Title: [Therapeutical application of gammaglobulin preparations in inborn immunodeficiency syndromes (author's transl)].
Abstract:The therapeutical use of gammaglobulin preparations in inborn immunodeficiency syndromes should be performed critically and only if an immunoglobulin lack exists which can be substituted. Immunodefici...The therapeutical use of gammaglobulin preparations in inborn immunodeficiency syndromes should be performed critically and only if an immunoglobulin lack exists which can be substituted. Immunodeficiency defects are listed according to the WHO-classification. For substitution of immunoglobulins plasma or different gammaglobulin preparations may be applied. The preparation of intravenous applicable preparations by different methods results in changes of half live times. The most important humoral immunodeficiency syndromes are the transitory hypogammaglobulinemia of infancy, the pathological hypogammaglobulinemia with delayed maturation of immunoglobulin-synthesis, the infantile X-linked agammaglobulinemia (Morbus Bruton) and the X-linked immunoglobulin deficiency syndrome with hyper-IgM. Intravenously applicable gammaglobulin preparations are preferred in the therapy the last two mentioned antibody deficiency syndromes which require large volumes. It has been demonstrated recently that these preparations are also suitable for continuous substitution.Read More
Publication Year: 1981
Publication Date: 1981-09-01
Language: en
Type: article
Indexed In: ['pubmed']
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