Title: Ig-secreting and interferon-gamma-producing cells in mice mucosally immunized with influenza virus.
Abstract: 1. Oral immunization of mice with influenza virus type A/Udorn, induced antigen-specific IgA antibodies in external secretions (e.g., saliva and fecal extract). 2. Increased numbers of antigen-specific IgA spot-forming cells (SFC) were seen in mononuclear cells isolated from IgA-effector tissues (e.g., SG) of mice orally-immunized with influenza virus. 3. Following oral or systemic immunization of mice, IFN gamma-secreting cells (Th1 type) displayed a characteristic pattern of distribution which was related to the route of immunization.
Publication Year: 1995
Publication Date: 1995-01-01
Language: en
Type: article
Indexed In: ['pubmed']
Access and Citation
Cited By Count: 6
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