 2995], 'level': [1635], 'uniform.': [1642], 'Considering': [1643], 'above': [1645], 'points,': [1646], 'examinations': [1647], 'using': [1652, 2868, 4188], 'animal': [1653, 2869, 2892, 2983, 3648], 'models': [1654, 3649], 'conducted': [1657], 'caution': [1659, 3634], 'understanding': [1661], 'humans.REFERENCES1.': [1667], 'Blustein': [1668, 1835], 'JF': [1669, 1836], 'Mclaughlin': [1671, 1838], 'Holfman': [1674, 1841], 'JR.': [1675, 1842], 'Exercise': [1676, 1843, 4844, 4869, 4938, 4963, 4994], 'stress-induced': [1678, 1845], 'analgesia': [1679, 1846], 'spatial': [1681, 1848], 'learning': [1682, 1849], 'rats.': [1684, 1749, 1851, 1916, 4353, 4474], 'Behav': [1686, 1853], '89:': [1687, 1854], '582–586,': [1688, 1855], '2006.Crossref': [1689, 1856], 'Fediuc': [1722, 1889], 'Campbell': [1725, 1892], 'JE': [1726, 1893], 'Riddell': [1728, 1895], 'MC.': [1729, 1896], 'Effect': [1730, 1897], 'circadian': [1736, 1903], 'corticosterone': [1737, 1904], 'release': [1738, 1905], 'HPA': [1741, 1908], 'axis': [1742, 1909], 'responsiveness': [1743, 1910], 'restraint': [1745, 1912], 'Sprague-Dawley': [1748, 1915, 4352, 4473], '100:': [1753, 1920], '1867–1875,': [1754, 1921], '2006.Link': [1755, 1922], 'Massett': [1761, 1928], 'MP': [1762, 1929], 'Berk': [1764, 1931], 'BC.': [1765, 1932], 'Strain-dependent': [1766, 1933], 'responses': [1769, 1936, 4745], 'inbred': [1774, 1941], 'hybrid': [1776, 1943], '288:': [1785, 1827, 1952, 1994], 'R1006–R1013,': [1786, 1953], '2005.Link': [1787, 1829, 1954, 1996], 'Murase': [1793, 1960], 'Haramizu': [1796, 1963], 'Shimotoyodome': [1799, 1966], 'Nagasawa': [1802, 1969], 'Tokimitsu': [1805, 1972], 'I.': [1806, 1973, 4020], 'Green': [1807, 1974], 'tea': [1808, 1975], 'extract': [1809, 1976], 'improves': [1810, 1977], 'increases': [1814, 1981, 2521, 2783], 'lipid': [1816, 1983], 'oxidation': [1817, 1984], 'R708–R715,': [1828, 1995], 'ScholarFOR': [2001], 'PRAGMATIC': [2003], 'APPROACH': [2004], 'TO': [2005], 'EXERCISE': [2006], 'STUDIESChristoph': [2007], 'Handschin,': [2008], '.Author': [2009, 2019, 2025, 2033], 'AffiliationsBiozentrum,': [2010], 'Pharmacology/Neurobiology': [2013], 'Basel,': [2016], 'Switzerland.Serge': [2017], 'Summermatter,': [2018], 'Basel.Nathan': [2022], 'K.': [2023], 'LeBrasseur,': [2024], 'AffiliationsPfizer': [2026], 'Global': [2027], 'Development.Jiandie': [2030], 'Lin,': [2031], 'Michigan.Bruce': [2036], 'Spiegelman.Author': [2038], 'AffiliationsHarvard': [2039], 'Medical': [2040], 'School.to': [2041], 'skeptical': [2046], 'about': [2047, 2175], 'feasibility': [2049], 'gold': [2053, 4638, 4738], 'standard': [2054, 3014], 'huge': [2062], 'variety': [2063], 'strain,': [2065], 'age,': [2066], 'sex,': [2067], 'transgenesis': [2068], 'paradigms': [2071], 'For': [2073], 'example,': [2074], 'practical': [2076], 'rodents': [2081], '(and': [2082], 'humans)': [2083], 'implied': [2088], 'theoretical': [2092], 'definition.': [2093], 'proposed': [2096], 'invasive,': [2102], 'disruptive,': [2103], 'terminal,': [2104], 'ethically': [2106], 'justify.': [2109], 'contrast,': [2111], 'electric': [2112], 'shock': [2113], 'stimulation,': [2114], 'particular': [2116], 'combination': [2118, 2212], 'computer-controlled': [2120], 'break-off': [2121], 'criteria,': [2122], 'pragmatic,': [2125], 'non-invasive': [2126], 'solution': [2127], 'comparing': [2129], 'groups,': [2135], 'even': [2136, 2881], 'longitudinal': [2138], 'Problems': [2140], 'style': [2143], 'noncompliance': [2145], 'overcome': [2148], 'acclimatization': [2151], 'group': [2153, 4201], 'size.Second,': [2154], 'certainly': [2156], 'appreciate': [2157], 'historic,': [2159], 'excellent': [2160], 'work': [2161], 'our': [2163, 2280, 3670, 3695], 'predecessors.': [2164], 'However,': [2165, 3569, 4560], 'novel': [2166, 2274], 'complementary': [2167], 'interdisciplinary': [2169], 'additional': [2172], 'details': [2174], 'characterization': [2180], '(3).': [2183, 4133], 'Even': [2184], 'so,': [2185], 'immunohistochemical': [2190], 'staining': [2191, 2200], 'chains,': [2195], 'matter,': [2203], 'fail': [2204], 'comprehensive': [2208], 'picture.': [2209], 'Therefore,': [2210, 4717], 'methods,': [2214], 'optimally': [2215, 2227, 4197], 'delicate': [2217], 'determination,': [2222], 'used': [2225], 'allow': [2232, 4584], 'true': [2233], 'peak': [2236], 'force': [2237, 4734], 'generation': [2238], 'resistance': [2241], '(2,': [2242, 2947, 3476], '4).Finally,': [2243], 'think': [2245], 'instead': [2247], 'dogmatic': [2250], 'concepts': [2254], '[i.e.,': [2255], '“no': [2256], 'increase': [2257, 2263], 'type': [2259, 2917, 2946, 3005, 3086, 3275], 'fibers”': [2261], 'vs.': [2262], '(5)': [2265], 'references],': [2268], 'remain': [2271], 'open': [2272], 'findings': [2275, 3643, 5041], 'continue': [2277], 'improve': [2279], 'accordingly.REFERENCES1.': [2284], 'doi:10.115/japplphysiol.00125.2009.': [2307, 2569], 'Delbono': [2312, 2574], 'O': [2313, 2437, 2575, 2699], 'Xia': [2315, 2577], 'Treves': [2318, 2580], 'Wang': [2321, 2583], 'ZM': [2322, 2584], 'Jimenez-Moreno': [2324, 2586], 'R': [2325, 2455, 2587, 2717], 'Payne': [2327, 2589], 'Messi': [2330, 2592], 'ML': [2331, 2593], 'Briguet': [2333, 2595], 'Schaerer': [2336, 2598], 'Nishi': [2339, 2601], 'Takeshima': [2342, 2604], 'Zorzato': [2345, 2607], 'F.': [2346, 2608], 'Loss': [2347, 2609], 'skeletal': [2349, 2534, 2611, 2796, 3091, 3157, 3280, 3346, 3436, 3457, 3511, 3583, 3629, 3766, 3810, 3914, 3958, 5238], 'strength': [2351, 2613], 'ablation': [2353, 2615], 'sarcoplasmic': [2356, 2618], 'reticulum': [2357, 2619], 'protein': [2358, 2620, 5228], 'JP45.': [2359, 2621], 'Proc': [2360, 2622, 3768, 3916], 'Natl': [2361, 2623, 3769, 3917], 'Acad': [2362, 2624, 3770, 3918], 'Sci': [2363, 2625, 3771, 3919], 'USA': [2364, 2626, 3772, 3920], '104:': [2365, 2627, 3773, 3921], '20108–20113,': [2366, 2628], '2007.Crossref': [2367, 2413, 2629, 2675, 3775, 3923], 'Keller': [2375, 2637], 'P': [2376, 2443, 2638, 2705, 3736, 3884], 'Vollaard': [2378, 2640], 'N': [2379, 2641], 'Babraj': [2381, 2643], 'Ball': [2384, 2646], 'D': [2385, 2647], 'Sewell': [2387, 2649], 'DA': [2388, 2650], 'Timmons': [2390, 2652], 'JA.': [2391, 2653], 'Using': [2392, 2654, 5018], 'systems': [2393, 2655], 'biology': [2394, 2656], 'define': [2396, 2658], 'essential': [2398, 2660], 'biological': [2399, 2661], 'networks': [2400, 2662], 'responsible': [2401, 2663], 'training.': [2407, 2669], 'Biochem': [2408, 2670, 3125, 3314], 'Soc': [2409, 2671], 'Trans': [2410, 2672], '35:': [2411, 2673], '1306–1309,': [2412, 2674], 'Lin': [2421, 2683], 'Tarr': [2427, 2689], 'PT': [2428, 2690], 'Zhang': [2430, 2692], 'CY': [2431, 2693], 'Z': [2434, 2696], 'Boss': [2436, 2698], 'Michael': [2439, 2701], 'LF': [2440, 2702], 'Puigserver': [2442, 2704], 'Isotani': [2445, 2707], 'E': [2446, 2708, 3748, 3896], 'Olson': [2448, 2710], 'EN': [2449, 2711], 'Lowell': [2451, 2713], 'BB': [2452, 2714], 'Bassel-Duby': [2454, 2716], 'Spiegelman': [2457, 2719], 'BM.': [2458, 2720], 'Transcriptional': [2459, 2721], 'co-activator': [2460, 2722], 'PGC-1': [2461, 2723], 'alpha': [2462, 2724], 'drives': [2463, 2725], 'formation': [2465, 2727], 'slow-twitch': [2467, 2729], 'fibres.': [2469, 2731], 'Nature': [2470, 2732], '418:': [2471, 2733], '797–801,': [2472, 2734], '2002.Crossref': [2473, 2735], 'Russell': [2481, 2743], 'AP': [2482, 2744], 'Feilchenfeldt': [2484, 2746], 'Schreiber': [2487, 2749], 'Praz': [2490, 2752], 'Crettenand': [2493, 2755], 'Gobelet': [2496, 2758], 'C': [2497, 2759, 4858, 4952], 'Meier': [2499, 2761], 'CA': [2500, 2762, 3107, 3296], 'Bell': [2502, 2764], 'DR': [2503, 2765], 'Kralli': [2505, 2767], 'Giacobino': [2508, 2770], 'JP': [2509, 2771], 'Deriaz': [2511, 2773], 'O.': [2512, 2774], 'leads': [2517, 2779, 3028], 'type-specific': [2520, 2782], 'levels': [2523, 2785, 5229, 5244], 'peroxisome': [2525, 2530, 2787, 2792], 'proliferator-activated': [2526, 2531, 2788, 2793], 'receptor-gamma': [2527, 2789], 'coactivator-1': [2528, 2790], 'receptor-alpha': [2532, 2794], 'muscle.': [2535, 2797, 3092, 3281, 3630, 3767, 3915], 'Diabetes': [2536, 2798, 3497], '52:': [2537, 2799], '2874–2881,': [2538, 2800], '2003.Crossref': [2539, 2801], 'ScholarLuisa': [2808], 'Gorza.Author': [2809], 'Biomedical': [2814], 'Sciences': [2815], 'Padova,': [2818], 'Italy.to': [2819], 'Good': [2822], 'practice': [2824], 'figured': [2828], 'out': [2829], 'without': [2830], 'taking': [2831], 'account': [2833], 'previous': [2834], 'experience': [2835], 'answering': [2837], 'basic': [2838], 'questions,': [2839], 'those': [2841], 'arisen': [2842], 'Viewpoint': [2845], '(1)': [2850], 'represent': [2851], 'starting': [2853], 'point': [2854], 'toward': [2855], 'significant': [2857], 'advance': [2858], 'common': [2861], 'knowledge': [2862], 'biochemistry': [2865], 'physiology': [2867], 'models.': [2870], 'requirement': [2872], 'shared': [2874], 'fiber-type': [2878], 'classification': [2879], 'becomes': [2880], 'critical': [2883], 'results': [2886], 'obtained': [2887, 3644], 'going': [2894], 'translated': [2897], 'human': [2899, 3090, 3156, 3279, 3345, 5043], 'Skeletal': [2901, 3478, 4376, 4497, 5075, 5085, 5213], '(2)': [2905, 4040, 4538], 'mammals,': [2908], 'like': [2909], 'pig,': [2910], 'cat,': [2911], 'baboon': [2913], '(3),': [2914], 'lack': [2915], '2B': [2918, 2944], 'chain.': [2921], 'species,': [2924], 'fast': [2926, 3120, 3309], 'population': [2928], 'composed': [2930], '2A': [2932], '2X': [2934], 'types,': [2936], 'one': [2939], 'corresponding': [2940], 'old': [2943], '4),': [2948], 'displaying': [2950], 'pattern,': [2953], 'hardly': [2956], 'defined': [2958], 'glycolytic': [2960], 'partial': [2963], 'correspondence': [2964], 'mammals': [2972], 'does': [2973, 4582], 'exclude': [2975], 'changes': [2978, 3537, 3667], 'inactivity': [2988], 'would': [2989], 'mimic': [2990, 3522], 'events': [2992], 'occurring': [2993, 3668], 'although': [2996], 'might': [2998], 'imply': [2999], 'differential': [3001], 'involvement': [3002], 'populations.': [3006], 'context,': [3009], 'use': [3012, 4683], 'characterize': [3017], 'myofiber': [3018], 'either': [3021], 'redistributive': [3026], 'basis,': [3027], 'formulation': [3031], 'sound': [3033], 'mechanistic': [3034], 'hypotheses.REFERENCES1.': [3035], 'Smerdu': [3063, 3252], 'V': [3064, 3253, 4372, 4493], 'Karsch-Mizrachi': [3066, 3255], 'Campione': [3069, 3258], 'Leinwand': [3072, 3261], 'L': [3073, 3262], 'Schiaffino': [3075, 3264, 3830, 3978], 'S.': [3076, 3265, 5253], 'Type': [3077, 3266, 3495, 5009, 5090, 5108], 'transcripts': [3082, 3271], 'expressed': [3084, 3273], 'IIb': [3087, 3276], '267:': [3098, 3287], 'C1723–C1728,': [3099, 3288], '1994.Link': [3100, 3289], 'Lucas': [3106, 3295], 'Kang': [3109, 3298], 'LHD': [3110, 3299], 'Hoh': [3112, 3301], 'JFY.': [3113, 3302], 'Monospecific': [3114, 3303], 'antibodies': [3115, 3304], 'against': [3116, 3305], 'three': [3118, 3307], 'mammalian': [3119, 3308], 'limb': [3121, 3310], 'chains.': [3124, 3313], 'Biophys': [3126, 3315], 'Res': [3127, 3170, 3316, 3359, 4390, 4511], 'Comm': [3128, 3317], '272:': [3129, 3318], '303–308,': [3130, 3319], '2000.Crossref': [3131, 3320], 'Ennion': [3139, 3328], 'SantÂ-ana': [3142, 3331], 'Pereira': [3143, 3332], 'Sargeant': [3146, 3335], 'AJ': [3147, 3336], 'Young': [3149, 3338], 'Goldspink': [3152, 3341], 'G.': [3153, 3342, 5250], 'Characterization': [3154, 3343], 'fibres': [3159, 3348], 'according': [3160, 3349], 'express.': [3167, 3356], 'Muscle': [3169, 3358, 5007, 5076, 5086, 5101], 'Motil': [3172, 3361], '16:': [3173, 3362], '35–43,': [3174, 3363], 'Hintz': [3183, 3372], 'CS': [3184, 3373], 'Coyle': [3186, 3375, 3806, 3954], 'EF': [3187, 3376], 'Kaiser': [3189, 3378], 'KK': [3190, 3379], 'Chi': [3192, 3381], 'MMY': [3193, 3382], 'Lowry': [3195, 3384], 'OH.': [3196, 3385], 'Comparison': [3197, 3386], 'typing': [3201, 3390], 'quantitative': [3203, 3392], 'enzyme': [3204, 3393], 'assays': [3205, 3394], 'staining.': [3210, 3399], 'Histochem': [3212, 3401], 'Cytochem': [3213, 3402], '32:': [3214, 3403], '655–660,': [3215, 3404], '1984.': [3216, 3405], 'Crossref': [3217, 3406, 4853, 4947], 'ScholarEXERCISE—BEYOND': [3413], 'SKELETAL': [3414], 'MUSCLE': [3415], 'ENERGY': [3416], 'METABOLISMPablo': [3417], 'Garcia-Roves.Author': [3419], 'AffiliationsSenior': [3420], 'Researcher': [3421], 'Physiology': [3424, 3846, 3994, 4027, 4528], 'Pharmacology': [3426], 'Karolinska': [3427], 'Institutet': [3428], 'Stockholm,': [3429], 'Sweden.to': [3430], 'consequence': [3441], 'acquired': [3448], 'differentiation': [3450], '(muscle': [3451], 'cell': [3452], 'signature)': [3453], 'Nevertheless,': [3455], 'mature': [3456], 'cells': [3459], 'metabolically': [3461], 'flexible': [3462], 'adapt': [3464], 'short-': [3469], 'long-term': [3471], 'adjustments': [3472], 'substrate': [3474], 'utilization': [3475, 3486], '4).': [3477], 'main': [3482], 'contributor': [3483], 'glucose': [3485], 'potential': [3490, 3564], 'partially': [3492], 'lost': [3493], '2': [3496], 'Mellitus': [3498], '(T2DM).': [3499], 'regular': [3504, 3607, 3674], 'provokes': [3507], 'adaptations': [3509, 3558, 3685], '(4)': [3513, 4659], 'prevent': [3516, 3597], 'T2DM.': [3517], 'Hence,': [3518], 'pharmacological': [3519, 3689], '“exercise': [3525], 'responses”': [3526], 'demand.': [3529], 'Transgenic': [3530], 'technology': [3531], 'gene': [3539], 'lead': [3542, 4244], 'oxidative': [3546], 'insulin': [3548], 'consequently': [3552], 'compounds': [3553], 'able': [3554, 3681], 'reproduce': [3556], 'claimed': [3561], 'exercise-like': [3565], 'alternative': [3566], 'key': [3571], 'components': [3572], 'pathways,': [3575], 'controlling': [3576, 3841, 3989], 'signature': [3579], 'developmental': [3587], 'stages,': [3588], 'necessarily': [3591], 'interest': [3593], 'attempting': [3595, 3639], 'treat': [3599], 'diseases': [3601], 'develop': [3603], 'adulthood.': [3605], 'activity,': [3609], 'training,': [3614], 'produces': [3615], 'improvements': [3618], 'organs': [3621], 'just': [3623], 'modifications': [3624], 'metabolism': [3627, 5040], 'misinterpretation,': [3633], 'taken': [3637], 'extrapolate': [3641], 'genetically': [3646], 'modified': [3647], 'viewpoints': [3651], 'welcome': [3660], 'Given': [3662], 'complexity': [3664], 'within': [3669], 'body': [3671], 'due': [3672], 'far': [3678], 'being': [3680], '“mimic”': [3683], 'genetic': [3687], 'interventions.': [3690], 'Instead,': [3691], 'put': [3694], 'efforts': [3696], 'finding': [3698], 'motivate': [3702], 'people': [3703], '(3).REFERENCES1.': [3706], 'doi:': [3729, 3877], '10.1152/japplphysiol.00125.2009.': [3730, 3878], 'Garcia-Roves': [3735, 3883], 'Huss': [3738, 3886], 'JM': [3739, 3887, 4282, 4403], 'Han': [3741, 3889], 'DH': [3742, 3890], 'Hancock': [3744, 3892], 'CR': [3745, 3893], 'Iglesias-Gutierrez': [3747, 3895], 'Chen': [3750, 3898], 'Holloszy': [3753, 3786, 3803, 3901, 3934, 3951], 'JO.': [3754, 3787, 3902, 3935], 'Raising': [3755, 3903], 'plasma': [3756, 3904], 'fatty': [3757, 3905], 'acid': [3758, 3906], 'concentration': [3759, 3907], 'induces': [3760, 3908], 'increased': [3761, 3909], 'biogenesis': [3762, 3910], 'mitochondria': [3764, 3912], '10709–10713,': [3774, 3922], 'Hawley': [3783, 3931], 'JA': [3784, 3932], 'Exercise:': [3788, 3936], "it's": [3789, 3937], 'real': [3791, 3939], 'thing!': [3792, 3940], 'Nutr': [3793, 3941], 'Rev': [3794, 3942], '67:': [3795, 3943], '172–178,': [3796, 3944], 'JO': [3804, 3952], 'EF.': [3807, 3955], 'Adaptations': [3808, 3956], 'their': [3816, 3964, 4034, 4588, 4597], 'consequences.': [3818, 3966], '56:': [3822, 3970], '831–838,': [3823, 3971], '1984.Link': [3824, 3972], 'Sandri': [3833, 3981], 'Murgia': [3836, 3984], 'Activity-dependent': [3838, 3986], 'signaling': [3839, 3987], 'pathways': [3840, 3988], 'diversity': [3843, 3991], 'plasticity.': [3845, 3993], '22:': [3847, 3995], '269–278,': [3848, 3996], '2007.Link': [3849, 3997], 'ScholarVALID': [4002], 'AND': [4003, 4011], 'REPRODUCIBLE': [4004], 'ENDURANCE': [4005], 'PROTOCOLS': [4006], 'UNDERLIE': [4007], 'DATA': [4008], 'INTERPRETATION,': [4009], 'INTEGRATION,': 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'periods,': [4106], 'turning': [4107], 'fight': [4109], 'grid,': [4111], 'etc.)': [4112], 'instances': [4116], 'objective': [4117], '(biochemical': [4121], 'otherwise)': [4123], 'achieved': [4126], 'discarded': [4132], 'When': [4134], 'prohibited': [4139], '(i.e.,': [4140], 'multiple': [4142], 'tests': [4144], 'required)': [4146], 'implement': [4149], 'protocols': [4150], 'termination': [4154], 'validated': [4157], 'previously': [4158], 'established': [4160, 4609, 4765], 'markers': [4162], 'refine': [4166], 'design': [4168], 'achieve': [4170, 4182, 4241], 'statistical': [4172], 'power,': [4173], 'evidence': [4177], 'ability': [4180, 4250], 'degrees': [4184], 'within-animal': [4186, 4211, 4270], 'reproducibility': [4187, 4242, 4271], 'protocol.': [4191], 'analysis': [4199, 4219], 'time/familiarization': [4206], 'conjunction': [4209], 'coefficients': [4212], 'variation.': [4214], 'cited': [4217], 'poor': [4222], 'measure': [4223], 'reproducibility,': [4225], 'particularly': [4226], 'relatively': [4231], 'range': [4233], 'inability': [4239], 'inappropriate': [4246], 'physiological': [4247], 'conclusions.': [4248, 4598], 'accurately': [4253], "animal's": [4255], 'run': [4258], 'report': [4265], 'vital': [4273], 'accurate': [4275], 'interpretation,': [4277], 'integration,': [4278], 'application.REFERENCES1.': [4280], 'Bland': [4281, 4402], 'Altman': [4284, 4405], 'DG.': [4285, 4406], 'Statistical': [4286, 4407], 'agreement': [4290, 4411], 'clinical': [4295, 4416], 'agreement.': [4296, 4417], 'Lancet': [4297, 4418], 'i:': [4298, 4419], '307–310,': [4299, 4420], '1986.Crossref': [4300, 4421], 'Copp': [4333, 4454], 'SW': [4334, 4455], 'Davis': [4336, 4457], 'RT': [4337, 4458], 'Poole': [4339, 4460], 'DC': [4340, 4461], 'Musch': [4342, 4365, 4463, 4486], 'TI.': [4343, 4464], 'Reproducibility': [4344, 4465], 'VO2peak': [4349, 4470], 'male': [4351, 4472], '106:': [4357, 4478], '1072–1078,': [4358, 4479], '2009.Link': [4359, 4480], 'TI': [4366, 4487], 'Ghaul': [4368, 4489], 'MR': [4369, 4490], 'Tranchitella': [4371, 4492], 'Zelis': [4374, 4495], 'R.': [4375, 4496], 'depletion': [4379, 4500], 'submaximal': [4381, 4502], 'rats': [4384, 4505], 'chronic': [4386, 4507, 5124], 'heart': [4387, 4508], 'failure.': [4388, 4509], 'Basic': [4389, 4510], 'Cardiol': [4391, 4512], '606–618,': [4393, 4514], '1990.Crossref': [4394, 4515], 'ScholarCharles': [4522], 'Tipton,': [4524], 'PhD.Author': [4525], 'AffiliationsDepartment': [4526], 'Arizona.to': [4531], 'Dr.': [4534], 'colleagues': [4537], 'commended': [4542], 'issues': [4547], 'selecting': [4549], 'sciences': [4554], 'necessitate': [4556], 'deliberation': [4557], 'debate.': [4559], 'chastise': [4562], 'Editor': [4567, 4721, 4784], 'allowing': [4569], 'scientific': [4570, 4709], 'aspersions': [4571], 'caste': [4574], 'upon': [4575], 'eight': [4576], 'laboratories': [4577], 'format': [4580], 'them': [4585], 'defend': [4587], 'logic': [4589], 'whether': [4592], 'significantly': [4595], 'pleased': [4600], 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'Trained': [5111], 'MenJournal': [5112], 'Strength': [5114], 'Conditioning': [5116], 'Research,': [5117], '31,': [5119], '3The': [5121], 'status': [5127], 'motor': [5129], 'unit': [5130], 'activation': [5131], 'deactivation': [5133], 'control': [5134], 'strategies18': [5135], 'May': [5136], '2015': [5137], 'Sports': [5141], 'Sciences,': [5142], '34,': [5144], '3Mitochondrial': [5146], 'dysfunction-associated': [5147], 'OPA1': [5148], 'cleavage': [5149], 'contributes': [5150], 'degeneration:': [5153], 'preventative': [5154], 'hydroxytyrosol': [5157], 'acetate13': [5158], 'November': [5159], '2014': [5160], 'Death': [5163], 'Disease,': [5165], '11As': [5169], 'Sword': [5171], 'Grows:': [5172], 'Variation': [5174], 'Ontogenetic': [5176], 'Effects': [5177], 'Sexually': [5180], 'Selected': [5181], 'Trait': [5182], 'Locomotor': [5184], 'Performance': [5185], 'Xiphophorus': [5187], 'helleriiPhysiological': [5188], 'Biochemical': [5190], 'Zoology,': [5191], '85,': [5193], '6A': [5195], 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